Clinical trials: Vitrectomy
Trauma, Macular Hole
Comparative Study Between Early Vitrectomy and Observation for Spontaneous Closure of Traumatic Macular Hole
The purpose of this study is to compare the anatomical and visual recovery of eyes with traumatic macular hole (TMH) following either early vitrectomy or 6-month observation.
- Trial name
- NCT01509092
- Testing
- vitrectomy surgery
- Where
- 8 sites in China
- Volunteers
- 44 people
- Sponsor
- Peking University Third Hospital
Diabetes, Diabetes Mellitus
Thrombospondin-1 and Pigmented Epithelium Derived Factor Levels in Patients With Diabetes Mellitus.
You are being asked to be in a research study to determine blood levels and vitreous levels of compounds called thrombospondin 1 (TSP1) and pigment epithelium derived factor (PEDF). These compounds exists naturally in your body.
- Trial name
- PEDF (NCT01809093)
- Testing
- Blood draw
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- MidAtlantic Retina
Retinal Detachment, Vitrectomy
Comparative Study of 1000 Centistoke Versus 5000 Centistoke Silicone Oil for Repair of Complex Retinal Detachments
The purpose of this study is to assess the retinal redetachment rates with 1000 centistoke versus 5000 centistoke silicone oil tamponade for repair of complex retinal detachments.
- Conditions
- Retinal Detachment, Vitrectomy, Proliferative Vitreoretinopathy, Diabetic Retinopathy
- Trial name
- NCT01255293
- Testing
- 1000 centistoke silicone oil, 5000 centistoke silicone oil
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Mid Atlantic Retina
Aqueous Tamponade, Cataract
Influence of Intravitreal Aqueous Tamponade on Lens Status and Ocular
To observe the effects of vitreous cavity Balanced salt solution (BSS) tamponade on the state of the lens and related parameters of the eye, and whether the changes of the above parameters are correlated with age, gender…
- Trial name
- NCT06133660
- Testing
- pars plana vitrectomy
- Where
- China
- Volunteers
- 21 people
- Sponsor
- Bo Jia
Corneal Epithelial Defects After Ocular Surgeries
Topical Autologous Insulin Application for the Treatment of Corneal Epithelium Defect After Ocular Surgeries
Topical insulin application has been proved recently to increase corneal reepithelization rate over diabetic animals. However, its effectiveness on corneal epithelial wound healing in patients who received pars planar vitrectomy…
- Trial name
- NCT01031888
- Testing
- Topical insulin eye drops, Conventional postoperative eye drops
- Where
- Taiwan
- Volunteers
- 18 people
- Sponsor
- National Taiwan University Hospital
Diabetic Retinopathy Patients After Vitrectomy
Comparison of the Visual Quality of Traditional Ultrasound Biometrics and Lenstar on the Cataract After Pars Plana Vitrectomy
Comparison of the visual quality of traditional ultrasound biometrics and lenstar on the cataract patients with diabetic retinopathy after vitrectomy in the 3 months later.To evaluate the clinical value of lenstar in…
- Trial name
- PPV (NCT03485586)
- Testing
- Traditional ultrasound biometrics, Lenstar
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Bojie Hu
Proliferative Diabetic Retinopathy, Vitrectomy
Observation of the Efficacy of Different Vitrectomy Systems to Treat Proliferative Diabetic Retinopathy
In recent years, vitrectomy has moved toward a minimally invasive vitrectomy surgery (MIV) system, which could effectively reduce the occurrence of operation complications, while reducing the time of post-operation recovery.
- Trial name
- NCT05446948
- Testing
- beveled 27G+ vitrectomy system, standard 25G+ vitrectomy system
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Tianjin Medical University Eye Hospital
Diabetes Mellitus, Diabetic Retinopathy
Intravitreal Long Acting Gas in the Prevention of Early Postoperative Vitreous Hemorrhage in Diabetic Vitrectomy
Recurrent vitreous hemorrhage after vitrectomy for complications of diabetic retinopathy is a common occurrence. The hemorrhage may appear within the first few weeks after surgery or months later.
- Conditions
- Diabetes Mellitus, Diabetic Retinopathy, Vitreous Hemorrhage
- Trial name
- NCT00155454
- Testing
- Intravitreal long acting gas (10% C3F8)
- Where
- Taiwan
- Volunteers
- 61 people
- Sponsor
- National Taiwan University Hospital
Optic Disc Pit Maculopathy
Vitrectomy for Optic Disc Pit Maculopathy
The purpose of this study is to evaluate the efficacy of vitrectomy, without gas tamponade or laser photocoagulation to the margin of the optic nerve, for the treatment of macular detachment associated with optic disc pits and to…
- Trial name
- NCT01340703
- Testing
- vitrectomy without laser or gas tamponade
- Where
- Japan
- Volunteers
- 8 people
- Sponsor
- Kyorin University
Suprachoroidal Hemorrhage (Diagnosis), Pars Plana Vitrectomy
Suprachoroidal Hemorrhage Associated With Pars Plana Vitrectomy
To analyze the characteristics, related risk factors, and prognosis of suprachoroidal hemorrhage (SCH) associated with pars plana vitrectomy (PPV).
- Trial name
- NCT05013281
- Testing
- Suprachoroidal hemorrhage associated with pars plana vitrectomy
- Where
- China
- Volunteers
- 28 people
- Sponsor
- Beijing Tongren Hospital
Proliferative Diabetic Retinopathy
Intravitreal Ozurdex After Pars Plana Vitrectomy for Proliferative Diabetic Retinopathy
To evaluate if intravitreal Ozurdex can reduce the incidence of recurrent vitreous hemorrhage after primary pars plana vitrectomy (PPV) in patients with proliferative diabetic retinopathy (PDRP).
- Trial name
- NCT01478737
- Testing
- Intravitreal dexamethasone implant, Vitrectomy
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Anders Kvanta
Retinal Detachment
Pressurized PPV 23GA Vitrectomy in Complicated Diabetic Tractional Retinal Detachment
To investigate the feasibility and advantages of using pressurized perfluorocarbon liquid (PCL) perfusion to remove vitreous during suction-cutting 23 GA vitrectomy using a dual, dynamic drive (3D)technology, in complicated…
- Trial name
- NCT00404209
- Testing
- Vitrectomy
- Where
- Mexico
- Volunteers
- 10 people
- Sponsor
- Asociación para Evitar la Ceguera en México
Eye Disease, Inflammation
Analysis of Eye Tissue
The purpose of this investigation is to better understand the inflammatory process that occurs in uveitis (eye inflammation) through study of eye tissues.
- Conditions
- Eye Disease, Inflammation, Uveitis
- Trial name
- NCT00001224
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- National Eye Institute (NEI)
Proliferative Diabetic Retinopathy
Vitrous Analysis in Proliferative Diabetic Retinopathy
Analysis of vitreous proteins in patients undergoing pars plana vitrectomy for proliferative diabetic retinopathy
- Trial name
- NCT01478763
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Anders Kvanta
Cataract, Juvenile
Optic Capture Without Anterior Vitrectomy in Pediatric Cataract Surgery
Purpose: To compare two pediatric cataract surgery procedures: intraocular lens (IOL) optic capture without anterior vitrectomy (AV) and in-the-bag IOL implantation with AV.
- Trial name
- NCT05461040
- Testing
- optic capture, In-the-bag implantation of Intraocular lens
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Ege University
Retinal Disease, Macular Retinoschisis
Pars Plana Vitrectomy Alone in the Treatment of Macular Schisis in High Myopic Eyes
High myopic schisis (HMF) has the clinical feature of separation between retinal layers. It is sometimes accompanied with foveal retinal detachment, macular lamellar hole, epiretinal membrane and vitreous retraction.
- Trial name
- NCT03586193
- Testing
- Pars plana vitrectomy
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Aier School of Ophthalmology, Central South University
Retinal Detachment, Macular Hole
Head Position Monitoring After Pars Planar Vitrectomy
In ophthalmic surgical practice, particularly for treating retinal detachment and macular hole disorders, vitrectomy procedures are routinely performed to remove the vitreous body followed by the injection of tamponade agents…
- Trial name
- HPMPPV (NCT06985030)
- Testing
- gyroscope embedded eye-sheild
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Hospital
Retinal Disease
Modified Soft Contact Lens During Vitrectomy
This study compared a modified soft contact lens with balanced salt solution irrigation during pars plana vitrectomy performed with a noncontact wide-angle viewing system.
- Trial name
- NCT07807436
- Testing
- Modified Soft Contact Lens, Balanced Salt Solution Irrigation
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Northwest University First Hospital (Xi'an No.1 Hospital)
Congenital Cataract
Comparison of Posterior Continuous Curvilinear Capsulorhexis With or Without Anterior Vitrectomy
Selecting the appropriate surgical approach for congenital cataracts presents challenging for ophthalmologists. This prospective, randomized controlled study aims to compare the prognosis of posterior continuous curvilinear…
- Trial name
- NCT05136209
- Testing
- PCCC procedure without A-vit, PCCC+A-Vit procedure
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Sun Yat-sen University
Retinal Detachment
Evaluation of Vitrectomy With ILM Peeling in Myopic Macular Hole With Only Posterior Retinal Detachment
Retinal detachment (RD) resulting from the macular hole (MH), also known as MH-induced RD (MHRD), most commonly occurs in eyes with high myopia and results in irreversible visual disorders.
- Trial name
- NCT06194760
- Testing
- Vitrectomy with ILM peeling
- Where
- Egypt
- Volunteers
- 13 people
- Sponsor
- Al-Azhar University