Clinical trials: Weaning
Infants Aged One Month to 2 Years , Infants With Any Type of Feeding (Breast or Artificial or Weaned Attend Assiut University Children Hospital )
Causes and Underlying Factors of Faltering Growth Among Infants
to research in the different causes of failure to thrive in children including organic and non organic causes
- Trial name
- NCT03283215
- Testing
- complete blood count , electrolytes
- Volunteers
- 100 people
- Sponsor
- Assiut University
Rapid Shallow Breathing
Prediction of Weaning Outcomes by Using Rate of Change of Rapid Shallow Breathing Index
This trial examines weaning outcomes using the rapid shallow breathing index rate.
- Trial name
- NCT00366197
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Atlantic Health System
Neonatal Respiratory Failure
Trial of Weaning by Synchronized Ventilation
During assist control ventilation and pressure support ventilation (PSV), the start of ventilator inflation is determined by the start of the infant's inspiratory effort.
- Trial name
- NCT01376544
- Testing
- Treatment protocol designed to evaluate (SLE 5000 ventilator)
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- King's College London
Infant, Newborn, Infant, Moderate Preterm
Incubator Weaning of Moderately Preterm Infants
The objective of this proposal is to evaluate whether weaning from an incubator to a crib at lower versus higher weight, 1600g or 1800g will result in shorter length of hospital stay among moderately preterm infants.
- Trial name
- NCT02160002
- Testing
- Weaning from an incubator at a lower weight (1600 grams), Weaning from an incubator at a higher weight (1800 grams)
- Where
- 18 sites in United States
- Volunteers
- 366 people
- Sponsor
- NICHD Neonatal Research Network
Premature Birth
E-23596 - Use of NCPAP Cycling to Wean Preterm Infants
Objective: To compare the effectiveness of nasal continuous positive airway pressure (NCPAP) cycling to continuous NCPAP in successful weaning of preterm infants of 25-28 weeks gestation to nasal prongs.
- Trial name
- NCT02114112
- Testing
- NCPAP cycling, NCPAP continuous
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Calgary
Persistent Pulmonary Hypertension of the Newborn, Inhaled Nitric Oxide
Close Loop Smart Weaning for INO With PPHN
In contemporary clinical practice concerning the administration of inhaled nitric oxide (iNO) within neonatal intensive care units (NICUs), a stepwise reduction approach is frequently employed in accordance with established…
- Trial name
- NCT06832163
- Testing
- Nitric Oxide Generation and Delivery System
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Children's Hospital of Fudan University
Respiratory Insufficiency
Effect of Sleep Disruption on the Outcome of Weaning From Mechanical Ventilation
Mechanically ventilated patients in the Intensive Care Unit (ICU) are highly susceptible to sleep disruption. Several studies in the last 15 years have demonstrated an extremely poor sleep quality and abnormal sleep pattern…
- Trial name
- SLEEWE (NCT02464735)
- Testing
- Polysomnography
- Where
- 3 sites in Canada
- Volunteers
- 44 people
- Sponsor
- Unity Health Toronto
Vegetable Acceptance in Early Childhood, Childhood Obesity
Baby's First Bites: Promoting Vegetable Intake in Infants and Toddlers
Overweight and obesity in preschool children is more and more common and predicts overweight in later childhood and adulthood. A healthy eating pattern with many vegetables decreases the risk to develop overweight.
- Conditions
- Vegetable Acceptance in Early Childhood, Childhood Obesity, Childhood Overweight
- Trial name
- NCT03348176
- Testing
- Vegetable exposure, VIPP-Feeding Infants, Control
- Where
- 2 sites in Netherlands
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Universiteit Leiden
Congenital Heart Disease
ATC Vs PSV for Ventilatory Weaning of Pediatrics Postcardiac Surgery
The ventilator modality of automatic tube compensation (ATC) can provide variable pressure supports during the weaning process to overcome any change in the resistance of the breathing circuit, endotracheal tube, and airways.
- Trial name
- NCT05344872
- Testing
- Weaning from mechanical ventilation
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- University of Alexandria
Iodine Deficiency Disorders
RCT of Iodine-containing MNPs vs Oral Iodized Oil to Prevent Iodine Deficiency in Weaning Infants
In this study, two intervention strategies to address iodine deficiency and prevent iodine deficiency disorders in breast-fed weaning infants will be evaluated in a mild to moderate iodine-deficient population in Zamboanga del…
- Trial name
- NCT02421653
- Testing
- MNP90, MNP45, IODISED OIL
- Volunteers
- healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Snake Bite, Weaning
Automatic Tube Compensation (ATC) for Weaning Patients With Severe Neurotoxic Snake Envenoming
In the mechanically ventilated patient, the single greatest cause of imposed work of breathing is the resistance caused by the endotracheal tube.
- Conditions
- Snake Bite, Weaning, Mechanical Ventilation
- Trial name
- ATC (NCT00804011)
- Testing
- ATC, PSV
- Where
- India
- Volunteers
- 41 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Respiration, Artificial
A Cluster Randomized Trial to Improve Weaning and Extubation From Mechanical Ventilation in Community Hospitals
Protocol directed weaning has been shown to reduce the duration of mechanical ventilation for patients admitted to the intensive care unit (ICU) of tertiary centres.
- Trial name
- NCT00157287
- Testing
- Evidence based weaning protocol
- Where
- 11 sites in Canada
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Weaning Failure
Interest of High Flow Nasal Cannula Oxygen Therapy in Pediatric Intensive Care Unit
monocentric randomized controlled trial starting from Mars 2017, recruitment is still ongoing. Patients aged between 0-45 days needing mechanical ventilation (MV) with tracheal intubation were included random assignation in two…
- Trial name
- NCT03505814
- Testing
- High Flow Nasal Cannula Oxygen therapy (OPTIFLOW®), Conventional oxygen therapy
- Where
- Tunisia
- Volunteers
- 126 people
- Sponsor
- Hôpital d'enfants Béchir-Hamza
Allergy
Tolerance of Cereals for Atopic Children
In this study, non allergenic cereals will be tested in infants with atopic symptoms. The test will be performed in a hospital.
- Trial name
- NCT01029184
- Testing
- commercialized complete cereals, commercialized complete cereals with additional ingredient
- Where
- Germany
- Volunteers
- 45 people
- Sponsor
- Société des Produits Nestlé (SPN)
ARDS (Acute Respiratory Distress Syndrome), AKI - Acute Kidney Injury
Renal Recovery After PEEP Weaning in ARDS (RE2SDRA)
The purpose of the study is to investigate renal recovery in ARDS after PEEP weaning. The primary outcome was the variation of the hourly urine output (HUO), 48 h after PEEP weaning.
- Trial name
- RE2SDRA (NCT06754787)
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Brest
Respiration, Artificial
A SBT-based Protocol-directed Program in Difficult-to-Wean Patients
Weaning patients from a ventilator is one of the most challenging processes in an intensive care unit. The investigators aimed to determine whether spontaneous breathing trial (SBT)-based protocol-directed weaning combined with…
- Trial name
- NCT05035355
- Testing
- a weaning protocol
- Where
- China
- Volunteers
- 200 people
- Sponsor
- JinyanXing
Apnea of Prematurity, Caffeine
Target Weaning Oxygen to Determine Cafffeine Duration for AOP
Caffeine, a typical representative of methylxanthine, is world-widely used to manage apnea of prematurity (AOP) in neonatology. However, an appropriate medication regimen of caffeine has not been well defined until now.
- Conditions
- Apnea of Prematurity, Caffeine, Weaning Oxygen, Medicine Regimen
- Trial name
- DCAP (NCT04868565)
- Testing
- Caffeine Citrate 20 MG/1 ML Intravenous Solution [CAFCIT]
- Where
- 41 sites in China
- Volunteers
- 310 people
- Sponsor
- Children's Hospital of Chongqing Medical University
Withdrawal Syndrome
Efficacy and Safety of Dexmedetomidine During Weaning From Analgesia and Sedation in PICU (TIP-15-01)
This interventional study evaluates the efficacy of dexmedetomidine during weaning from analgesic and sedative drugs in reducing the occurrence of the withdrawal syndrome in PICU.
- Trial name
- TIP-15-01 (NCT03645603)
- Testing
- Dexmedetomidine
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Hyperoxia, Hypoxia
Computer-assisted Oxygen Therapy Weaning in Critically Ill Children
The study is designed to evaluate the feasibility, safety and clinical utility of using an adaptive model to wean oxygen by computer assistance.
- Trial name
- NCT03550469
- Testing
- Computer-assisted Oxygen Weaning
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Stanford University
Mechanical Ventilator Weaning, Critically Ill
Neurally Adjusted Ventilatory Assist for Weaning From Invasive Mechanical Ventilation in Critically Ill Children
The goal of this clinical trial is to compare weaning from mechanical ventilation in critically ill children. The main questions it aims to answer are: Will weaning with neurally adjusted ventilatory assist (NAVA) mode…
- Conditions
- Mechanical Ventilator Weaning, Critically Ill, Mechanical Ventilation, Neurally Adjusted Ventilatory Assist
- Trial name
- NCT06157593
- Testing
- NAVA
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University