Clinical trials: Weaning Mechanical Ventilation
Mechanical Ventilation, Sedation
Sedation and Ventilator Weaning Protocol in PICU
This research is a single-blinded, randomized controlled trial involving mechanically ventilated children in Pediatric Intensive Care Unit, Cipto Mangunkusumo Hospital, Indonesia.
- Trial name
- NCT04788589
- Testing
- Sedation and ventilator weaning protocol
- Where
- Indonesia
- Volunteers
- 50 people
- Sponsor
- Universitas Indonesia
Bronchopulmonary Dysplasia
Pressure-Sensing Mattresses and Mechanical Ventilation Weaning in Neonatal
This study aims to explore the correlation between using ballistocardiography for monitoring respiration and heart rate in neonates under invasive and non-invasive respiratory support.
- Trial name
- NCT06579157
- Testing
- Pressure-Sensing Mattresses
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Fu Jen Catholic University
Mechanical Ventilator Weaning, Respiratory Muscle Training
Muscle Recruitment During Neck Flexion and Inspiratory Muscle Training
Respiratory muscle dysfunction is highly prevalent in patients with prolonged weaning from mechanical ventilation and is strongly associated with weaning failure.
- Trial name
- FLEX (NCT05710432)
- Testing
- Quasi-Isometric Neck Flexion, Inspiratory Muscle Training
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Unity Health Toronto
Anxiety, Cognitive Behavioral Therapy
Cognitive Behavioral Therapy for Mechanical Ventilation Wean
The purpose of this study is to use CBT strategies in assisting patients hospitalized in intensive care units in ventilation wean through a case series of 2 patients.
- Conditions
- Anxiety, Cognitive Behavioral Therapy, Mechanical Ventilation Complication
- Trial name
- NCT04763590
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Pennsylvania
Prone Position, Supine Position
The Effect of the Position Given to the Child After Weaning from Noninvasive Mechanical Ventilation on Physiological Symptoms
The aim of this clinical trial was to investigate the effect of the position given to children after weaning from noninvasive mechanical ventilation on the physiological symptoms (heart rate, oxygen saturation, respiratory rate…
- Conditions
- Prone Position, Supine Position, Child
- Trial name
- NCT06580522
- Testing
- Prone Position Group, Supine Position Group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Acibadem University
Weaning From Mechanical Ventilation in Care Unit
Prediction of the Spontaneous Breathing Test Success Using Biosignal and Biomarker in Critical Care Unit by a Machine Learning Approach
Context: Several authors have been interested in applying Artificial Intelligence (AI) to medicine, using various Machine Learning (ML) techniques: managing septic shock, predicting renal failure...
- Trial name
- NCT05886803
- Testing
- Spontaneous ventilation test
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Respiratory Insufficiency
Integrated Pulmonary Index (IPI) as a Determinate of Weaning Success and/or Failure in the Pediatric Population
Integrated pulmonary index (IPI) is a tool that monitors respiratory status. It takes into account four parameters: respiratory rate, end-tidal CO2, heart rate and O2 saturation using a pulse oximeter and specialized sidestream…
- Trial name
- IPI (NCT01795196)
- Where
- United States
- Sponsor
- Rush University Medical Center
High Velocity Nasal Insufflation, Simple Oxygen
A Randomized Clinical Trial for Predictors of Successful Extubation of Pediatric Patients With or Without High Velocity Nasal Insufflation
A randomized clinical trial about predictors of successful extubation of pediatric patients from mechanical ventilation either on High Velocity Nasal Insufflation or simple nasal oxygen and comparing the outcome
- Conditions
- High Velocity Nasal Insufflation, Simple Oxygen, Weaning Criteria
- Trial name
- NCT07383051
- Testing
- Comparing the outcome of pediatric patients after successful weaning on either High Velocity Nasal Insufflation or simple oxygen, comparing High Velocity Nasal Insufflation to simple oxygen after successful weaning of pediatric patients
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Respiratory Insufficiency
Effect of Sleep Disruption on the Outcome of Weaning From Mechanical Ventilation
Mechanically ventilated patients in the Intensive Care Unit (ICU) are highly susceptible to sleep disruption. Several studies in the last 15 years have demonstrated an extremely poor sleep quality and abnormal sleep pattern…
- Trial name
- SLEEWE (NCT02464735)
- Testing
- Polysomnography
- Where
- 3 sites in Canada
- Volunteers
- 44 people
- Sponsor
- Unity Health Toronto
Respiratory Mechanics, Monitoring, Physiologic
Dynamic Non-invasive Monitoring of Inspiratory Effort
This prospective, observational cohort study aims to evaluate whether the dynamic monitoring of a patient's breathing effort can predict successful liberation from invasive mechanical ventilation.
- Conditions
- Respiratory Mechanics, Monitoring, Physiologic, Respiratory Insufficiency Requiring Mechanical Ventilation, Critical Illness
- Trial name
- NCT07839949
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Fundació d'investigació Sanitària de les Illes Balears
Pediatric Liver Transplantation, Weaning From Mechanical Ventilation
NAVA vs PSV Ventilation During Weaning From Mechanical Ventilation in Children After Liver Transplantation
Liver transplantation is the treatment of choice for acute and chronic end-stage liver disease. Neurally Adjusted Ventilator Assist (NAVA) may be a feasible solution to guide the liberation from mechanical ventilation reducing…
- Trial name
- NAVIGATE (NCT04792788)
- Testing
- Weaning from mechanical ventilation
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Respiration, Artificial, Ventilator Weaning
Pressure Support Reduction Versus Spontaneous Breathing Trials in Weaning From Ventilation
This study is a comparison of two most commonly used modes of weaning and the outcomes in the two groups.
- Trial name
- NCT00911378
- Testing
- Pressure support ventilation, Spontaneous breathing trials
- Where
- India
- Volunteers
- 130 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Critical Illness
Specialized Treatment, Rehabilitation and Outcome in Patients With Prolonged Critical Illness
This prospective observational study aims to describe the outcome for patients with persistent or chronic critical illness treated at Remeo, a clinic specialized for patients in need of prolonged intensive care and intensive care…
- Trial name
- CritillPro (NCT04247607)
- Where
- Sweden
- Volunteers
- 250 people
- Sponsor
- Remeo AB
Prematurity, Apnea
Caffeine to Reduce Mechanical Ventilation in Preterm Infants
Most premature infants require mechanical ventilation for prolonged periods of time and a significant proportion of them develop Bronchopulmonary Dysplasia (BPD).
- Conditions
- Prematurity, Apnea, Respiratory Failure
- Trial name
- NCT01751724
- Testing
- Caffeine citrate, Normal saline
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- University of Miami
Respiratory Failure
Study to Improve Treatments and Follow-up of Children Who Need Respiratory Support
Mechanical ventilation is a vital therapeutic support, widely used in pediatric intensive care. Invasive ventilation (IV) is associated with risk of major complications ( nosocomial pneumonia, secondary pulmonary barotrauma…
- Trial name
- Edi-PTP (NCT02154542)
- Testing
- Neurovent Monitor XIII
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- St. Justine's Hospital
Mechanical Ventilation Weaning Phase in Children
Safety and Feasibility Study of a Mechanical Ventilation Computerized Protocol: Intellivent
The present protocol will demonstrate the safety, feasibility and efficacy of a newly computerized protocol integrated into a ventilator: S1 ventilator (Hamilton Medical).
- Trial name
- CloserPed (NCT01095406)
- Testing
- S1 ventilation
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- St. Justine's Hospital
Snake Bite, Weaning
Automatic Tube Compensation (ATC) for Weaning Patients With Severe Neurotoxic Snake Envenoming
In the mechanically ventilated patient, the single greatest cause of imposed work of breathing is the resistance caused by the endotracheal tube.
- Conditions
- Snake Bite, Weaning, Mechanical Ventilation
- Trial name
- ATC (NCT00804011)
- Testing
- ATC, PSV
- Where
- India
- Volunteers
- 41 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Ventilators, Mechanical, Work of Breathing
Effort of Breathing Guided Ventilator Protocol
This pilot study tests the feasibility of using a computerized ventilator management protocol seeking to encourage lung protective ventilation during the acute phase of ventilation, and esophageal manometry based titration of…
- Trial name
- EOBvent (NCT02989246)
- Testing
- Ventilator protocol, Esophageal Catheter
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Children's Hospital Los Angeles
Respiratory Failure
Weaning Children From Mechanical Ventilation:Computer-driven System Versus Usual Care
The purpose of this study is to determine whether a computer-driven system (Smartcare/PS) decreases weaning duration from mechanical ventilation when compared to usual care in children.
- Trial name
- NCT00678912
- Testing
- Smartcare/PS
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- St. Justine's Hospital
Mechanical Ventilation
Work of Breathing Assessment During Weaning From Mechanical Ventilation
Introduction In patients assisted by mechanical ventilation, the Work Of Breathing (WOB) is shared between the patient and the ventilator.
- Trial name
- WOAW (NCT02762292)
- Testing
- Measurement of work of breathing using indirect calorimeter
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- St. Justine's Hospital