Clinical trials: Wheat Hypersensitivity
Food Allergy, Wheat Allergy
Evaluation of Potential Allergenicity of New Wheat Varieties
The goal of the study is to determine accurate blood test levels that can predict whether or not subjects are truly allergic to certain foods.
- Trial name
- NCT02341040
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Food Allergy
ADP101 for Oral Immunotherapy in Food-Allergic Children and Adults
The purpose of this study is to assess the efficacy and safety of ADP101 in food allergic children and adults.
- Trial name
- NCT04856865
- Testing
- Low dose ADP101, High dose ADP101
- Where
- 15 sites in United States
- Volunteers
- 73 people
- Sponsor
- Alladapt Immunotherapeutics, Inc.
Non-celiac Wheat Sensitivity
Self-reported Gluten Sensitivity in High-school Students
It has been reported that a consistent percentage of the general population consider themselves to be suffering from problems caused by wheat and/or gluten ingestion, even though they do not have celiac disease or wheat allergy.
- Trial name
- NCT03021148
- Testing
- Questionnaire
- Where
- 2 sites in Italy
- Volunteers
- 500 people
- Sponsor
- University of Palermo
Allergy;Food, Wheat Allergy
Randomized Controlled Trial for Wheat Oral Immunotherapy
IgE-mediated wheat allergy is a growing allergy problem in children, and affected children can predict with immediate-type allergic reactions to the extent of anaphylactic shock.
- Conditions
- Allergy;Food, Wheat Allergy, Children
- Trial name
- WOIT-RCT (NCT06069492)
- Testing
- Wheat-containing food
- Where
- Hong Kong
- Volunteers
- 72 people
- Sponsor
- Chinese University of Hong Kong
Food Allergy
Use of Hypoallergenic (H.A.) Cereals in Children With Diagnosed Allergy to Wheat
The investigators plan to launch a Specific Oral Tolerance Induction (SOTI) pilot study in order to assess the efficacy and the safety of hypoallergenic (H.A.) wheat cereals, for children with allergy to wheat.
- Trial name
- NCT01332084
- Testing
- HA wheat cereals
- Where
- 2 sites in Switzerland
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Familial Mediterranean Fever, Non-celiac Gluten Sensitivity
Can Gluten/Wheat or Other Foods be Responsible for FMF Attacks
Familial Mediterranean Fever (FMF) is a chronic hereditary autoinflammatory disease caused by mutations in the MEditerranean FeVer (MEFV) gene which codes for pyrin.
- Trial name
- NCT06338891
- Testing
- Main questionnaire, Secondary questionnaire
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Palermo
Wheat Allergy, Anaphylaxis Food
Major Allergen in Wheat Anaphylaxis in Thai Population
To study Major allergen in Wheat anaphylaxis in Thai population To study and compare demographic data between group of wheat anaphylaxis
- Conditions
- Wheat Allergy, Anaphylaxis Food, Anaphylaxis Exercise
- Trial name
- NCT03487315
- Testing
- immunoblot
- Where
- Thailand
- Volunteers
- 36 people
- Sponsor
- Mahidol University
Food Allergy
Open-label Extension Study of ADP101
This is an open-label, safety extension study for participants who participated in the Harmony study (protocol ADP101-MA-01).
- Trial name
- NCT05243719
- Testing
- ADP101
- Where
- 14 sites in United States
- Volunteers
- 45 people
- Sponsor
- Alladapt Immunotherapeutics, Inc.
Wheat Allergy
Oral Immunotherapy for Wheat Allergy
This study is being done to learn about the medical effects, the safety, and the immunologic effects of Wheat Oral Immunotherapy (OIT) treatment.
- Trial name
- Wheat OIT (NCT01980992)
- Testing
- Wheat OIT
- Where
- 4 sites in United States
- Volunteers
- 46 people
- Sponsor
- Hugh A Sampson, MD
Food Allergy in Infants, Food Allergen Sensitisation
Human Breast Milk's Role in Food Allergy Development
The goal of this prospective cohort pilot study is to learn about food allergens being passed on in breast milk to breast feeding infants.
- Conditions
- Food Allergy in Infants, Food Allergen Sensitisation, Breast Feeding, Exclusive, Breastmilk Collection
- Trial name
- NCT06765213
- Testing
- Open Ended Oral Food Challenge, Early Introduction
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Wheat Hypersensitivity, Immunotherapy
Comparison Efficacy Between Two Different Frequency of Maintenance Dose Oral Immunotherapy
Oral immunotherapy(OIT) is effective in desensitized food allergy. OIT protocols are not standardized, and a wide heterogeneity exists in the literature .
- Trial name
- NCT06035328
- Testing
- Wheat (Four times per week)
- Where
- Thailand
- Volunteers
- 64 people
- Sponsor
- Mahidol University
Wheat Allergy, Child
The Natural History of Wheat Hypersensitivity in Thai Children
Wheat allergy is affected 0.4-1% and is a major staple of the worldwide diet. Wheat avoidance is exceedingly difficult and imposes major dietary restriction.
- Trial name
- NCT01801748
- Testing
- oral wheat challenge
- Where
- Thailand
- Volunteers
- 43 people
- Sponsor
- Mahidol University
Food Allergy, Wheat Hypersensitivity
A Study to Evaluate the Safety, Efficacy, Pharmacokinetic and Pharmacodynamic Characteristics of LP-003 Injection in Participants With Wheat Allergy
This is a multicenter, randomized, open-label Phase II clinical study to evaluate the safety, efficacy, pharmacokinetic (PK), pharmacodynamic (PD) and immunogenicity profiles of LP-003 injection in participants with Wheat…
- Trial name
- NCT07816432
- Testing
- LP-003 Injection
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Longbio Pharma (Suzhou) Co., Ltd.
Wheat Allergy
Luminex-based Assay to Identify Major IgE-binding Episode Among IgE-mediated Wheat-allergic Patient
This study will be using Luminex-based peptide assay (LPA) to determine major IgE-binding epitope among wheat allergic children to differentiate clinical phenotype.
- Trial name
- NCT04100122
- Testing
- Blood drawing
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Mahidol University
Wheat Allergy, Children
Outcome of Specific IgE Level in Children With IgE-mediated Wheat Allergy After Stop Using Wheat Containing Skin Care
Wheat allergy is increasing in Thailand. Some studies show that cutaneous exposure of allergen may cause allergy and there are many wheat containing skin care products that are over-the-counter.
- Trial name
- NCT04013763
- Testing
- wheat containing skin care products
- Where
- Thailand
- Volunteers
- 7 people
- Sponsor
- Mahidol University
Wheat Allergy
Oral Desensitization to Wheat in School Aged Children
The aim of the study is to induce tolerance to wheat in wheat allergic children via oral desensitization therapy. The hypothesis is that oral administration of wheat with increasing dosing will increase the individual threshold…
- Trial name
- NCT01755884
- Testing
- Wheat oral immunotherapy
- Where
- 4 sites in Finland
- Volunteers
- 100 people
- Sponsor
- Helsinki University Central Hospital
Allergy;Food, Allergy Wheat
Food Challenge With Barley Starch as Active Comparator
Aim of the present study is to verify in a double-blind placebo controlled food challenge (DBPCFC) test that highly purified barley starch ingredient do not cause allergic reaction in subjects most potential to get allergic…
- Trial name
- BALA (NCT03352856)
- Testing
- Barley starch, Maize starch
- Where
- Finland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lyckeby Starch AB
Wheat Allergy
Specific Oral Tolerance Induction (SOTI) to Children With IgE-mediated Wheat Allergy
This is an observational pilot study investigating the effectiveness, safety and specific immunological mechanisms of Specific Oral Tolerance Induction (SOTI) in children with IgE-mediated wheat allergy.
- Trial name
- NCT03352193
- Testing
- Wheat spaghetti
- Where
- Greece
- Volunteers
- 15 people
- Sponsor
- Athens General Children's Hospital "Pan. & Aglaia Kyriakou"
Wheat Allergy
Accuracy Of Skin Prick Test Using In-house Wheat Extract For The Diagnosis Of IgE-mediated Wheat Allergy: A Pilot Study
Nowadays, commercial wheat extract is widely accessible, and is used for skin prick test for wheat allergy. However, commercial wheat extracted for skin prick test have less precise test result compared to extract from omega-5…
- Trial name
- NCT01070368
- Testing
- Commercial extract and in-house wheat extract
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Mahidol University