Clinical trials: Wheeze
Infant Wheeze, Preschool Age Children
The Effectiveness of Early Immunisation With Nirsevimab on Preschool Wheezing in France, Based on an Analysis of Data From the French Health System Database.
Early respiratory syncytial virus (RSV) bronchiolitis is a well-known contributing factor of mid- and long-term respiratory sequelae in children such as recurrent lower tract respiratory infections (LRTIs), preschool wheezing…
- Conditions
- Infant Wheeze, Preschool Age Children, Asthma Childhood
- Trial name
- INSPIRATION (NCT07317141)
- Testing
- Effectiveness of passive immunization with nirsevimab
- Where
- France
- Volunteers
- 218,000 people
- Sponsor
- Hospices Civils de Lyon
Subject Presenting Wheeze, Asthma
AeviceMD for Detection of Wheeze in Pediatric and Adult Populations
Respiratory signs and symptoms consisting of wheeze, cough, and breathlessness are obtained in a manual fashion through history taking and physical examination by the healthcare professional.
- Conditions
- Subject Presenting Wheeze, Asthma, Bronchial Disease, Respiratory Tract Diseases
- Trial name
- NCT06691971
- Testing
- AeviceMD
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Aevice Health Pte. Ltd.
Subject Presenting Wheeze, COPD
Wheeze Detection Using Aevice Medical Device
The primary objective of this study is to determine if Aevice Medical Device can detect wheeze as accurately as a physician through auscultation.
- Conditions
- Subject Presenting Wheeze, COPD, Asthma
- Trial name
- NCT05194436
- Testing
- AeviceMD
- Where
- Singapore
- Volunteers
- 35 people
- Sponsor
- Aevice Health Pte. Ltd.
Asthma, Wheeze
Pediatric Arm of DZL All Age Asthma Cohort
Despite its common occurrence, still little is known about pathomechanisms determining different wheeze and asthma trajectories and phenotypes in children, and those beginning in adulthood.
- Conditions
- Asthma, Wheeze, Hypersensitivity, Endophenotype
- Trial name
- ALLIANCE (NCT02496468)
- Where
- 5 sites in Germany
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- LMU Klinikum
Recurrent Wheezes
Serum Levels of Vitamin D,Calcium and Magnesium in Preschool Recurrent Wheezers
wheezing" is defined as a musical sound caused by the passage of air through narrow respiratory tract airways . Recurrent wheeze is defined as three or more episodes of parentally reported wheeze in the past 12 months of Various…
- Trial name
- NCT05040269
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Asthma, Wheeze
The Development of Novel Clinical Tests to Diagnose and Monitor Asthma in Preschool Children
The study will ascertain the ability of preschool lung function tests to distinguish healthy children from those with wheeze, and to differentiate phenotypes of wheezy children (high and low risk for asthma as defined by API) in…
- Conditions
- Asthma, Wheeze, Obstructive Sleep Apnea, Food Allergy
- Trial name
- WheezyER (NCT02743663)
- Testing
- Bronchodilator response, Allergy Skin Test, Multiple-Breath Washout
- Where
- Canada
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Asthma, Status Asthmaticus
Steroids in Children Hospitalized With Asthma
Asthma is the most common chronic disease of children. A short (3-5 day) course of a short-acting steroid such as Prednisone or Prednisolone has long been the standard of care for asthma exacerbation.
- Conditions
- Asthma, Status Asthmaticus, Wheezes
- Trial name
- NCT02780479
- Testing
- Dexamethasone, Prednisone
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Florida
Pulmonary Function; Newborn, Abnormal, Infant Wheeze
Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function
Vitamin C supplementation (500 mg per day) given to pregnant women who can not quit smoking will improve the pulmonary function tests in their offspring measured at 3 months of age.
- Conditions
- Pulmonary Function; Newborn, Abnormal, Infant Wheeze, In-utero Nicotine, Second Hand Smoke
- Trial name
- VCSIP (NCT01723696)
- Testing
- Vitamin C +prenatal vitamin
- Where
- 2 sites in United States
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Wheeze
Combined Glucocorticoid Adrenergic Therapy For Wheezy Preschool Children
The investigators goal is to conduct a pilot randomized controlled trial (RCT) whose purpose is to determine the feasibility of a randomized trial designed to determine if either inhaled beclomethasone or a combination of inhaled…
- Trial name
- CONjuGATE (NCT02319564)
- Testing
- Beclomethasone, Beclomethasone and Salbutamol, Aerochamber Max®
- Where
- Canada
- Sponsor
- University of Calgary
Wheeze
Treating Wheezing in Children With Hypertonic Saline (TWICS)
Hypothesis: substitution of nebulized 3% NaCl (HS) for the standard normal saline (NS) used in bronchodilator therapy for acute viral wheezing in all children under age 6 years will provide superior symptom relief leading to…
- Trial name
- TWICS (NCT01868932)
- Testing
- hypertonic saline, saline
- Sponsor
- Dr. Michael Flavin
Non-Severe Pneumonia With Wheeze
Indiaclen Short Course Amoxycillin Therapy for Pneumonia With Wheeze
Background: The current Integrated management of childhood infections (IMCI) algorithm prescribes that children with wheeze and fast breathing presenting to first level health facilities are given antibiotics if they continue to…
- Trial name
- NCT00407394
- Testing
- Amoxycillin
- Where
- India
- Volunteers
- 2,000 people
- Sponsor
- King George's Medical University