Clinical trials: Wheezing
Wheezing, Asthma in Children
Impedance Pneumography in Assessment of Asthma Control in Preschool Children
This study evaluates the value of impedance pneumography, used as overnight home recordings during a longitudinal design, in assessing asthma control in preschool children
- Trial name
- IPAAC (NCT03377192)
- Where
- 2 sites in Finland
- Volunteers
- 53 people
- Sponsor
- HUS Skin and Allergy Hospital
Wheezing
Phenotypes of Preschool Wheezing Among Children Attending Sohag University Hospital
Wheezing in preschool children is very common, with a wide differential diagnosis. It is essential to be sure of the exact sound that parents are describing; the term 'wheeze' is often applied to non-specific sound.Approximately…
- Trial name
- NCT06603584
- Testing
- Chest x- Rays
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Asthma, Atopic Dermatitis
Polish Mother and Child Cohort Study (REPRO_PL) - Follow up of the Children.
The Polish Mother and Child Cohort is multicentre prospective study on different exposures. Prospective cohort study design enables identification of exposures that may influence pregnancy outcome and chil-dren's health…
- Conditions
- Asthma, Atopic Dermatitis, Food Allergy, Wheezing
- Trial name
- REPRO_PL (NCT01861548)
- Where
- 2 sites in Poland
- Volunteers
- 479 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz
Asthma, Acute Asthma
Budesonide for Emergency Treatment of Acute Wheezing in Children
The purpose of this study is to determine if adding nebulized budesonide to the systemic steroid for treatment of acute wheezing has any additive benefit in the emergency room.
- Trial name
- NCT00733317
- Testing
- 0.5 mg/ml budesonide nebules, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Kecioren Education and Training Hospital
Respiratory Sounds, Wheezing
Wheezometer™ Exploratory (WM) Field Study
Karmel Sonix Ltd has developed the Personal WheezoMeter a hand-held pulmonary sounds analyzer that utilizes contact sensors to acquire, amplify, filter, record and quantify the presence of wheezing.
- Trial name
- NCT01156818
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- KarmelSonix Ltd.
Wheezing
PREcision Medicine Directed Corticosteroids In Children With preSchool Wheeze
Young children frequently attend the emergency department (ED) with wheeze which is usually triggered by a virus infection, such as the common cold.
- Trial name
- PRECISE (NCT06580600)
- Testing
- Point of care respiratory virus testing
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Asthma, Wheezing
Evaluation of Toxic Metals, Trace Elements and Total Antioxidant Activity in Children With Recurrent Wheezing
The purpose of this study is to evaluate hair trace elements and toxic metals and plasma total antioxidant activity in children with recurrent wheezing and to evaluate whether these toxic metals and trace elements have any impact…
- Trial name
- NCT00749528
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Kecioren Education and Training Hospital
Asthma, Wheezing
Acetaminophen Versus Ibuprofen in Children With Asthma
The Acetaminophen Versus Ibuprofen in Children with Asthma study will test the primary hypothesis that in preschool children 12-59 months of age with persistent asthma on standardized asthma therapy, the number of asthma…
- Trial name
- AVICA (NCT01606319)
- Testing
- Acetaminophen, Ibuprofen
- Where
- 15 sites in United States
- Volunteers
- 300 people
- Sponsor
- Milton S. Hershey Medical Center
Acute Bronchiolitis
FeNO and Cytokines in Respiratory Syncytial Virus (RSV) and Non RSV Bronchiolitis in Relation to Future Asthma
The purpose of this study is to determine Fractional exhaled Nitric-Oxide (FeNO)levels and blood cytokines during acute bronchiolitis, and to seek for correlation between these markers and future development of asthma.
- Trial name
- NCT02093715
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Wheezing, Rhonchi
Clinical Evaluation of AI-aided Auscultation With Automatic Classification of Respiratory System Sounds
In the present trial, the StethoMe electronic stethoscope will be used for pulmonary auscultation and recording of lung sounds in the pediatric study population.
- Conditions
- Wheezing, Rhonchi, Crackle, Lung Sound
- Trial name
- AIR (NCT04208360)
- Testing
- StethoMe stethoscope
- Volunteers
- 84 people
- Sponsor
- StethoMe
Childhood Asthma With Acute Exacerbation
Antibiotic Treatment of Recurrent Episodes of Asthma in Children
Copsac has discovered that asthmatic exacerbations are as closely linked to bacterial as to viral infection. The current study will examine whether treatment of asthmatic exacerbations with macrolide antibiotics - in the abscence…
- Trial name
- AB-studie (NCT01233297)
- Testing
- Azithromycin
- Where
- 2 sites in Denmark
- Volunteers
- 70 people
- Sponsor
- Copenhagen Studies on Asthma in Childhood
Wheezing
Efficacy of Systemic Glucocorticoid in the Treatment of Wheezing in Children
We can not predict which wheezing child younger than 3 years of age benefits from systemic glucocorticoid and which one does not.
- Trial name
- VINKU (NCT00494624)
- Testing
- prednisolone
- Where
- Finland
- Volunteers
- 300 people
- Sponsor
- University of Turku
Bronchiolitis, Wheezing
Nebulized 3% Hypertonic Saline Solution Treatment of Bronchiolitis in Infants
Determine the efficacy of nebulized salbutamol/hypertonic saline combination in moderate to severe bronchiolitis.
- Trial name
- NCT02233985
- Testing
- 0.9% Sodium Chloride, 3% Sodium Chloride
- Where
- Mexico
- Volunteers
- 64 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Asthma, Wheezing
A Post Marketing Evaluation of the Effectiveness of FluMist Risk Minimization Plan in Children
This is a retrospective cohort study of children included in a large medical insurance claims database.
- Conditions
- Asthma, Wheezing, Immunosuppression
- Trial name
- NCT00626808
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 321,697 people
- Sponsor
- MedImmune LLC
Respiratory Ilness
Early Life Factors and Respiratory Health in Mexico City Children
Early life exposures now appear to be important in modulation of the immune response and tendency to develop asthma. We plan to enroll a cohort of children at birth to study early life factors in the development of wheezing and…
- Trial name
- NCT00342758
- Where
- 4 sites in United States, Mexico
- Volunteers
- 6,800 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Chronic Obstructive Pulmonary Disease
A Real-World Assessment of a COPD Disease Management Support Service (Me & My COPD)
A real world study to determine the effectiveness of a patient support service to aid COPD patients in their self management.
- Trial name
- Me&MyCOPD (NCT02300090)
- Testing
- Test Group, Control Group
- Where
- 23 sites in United Kingdom
- Volunteers
- 161 people
- Sponsor
- AstraZeneca
Respiratory Infections, Bronchiolitis
An Epidemiological Study to Evaluate the RSV-Associated Lower Respiratory Track in Infections in Infants
The primary objective of this study is to describe the incidence of RSV-associated LRI among infants <1 year of age presenting to the ED during selected shoulder months.
- Conditions
- Respiratory Infections, Bronchiolitis, Pneumonia, Apnea
- Trial name
- NCT00369759
- Testing
- Emergency Dept. Subjects with LRI or Apnea
- Where
- 38 sites in United States
- Volunteers
- 2,048 people
- Sponsor
- MedImmune LLC
Asthma, Smoking Cessation
Pediatric Emergency Department Decision Support System to Reduce Secondhand Smoke
This two phase study will develop and evaluate a Pediatric Emergency Department (PED) Decision Support System (DSS)-Electronic Medical Records (EMR) System to facilitate the identification of smokers and the delivery of a Second…
- Trial name
- NCT02489708
- Testing
- Cessation Counseling
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Asthma
Determinants Of Oral Corticosteroid Responsiveness in Wheezing Asthmatic Youth
The aim of the prospective cohort study is to: (1) document the magnitude of response to oral corticosteroids administered to children presenting to the emergency department with moderate or severe asthma and (2) quantify…
- Trial name
- DOORWAY (NCT02013076)
- Where
- 5 sites in Canada
- Volunteers
- 1,011 people
- Sponsor
- St. Justine's Hospital
Asthma
CARE Network Maintenance Versus Intermittent Inhaled Steroids in Wheezing Toddlers (MIST)
Asthma affects about 4 million children in the United States and is a leading cause of hospitalizations and school absenteeism. Continuous wheezing in very young children may develop into asthma.
- Trial name
- MIST (NCT00675584)
- Testing
- Budesonide
- Where
- 5 sites in United States
- Volunteers
- 278 people
- Sponsor
- Milton S. Hershey Medical Center