Clinical trials: Whole Body Imaging
Healthy, Serotonin Transporter
Brain Imaging of Serotonin Transporters in the Brain
Serotonin is a chemical involved in the regulation of emotions, anxiety, sleep, stress, and other body functions. The purpose of this study is to use brain imaging technology to study how serotonin works in the brain.
- Trial name
- NCT00059046
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Overweight, Obesity
Cue-Reward Learning and Weight Gain in Youth
The objective of the study is to compare children at low risk for obesity (two healthy weight parents) to children at high risk for obesity (two overweight parents) in their response rate to food taste and in their rate of…
- Trial name
- ChildLearn (NCT03254576)
- Testing
- Functional MRI
- Where
- United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Clinically Indicated MR Imaging
Imaging Techniques in Body Magnetic Resonance Imaging "MRI"
Any patient already receiving a scheduled MR scan of the body for any clinical indication will be eligible for this program.
- Trial name
- NCT00362557
- Testing
- MRI
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Alzheimer Disease, Dementia Alzheimers
Optical Coherence Tomography in Cerebral Amyloidosis
In this observational study, the investigators aim to evaluate whether changes in the retinal and choroidal circulation, as assessed by Optical Coherence Tomography (OCT) and the quantification of retinal amyloid deposits using…
- Conditions
- Alzheimer Disease, Dementia Alzheimers, Dementia, Lewy Body Disease
- Trial name
- NCT03472482
- Testing
- non-invasive retinal imaging
- Where
- Belgium
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Human Body Composition, Human Body Function
Development and Validation of Multi-nuclear Magnetic Resonance Imaging and Spectroscopy for Whole Body Human Applications
The purpose of this study is to develop and refine the techniques for using magnetic resonance imaging and magnetic resonance spectroscopy to understand the composition and function of the human body
- Trial name
- MRS VALIDATION (NCT02663362)
- Testing
- To evaluate the reproducibility of acquiring multi-nuclear data on a new 3T Philips Magnet
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Cardiomyopathies
Body Surface Area Prediction Impacts on Ventricular Dilatation Prevalence
The goals of this observational study are to investigate the accuracy of different predictive equations for body surface area (BSA) estimation and to evaluate the impact of different BSA normalizations on ventricular dilatation…
- Trial name
- NCT06939205
- Testing
- Assessment of body surface area and assessment ventricular dilatation prevalence
- Where
- Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Pediatric Obesity, Inhibition
Brain Mechanisms of Overeating in Children
The proposed research will follow healthy weight children who vary by family risk for obesity to identify the neurobiological and appetitive traits that are implicated in overeating and weight gain during the critical…
- Conditions
- Pediatric Obesity, Inhibition, Decision Making, fMRI
- Trial name
- RO1 (NCT03341247)
- Where
- United States
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Penn State University
Pediatric Obesity
Neural Mechanisms Underlying Children's Responses to Food Portion Size and Energy Density
Increased portion sizes of foods high in energy density (calories per gram of food) have been implicated in the obesity epidemic.
- Trial name
- NCT02759523
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Penn State University
Healthy
Positron Emission Tomography Imaging of Dopamine Receptors Using the Tracer [11C]NNC-112
This study will investigate the use of [11C]NNC-112 in positron emission tomography (PET) scanning. PET is a technique that uses radioactive isotopes called tracers to provide images of the brain.
- Trial name
- NCT00088517
- Testing
- [11C]NNC-112
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Obesity and Overweight
Brain and Behavior Influences on Obesity Development From Infancy Through Childhood
The investigators project, RESONATE, aims to investigate why some children develop obesity. To do this it uses data on eating and eating-related behaviors, genetic and environmental factors, and brain structure and function.
- Trial name
- RESONATE (NCT06861868)
- Testing
- fMRI cue reactivity task, fMRI go no go task, Ad libitum meal test
- Where
- 4 sites in United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Obesity, Childhood
Development of an Eating Behavior Risk Score
This study will explore how children's eating behaviors are connected to brain activity and body fat levels. Researchers are especially interested in a behavior pattern called the PACE phenotype, which includes how much children…
- Trial name
- PACE (NCT07266506)
- Testing
- Assessment of PACE Eating Phenotype and Related Behavioral and Neurobiological Measures
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Penn State University
Childhood Obesity
Brain Activation and Satiety in Children: Functional Magnetic Resonance Imaging
BASIC fMRI is a prospective single center intervention trial using fMRI imaging in 9-11 year old obese male and females pre and post family-based behavioral treatment of 24 weeks duration to determine the relationship between…
- Trial name
- BASIC-FMRI (NCT02484976)
- Testing
- Family Based Behavioral Treatment
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Obesity, Insulin Resistance
Neural Functioning of Feeding Centers in Obese Youth
To explore whether obese adolescents with insulin resistance and relative low leptin levels exhibit functional alterations of the neuronal circuits involved in the regulation of energy metabolism and food seeking behaviors.
- Trial name
- NCT01808846
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Yale University
Breast Cancer
Whole Body Magnetic Resonance Imaging (MRI) for Detection of Cancer Metastases
The objective of this pilot study is to develop and evaluate a whole body MRI technique for detecting cancer metastases. The whole body MRI will include T1-weighted and T2-weighted phase-sensitive MR imaging as well as diffusion…
- Trial name
- NCT00592462
- Testing
- Whole Body MRI
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Obesity, Childhood
Resilience to the Effects of Advertising in Children
Strong empirical evidence shows food marketing promotes excess energy intake and obesity. Yet, not all children are susceptible to its effects and this variability is poorly understood.
- Trial name
- REACH (NCT05073185)
- Where
- United States
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- Penn State University
Magnetic Field Exposure, Temperature Change, Body
Increase in Temperature in Children Undergoing MRI
An increasing number of children undergo Magnetic Resonance Imaging (MRI). In MRI, radio waves and magnetism are used to form images of the body's interior, to diagnose and monitoring diseases in children.
- Conditions
- Magnetic Field Exposure, Temperature Change, Body, Children, Only
- Trial name
- HOT-MR (NCT04317378)
- Testing
- Braun thermoscan /, IRT 6520
- Where
- Denmark
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pediatric Obesity
The Impact of Food Advertisements on Brain Response and Eating Behavior in Children
The purpose of this project is to examine the impact that television food advertisements have on brain responses and eating behavior in children.
- Trial name
- NCT02788838
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Penn State University
Obesity
Ultrasound Imaging For Facilitating Labour Epidurals in Obese Parturients
The efficacy of an epidural depends mainly on accurate placement of the catheter in the epidural space. Therefore, identification of the epidural space is the most vital part of the procedure.
- Trial name
- NCT00439998
- Testing
- Ultrasound
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Feeding Behavior, Brain
Food Intake and the Adolescent Brain
The brain plays an integral role in how and what people eat. However, the brain's contribution to overeating is not well understood during sensitive developmental periods such as adolescence, when excessive weight gain and…
- Conditions
- Feeding Behavior, Brain, Adolescent
- Trial name
- ADOB (NCT04208256)
- Testing
- Energy Stimulus
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Hepatic Steatosis, Obesity, Childhood
Attenuation Imaging in Hepatic Steatosis
For obese and normal-weight children, the investigators assess the diagnostic performance of attenuation imaging (ATI) in the detection of hepatic steatosis in children.
- Conditions
- Hepatic Steatosis, Obesity, Childhood, Ultrasonography
- Trial name
- NCT05302258
- Testing
- Attenuation imaging in ultrasonography
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital