Clinical trials: Workflow
Enamel Hypoplasia, Molar-Incisor Hypomineralization (MIH)
Clinical Comparison of CAD/CAM Nanohybrid Composite and Hybrid Ceramic Overlays in Children With Molar-Incisor Hypomineralisation
This clinical study was conducted to compare two different dental materials used in the treatment of children who have a condition called molar-incisor hypomineralization (MIH).
- Conditions
- Enamel Hypoplasia, Molar-Incisor Hypomineralization (MIH), Restoration of Permanent Molars Affected by MIH With CAD/CAM Blocks
- Trial name
- NCT06987448
- Testing
- Semi-direct onlay restoration using CAD/CAM hybrid composite block, Semi-direct onlay restoration using CAD/CAM hybrid ceramic block
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Alp Akça
Trauma, Congenital Bone and Joint Abnormalities
Telemedicine Consultation in Trauma and Orthopedic
The purpose of this study is to determine whether telemedicine consultations (lead by standard scheme)allows to increase quality of anatomical and functional outcomes and improve clinical work-flow at patients with acute bone and…
- Conditions
- Trauma, Congenital Bone and Joint Abnormalities, Joint Diseases, Orthopedic Surgery Complications
- Trial name
- TeleTO (NCT00815243)
- Testing
- Telemedicine consultation, Treatment plan
- Where
- 5 sites in Ukraine
- Volunteers
- 300 people
- Sponsor
- Donetsk National Medical University
Respiratory Tract Infections, Gastrointestinal Infection
Specimen Collection and Transport Workflow Evaluations for CLIA-waived Molecular Testing
The purpose of this study is two-fold. In the first phase, the goal is to characterize the stability of respiratory (nasal swab, nasopharyngeal swab, and throat swab; NS, NPS, TS) and stool (raw stool and rectal swab) specimens…
- Trial name
- NCT03299283
- Testing
- BioFire test platform
- Where
- United States
- Volunteers
- 4,000 people
- Sponsor
- BioFire Diagnostics, LLC
Nephrotic Syndrome
Implementation of a Diagnostic Workflow for Personalized Diagnosis of Nephrotic Syndrome
Nephrotic syndrome (NS) is a clinical picture common to several diseases resulting from damage to podocytes and glomerular filtration barrier.
- Trial name
- NCT06325098
- Testing
- Anti-nephrin antibodies, u-RPC cultures
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Meyer Children's Hospital IRCCS
Dehydration
Subcutaneous Recombinant Human Hyaluronidase: Workflow Analysis and Emergency Department Design
This is an observational study examining the workflow dynamics and training requirements that support effective use of subcutaneous hydration delivery (a newly FDA approved Baxter product) compared to standard intravenous…
- Trial name
- Hylenex-ED (NCT01020513)
- Sponsor
- University of California, San Diego
Bacterial Infections
Evaluation of a mNGS Workflow for Infection Diagnosis Using Oxford Nanopore Sequencing.
This is a laboratory evaluation of a new testing methodology for microbiological diagnosis, whereby participant samples received as part of routine care will be divided between the standard diagnostic pathway and this new…
- Trial name
- NCT04864873
- Testing
- Metagenomic next generation sequencing using Oxford Nanopore, Standard microbiological diagnostic pathway
- Where
- New Zealand
- Volunteers
- 400 people
- Sponsor
- Capital and Coast District Health board
Physician Workflow, Artificial Intelligence (AI)
A Randomized Controlled Trial of Ambient Artificial Intelligence Scribe Technologies
This is a three-arm pragmatic RCT of 238 outpatient physicians at a large academic health system, randomized 1:1:1 to one of two AI scribe tools or a usual-care control group.
- Trial name
- AIScribe RCT (NCT06792890)
- Testing
- Use Nabla AI Scribe tool provided, Use AI Scribe tool provided by Vendor B
- Where
- United States
- Volunteers
- 238 people
- Sponsor
- University of California, Los Angeles
Heart Disease, Dyspnea
Influence of Routinely Adding Ultrasound Screening in Medical Department
Ultrasound (US) is widely used as a diagnostic tool in a hospital setting. In a medical department, diagnosis like heart failure or most kinds of heart diseases, hypervolemia, hypovolemia, pleural effusion, pericardial effusion…
- Conditions
- Heart Disease, Dyspnea, Aortic Disease, Kidney Disease
- Trial name
- NCT01331187
- Testing
- Pocket-size ultrasonography, Usual care
- Where
- Norway
- Volunteers
- 600 people
- Sponsor
- Helse Nord-Trøndelag HF
Malocclusion, Angle Class I, Malocclusion, Angle Class II
AI-Assisted Versus Conventional Orthodontic Diagnosis and Treatment Planning
This study compared an artificial intelligence-assisted orthodontic diagnostic workflow using WebCeph with a conventional clinician-based workflow.
- Conditions
- Malocclusion, Angle Class I, Malocclusion, Angle Class II, Malocclusion, Angle Class III
- Trial name
- AI-OrthoDx (NCT07690774)
- Where
- Yemen
- Volunteers
- 120 people
- Sponsor
- Ben Hafeed Dental Center
Edentulous Alveolar Ridge Atrophy, ATROPHYC EDENTULOUS JAW
Assessment of the Accuracy of Full Digital Workflow in Patient Specific Submerged Subperiosteal Implants: A Case Series Study
custom made subperiosteal implants will be designed using the patients' CT data and will be inserted with the help of a surgical guide and loaded by a screw retained full arch prosthesis. accuracy will be assessed
- Conditions
- Edentulous Alveolar Ridge Atrophy, ATROPHYC EDENTULOUS JAW, Edentulous Maxilla, Edentulous Alveolar Ridge In Mandible
- Trial name
- NCT07014527
- Testing
- Patient specific subperiosteal implants
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Cairo University
Peripheral Venous Catheterization, Difficult Intravenous Access
TruVascular Access - Ultrasound-Guided Vascular Access Study
TruVascular Access - TVA-2026 is a prospective, randomized clinical study evaluating whether ultrasound-guided peripheral vascular access improves first-attempt cannulation success compared with conventional landmark…
- Conditions
- Peripheral Venous Catheterization, Difficult Intravenous Access, Catheterization, Peripheral
- Trial name
- TVA-2026 (NCT07798427)
- Testing
- Ultrasound-Guided Peripheral Vascular Access, Standard Peripheral Vascular Access, Point-of-Care Ultrasound System for Vascular Access Guidance
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Truway Health, Inc.
Surgical Education
Patient Specific Virtual Reality for Simulation of Spine Procedures: an Intelligent Image Segmentation, Registration and 3-dimensional Visualization in a Unified Virtual Reality Workflow for Image Guided Therapy, and Education - Physician Testing
The goal of this clinical trial is to learn if patient specific virtual reality (VR) simulations can be used for surgical orthopaedic education in resident and fellow physician populations.
- Trial name
- NCT06714539
- Testing
- Patient Specific Virtual Reality Stimulation
- Volunteers
- 13 people
- Sponsor
- Sunnybrook Health Sciences Centre
Mandibular Fractures
Specific Screw Holes Locating Surgical Guide and Pre-bent Plates
The aim of the current study was to evaluate the accuracy of computer-guided mandibular fracture reduction versus the classical work flow
- Trial name
- NCT05444829
- Testing
- specific screw holes locating surgical guide and pre-bent plates, classical reduction and internal fixation.
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Abdallah Gaber Ali Mohamed
Neurodevelopmental Disorders, Intellectual Disability
Multi-Omics Genetic Investigation Strategies to Enhance the Diagnostic Workflow for Rare Diseases
LEOPARD is a multicenter study aimed at improving the genetic diagnosis of patients with neurodevelopmental disorders (NDDs) of unknown etiology, particularly those with moderate-to-severe intellectual disability.
- Conditions
- Neurodevelopmental Disorders, Intellectual Disability, Autism Spectrum Disorder, Genetic Diseases, Inborn
- Trial name
- LEOPARD (NCT07884227)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Istituto Giannina Gaslini
Mandibular Class Iv Fractures
Patient-Specific Guides vs. Classical Workflow in Class IV Mandibular Fracture Fixation
This study aims to overcome the limitations of current, standard approach of mandibular fracture reduction and fixation including improper alignment of segments, malocclusion, nerve affections and related teeth roots injury.
- Trial name
- NCT07153354
- Testing
- patient-specific screw holes locating surgical guide and pre-bent plates, 2 titanium per-bent mini plates
- Volunteers
- 20 people
- Sponsor
- Mohamed abdelsalam Gaber elkhouly
Keratoconus, Refractive Surgery
AI-Orchestrated Workflow Versus Consultant Ophthalmologist for Refractive Surgery and Keratoconus Diagnosis (AEYE Trial)
Background and Rationale: Laser vision correction procedures, such as LASIK (Laser-Assisted In Situ Keratomileusis), PRK (Photorefractive Keratectomy), and SMILE (Small Incision Lenticule Extraction), are highly effective but…
- Conditions
- Keratoconus, Refractive Surgery, Machine Learning, Artifical Intelligence
- Trial name
- AEYE (NCT07096232)
- Testing
- Multi-Agent AI Diagnostic Workflow (AEYE)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Hazem Yassin Clinics