Clinical trials: Zinc Status
Zinc Deficiency
Efficacy of Zn Biofortified Wheat in Improving Zn Status in Indian School Children With Low Zn Status
The objective of this research is to test the efficacy of Zn biofortified wheat in increasing Zn status in Indian school children aged 6-12 y via a 6 month randomized controlled trial.
- Trial name
- NCT02241330
- Testing
- Biofortified wheat, Fortification, Control
- Where
- India
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Zinc Concentration in DBS
Nourishing for Knowledge: Fish Powder in School Meals in Malawi
Background: This randomized controlled trial (RCT) is a research component of a Food and Agriculture Organization of the United Nations (FAO) project in Malawi.
- Trial name
- FAO/LUANAR (NCT07085871)
- Testing
- Fish Powder
- Where
- 3 sites in Malawi
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Food and Agriculture Organization of the United Nations (FAO)
Iron Status, Vitamin A Status
Effect of African Leafy Vegetables on Nutritional Status of South African School Children.
The combination of poverty-related infectious and lifestyle-related non-communicable diseases, both driven by malnutrition, causes a high burden for South Africa.
- Conditions
- Iron Status, Vitamin A Status, Zinc Status, Malnutrition
- Trial name
- ALV (NCT01920646)
- Testing
- ALV
- Where
- South Africa
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- North-West University, South Africa
Micronutrient Status
Fortified Rice for School Children in Cambodia
Rice fortification has been shown to be safe and effective in improving micronutrient status in many studies around the world. However, most studies have been done in Latin America, Africa and India.
- Trial name
- FORISCA (NCT01706419)
- Testing
- Fortified rice cold extruded kernel, fortified rice warm extruded kernel, fortiified rice hot extruded kernel
- Where
- Cambodia
- Volunteers
- 9,500 people, healthy volunteers welcome
- Sponsor
- Institut de Recherche pour le Developpement
Cognitive Performance
Efficacy of a Milk-based Nutrient-rich Bar on Nutritional Status and Cognitive Performance of School Children in Vietnam
The objective of the study is to evaluate the impact of the milk-based nutrient-rich bar, specifically the effect of its fortification with zinc, iodine, vitamins A and D and calcium on nutritional status of school children…
- Trial name
- NCT01491581
- Testing
- food bar
- Where
- Vietnam
- Volunteers
- 415 people
- Sponsor
- Institut de Recherche pour le Developpement
Iron Deficiency, Vitamin A Deficiency
Nutritional Status and Bouillon Use in Northern Ghana
This pilot aims to generate data that are critical for informing the design of a planned, more detailed study to evaluate the effect of multiple micronutrient (MN)-fortified bouillon cube on biomarkers of nutrient status of women…
- Conditions
- Iron Deficiency, Vitamin A Deficiency, Vitamin B 12 Deficiency, Folate Deficiency
- Trial name
- NCT04632771
- Testing
- N/A (observational study)
- Where
- Ghana
- Volunteers
- 995 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Anemia
Regular Consumption of Leafy Vegetable Sauces and Micro-nutrient Status of Young Children in Burkina Faso
A food-to-food fortification strategy has been designed based on traditional foods of Burkina Faso to fight against micronutrient deficiencies in young children.
- Trial name
- Instapa-WP4 (NCT01724073)
- Testing
- Leafy vegetable-fish sauce, Leafy vegetable-fish/liver sauce, Misola
- Where
- Burkina Faso
- Sponsor
- Institut de Recherche pour le Developpement
Diarrhea, Respiratory Infection
Impact of Zinc Supplementation in Low Birth Weight Infants on Severe Morbidity, Mortality and Zinc Status: A Randomized Controlled Trial
There are currently no interventions available to substantially reduce the incidence of low birth weight (LBW) apart from increasing the age at marriage, maternal iron supplementation and possibly improved energy intakes.
- Conditions
- Diarrhea, Respiratory Infection, Low Birth Weight
- Trial name
- NCT00272142
- Testing
- Zinc
- Where
- India
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Society for Applied Studies
Pneumonia
Zinc as Adjunct to Treatment of Pneumonia
The propose of this study is to evaluate if zinc given as an adjunct to standard treatment of severe pneumonia in young children shortens the duration and reduces treatment failure, and if these effects are pathogen-dependant.
- Trial name
- EcuaPAZ (NCT00513929)
- Testing
- Zinc sulphate
- Where
- Ecuador
- Volunteers
- 450 people
- Sponsor
- Corporacion Ecuatoriana de Biotecnologia
Thalassemia, Splenectomy; Status
Zinc Supplementation on Cellular Immunity in Thalassemia Major
Randomized controlled trial was conducted in post-splenectomy patients aged >12 years. Subjects are randomly assigned to two groups (zinc and placebo). 1.5 mg/kg/day (max 50 mg/day) of Zinc is administered.
- Conditions
- Thalassemia, Splenectomy; Status, Immunosuppression
- Trial name
- NCT03117192
- Testing
- Zinc Sulfate, Sucrose Syrup
- Where
- Indonesia
- Volunteers
- 58 people
- Sponsor
- Fakultas Kedokteran Universitas Indonesia
Cystic Fibrosis
Zinc Homeostasis and Kinetics in Children With Cystic Fibrosis (CF)
Zinc deficiency has occasionally been reported in CF, but the need for additional zinc is unclear. We will examine the effect of additional zinc supplements on zinc absorption, zinc excretion, zinc balance and zinc kinetics in…
- Trial name
- NCT00104494
- Testing
- Zinc acetate (20mg/d)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cystic Fibrosis Foundation
Iron Overload, Oxidative Stress
Safety of Various Mode of Delivery of Iron Supplement on Iron Toxicity Markers in Preschool Children
The purpose of study is to evaluate and compare the effect of iron supplementation when given as iron tablet or fortified biscuit or combined with zinc in the form of tablet on morbidity and iron toxicity markers among children…
- Trial name
- NCT00980421
- Testing
- Iron Supplementation
- Where
- India
- Volunteers
- 240 people
- Sponsor
- Annamalai University
Cystic, Fibrosis
Zinc Status and Growth in Cystic Fibrosis
The purpose of this study is to improve the understanding of the relationship of zinc status and growth in infants and young children who were diagnosed with cystic fibrosis via newborn screening.
- Trial name
- NCT04302428
- Testing
- Serum Zn, Red Blood Cell Zn
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Indiana University
Vitamin A Deficiency, Iron-deficiency
Effect of Household Use of Multiple Micronutrient-fortified Bouillon on Micronutrient Status Among Women and Children in Two Districts in the Northern Region of Ghana
Background: Micronutrient (MN) deficiencies are severe and widespread in West Africa, particularly among young children and women of reproductive age.
- Conditions
- Vitamin A Deficiency, Iron-deficiency, Folate Deficiency, Vitamin B 12 Deficiency
- Trial name
- NCT05178407
- Testing
- Multiple micronutrient-fortified bouillon cube, Control bouillon cube (iodine-only)
- Where
- Ghana
- Volunteers
- 2,372 people
- Sponsor
- University of California, Davis
Zinc Deficiency
Water-based Zinc Efficacy Trial in Beninese Shool Children
The general objective of this study is to determine the effect of the daily consumption of zinc-fortified water provided by the LSF-filter on zinc status and diarrhea rates in school age children from rural areas characterized by…
- Trial name
- NCT01790321
- Testing
- LSF-filtering device
- Where
- Benin
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- Prof. Michael B. Zimmermann
Zinc Deficiency, Growth; Stunting, Nutritional
The Efficacy of Zinc-biofortified Rice in Bangladeshi Children
To assess the efficacy of the zinc biofortified rice on plasma zinc concentrations in infants from a rural area of Bangladesh.
- Trial name
- ZARI (NCT03079583)
- Testing
- Intervention-group, Control-group
- Where
- 2 sites in Bangladesh, Switzerland
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Deficiency Anemia
Nutrient Fortified Oat Drink
This study will follow a randomized, double-blind, placebo-controlled, parallel-group design to test if an oat beverage fortified with iron, zinc vitamin A and vitamin C will improve nutrient status and iron deficiency in young…
- Trial name
- NCT01418898
- Testing
- Dietary Intervention
- Where
- Philippines
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Anemia, Iron Deficiency
Effectiveness of Iron-Fortified Milk on Iron Status and Anemia in Young Children in Mexico
Iron deficiency and anemia in infants and young children impair neurodevelopment. Efficacious interventions for reducing the prevalences of iron deficiency and anemia, under controlled conditions, are available.
- Conditions
- Anemia, Iron Deficiency, Stunting
- Trial name
- NCT00508131
- Testing
- Whole Cows Milk
- Where
- Mexico
- Volunteers
- 798 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Salud Publica, Mexico
Zinc Deficiency
Impact of Targeted Zinc Fortification Programs on Plasma Zinc Concentration
The purpose of the study is to evaluate the use of plasma zinc concentration for assessing the impact of targeted zinc fortification programs.
- Trial name
- NCT00944398
- Testing
- Zinc fortified food, Zinc supplement, Non-fortified food
- Where
- Senegal
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Vitamin A Deficiency, Iron Deficiency
Effect Of Multiple Biofortified Food Crops On Micronutrient Status And Immune Function Among Indian Infants and Their Mothers
In this study, meals based on multiple food crops (containing either biofortified or commercially-available food crops) will be fed to young children in Madanapalle, Andhra Pradesh, India over a period of nine months to measure…
- Conditions
- Vitamin A Deficiency, Iron Deficiency, Zinc Deficiency
- Trial name
- MBFC (NCT02648893)
- Testing
- Multiple biofortified food crops (MBFC-Exp), Commercially available non-fortified food crops (MBFC-C)
- Where
- 2 sites in India
- Volunteers
- 200 people
- Sponsor
- Cornell University