Clinical trials: acne
Acne Vulgaris
Pilot Study of Tolerability and Effectivity of Two Combination Topical Acne Products
Study to compare two gels that are used to treat acne vulgaris. It will be compared the tolerability and effectivity following application of two combination topical acne products clindamycin 1% and 0.025% tretinoin gel (Acnatac®…
- Trial name
- PREFECT (NCT02731105)
- Testing
- Acnatac® Gel left face, Epiduo® Gel right face, Acnatac® Gel right face
- Where
- Germany
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- GWT-TUD GmbH
Acne Vulgaris
Investigating the Efficacy of Oral Probiotics Versus Placebo in Pakistani Patients With Moderate Acne on Acne Lesion Count and Systemic Inflammation
This randomized controlled trial evaluates the efficacy of oral probiotics compared to placebo in Pakistani patients with moderate Acne Vulgaris.
- Trial name
- Acne vulgaris (NCT07539129)
- Testing
- Probiotics
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Foundation University Islamabad
Acne Vulgaris
U0289-405: An Open-Label, 12-Week Study to Evaluate the Efficacy and Safety of the Acne System (Benzoyl Peroxide 2.5%, Salicylic Acid 0.5%) in Subjects With Acne
This study is being conducted to obtain safety, efficacy, and satisfaction data on the combination of topical Benzoyl Peroxide (BPO) 2.5% and the topical keratolytic agent Salicylic Acid (SA) 0.5% in the treatment of moderate to…
- Trial name
- NCT01446237
- Testing
- acne system - benzoyl peroxide 2.5%, Salicyclic Acid 0.5%
- Where
- 9 sites in United States
- Volunteers
- 125 people
- Sponsor
- Stiefel, a GSK Company
Acne Vulgaris
Study Comparing the Safety and Efficacy of IDP-120 Gel and IDP-120 Vehicle Gel in the Treatment of Acne Vulgaris
study designed to assess the safety, tolerability, and efficacy of IDP-120 Gel and IDP-120 Vehicle Gel
- Trial name
- NCT03664739
- Testing
- IDP-120 Gel, IDp-120 Vehicle Gel
- Where
- 30 sites in United States, Canada
- Volunteers
- 608 people, healthy volunteers welcome
- Sponsor
- Bausch Health Americas, Inc.
Acne
Patient Education in Adherence on Acne (PEAce)
This is a multi-center, randomised and controlled study in subjects with acne vulgaris. The main objective of this study is to evaluate the effect of a supplementary patient education intervention (in addition to the…
- Trial name
- NCT02307266
- Testing
- Standard of care + supplementary education, Standard of care + additional visits, Standard of care
- Where
- 10 sites in United Kingdom
- Volunteers
- 97 people
- Sponsor
- Galderma R&D
Food Sensitivities, Headache
NAET Screening for Food Allergy, Sensitivity and Intolerances Using IgE-Specific Antigen Test and NST- NAET®
Food allergy reactions cause various health disorders in sensitive people. These reactions may be IgE-mediated,cell-mediated, energy disturbance-mediated, or a combination of the three.
- Conditions
- Food Sensitivities, Headache, Backache, Indigestion
- Trial name
- NCT00275795
- Testing
- NAET Procedures
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Nambudripad's Allergy Research Foundation
Acne Vulgaris
Application of Epiduo(R) PUMP in Daily Practice in Patients With Inflammatory Acne
The purpose of this observational trial is to assess application and convenience of Epiduo® PUMP under daily clinical practice conditions in patients with moderate to severe inflammatory acne.
- Trial name
- PUMP-it (NCT02338544)
- Testing
- 0.1% Adapalene / 2.5% Benzoyl peroxide
- Volunteers
- 1,388 people
- Sponsor
- Galderma Laboratorium GmbH
Acne Vulgaris
Evaluation of the Effectiveness, Safety, and Tolerability of Duac Akne Gel and Epiduo Gel in the Treatment of Facial Acne Vulgaris
The purpose of this study is to compare the effectiveness of two marketed products in subjects with facial acne vulgaris
- Trial name
- NCT00757523
- Testing
- Epiduo Gel, Duac Gel
- Where
- 17 sites in Germany
- Volunteers
- 382 people
- Sponsor
- Stiefel, a GSK Company
Acne Vulgaris
Photoactive Porphyrins (PAP) Levels After Topical Visonac Application in Acne Patients
Open, prospective, randomized, single-centre study in patients with moderate to severe facial acne vulgaris. Three circular areas with a diameter of 4 cm, each circle including at least 4 inflammatory lesions, will be selected in…
- Trial name
- NCT01160848
- Testing
- Area cleaned with saline water and occluded with Tegaderm, Area cleaned with saline water, Area cleaned with Ethyl alcohol solution
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Photocure
Acne Vulgaris
Participant Reported Outcomes With Use of Trifarotene 50 μg/g Cream in the Treatment of Moderate Facial and Truncal Acne Vulgaris
Participant Reported Outcomes with use of Trifarotene 50 μg/g Cream in participants with Moderate Facial and Truncal Acne Vulgaris
- Trial name
- NCT03915860
- Testing
- Trifarotene
- Where
- 9 sites in United States
- Volunteers
- 47 people
- Sponsor
- Galderma R&D
Acne Vulgaris, Post Inflammatory Hyperpigmentation
Efficacy and Safety Study of Finacea to Treat Acne Vulgaris and Post-Inflammatory Hyperpigmentation (PIH)
Residual post-inflammatory hyperpigmentation (PIH)from acne is disturbing to individuals with skin of color. Finacea has been anecdotally known to be beneficial in resolving PIH related to acne vulgaris.
- Trial name
- NCT01038869
- Testing
- Azelaic acid
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Derm Research, PLLC
Acne Vulgaris
Double-Blind Efficacy and Safety of CD5789 (Trifarotene) 50µg/g Cream Versus Vehicle Cream in Acne Vulgaris
Assessment of the efficacy and safety of CD5789 (Trifarotene) 50µg/g cream applied once daily for 12 weeks in subjects with acne vulgaris.
- Trial name
- NCT02556788
- Testing
- CD5789 (trifarotene) 50µg/g Cream
- Where
- 81 sites in United States, Czechia and 6 more
- Volunteers
- 1,212 people
- Sponsor
- Galderma R&D
Acne Vulgaris
P3 Long Term Safety Study of Once Daily SB204 in Acne
This is a multi-center, open label long-term safety (LTS) study to be conducted in approximately 600 subjects with acne vulgaris.
- Trial name
- NCT02798120
- Testing
- SB204 4%
- Where
- 69 sites in United States
- Volunteers
- 601 people
- Sponsor
- Novan, Inc.
Inflammatory Acne Vulgaris
Pivotal Study of Sebacia Microparticles in the Treatment of Acne Vulgaris
Prospective, randomized multicenter study to examine the safety and effectiveness of Sebacia microparticles with or without laser in the treatment of moderate to moderately-severe inflammatory acne vulgaris
- Trial name
- NCT02217228
- Testing
- Sebacia microparticles and laser, Vehicle suspension and laser, Sebacia microparticles without laser
- Where
- 19 sites in United States
- Volunteers
- 394 people
- Sponsor
- Sebacia, Inc.
Vitiligo and Acne Vulgaris
Cutaneous JAK in Vitiligo and Acne Vulgaris.
The Janus kinase/signal transducer and activator of transcription (JAK-STAT) cytokine signaling pathway is an emerging area of interest in dermatology, and emerging evidence suggests that this pathway may play a crucial role in…
- Trial name
- NCT03185312
- Testing
- skin biopsy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Acne Vulgaris
A Long Term Study of GK530G in Subjects With Acne Vulgaris
This open label study is to determine the safety profile of GK530G in a long-term treatment (up to 12 months) in subjects with acne vulgaris and to evaluate the efficacy of GK530G in a long-term treatment.
- Trial name
- NCT01910064
- Testing
- GK530G
- Where
- 16 sites in Japan
- Volunteers
- 436 people
- Sponsor
- Galderma R&D
Acne Vulgaris
An Open-Label, Long-Term Extension Study to Evaluate the Safety of CB-03-01 Cream, 1% in Participants With Acne Vulgaris
The primary objective of this study is to determine the long-term safety of CB-03-01 cream, 1% applied twice daily for an additional nine months in study participants with acne vulgaris that participated in the Phase 3 pivotal…
- Trial name
- NCT02682264
- Testing
- CB-03-01 cream, 1%
- Where
- 74 sites in United States, Bulgaria and 5 more
- Volunteers
- 609 people
- Sponsor
- Cassiopea SpA
Acne
Musculoskeletal Effects of Isotretinoin During Acne Treatment in Pediatric Population
This is a prospective study, that will follow participants over their course of treatment on Isotretinoin. All patients who are prescribed Isotretinoin for their acne treatment are registered in iPLEDGE.
- Trial name
- NCT00964119
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Wisconsin, Madison
Acne Vulgaris
A Study of the Safety and Efficacy of DFD-03 for the Treatment of Acne Vulgaris
Enrollment of subjects with mild to moderate facial acne. Efficacy was assessed by using an Investigator's Global Assessment scale (IGA 5 point scale) and by counting the number of inflammatory and non-inflammatory lesions on the…
- Trial name
- DFD-03 (NCT03290027)
- Testing
- DFD-03
- Where
- United States
- Volunteers
- 550 people
- Sponsor
- Dr. Reddy's Laboratories Limited
Acne Vulgaris
Photodynamic Therapy in the Treatment of Acne
The purpose of this research project is to study the effect of non-ablative (non-cutting) laser therapy, a technique that uses laser energy to try to improve the appearance of the skin.
- Trial name
- NCT00613444
- Testing
- LumaCare LC-122M non-coherent light source
- Sponsor
- University of Michigan