Clinical trials: copd or chronic obstructive
Chronic Graft Versus Host Disease
Phase 1/2 Dose Finding and Safety Study of Ibrutinib in Pediatric Subjects With Chronic Graft Versus Host Disease (cGVHD)
Dose Finding and Safety Study of Ibrutinib in Pediatric Subjects with Chronic Graft Versus Host Disease (cGVHD)
- Trial name
- NCT03790332
- Testing
- Ibrutinib
- Where
- 48 sites in United States, Australia and 11 more
- Volunteers
- 59 people
- Sponsor
- Pharmacyclics LLC.
Osteoarthritis, Chronic Obstructive Pulmonary Disease
The Impact of Bundled Payments on Quality and Cost of Care
Bundled payment is a new payment reform that encourages health care providers to improve quality and contain costs of care. These arrangements are being rapidly expanded across the country, but evidence about their impact are…
- Conditions
- Osteoarthritis, Chronic Obstructive Pulmonary Disease, Pneumonia
- Trial name
- NCT02743507
- Volunteers
- 440 people
- Sponsor
- University of Pennsylvania
Hypertension, Diabetes
Development and Testing of a Sub-district Specific Model of 'Whole-of-government', and 'Whole-of-society' Approaches for the Prevention and Control of Non-communicable Diseases in a Sub-district of Bangladesh
Globally, non-communicable diseases (NCDs) are the leading cause of both mortality and morbidity. This intervention study aims to prevent and manage NCDs by adopting the World Health Organization's (WHO) comprehensive…
- Conditions
- Hypertension, Diabetes, Asthma, Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- NCT06453382
- Testing
- Behavioural change modification, Screening, NCD related knowledge practice and attitude
- Where
- Bangladesh
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- BRAC University
Shortness of Breath, Chest Pain
Checklists Resuscitation Emergency Department
The study will systematically evaluate how an emergency manual-a collection of checklists and fact sheets-affects the performance of resuscitation teams during the management of priority one patients in an emergency department.
- Conditions
- Shortness of Breath, Chest Pain, Abdominal Pain, Altered Mental Status
- Trial name
- NCT05649891
- Testing
- Emergency Manual
- Volunteers
- 2,000 people
- Sponsor
- Region Skane
Chronic Obstructive Pulmonary Disease
Home Mechanical Ventilation in Patients With Chronic Obstructive Pulmonary Disease (COPD) and Hypercapnic Response
The objective of this study is to evaluate the clinical benefits of home mechanical ventilation associated to oxygen therapy in COPD patients with chronic respiratory failure (CRF) who develop hypercapnia and nocturnal…
- Trial name
- NCT01120574
- Testing
- Home mechanical ventilation
- Where
- Spain
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Emphysema or COPD
Introduction of the Vapor Treatment in The Netherlands
Rationale: The bronchoscopic lung volume reduction treatment using vapor was found to be effective and the treatment has an acceptable safety profile.
- Trial name
- NEVEL (NCT04029077)
- Testing
- NA: intervention is not part of the study
- Sponsor
- University Medical Center Groningen
Asthma Exacerbation, COPD Exacerbation
A Study Evaluating the Use of ResAppDx v2.0 as an Aid to Diagnose Respiratory Disease in Adolescent and Adult Patients in an Emergency Department
Aim is to to demonstrate that the ResAppDx v2.0 algorithms provide an accurate diagnosis of respiratory disease in the study's clinical setting compared to a clinical adjudication committee's (CAC) diagnosis; and to establish a…
- Conditions
- Asthma Exacerbation, COPD Exacerbation, Lower Respiratory Disease, Pneumonia
- Trial name
- NCT06156462
- Testing
- ResAppDx v.20
- Where
- 3 sites in United Kingdom
- Volunteers
- 171 people
- Sponsor
- ResApp Health Limited
Burns, Knee Injuries
Opioid Laws and Pediatric Use
The legitimate need for opioid medications for acute pain management in pediatric trauma patients is recognized, however, the high dose and duration of opioid drugs prescribed by medical providers has been associated with an…
- Conditions
- Burns, Knee Injuries, Opioid Use, Pain
- Trial name
- NCT04543227
- Testing
- Opioid Use 90-Days Post Treatment
- Where
- United States
- Volunteers
- 980 people
- Sponsor
- Nationwide Children's Hospital
Hemolytic Anemia, Chronic, Liver Diseases
Predisposing Factors for Liver Diseases in Patients With Chronic Hemolytic Anemia
The goal of this observational study is to detect risk factors for liver affection in patients with chronic hemolytic anemias presented to the hematology unit.
- Trial name
- NCT06743854
- Volunteers
- 58 people
- Sponsor
- Assiut University
Advanced Lung Disease, COPD
Effect of Inpatient Pulmonary Rehabilitation on Frailty in Candidates for Lung-Transplantation
Frailty in lung transplant candidates increases the risk of delisting and adverse transplantation outcome [1]. Furthermore, preoperative frailty is associated with a higher one-year-mortality rate after transplantation in frail…
- Conditions
- Advanced Lung Disease, COPD, ILD
- Trial name
- NCT03895931
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Schön Klinik Berchtesgadener Land
Pulmonary Disease, Chronic Obstructive, Bronchospasm
Prophylactic Efficacy of Relenza Against Influenza A and B
In response to the European regulatory authorities, GSK is conducting a post-marketing observational study to assess the efficacy of Relenza when used as prophylaxis against influenza. SPECIFIC AIMS 1.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Bronchospasm, Influenza, Human, Asthma
- Trial name
- NCT01156701
- Testing
- Receiving a prescription of Relenza for prophylaxis, No prophylaxis with Relenza
- Volunteers
- 171,705 people
- Sponsor
- GlaxoSmithKline
Chronic Obstructive Airways Disease Exacerbated, Critical Care
Survival After Failed First-line Non-invasive Ventilation in Acute on Chronic Obstructive Pulmonary Disease
Observational cohort study of mid-to-long term survival of patients with acute on chronic obstructive pulmonary disease, analyzed per type of ventilation support provided during first 24 hours in intensive care.
- Trial name
- NCT03011853
- Testing
- Non-invasive and/or invasive mechanical ventilation
- Where
- Sweden
- Volunteers
- 7,900 people
- Sponsor
- Swedish Intensive Care Registry
Asthma, Lung Diseases, Obstructive
Early Risk Predictors For Chronic Pulmonary Disease
To continue to evaluate risk factors heretofore determined to be important predictors of chronic respiratory symptoms, diagnosis of asthma, and alterations in expected levels of lung function in children and adolescents in a new…
- Conditions
- Asthma, Lung Diseases, Obstructive, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT00005281
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Asthma
Chronic-Dose Safety and Efficacy Study of Albuterol-HFA-BAI in Pediatric Asthmatics
This study is designed to evaluate the repeat-dose safety and effectiveness of a bronchodilator inhaler relative to placebo (inactive drug inhaler) in children aged 4-11 years with asthma.
- Trial name
- NCT00308685
- Testing
- Albuterol
- Where
- 14 sites in United States
- Volunteers
- 95 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Chronic Obstructive Pulmonary Disease
A Trial to Assess the Pharmacodynamic Response in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
This is a randomized, double-blind, multi-dose, parallel group trial which will assess the pharmacodynamic response of fluticasone propionate and formoterol fumarate in subjects with COPD.
- Trial name
- NCT01168310
- Testing
- Fluticasone Propionate/Formoterol Fumarate, Formoterol Fumarate
- Where
- 23 sites in United States
- Volunteers
- 468 people
- Sponsor
- Dey
COPD
Impact of Ibis on Patients With Advanced COPD
The purpose of this research is to determine if Ibis™, a digital therapeutics solution developed by Senscio Systems, reduces the emergency room visits and hospitalizations of patients with COPD.
- Trial name
- NCT03131622
- Testing
- Digital Therapeutics
- Volunteers
- 240 people
- Sponsor
- Senscio Systems
Chronic Obstructive Pulmonary Disease COPD
Realize the Current Situation of COPD Patients in China
This is a multi-centre, prospective, observational study to realize the current situation of COPD patients in China. About 5000 COPD patients will be enrolled from 50 participating sites around China and followed up for one year.
- Trial name
- REAL (NCT03131362)
- Where
- China
- Volunteers
- 5,020 people
- Sponsor
- AstraZeneca
COPD
Impact of Walking Behind the COPD Patient on 6MWD
The six-minute walk test (6MWT) is a well established field exercise test to assess the functional exercise capacity in chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT04033783
- Testing
- 6MWT - accompanied, 6MWT - not accompanied
- Where
- 2 sites in Switzerland
- Volunteers
- 49 people
- Sponsor
- University of Zurich
Chronic Myeloid Leukemia (CML)
Chronic Myeloid Leukemia (CML) Real-Life Database
Establish the largest possible real-life cohort collecting long-term follow-up of a maximum number of CML patients in order to carry out observational studies: epidemiological, identification of subgroups according to their…
- Trial name
- NCT05963061
- Where
- 14 sites in France
- Volunteers
- 3,500 people
- Sponsor
- University Hospital, Clermont-Ferrand
Bronchiolitis Obliterans Syndrome
Early Detection and Management of Bronchiolitis Obliterans Syndrome Following Pediatric Hematopoietic Stem Cell Transplantation
This study aims to determine whether or not early spirometric detection and management of obstructive lung disease with combined fluticasone/azithromycin/montelukast therapy (FAM) can attenuate declining lung function, prevent…
- Trial name
- NCT03072849
- Testing
- Pulmonary function testing, FAM Therapy
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago