Clinical trials: in Vitro Activation
Assisted Reproduction
Small Molecule LCDM and GV Oocyte
Immature eggs obtained during the oocyte retrieval cycle are discarded as medical waste because they cannot complete fertilization, but each egg is important for people with poor clinical outcome.
- Trial name
- NCT05356429
- Testing
- Small molecule LCDM
- Volunteers
- 250 people
- Sponsor
- Peking University People's Hospital
Food Allergy
Basophile Activation Testing (BAT) in Hazelnut Allergy (Hazelnut BAT Study)
The proposed study intends to compare the outcome of food challenge in hazelnut allergic patients with the outcome of basophile activation tests using hazelnut extract and components.
- Trial name
- NCT03079206
- Testing
- Food challenge, skin testing, blood sampling
- Where
- Switzerland
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Congenital Heart Disease, Fibrinolysis
Determination of the Minimal Concentration of Antifibrinolytics Required to Inhibit t-PA-activated Fibrinolysis
Lysine analogs, like tranexamic acid (TXA) or epsilon aminocaproic acid (EACA), are antifibrinolytic agents routinely administered in children undergoing different surgeries associated with a high bleeding risk (e.g.
- Conditions
- Congenital Heart Disease, Fibrinolysis, Rotational Thromboelastometry
- Trial name
- NCT02352675
- Testing
- Intraoperative Blood Sample
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Boston Children's Hospital
Hypogonadism, Estrogens
Development and Validation of in Vitro Cell-based Bioassays for Nuclear Receptor Activation
This is a prospective biobank set up to collect serum from patients with disorders associated with changes in androgens, estrogens or sex hormone-binding globulin (SHBG), before and/or after treatment.
- Conditions
- Hypogonadism, Estrogens, Testosterone, Androgens
- Trial name
- NCT02434562
- Testing
- Serum (with or without urine) samples
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Acute Myeloid Leukemia
Natural Killer Cells Infusion for Treating Acute Myeloid Leukemia Patients With Minimal Residual Disease
This trial will evaluate the effectiveness and safety of haploid donor-derived in vitro activated natural killer(NK) cells infusion for Treating acute myeloid leukemia Patients With minimal residual disease.
- Trial name
- NCT04209712
- Testing
- haploid allogeneic NK cell therapy
- Where
- China
- Volunteers
- 6 people
- Sponsor
- Shanghai iCELL Biotechnology Co., Ltd, Shanghai, China