Clinical trials: mRNA Expression
Asthma
mRNA Expression as a Biomarker of Omalizumab Response
Objectives: 1. Determine if mRNA expression could be use as a biomarker to predict and monitor the response to omalizumab in patients with difficult control asthma 2.
- Trial name
- NCT01584687
- Testing
- Omalizumab
- Volunteers
- 6 people
- Sponsor
- Instituto de Investigação em Imunologia
Attention Deficit Hyperactivity Disorder (ADHD)
Plasma Orexin A and mRNA Expression Levels of Pre-pro-orexin Gene in Attention-Deficit Hyperactivity Disorder
Background: Attention deficit hyperactivity disorder (ADHD) is an early onset, highly heritable, clinically heterogeneous, long-term impairing disorder with tremendous impact on individuals, families, and societies.
- Trial name
- NCT02074176
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Postural Tachycardia Syndrome
POTS NET mRNA Functional Correlation With NET Activity
DNA Acetylation can be responsible for significant down-regulation of transcription of the Norepinephrine Transporter (NET). NET is an important clearance transporter that removes norepinephrine (NE) from sympathetic neuronal…
- Trial name
- NCT03218761
- Testing
- NET mRNA level, Plasma catechols, Urine Catechols
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Heart Transplantation, Kidney Transplantation
Effects of Donor and Recipient Genetic Expression on Heart, Lung, Liver, or Kidney Transplant Survival
Activity of genes in donor tissues that are involved in inflammation are thought to be involved with early organ dysfunction, increased immune responses in transplant recipients, and organ rejection.
- Conditions
- Heart Transplantation, Kidney Transplantation, Liver Transplantation, Lung Transplantation
- Trial name
- NCT00531921
- Where
- 5 sites in United States
- Volunteers
- 313 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Preterm Birth, Premature Rupture of Membranes
Microarray Expression Profiling to Identify Stereotypic mRNA Profiles in Human Parturition
The understanding of the biological mechanisms underlying preterm birth is very limited, making prevention of preterm birth difficult.
- Trial name
- NCT00342277
- Where
- 4 sites in United States, Chile and 2 more
- Volunteers
- 6,838 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Pancreas Cancer
ITGA2b and SELP Expression in Cancer Pancreas and Biliary Tract Cancer
1. To study the expression pattern of Integrin alpha 2b (ITGA2b) and Selectin P (SELP) genes of Tumor educated platelets in pancreatic and biliary tree cancer and its diagnostic value. 2.
- Trial name
- NCT05493878
- Testing
- mRNA expression
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Assiut University