Clinical trials: tDCS
Lennox-Gastaut Syndrome
Transcranial Direct Current Stimulation, Treatment of Childhood Drug-Resistant Lennox-Gastaut Syndrome, A Pilot Study
Background: Lennox-Gastaut syndrome (LGS) is a severe childhood epileptic syndrome with high pharmacoresistance. The treatment outcomes are still unsatisfied.
- Trial name
- NCT02731300
- Testing
- tDCS
- Volunteers
- 22 people
- Sponsor
- Khon Kaen University
Transcranial Direct Current Stimulation, Autistic Spectrum Disorder
Cumulative and Booster Effects of Multisession Prefrontal Transcranial Direct Current Stimulation in Adolescents With ASD
Autism spectrum disorder (ASD) is a pervasive and lifelong developmental disorder that currently affects 1 in 54 children. Individuals with autism are often severely impaired in communication, social skills, and cognitive…
- Conditions
- Transcranial Direct Current Stimulation, Autistic Spectrum Disorder, Electroencephalography, Booster Effects
- Trial name
- NCT05492032
- Testing
- Active-tDCS, Cognitive training
- Where
- Hong Kong
- Volunteers
- 150 people
- Sponsor
- The Hong Kong Polytechnic University
Disorders of Consciousness, Severe Brain Injury
Effect of Repeated tDCS Sessions on Cognitive Improvement in Patients With Disorders of Consciousness
In this study, researchers will show to caregivers of patients how to use a tDCS device (this device was designed to be easy to use, with fixed parameters and only one button to press to run the stimulation).
- Conditions
- Disorders of Consciousness, Severe Brain Injury, Post-comatose Non-communicative Patients
- Trial name
- rtDCS in DOC (NCT02394691)
- Testing
- transcranial direct current stimulation
- Where
- Belgium
- Volunteers
- 37 people
- Sponsor
- University of Liege
Disorder of Consciousness
Transcranial Direct Current Stimulation in Patients With Disorders of Consciousness
To date, several studies have focused on the use of transcranial direct current stimulation(tDCS) in patients with impaired consciousness.However,its therapeutic effects have been variously documented.So,in this study…
- Trial name
- NCT03809936
- Testing
- real tDCS
- Where
- China
- Volunteers
- 33 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Depression, Depressive Disorder
Mindful Breathing and tDCS for Depression
This study will investigate whether transcranial direct current stimulation (tDCS) targeting the dorsolateral prefrontal cortex (DLPFC) can enhance the therapeutic effect of mindful breathing training (MBT) for adolescent…
- Trial name
- NCT03897699
- Testing
- Transcranial Direct Current Stimulation, Mindful Breathing
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of Minnesota
Other Forms of Epilepsy, Treatment Resistant
TDCs to Treat Drug-resistant Epilepsy
Epilepsy is the fourth overall neurologic disorder, regardless of age and gender, affecting more than 50 million people worldwide.
- Trial name
- NCT05825274
- Testing
- Active Cathodal tDCS
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Spanish Foundation for Neurometrics Development
COVID-19, Long COVID
Effectiveness of Transcranial Direct Current in Patients With Persistent COVID-19 With Headaches and Chronic Pain.
This study aims to verify the efficacy/effectiveness of treatment with transcranial direct current stimulation (TDCS) in patients with Long Covid who experience headaches, migraines, and chronic pain, such as arthralgia and…
- Conditions
- COVID-19, Long COVID, Long Covid19, SARS CoV 2 Infection
- Trial name
- NCT05780450
- Testing
- Transcranial Direct Current Therapy (tDCS)
- Where
- 2 sites in Spain
- Volunteers
- 87 people
- Sponsor
- Fundación Universidad Católica de Valencia San Vicente Mártir
Obsessive-Compulsive Disorder, Pediatric Psychiatric Disorder
Transcranial Direct Current Stimulation (tDCS) in Pediatric Obsessive Compulsive Disorder (OCD)
In this study, the investigators aim to understand the role of transcranial direct current stimulation (tDCS) in modulating aberrant neurocognitive processes implicated in pediatric patients with obsessive compulsive disorder…
- Trial name
- NCT04548609
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Massachusetts General Hospital
Vegetative State, Minimally Conscious State
Transcranial Direct Current Stimulation in Patients With Disorders of Consciousness
Previous studies showed that anodal transcranial direct current stimulation (tDCS) applied to the left dorsolateral prefrontal (DLPF) cortex transiently improves performance of memory and attention.
- Conditions
- Vegetative State, Minimally Conscious State, Disorders of Consciousness
- Trial name
- tDCS in DOC (NCT01673126)
- Testing
- Anodal tDCS
- Where
- Belgium
- Volunteers
- 55 people
- Sponsor
- University of Liege
Epilepsy, Drug Resistant Epilepsy
Efficacy of Personnalized Transcranial Direct Current Electrical Stimulation (tDCS) in Drug-resistant Epileptic
The goal of this clinical trial is to to obtain a significant decrease in seizure frequency in patients with refractory focal epilepsy after applying treatment of cathodal tDCS, compared to sham stimulation drug-resistant…
- Trial name
- GALVANI GS-3 (NCT06334952)
- Testing
- transcranial direct current stimulation
- Where
- 7 sites in France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Aphasia Non Fluent, Stroke
Effectiveness of TDCS Over Broca's Area in Verb Naming: a Randomized, Double-Blind, Crossover Study
This clinical trial investigated whether transcranial direct current stimulation (tDCS) over Broca's area (F5) could improve verb naming abilities in adults with aphasia.
- Trial name
- NCT06776978
- Testing
- Active treatment
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Clinical High Risk for Psychosis
tDCS Coupled With Virtual Rehabilitation for Negative Symptoms in At-Risk Youth
Negative symptoms, which include the loss of motivation, social withdrawal and reduced emotional expression are prominent in youth at clinical high risk (CHR) for psychosis.
- Trial name
- NCT02951208
- Testing
- Active tDCS, Active VR Motivation Training
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- Centre for Addiction and Mental Health
Refractory Epilepsy
Safety and Therapeutic Measures of Tdcs in Patients With Refractory Focal Epilepsy
This is a single site, non-randomized, prospective, open-label, interventional pilot/feasibility study. Patients recruited will have medically-refractory focal neocortical epilepsy, defined on the basis of presence of focal…
- Trial name
- NCT02866240
- Testing
- Cathodal Transcranial Direct Current Stimulation (tDCS).
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Neuroelectrics Corporation
Minimally Conscious State
Closed-loop tDCS in Patients in Minimally Conscious State
This research will test a closed-loop system using EEG-arousal measures (spectral entropy) to define the best moment of the day for application of transcranial direct current stimulation (tDCS) in patients in MCS This study aims…
- Trial name
- NCT03810079
- Testing
- Anodal transcranial direct current stimulation
- Where
- Belgium
- Volunteers
- 16 people
- Sponsor
- University of Liege
Major Depressive Disorder (MDD), SCHIZOPHRENIA 1 (Disorder)
Transcranial Direct Current Stimulation (tDCS) in Different Psychiatric Disorders
The goal of this clinical trial is to evaluate the efficacy and safety of transcranial direct current stimulation (tDCS) in reducing core symptoms of different psychiatric disorders using validated clinical scales.
- Conditions
- Major Depressive Disorder (MDD), SCHIZOPHRENIA 1 (Disorder), Obsessive-Compulsive Disorder, Generalized Anxiety Disorder
- Trial name
- Transcranial (NCT07452835)
- Testing
- tDCS Parameters
- Where
- Egypt
- Volunteers
- 320 people
- Sponsor
- Menoufia University
Disorder of Consciousness
Safety and Efficacy of tDCS in Pediatric DoC
Background: Despite established evidence supporting the use of tDCS in the adult patient with disorders of consciousness, its use in paediatric patients with brain injury is still limited.
- Trial name
- tDCS-DoC-Ped (NCT05929274)
- Testing
- tDCS
- Sponsor
- Giovanna Cristella
Brain Concussion, Mild Traumatic Brain Injury
Neuromodulation and Neuroimaging in Older Children With Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) often causes persistent motor and cognitive deficits in children resulting in functional limitations.
- Conditions
- Brain Concussion, Mild Traumatic Brain Injury, Motor Disorders, Cognitive Impairment
- Trial name
- CI-tDCS (NCT05762796)
- Testing
- tDCS in Youth with mild traumatic brain injury
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Postural Balance
Effects of Transcranial Direct Current Stimulation on Balance of Children With Balance Deficit
Neural control of posture depends on interaction of sensory and motor information from multiple structures, including the primary motor cortex (M1).
- Trial name
- NCT04341220
- Testing
- Transcranial direct current stimulation (tDCS), Balance exercises
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Childhood Onset Dystonias
Transcranial Direct-Current Stimulation in Childhood Dystonia
The investigators hypothesize that transcranial direct current stimulation over the motor cortex will reduce muscle overflow and improve hand function in children with primary or secondary dystonia.
- Trial name
- NCT01460771
- Testing
- TDCS (Transcranial Direct-current Stimulation)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Southern California
Post-stroke Cognitive Impairment
Noninvasive Dual-mode Stimulation Therapy for Neurorehabilitation in Post-stroke Cognitive Impairment
Repetitive transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS) has been used for the modulation of post-stroke cognitive impairment patients' cognitive function by altering the cortical…
- Trial name
- NCT03647319
- Testing
- High-frequency rTMS on left DLPFC+anodal tDCS on right DLPFC, High-frequency rTMS on left DLPFC+cathodal tDCS on right DLPFC
- Where
- South Korea
- Volunteers
- 29 people
- Sponsor
- Samsung Medical Center