Clinical trials: the Severity of Injuries
Head and Neck Cancer, Oral Complications
Sargramostim in Decreasing Mucositis in Patients Receiving Radiation Therapy for Head and Neck Cancer
RATIONALE: Sargramostim may lessen symptoms of mucositis in patients receiving radiation therapy for head and neck cancer. It is not yet known if sargramostim is more effective than no treatment in reducing mucositis caused by…
- Conditions
- Head and Neck Cancer, Oral Complications, Radiation Toxicity
- Trial name
- NCT00008398
- Testing
- sargramostim, quality-of-life assessment, radiation therapy
- Where
- 236 sites in United States, Canada
- Sponsor
- Radiation Therapy Oncology Group
STEMI - ST Elevation Myocardial Infarction, Reperfusion Injury, Myocardial
Combination With Treg Levels and CMR to Assess the Severity and Prognosis of Reperfusion Injury After PPCI in STEMI Patients
This study aims to determine whether combination with regulatory T cell (Treg) levels and cardiac magnetic resonance imaging (CMR) are predictive of the severity of reperfusion injury following myocardial infarction and the…
- Trial name
- TregCMRRS (NCT03939338)
- Testing
- Treg levels and CMR results
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Beijing Friendship Hospital
Head and Neck Cancer, Radiation Toxicity
Parotid-Sparing Intensity-Modulated Radiation Therapy Compared With Conventional Radiation Therapy in Treating Patients With Oropharyngeal or Hypopharyngeal Cancer Who Are at High Risk of Radiation-Induced Xerostomia
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Intensity-modulated radiation therapy delivers thin beams of radiation of different strengths directly to the tumor from many angles.
- Conditions
- Head and Neck Cancer, Radiation Toxicity, Xerostomia
- Trial name
- NCT00081029
- Testing
- management of therapy complications, radiation therapy
- Where
- 9 sites in United Kingdom
- Volunteers
- 84 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Hand Injuries
Cross-cultural Adaptation of the 'Cold Intolerance Severity Score' (CISS) to the Dutch Language.
To report Cold intolerance by the CISS score in medicolegal patients.
- Trial name
- Ciss-DLV (NCT05925907)
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Erasmus Medical Center
Distraction of Bone
Distractor Effect on Pain and Vitality
The aim of the present study was to evaluate the effect of two and four activations /day of periodontal distractor on pain intensity and pulp vitality of maxillary canine.
- Trial name
- NCT05814185
- Testing
- Periodontal distractor
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Rib Fractures, Rib Trauma
Investigation of the Effect of Age and Injury Severity on Short-term Intra-hospital Outcomes After Surgical Stabilized Rib Fractures
The study aims to investigate the effect of surgical stabilisation of rib fractures (SSRF) on clinical outcomes measured during the hospital stay (mortality, days on a mechanical ventilator, intensive care unit and hospital…
- Conditions
- Rib Fractures, Rib Trauma, Rib Fracture Multiple, Thorax; Fracture
- Trial name
- NCT06464302
- Testing
- Surgical stabilisation of rib fractures (SSRF), Non-operative management of rib fractures
- Where
- Germany
- Volunteers
- 1,064 people
- Sponsor
- University Hospital Muenster
Radiation Dermatitis
Dilute Bleach Compresses for Radiation Dermatitis
This study is looking at the safety of applying dilute bleach compresses to patients receiving radiation therapy and the impact of these dilute bleach compresses on the frequency and severity of skin changes that occur during…
- Trial name
- NCT04851522
- Testing
- Di-Dak-Sol, White Petrolatum
- Sponsor
- Dana-Farber Cancer Institute
Wound Healing, Burn
Adult Stem Cell Response to Burn Injury
This study is designed to determine the response of adult stems cells, also referred to as mesenchymal stem cells (MSCs), to tissue injury resulting from thermal burns.
- Trial name
- NCT00609661
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ohio State University
Traumatic Injuries, Prehospital Emergency Care
Study of Pre Hospital Management of Polytrauma Patients by Medical Teams From a Department in the Parisian Region
To study the impact of prehospital management duration by SMUR teams in the Essonne department (91) on early patient mortality (within 24 hours) and to analyze the procedures performed on scene.
- Conditions
- Traumatic Injuries, Prehospital Emergency Care, Early Mortality
- Trial name
- DELTA-91 (NCT07414186)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier Sud Francilien
Heart Failure, Acute Kidney Injury
Viral Illness in Pediatric Critical Care: Incidence Timing & Severity of Associated Heart Dysfunction & Acute Kidney Injury
The purpose of this study is to be able to better describe the incidence, timing and severity of myocardial dysfunction and acute kidney injury (AKI) following a documented respiratory viral illness (RSV, adenovirus…
- Trial name
- MyDAKI-01 (NCT01924663)
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- University of Saskatchewan
Inflammatory Bowel Diseases, Depressive Episode
Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on Health
This study is a large population-based analysis in the United Kingdom (UK) using routine primary care data to investigate the impacts on quality-of-life outcomes and use of healthcare services in people aged 5 - 25 years…
- Conditions
- Inflammatory Bowel Diseases, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorder
- Trial name
- NCT05206734
- Testing
- No specific intervention
- Where
- United Kingdom
- Volunteers
- 19,469 people, healthy volunteers welcome
- Sponsor
- Momentum Data
COVID19, Acute Renal Failure
The Effect of the Severity of COVID-19 Disease on the Incidence of Acute Renal Failure in ICU
Aim of the study is to determinate the frequency of acute renal failure in COVID-19 patients, its relationship with the severity of COVID-19 disease in ICU, and the ability to take precautions against these factors.
- Trial name
- NCT04799600
- Testing
- BRESCİA-COVİD Respiratory Severity Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Bronchopulmonary Dysplasia
Biomarkers and Volumetric Capnography in BPD
The purpose of this study is to assess the association of biomarkers on day 7 of life with the development of bronchopulmonary dysplasia in very preterm infants.
- Trial name
- BPD-2014 (NCT02083562)
- Where
- 2 sites in Switzerland
- Volunteers
- 210 people
- Sponsor
- University Hospital, Basel, Switzerland
Injuries
Impact and Burden of Rugby Injuries in Argentina. A Complete Season Retrospective Multicentric Study.
The aim of this study was to describe the prevalence, incidence and injury load suffered in male amateur rugby players from Argentina during a competitive season in 2019.
- Trial name
- ARugby (NCT04402567)
- Testing
- No Intervention
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Hospital Donación Francisco Santojanni
Nonunion of Fracture of Scaphoid Bone, Fractures, Ununited
Scaphoid Non-union and Low-intensity Pulsed Ultrasound Trial
This is a prospective, double-blind, multicentered, randomized controlled trial to determine the effectiveness of low-intensity pulsed ultrasound in decreasing the time to union of scaphoid non-unions after operative fixation as…
- Trial name
- SNAPU (NCT02383160)
- Testing
- Bioventus Exogen 4000: Low-intensity pulsed ultrasound
- Where
- 6 sites in Canada
- Volunteers
- 154 people
- Sponsor
- University of Calgary
Acute Lung Injury, Acute Respiratory Distress Syndrome
The Role of Circulating Soluble CD74 in Acute Lung Injury
Efforts to identify circulating factors that predict severity of acute lung injury/acute respiratory distress syndrome（ALI/ARDS） patients is unrevealing.
- Trial name
- NCT02201446
- Where
- China
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Acute Coronary Syndrome
Protective Effect of Early High Dose stATins On Cardiovascular and Renal Events in Acute Coronary Syndrome
Registration of all ACS patients (STEMI and NSTEMI) admitted to the cardiology ward and scheduled for early invasive strategy. The aim is to evaluate the protective effects of early (on admission) high-dose high-potency statin…
- Trial name
- PRATO-ACS (NCT04087200)
- Where
- Italy
- Volunteers
- 2,500 people
- Sponsor
- Centro Cardiopatici Toscani
Multiple Trauma
Importance of Forces and Safety Features in Car Crash Multitrauma
The pupose of the study is a prospective evaluation of external and internal factors/causes of importance for the trauma and final outcome experienced by persons inside motor vehicles in serious car accidents.
- Trial name
- NCT00204204
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- University of Oslo
Shaken Baby Syndrome
Predictors of Sequelae Appearance in Shaken Baby Syndrome
This is an observational, prognostic and prospective study. It is about the Prognostic Factors for sequelae in children with a history of Shaken Baby Syndrome (SBS) in the Central region in France.
- Trial name
- FPASSBS (NCT04105673)
- Testing
- Clinical examination and survey
- Sponsor
- University Hospital, Tours
Head Trauma, Polytrauma
Comparative Study for the Validity of Various Severity Scoring System
Scoring systems for use in intensive care unit (ICU) patients have been introduced and developed over the last 30 years. They allow an assessment of the severity of disease and provide an estimate of in-hospital mortality
- Conditions
- Head Trauma, Polytrauma, Pre-Eclampsia, Sepsis
- Trial name
- NCT04683094
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Aswan University Hospital