Clinical trials: in Guinea
Covid19
COVID-19 STAndard of Care in Sub-Saharan Africa
This study was conducted in three African countries on four COVID-19 care centers (CCCs). The CCCs were set up in collaboration with a medical NGO with long experience in recording and monitoring data for cohorts and clinical…
- Trial name
- COVISTA (NCT04885543)
- Where
- 3 sites in Burkina Faso, Guinea
- Volunteers
- 2,495 people
- Sponsor
- Alliance for International Medical Action
African Trypanosomiases, West African; Trypanosomiasis
Diagnostic Tools for Human African Trypanosomiasis Elimination and Clinical Trials: WP2 Passive Case Detection
The study determines the diagnostic performance and cost of rapid diagnostic tests (RDTs) performed on human African trypanosomiasis clinical suspects in peripheral health centres, whether or not followed by serological and/or…
- Conditions
- African Trypanosomiases, West African; Trypanosomiasis, Sleeping Sickness; West African, Trypanosoma Brucei Gambiense; Infection
- Trial name
- DiTECT-WP2 (NCT03356665)
- Testing
- Rapid diagnostic test (RDT), Serological and molecular tests on DBS
- Where
- 3 sites in Côte d’Ivoire, Democratic Republic of the Congo and 1 more
- Volunteers
- 10,700 people
- Sponsor
- Institut de Recherche pour le Developpement
Mother to Child HIV Transmission
HIV Diagnosis and Treatment at Birth for Newborn With High Risk HIV Exposure
Principal objective Assess the operational efficacy of a strategy combining early diagnosis and preventive antiretroviral treatment systematically reinforced from the birth* among infants at high risk of infection with HIV** .
- Trial name
- DIAVINA (NCT03642704)
- Testing
- Reinforced preventive ARV therapy
- Where
- Guinea
- Volunteers
- 56 people
- Sponsor
- ANRS, Emerging Infectious Diseases
Hemorrhagic Fever, Ebola
Emergency Evaluation of Convalescent Plasma for Ebola Viral Disease (EVD) in Guinea
This is an emergency, phase 2/3, open-label, non-randomized, clinical trial that will evaluate Convalescent Plasma (CP) added to standardized supportive care (SC) in patients with confirmed Ebola Virus Disease (EVD).
- Trial name
- Ebola-Tx (NCT02342171)
- Testing
- Convalescent Plasma
- Where
- Guinea
- Volunteers
- 606 people
- Sponsor
- Institute of Tropical Medicine, Belgium
Ebola Virus Infection
Putative Investigational Therapeutics in the Treatment of Patients With Known Ebola Infection
Background: Ebola is a viral infection that can spread quickly and causes life-threatening disease. Right now there is an Ebola outbreak in many countries in West Africa. There are no approved treatments for Ebola.
- Trial name
- NCT02363322
- Testing
- B/Current Standard of Care Plus ZMapp, A/Current Standard of Care Alone
- Where
- 11 sites in United States, Guinea and 2 more
- Volunteers
- 72 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Acute Coronary Syndrome, Heart Failure
A Survey of Hospitalizations in Cardiology Units in Sub-Saharan Africa
FEVRIER study is an observatory of hospitalizations in cardiology units in sub-Saharan Africa.
- Conditions
- Acute Coronary Syndrome, Heart Failure, Syncope, Stroke
- Trial name
- FEVRIER (NCT03231449)
- Testing
- observation of current care
- Where
- 20 sites in Benin, Burkina Faso and 11 more
- Volunteers
- 5,000 people
- Sponsor
- Cardiologie et Développement
Latent Tuberculosis Infection
Rifampin Versus Isoniazid for the Treatment of Latent Tuberculosis Infection in Children (P4v9)
Tuberculosis (TB) is spread by airborne transmission from adults with active contiguous TB to children, especially those living in the same household.
- Trial name
- NCT00170209
- Testing
- Isoniazid, Rifampin
- Where
- 9 sites in Australia, Benin and 5 more
- Volunteers
- 844 people
- Sponsor
- McGill University
Vaginal Fistula
Non-inferiority of Short-term Catheterization Following Fistula Repair Surgery
This facility-based, multi-center randomized controlled trial (RCT) will test the non-inferiority of short-term (7 day) urethral catheterization compared to longer-term (14 day) urethral catheterization in terms of predicting…
- Trial name
- NCT01428830
- Testing
- 7-day catheterization following fistula repair surgery, 14 day catheterization
- Where
- 8 sites in Democratic Republic of the Congo, Ethiopia and 6 more
- Volunteers
- 524 people
- Sponsor
- EngenderHealth
Bacterial Vaginosis, Candidiasis
Study of the Management of Vaginal Discharge in West African Using Single Dose Treatments
This randomised controlled trial aimed to verify whether directly observed single dose treatment (with tinidazole+fluconazole) would be as effective as the longer standard treatments (metronidazole for 7 days, plus vaginal…
- Conditions
- Bacterial Vaginosis, Candidiasis, Vaginitis
- Trial name
- NCT00313131
- Testing
- tinidazole+fluconazole vs metronidazole+clotrimazole
- Where
- 7 sites in Ghana, Guinea and 1 more
- Volunteers
- 1,524 people
- Sponsor
- Université de Sherbrooke