Clinical trials: in Reunion
Hereditary Heart Diseases
Stratification of Arrhythmic Risk and/or Heart Failure Risk in Patients With Hereditary Heart Disease
Sudden cardiac death (SCD) is one of the leading causes of death in developed countries. These deaths (more than 5,000 per year in France) are due to hereditary arrhythmias or cardiomyopathies.
- Trial name
- PREVENT (NCT07257289)
- Testing
- Blood sample
- Where
- 15 sites in France, Martinique and 1 more
- Volunteers
- 1,000 people
- Sponsor
- Nantes University Hospital
Glioblastoma
Diffuse Gliomas in Reunion Island: Establishment of an Epidemiological, Clinical-biological and Socio-anthropological Cohorte
To date, very little data exists on gliomas in the Réunion population, in terms of epidemiology, socio-cultural aspects, clinical or biological factors, and care pathways.
- Trial name
- GLIORUN (NCT07865195)
- Where
- Reunion
- Volunteers
- 214 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Dermatitis
HYPNOsis in the Management of Atopic Dermatitis in Children and Teenagers
Atopic dermatitis (AD) is a chronic inflammatory dermatosis, common in children. It causes pruritus and skin lesions that can have a significant impact on patients' quality of life.
- Trial name
- HypnoDA (NCT05611346)
- Testing
- Hypnosis
- Where
- Reunion
- Volunteers
- 32 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Atopic Dermatitis, Eczema, Atopic
Dupilumab Step-down Strategy to Maintain Remission in Adult and Adolescents Patients With Atopic Dermatitis
The goal of this clinical trial is to compare a step-down strategy of spacing dupilumab injections with a standard maintenance treatment in adolescents and adults with controlled Atopic dermatitis (AD) for at least six months.
- Trial name
- MADULO (NCT05642208)
- Testing
- Dupilumab step-down
- Where
- 32 sites in France, Reunion
- Volunteers
- 256 people
- Sponsor
- Nantes University Hospital
Running, Motivation for Physical Activity
Study of the Psychological, Physiological and Biomechanical Responses to Trail Running in a Hot, Humid Environment
The determinants of trail performance have been extensively studied, and the results have revealed the significant influence of physiological, psychological and biomechanical parameters.
- Conditions
- Running, Motivation for Physical Activity, Sport Physiology
- Trial name
- RP2B-Trail (NCT07831109)
- Testing
- Trail running of 28km and 2580m vertical drop
- Where
- Reunion
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Pediatric Tumor
Use of Virtual Reality in Pain Management in Pediatric Oncology
DOREVI is a monocentric randomized controlled study that will evaluate the efficacy of virtual reality helmets for pain prevention during invasive care on 78 oncologic pediatric patients.
- Trial name
- DOREVI (NCT05592132)
- Testing
- Virtual reality headset
- Where
- Reunion
- Volunteers
- 74 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Leptospirosis
Chronic Post-leptospirosis Manifestations in Reunion
Leptospirosis is a zoonosis caused by spirochetes, pathogenic bacteria of the genus Leptospira. It is transmitted to humans through mucocutaneous lesions by contact with water or soil contaminated by the urine of animal…
- Trial name
- LEPTONIC (NCT05436756)
- Testing
- Biological sampling and collection
- Where
- 4 sites in France, Reunion
- Volunteers
- 198 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Contraception Behavior
SAPLAI : Assessing the faiSAbility of a Peer-to-peer Contraceptive Education Program on Social Networks Aimed at 15- to 19-year-old High School Students in GuAdeloupe and La RéunIon
The goal of this clinical trial is to evaluate the feasibility of a contraception education program delivered by peers via social networks to high school students.
- Trial name
- SAPLAI (NCT06943209)
- Testing
- Creation of a contraception education program and post on social networks for high school students, Education program, Survey and questionnaires
- Where
- 2 sites in Guadeloupe, Reunion
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Cystic Fibrosis
Pathogenicity of Species of the Achromobacter Genus in Patients From Reunion Island With Cystic Fibrosis
The pathogenicity of Achromobacter bacteria is not yet well established, but studies show a decline in respiratory function and an increase in mortality associated with chronic colonisation, making it possible to classify the…
- Trial name
- ACHROMO-MUCO (NCT06371261)
- Testing
- Biological analyses
- Where
- 2 sites in Reunion
- Volunteers
- 17 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Esophageal Atresia
Long Term Outcome of Easophageal Atresia : Transmics Profiles in Adolescence
Oesophageal atresia (OAEA), a malformation of the oesophagus present from birth, is characterized by the interruption of the continuity of the oesophagus, which then ends in a cul-de-sac.
- Trial name
- TransEAsome (NCT05995171)
- Testing
- Questionnaire
- Where
- 33 sites in France, Martinique and 1 more
- Volunteers
- 300 people
- Sponsor
- University Hospital, Lille
Very Preterm Birth
EPIPAGE2 Cohort Study Follow up at Five and a Half Years
Epipage 2 (epidemiologic study on small-for-gestational-age children) is a nationwide study implemented to improve our knowledge of the outcome of preterm children in France.
- Trial name
- EPIPAGE2 (NCT03078439)
- Testing
- Medical and neuropsychological assessments
- Where
- 98 sites in France, French Guiana and 2 more
- Volunteers
- 3,404 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Appendicitis
Same Day Ambulatory Appendectomy (SAMBA)
The potential benefit of outpatient care for this common digestive emergency is considerable, both for the patients themselves and for the public health system: 1.
- Trial name
- SAMBA (NCT05691348)
- Testing
- Ambulatory appendectomy, Conventional appendectomy
- Where
- 33 sites in France, Reunion
- Volunteers
- 1,400 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Idiopathic Nephrotic Syndrome
A National Prospective Cohort of Patients With Idiopathic Nephrotic Syndrome Beginning in Childhood.
Pediatric idiopathic nephrotic syndrome (INS) is a rare disease for which the optimal therapeutic strategy has not yet been defined.
- Trial name
- PIN'SNP (NCT04207580)
- Testing
- Inclusion and follow up of pediatric patients with an idiopathic nephrotic syndrome,
- Where
- 48 sites in France, Reunion
- Volunteers
- 1,180 people
- Sponsor
- University Hospital, Limoges
Leg Length Inequality
Study to Assess the Pain, Satisfaction, and Quality of Life of Patients With FITBONE® Lengthening Nail
This study is a prospective observational non-interventional multi-centre cohort study of patients, 12 years or older, initiating a lower limb lengthening procedure with FITBONE and who have a length discrepancy of 30mm or more…
- Trial name
- FitForFrance (NCT06156384)
- Testing
- FITBONE® Lengthening Nail
- Where
- 6 sites in France, Reunion
- Volunteers
- 45 people
- Sponsor
- Orthofix s.r.l.
Long QT Syndrome, Brugada Syndrome
Impact on Risk Stratification of Overlap Syndrome Phenotype in Patients With E1784K Mutation in SCN5A
In patients expressing the SCN5A-E1784K mutation (Glu1784Lys), cardiovascular risk is difficult to define as the stratification of these patients is challenging.
- Conditions
- Long QT Syndrome, Brugada Syndrome, Cardiac Conduction System Disease, Arrhythmias, Cardiac
- Trial name
- RISKOVER (NCT05274646)
- Where
- Reunion
- Volunteers
- 47 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Sport Injury
Epidemiology and Risk Factors for Injuries in Beach Tennis Players
Beach tennis, a fast-growing sport since its creation in Italy in the 1970s, has rapidly gained in popularity, particularly in La Réunion sisland since 2000.
- Trial name
- EPITRAUMA-BT (NCT06701409)
- Where
- Reunion
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Language Disorders in Children, Learning; Developmental Disorder
Impact of Teacher Training and the Introduction of Early Adjustments on the Developmental Trajectory of Children at Risk of SLLD in Pre-school.
The high incidence of neurodevelopmental disorders, including specific language and learning disorders, and their profund impact on the schooling of the children concerned remains a major public health concern.
- Trial name
- PRISME-TSLA (NCT06062147)
- Testing
- Teacher training
- Where
- Reunion
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Predisposition, Genetic, Cancer Childhood
EXOme Rare Cancers in Children (EXOCARE)
Other than high-dose radiation and previous chemotherapy, few strong risk factors have been identified as causes of childhood cancer.
- Conditions
- Predisposition, Genetic, Cancer Childhood, Development Delay
- Trial name
- EXOCARE (NCT03472807)
- Testing
- Collection of blood sample or saliva, Collection of a tumor sample taken before the participation of the patient in study, Collection of blood sample if tumor sample is not available
- Where
- 27 sites in France, Reunion
- Volunteers
- 169 people
- Sponsor
- University Hospital, Angers
Single Embryo Transfer, Fertilization in Vitro
Advantages of Early Intrauterine Transfer of "Blank" Culture Medium Prior to 1st or 2nd Transfer of Thawed Embryo(s).
Despite technical advances in Medically Assisted Reproduction (AMP), the success of fertility treatments is sometimes limited by embryo implantation failure.
- Trial name
- TRABLAN (NCT06177613)
- Testing
- Blank culture transfer
- Where
- 7 sites in France, Reunion
- Volunteers
- 1,154 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Sickle Cell Disease
ESCORT-HU Extension: European Sickle Cell Disease Cohort - Hydroxyurea - Extension Study
As safety information pertaining to the long-term use of HU remains incomplete in spite of the first safety study (ESCORT-HU), an extension of the latter is proposed.
- Trial name
- NCT04707235
- Testing
- Hydroxycarbamide
- Where
- 87 sites in France, French Guiana and 6 more
- Volunteers
- 2,093 people
- Sponsor
- Theravia