Clinical trials: in Reunion
Melanoma
The Impact of a Prevention Program on Sun Risks in Primary School in Tropical French Region
Sun exposure during childhood can cause the development of skin cancer in later years, in particular melanoma, which is the most lethal.The worldwide incidence of melanoma is on the rise, with nearly 290,000 new cases diagnosed…
- Trial name
- PRESOLRE (NCT05367180)
- Testing
- MISOLRE prevention program on sun risks, "Vivre avec le Soleil" prevention program on sun risks, Sun protection equipment
- Where
- Reunion
- Volunteers
- 1,452 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Neoplasms
Cancer Survival in Reunion Island , 1998-2008 (SUCRE)
Cancer survival is important to determine prognostic of patients and evaluate care and prevention health strategies. Sucre is the first study to describe cancer survival in Reunion Island.
- Trial name
- SUCRE (NCT02900287)
- Where
- Reunion
- Volunteers
- 18,000 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Chikungunya Virus Infection
Consequences of a Maternal-fetal Chikungunya Virus Infection
Chikungunya is an infectious disease caused by an alphavirus transmitted by the Aedes mosquitoes which has known a worldwide expansion since its re-emergence in 2004.
- Trial name
- CHIK13+ (NCT04909411)
- Testing
- OPHTHALMOLOGICAL ASSESSMENT, NEUROPSYCHOLOGICAL ASSESSMENT
- Where
- Reunion
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Leptospirosis
Study of the Innate Immune Response to the Acute Phase of Human Leptospirosis - IMMUNOLEPTO
The research hypothesis is based on a suspected strong involvement of the immune system in the genesis of serious manifestations of the disease (hepatitis, renal failure, thrombocytopenia, intra-alveolar hemorrhage).
- Trial name
- IMMUNOLEPTO (NCT05413720)
- Testing
- two additional blood samples specific to research
- Where
- 4 sites in Reunion
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Fetal Alcohol Spectrum Disorders, Hyperactivity Disorder
Monitoring and Evaluation of a Cognitive Behavioral Therapy Program Focused on Attention and Emotion Regulation for Children With Fetal Alcohol Spectrum Disorder
This is a multi-center, prospective, randomized, open-label, controlled trial with two parallel arms and blinded endpoint assessment.
- Conditions
- Fetal Alcohol Spectrum Disorders, Hyperactivity Disorder, Attention Deficit
- Trial name
- SEPAGE (NCT05273918)
- Testing
- cognitivo-comportmental therapy, body mediation
- Where
- 3 sites in France, Reunion
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Acute Myocarditis
Hospital Registry of Acute Myocarditis: Evolution of the Proportion of Positive SARS-COV-2 (COVID19) Cases
To date, the effects of SARS-Cov-2 (Covid-19) on the myocardium and the role it plays in the evolution towards an acute myocarditis are badly understood.
- Trial name
- MYOCOVID (NCT04375748)
- Testing
- Performing routine care (clinical and paraclinical tests), Examinations for the research:
- Where
- 65 sites in France, Martinique and 2 more
- Volunteers
- 756 people
- Sponsor
- University Hospital, Toulouse
Leptin Receptor Deficiency Obesity
Setmelanotide for the Treatment of Leptin Receptor (LEPR) Deficiency Obesity
To demonstrate statistically significant and clinically meaningful effects of setmelanotide on percent body weight change in participants with LEPR deficiency obesity due to rare bi-allelic or loss-of function mutations at the…
- Trial name
- NCT03287960
- Testing
- Setmelanotide
- Where
- 6 sites in Canada, France and 4 more
- Volunteers
- 15 people
- Sponsor
- Rhythm Pharmaceuticals, Inc.
Fever, Dengue
Cohort of Patients Infected by an Arbovirus
There are hundred of arbovirus which have been shown to cause disease in humans. Their most common clinical symptoms are algo-eruptive (dengue, chikungunya, zika), hemorrhagic fever (dengue, yellow fever, Crimean-Congo…
- Conditions
- Fever, Dengue, Chikungunya, Zika Virus
- Trial name
- CARBO (NCT01099852)
- Testing
- biological sample collection, Quality of life Questionnaire EuroQol®, Health Assessment Questionnaire - MDHAQ and RAPID3
- Where
- 8 sites in France, French Guiana and 3 more
- Volunteers
- 1,377 people
- Sponsor
- University Hospital Center of Martinique
Hearing Loss, Cochlear
Evaluation of the Effect of a Spatial Localization Training Program on Auditory Comprehension
Hearing comprehension under complex listening conditions is considered to be the central complaint of everyday life for patients with cochlear implants. Localization is one of the cues for listening comprehension.
- Trial name
- CAudiBruit (NCT05237180)
- Testing
- spatial localisation training
- Where
- Reunion
- Volunteers
- 12 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Intensive Care Units, Pediatric
Therapeutic Follow-up of Antibiotics in Pediatric Intensive Care
Currently, recommendations for antibiotic testing (ATS) in adult intensive care have been published. The 2018 SFAR and the Abdul- Aziz et al expert conference recommend routine testing for β-lactams, aminoglycosides, linezolid…
- Trial name
- STAR-P (NCT05354635)
- Testing
- Antibiotics Dosing
- Where
- Reunion
- Volunteers
- 280 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Kidney Failure, Acute
Modalities of Renal Replacement Therapy in Pediatric Acute Kidney Injury
Limited prospective data is available to compare morbidity and mortality between renal replacement modalities in pediatric acute renal failure.
- Trial name
- EPURE (NCT01569698)
- Testing
- acute extra renal replacement therapy
- Where
- 19 sites in Canada, France and 1 more
- Volunteers
- 310 people
- Sponsor
- Rennes University Hospital
Suicide Attempt
Suicide Prevention Algorithm in the French Overseas Territories
In France, suicide behaviours are a major public health concern that triggered the creation in 2013 of a National Observatory of Suicide.
- Trial name
- APSOM (NCT03427190)
- Testing
- APSOM vs Control
- Where
- 9 sites in French Guiana, Guadeloupe and 2 more
- Volunteers
- 259 people
- Sponsor
- University Hospital Center of Martinique
Pregnancy Loss, Infant Death
In-utero Death and Birth Mortality in Reunion Island
Infant mortality is still relevant despite the improvement and the accessibility of hospital care. Premature birth are two fold higher than in metropolitan France.
- Trial name
- RAMIR (NCT03354832)
- Testing
- Foetal death, New-born death, Birth control for foetal death
- Where
- Reunion
- Volunteers
- 45 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Unverricht-Lundborg Disease
Brivaracetam as add-on Treatment of Unverricht-Lundborg Disease in Adolescents and Adults
The study will compare the efficacy and safety of brivaracetam with placebo in patients with Unverricht-Lundborg disease.
- Trial name
- NCT00357669
- Testing
- Brivaracetam 25 mg, Brivaracetam 50 mg
- Where
- 13 sites in Finland, France and 5 more
- Volunteers
- 50 people
- Sponsor
- UCB Pharma SA