Clinical trials: in Syria
Dental Esthetic, Dental Care for Children, Dental Crowns
Prefabricated CAD/CAM PEEK Crowns For Primary Molars Restoration
This Split-mouth randomized clinical trial aims to evaluate CAD/CAM prefabricated Polyether ether ketone crowns for primary molars restoration after pulpotomy compared to Stainless steel crowns Over follow-up periods of 3, 6, and…
- Trial name
- NCT07618871
- Testing
- Prefabricated CAD/CAM PEEK with 0.2 mm thickness, Prefabricated CAD/CAM PEEK with 0.4 mm thickness, CAD/CAM-fabricated PEEK Crowns
- Where
- Syria
- Volunteers
- 60 people
- Sponsor
- Arab International University
Effectiveness of Anesthesia Using Electronic Syringe in Children in the Context of Endotopy Treatment
Effectiveness of Intraligament vs IANB Anesthesia in Children Using Electronic Syringe
This randomized clinical study aims to evaluate the efficacy and pain response of two local anesthesia techniques in pediatric dental treatment using an electronic syringe: ligament anesthesia and inferior alveolar nerve block…
- Trial name
- NCT07095946
- Testing
- Electronic Syringe Intraligament Technique, Electronic syringe IANB Technique
- Where
- Syria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Latakia University
Reversible Pulpitis
TheraCal PT vs. Formocresol in Primary Molar Pulpotomies
This prospective, randomized, parallel-group clinical trial evaluated the 12-month clinical and radiographic success rates of TheraCal PT versus formocresol in primary molar vital pulpotomies among 50 children aged 5 to 8 years.
- Trial name
- NCT07864181
- Testing
- Dual cured resin modified
- Where
- Syria
- Volunteers
- 50 people
- Sponsor
- Hama University
CLASS II DIVISION 1 MALOCCLUSION
Pain and Comfort During Functional Orthodontic Treatment With Laser or Ultrasounic Waves
Pain, discomfort, and functional limitations are common during functional orthodontic treatment and may affect appliance acceptance, compliance, and treatment satisfaction.
- Trial name
- NCT07852559
- Testing
- Activator + LIPUS, Activator + LLLT
- Where
- Syria
- Volunteers
- 40 people
- Sponsor
- Damascus University
Malocclusion, Class II Malocclusion
Treatment of Mild Class II Malocclusion in Adult Patients With Clear Aligners Versus Fixed Multibracket Therapy
Patient with class ii division 1 malocclusion who have mild increased overjet will be treated in this study. The efficacy of clear aligners in the treatment of Class II division 1 Malocclusion Using Intermaxillary Elastics will…
- Trial name
- malocclusion (NCT05684510)
- Testing
- clear aligners, traditional treatment Fixed appliances with class II elastics.
- Where
- Syria
- Volunteers
- 24 people
- Sponsor
- Hama University
Malocclusion, Angle Class II
Treatment of Skeletal Class II Malocclusion With Modified Twin-Block Appliance With Clear Plates
Patients with skeletal class II malocclusion who have a retracted lower jaw will be treated in this study. The efficacy of clear Plates in the treatment of Skeletal Class II Malocclusion will be assessed.
- Trial name
- NCT05950581
- Testing
- Modified Twin-Block Appliance with Clear Plates., Traditional Twin-Block appliance
- Where
- Syria
- Volunteers
- 32 people
- Sponsor
- Hama University
Permanent Molars, Dental Caries
Hall Technique vs Conventional Crown Restoration in Permanent Molars: Split-Mouth Trial in Children
The aim of this study is to compare the clinical and radiographic success of stainless steel crowns placed using the Hall Technique versus the conventional method in the restoration of permanent first molars in children, and to…
- Conditions
- Permanent Molars, Dental Caries, Tooth Decay, Permanent First Molar Caries
- Trial name
- HTCC-SM (NCT07186673)
- Testing
- Stainless steel crown placement using Hall Technique, Stainless steel crown placement using conventional method
- Where
- 2 sites in Syria
- Volunteers
- 10 people
- Sponsor
- Latakia University
Molar Incisor Hypomineralisation
Etch-bleach-seal Technique in Managing Opacities Related MIH Using Icon®
Objectives: to compare aesthetic effectiveness of resin infiltration with/without using sodium hypochlorite in managing opacities of MIH on incisors, and to compare parent's satisfaction with results of both application…
- Trial name
- NCT07162077
- Testing
- Sodium hypochlorite 5.25%, ICON resin infiltration Material group in vivo
- Where
- Syria
- Volunteers
- 15 people
- Sponsor
- Latakia University
Anxiety, Dental
The Impact of Valerian and Chamomile on Children's Anxiety in the Dental Clinic
This randomized controlled clinical trial aims to evaluate and compare the effectiveness of chamomile extract and valerian extract in reducing dental anxiety in healthy pediatric patients aged 6 to 10 years undergoing tooth…
- Trial name
- NCT07515612
- Testing
- Valerian extract, Chamomile extract
- Where
- Syria
- Volunteers
- 78 people
- Sponsor
- Damascus University
Heart Surgery, Ischemic Heart Disease
Efficacy of Carbohydrate Loading in Diabetic Type 2 Patients Undergoing CABG Surgery on CPB
Enhanced recovery after surgery protocols aim to optimize perioperative care and improve surgical outcomes. Preoperative carbohydrate loading has demonstrated benefits in reducing insulin resistance and improving patient…
- Trial name
- CLDM-CABG (NCT06951308)
- Testing
- Carbohydrate loading before surgery
- Where
- Syria
- Volunteers
- 50 people
- Sponsor
- Damascus University
Distraction, Behavior Management
Video-Enhanced Tell-Show-Do for Managing Dental Anxiety in Children
This study is the first of its kind to examine the effect of integrating the real oral environment with a video that supports the expressions used during the Tell-Show-Do technique (such as "we will see the cavity," "the cavity…
- Trial name
- NCT07632547
- Testing
- Behavioral Treatment
- Where
- Syria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Damascus University
Dental Anxiety, Pain Management
Effectiveness of Virtual Reality Technique on Children
Studying the effect of using virtual reality technique in managing pain, anxiety, and vital signs among pediatric dental patients.
- Conditions
- Dental Anxiety, Pain Management, Pediatric Dentistry
- Trial name
- NCT07722221
- Testing
- Conventional, Virtual reality
- Where
- Syria
- Volunteers
- 64 people
- Sponsor
- Latakia University
Skeletal Class II Malocclusion
Modified Versus Clear Twin Block for Skeletal Class II Malocclusion
This study aims to evaluate the effectiveness of a modified Twin Block appliance compared to a conventional clear Twin Block appliance in the treatment of skeletal Class II malocclusion caused by mandibular retrusion in growing…
- Trial name
- MTB-CTB (NCT07608406)
- Testing
- Modified Twin Block Appliance, Conventional Clear Twin Block Appliance
- Where
- Syria
- Volunteers
- 40 people
- Sponsor
- University of Aleppo
Malocclusion of Anterior Teeth, Malocclusion; Displaced Teeth
Effects of Three Orthodontic Archwire Protocols on Root and Bone Changes
This randomized controlled clinical trial compares the effects of three orthodontic archwire protocols used during the alignment phase on anterior tooth roots and the supporting alveolar bone.
- Trial name
- NCT07688655
- Testing
- Square-shaped cross-sectional archwire, Rectangular-shaped cross-sectional archwire, Traditional sequence of archwires
- Where
- Syria
- Volunteers
- 53 people
- Sponsor
- Damascus University
Orthodontic Appliance Complication
Effect of Local Subperiosteal Zoledronic Acid Injection on the Survival of Orthodontic Miniscrews
Background: Orthodontic miniscrews are widely used as temporary anchorage devices; however, failure remains a clinical concern. Bisphosphonates may enhance bone stability, but evidence on their local application is limited.
- Trial name
- NCT07546058
- Testing
- Zoledronic Acid, Normal saline (0.9% sodium chloride)
- Where
- Syria
- Volunteers
- 68 people
- Sponsor
- Latakia University
Hyperbilirubinemia, Neonatal Indirect
The Efficacy of Ursodeoxycholic Acid (UDCA) as Adjuvant Therapy to Phototherapy in the Management of Neonatal Indirect Hyperbilirubinemia
This is a prospective, open-label, randomized controlled trial conducted at Lattakia University Hospital (Tishreen University), aiming to evaluate the efficacy of Ursodeoxycholic Acid (UDCA) as an adjuvant to triple phototherapy…
- Trial name
- UDCA-Neo (NCT07110987)
- Testing
- Phototherapy, ursodeoxycholic acid (UDCA)
- Where
- Syria
- Volunteers
- 70 people
- Sponsor
- Tishreen University Hospital
Internal Mammary Artery Syndrome, Vasodilation
Effect of Topically-applied Milrinone or Nitroglycerin on Internal Mammary Artery Free Flow
Forty-six consecutive patients undergoing elective primary coronary artery bypass grafting were enrolled. After the left IMA was harvested, free flow was measured under controlled hemodynamic conditions before any intervention…
- Trial name
- NCT06301880
- Testing
- The topical application of a vasodilator on the LIMA graft
- Where
- Syria
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Damascus University
Dental Anxiety, Dental Pain
Clinical Outcomes of Mandibular Primary Molar Extraction Using Physics Forceps in Children
Tooth extraction is a common procedure and often associated with pain, fear, and discomfort especially in pediatric patients, which may lead to a negative attitude toward the dental.
- Conditions
- Dental Anxiety, Dental Pain, Dental Extraction, Primary Molar Tooth
- Trial name
- NCT07366788
- Testing
- ARM 1 Physics forceps (40 Participant), ARM 2 conventional forceps (40 Participant)
- Where
- Syria
- Volunteers
- 80 people
- Sponsor
- Damascus University
Myocardial Injury, Cardiac Surgery
Comparison of Changes in Intra-myocardial Amino Acids During Use of Calafiore and Modified Del Nido Cardioplegia
The aim of the present study was to investigate intra-operative changes in markers of myocardial injury and myocardial intracellular amino acids during ischemia and reperfusion, comparing two methods of myocardial protection…
- Conditions
- Myocardial Injury, Cardiac Surgery, Myocardial Protection
- Trial name
- NCT06287372
- Testing
- Cardioplegic solution
- Where
- Syria
- Volunteers
- 20 people
- Sponsor
- Damascus University
Malocclusion, Angle Class II, Division 1
Evaluating Laser and Piezocision vs. Piezocision Alone on Root Resorption and Gingival Health During Tooth Retraction
This trial aims to determine whether using a special laser (low-level laser therapy, or LLLT) in combination with a minor surgical procedure (piezocision) can safely accelerate orthodontic treatment.
- Trial name
- NCT07442825
- Testing
- Flapless Corticotomy (Piezocision), Level Laser Therapy (LLLT), Traditional treatment
- Where
- Syria
- Volunteers
- 66 people
- Sponsor
- Damascus University