Clinical trials: Atorvastatin
Lupus Erythematosus, Systemic
Atherosclerosis Prevention in Pediatric Lupus Erythematosus (APPLE)
The purpose of this study is: 1. To assess the efficacy of a lipid-lowering agent (atorvastatin) on the development of atherosclerosis that predisposes children with SLE to cardiovascular events in adulthood. 2.
- Trial name
- NCT00065806
- Testing
- Atorvastatin
- Where
- United States
- Volunteers
- 221 people
- Sponsor
- Laura Schanberg
HIV Infections, Hyperlipidemia
IMPAACT P1063: Safety and Effectiveness of Atorvastatin in HIV Infected Children and Adolescents With Hyperlipidemia
Treatment of HIV with combination antiretroviral regimens frequently results in the suppression of HIV viral load, significant immune recovery, and delayed disease progression.
- Trial name
- NCT00663234
- Testing
- Atorvastatin
- Where
- 11 sites in United States
- Volunteers
- 28 people
- Sponsor
- International Maternal Pediatric Adolescent AIDS Clinical Trials Group
Focal Segmental Glomerulosclerosis
Novel Therapies for Resistant FSGS (FONTII): Phase II Clinical Trial
This project will test whether adalimumab,and/or galactose can safely reduce proteinuria (abnormal amounts of protein in the urine) and protect kidney function better than standard treatment for patients with focal segmental…
- Trial name
- FONTII (NCT00814255)
- Testing
- Adalimumab, Lisinopril, losartan, and atorvastatin, galactose
- Where
- 18 sites in United States, Canada
- Volunteers
- 32 people
- Sponsor
- NYU Langone Health
Type II Diabetes Mellitus, Dyslipidemia
Follow-On Study of Pitavastatin Versus Atorvastatin in Patients With Type II Diabetes Mellitus and Combined Dyslipidemia
This is a sixteen-week double-blind active-controlled follow-on and 28-week single-blind extension study for patients who participated in study NK-104-305.
- Trial name
- NCT00344370
- Testing
- Pitavastatin, Atorvastatin
- Where
- 35 sites in Denmark, Germany and 4 more
- Volunteers
- 214 people
- Sponsor
- Kowa Research Europe
Angioplasty, Transluminal, Percutaneous Coronary
Effect of Atorvastatin Administration Before Primary Percutaneous Coronary Intervention
The purpose of this study to determine whether statin pretreatment decrease myocardial infarct size in patients with acute myocardial infarction undergoing primary percutaneous coronary intervention.
- Trial name
- NCT00610870
- Testing
- atorvastatin
- Where
- South Korea
- Volunteers
- 173 people
- Sponsor
- Samsung Medical Center
Systemic Lupus Erythematosus
An Open Labeled Pilot Study of Atorvastatin in Systemic Lupus Erythematosus
The aim of this study is to to determine whether atorvastatin 40mg per day is effective in the treatment of SLE.
- Trial name
- NCT00432354
- Testing
- atorvastatin
- Where
- 2 sites in Taiwan
- Volunteers
- 40 people
- Sponsor
- Buddhist Tzu Chi General Hospital
End-Stage Renal Disease
Pediatric Kidney Transplant Without Calcineurin Inhibitors
The purpose of this study is to see the effect of using drugs other than calcineurin inhibitors to improve the rate of kidney transplant failure. Kidney transplantation can help children with end-stage kidney disease.
- Trial name
- NCT00023231
- Testing
- Daclizumab, Methylprednisolone/prednisone, Mycophenolate mofetil
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Aggressive Non-Hodgkin Lymphoma, Blasts Under 5 Percent of Bone Marrow Nucleated Cells
Donor Atorvastatin Treatment in Preventing Severe Acute GVHD After Nonmyeloablative Peripheral Blood Stem Cell Transplant in Patients With Hematological Malignancies
This phase II trial studies how well donor atorvastatin treatment works in preventing severe graft-versus-host disease (GVHD) after nonmyeloablative peripheral blood stem cell (PBSC) transplant in patients with hematological…
- Conditions
- Aggressive Non-Hodgkin Lymphoma, Blasts Under 5 Percent of Bone Marrow Nucleated Cells, Chronic Lymphocytic Leukemia, Loss of Chromosome 17p
- Trial name
- NCT01527045
- Testing
- Atorvastatin Calcium, Cyclosporine, Fludarabine Phosphate
- Where
- 2 sites in United States
- Volunteers
- 47 people
- Sponsor
- Fred Hutchinson Cancer Center
Collateral Circulation, Large-artery Occlusion
Study of Collateral Circulation in Patients With Symptomatic Intracranial Anterior Circulation Occlusion
Intracranial artery stenosis is the leading cause of stroke onset or recurrence in Asian. Multiple studies have shown that anterior circulation is most common in intracranial artery stenosis, especially the middle cerebral artery…
- Conditions
- Collateral Circulation, Large-artery Occlusion, Cerebral Infarction
- Trial name
- NCT04091412
- Testing
- Butylphthalide Soft Capsules
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Hebei Medical University
Coronary Artery Disease
Atorvastatin Pre-Treatment Influences the Risk of Percutaneous Coronary Intervention Study
This study investigates potential protective effect of atorvastatin pre-treatment in patient with stable coronary artery disease undergoing percutaneous coronary intervention (PCI).
- Trial name
- TIPS (NCT00469326)
- Testing
- Atorvastatin
- Where
- Czechia
- Volunteers
- 200 people
- Sponsor
- University Hospital, Motol
Ischemic Stroke, Large-Artery Atherosclerosis (Embolus/Thrombosis)
Study of Predictive Factors Related to Prognosis of Patients With Ischemic Stroke Due to Large-artery Atherosclerosis
This is a single-center prospective cohort study of predictive factors related to prognosis of ischemic stroke due to large-artery atherosclerosis.
- Trial name
- NCT04847752
- Testing
- carotid artery stenting, carotid endarterectomy, Aspirin
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Tongji Hospital
Chronic Subdural Hematoma
Low Intracranial Pressure Treatment Strategies for Chronic Subdural Hematoma Patients
The proportion of the elderly population is increasing rapidly. Chronic subdural hematoma has become the most common cause of surgery in neurosurgery for elderly patients. The standard treatment for cSDH is mostly surgery.
- Trial name
- CSDH-LP (NCT04607447)
- Testing
- low intracranial pressure strategy treatment, Atorvastatin plus Dexamethasone
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Huashan Hospital
Hypercholesterolemia
A Clinical Trial Study to Evaluate Efficacy and Safety of Atorvastatin in Korean Patients With Hypercholesterolemia
The purpose of this study is to compare the efficacy and safety of atorvastatin generic product with reference drug.
- Trial name
- NCT01081548
- Testing
- atorvastatin
- Where
- South Korea
- Volunteers
- 17 people
- Sponsor
- Yonsei University
ST Elevation Myocardial Infarction
Effect of Upstream Treatment With High Intensity Statin on the Outcomes of STMI Patients Treated With PPCI
Effect of upstream treatment with high intensity statin on the outcome of ST segment elevation myocardial infarction patients treated with primary percutaneous coronary intervention
- Trial name
- NCT04754789
- Testing
- Atorvastatin, Aspirin
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Assiut University
Type 1 Diabetes
Atorvastatin in New Onset Type 1 Diabetes Mellitus (T1DM)
The goal of this application is to evaluate the safety and efficacy of atorvastatin as a potential treatment to preserve beta cell function in children and young adults with newly diagnosed type 1 diabetes (T1DM).
- Trial name
- TIDM (NCT00529191)
- Testing
- Atorvastatin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Children's Hospital of Philadelphia
Coronary Artery Disease, Coronary Angioplasty
Atorvastatin Pre-Treatment Influences the Risk of Percutaneous Coronary Intervention (PCI) Study 2
This study investigates potential protective effect of atorvastatin pre-treatment in patient with stable coronary artery disease undergoing percutaneous coronary intervention (PCI) on chronic statin therapy.
- Trial name
- TIPS-2 (NCT01058057)
- Testing
- atorvastatin
- Where
- Czechia
- Volunteers
- 200 people
- Sponsor
- University Hospital, Motol
Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus
Pediatric Atorvastatin in Diabetes Intervention Trial (PADIT)
The purpose of this study is to determine if Atorvastatin can improve blood vessel stiffness and blood vessel function in children 10-18 years old with Type 1 and Type 2 diabetes.
- Trial name
- NCT00130481
- Testing
- Atorvastatin 20 mg daily for 3 months
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Florida
HIV Infections, Drug Interactions
Drug-drug Interactions Between Antiretroviral Drugs and Cardiovascular Drugs in Elderly Patients
Ageing is characterized by physiological changes, which can impact drug pharmacokinetics and thereby cause drug-drug interactions.
- Conditions
- HIV Infections, Drug Interactions, Cardiovascular Diseases
- Trial name
- NCT03515772
- Testing
- Co-administration of darunavir with a cardiovascular drug
- Where
- 2 sites in Switzerland
- Volunteers
- 21 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Cardiovascular Diseases
Atorvastatin Versus Simvastatin In The Prevention Of Coronary Heart Disease (CHD) In Patients With Known CHD
To investigate whether a long-term strategy to lower LDL cholesterol with atorvastatin as much as possible will improve prognosis in CHD patients compared with a strategy reflecting current best clinical practice with simvastatin.
- Trial name
- IDEAL (NCT00159835)
- Testing
- atorvastatin, simvastatin
- Where
- 194 sites in Denmark, Finland and 4 more
- Volunteers
- 8,600 people
- Sponsor
- Pfizer
Angina Pectoris, Variant
Efficacy Study of Atorvastatin to Treat Variant Angina
The objective of this study is to evaluate effect of statin treatment for vasospastic angina.
- Trial name
- ESAVA (NCT00620204)
- Testing
- atorvastatin
- Where
- South Korea
- Volunteers
- 136 people
- Sponsor
- Samsung Medical Center