Clinical trials: Azithromycin
Cystic Fibrosis
Testing the Effect of Adding Chronic Oral Azithromycin to Inhaled Tobramycin in People With Cystic Fibrosis (CF)
This is a study to examine the effect of combining chronic oral azithromycin with inhaled tobramycin in adolescent and adult subjects with cystic fibrosis who are chronically infected with P. aeruginosa.
- Trial name
- TEACH (NCT02677701)
- Testing
- azithromycin, inhaled tobramycin
- Where
- 39 sites in United States
- Volunteers
- 119 people
- Sponsor
- Seattle Children's Hospital
Mortality, Child Health
Azithromycin for Child Survival in Niger: Delivery Trial
This cluster-randomized trial aims to compare the impact of different delivery approaches to azithromycin distribution on coverage, costs, and feasibility outcomes.
- Conditions
- Mortality, Child Health, Implementation
- Trial name
- AVENIR (NCT04774991)
- Testing
- Azithromycin for Oral Suspension
- Where
- Niger
- Volunteers
- 10,925 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Mycobacterium Avium-intracellulare Infection, HIV Infections
A Randomized, Double-Blind, Comparative Study of Azithromycin Versus Clarithromycin in Combination With Ethambutol for the Treatment of Disseminated Mycobacterium Avium Complex (MAC) Infection in AIDs Patients
To evaluate the efficacy and safety of two different doses of azithromycin in combination with ethambutol for the treatment of patients with Mycobacterium avium complex (MAC) infection, and to determine whether an…
- Trial name
- NCT00002140
- Testing
- Ethambutol hydrochloride, Clarithromycin, Azithromycin
- Where
- 24 sites in United States
- Sponsor
- Pfizer
Mycobacterium Avium-Intracellulare Infection, HIV Infections
An Open-Label Study of the Use of Azithromycin in Patients With Symptomatic Disseminated Mycobacterium Avium-Intracellulare Complex (MAC) Infection Failing Current Therapy
To evaluate the efficacy and safety of azithromycin given chronically for the treatment of Mycobacterium avium (MAC) bacteremia in patients failing or intolerant of current available MAC therapy.
- Trial name
- NCT00002089
- Testing
- Azithromycin
- Where
- United States
- Sponsor
- Pfizer
Pneumonia, Diarrhea
Azithromycin to Prevent Post-discharge Morbidity and Mortality in Kenyan Children
Children hospitalized with severe illness in sub-Saharan Africa are at high risk of morbidity and mortality following discharge from hospital.
- Conditions
- Pneumonia, Diarrhea, Malaria, Co-infection
- Trial name
- Toto Bora (NCT02414399)
- Testing
- Azithromycin
- Where
- Kenya
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- University of Washington
Acne Vulgaris
Vitamin A and Azithromycin for Acne Vulgaris
Patients seen with acne lesions not having responded to existing treatments will be offered a placebo or a topical preparation consisting of Vitamin A USP with or without Azithromycin for a duration of 4-6 months USP for the…
- Trial name
- NCT03090048
- Testing
- Vitamin A, Azithromycin
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Manchanda Medical Clinic
COVID-19
Effectiveness of Remedesvir in COVID-19 Patients Presenting at Mayo Hospital Lahore
Currently, several drugs including Remdesivir, hydroxychloroquine, chloroquine, ritonavir+lopinavir, Tocilizumab, Arbidol and interferon are under randomised controlled trials (RCTs) for efficacy and/or safety evaluations in…
- Trial name
- NCT04871633
- Testing
- Remdesivir, Conventional
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- King Edward Medical University
Bronchopulmonary Dysplasia, Premature
THE EFFECT OF NEBULIZED AZITHROMYCIN AS THERAPY FOR BRONCHOPULMONARY DYSPLASIA
The aim of the study is to determine the effectiveness of nebulized azithromycin therapy in prevention of BPD in very low birth weight preterm infants when compared with placebo.
- Conditions
- Bronchopulmonary Dysplasia, Premature, Ventilation, Mechanical
- Trial name
- NCT06584474
- Testing
- Azithromycin neubilization, Lung ultrasound
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Alexandria University
Pneumonia
Randomised Evaluation of COVID-19 Therapy
RECOVERY is a randomised trial of treatments to prevent death in patients hospitalised with pneumonia. The treatments being investigated are: COVID-19: Lopinavir-Ritonavir, Hydroxychloroquine, Corticosteroids, Azithromycin…
- Trial name
- RECOVERY (NCT04381936)
- Testing
- Lopinavir-Ritonavir, Corticosteroid, Hydroxychloroquine
- Where
- 16 sites in Belgium, Estonia and 14 more
- Volunteers
- 70,000 people
- Sponsor
- University of Oxford
Bacterial Conjunctivitis
Evaluation of Clinical and Microbial Efficacy and Safety of AzaSite Compared to Vehicle for Bacterial Conjunctivitis (C-01-401-003)
The purpose of this study is to evaluate the clinical and microbial efficacy and safety of AzaSite compared to vehicle for bacterial conjunctivitis.
- Trial name
- NCT00105534
- Testing
- AzaSite, Vehicle
- Where
- 32 sites in United States
- Volunteers
- 685 people
- Sponsor
- Merck Sharp & Dohme LLC
Cystic Fibrosis
Effect of Azithromycin on Lung Function in 6-18 Year-olds With Cystic Fibrosis (CF) Not Infected With P. Aeruginosa
This is a study to examine the safety, effect on lung function, and frequency of symptoms relating to cystic fibrosis during 24 weeks of treatment with the antibiotic azithromycin in 6-18 year-olds with CF who are not infected…
- Trial name
- NCT00431964
- Testing
- azithromycin 250 mg tablets
- Where
- 40 sites in United States, Canada
- Volunteers
- 263 people
- Sponsor
- CF Therapeutics Development Network Coordinating Center
Retinal Detachment, Achilles Tendon
A Study of Fluoroquinolones Exposure and Collagen-Related Serious Adverse Events
The purpose of this study is to evaluate whether there is an increased risk of achilles tendon rupture (ATR), retinal detachment (RD) or aortic aneurysm and dissection (AAD) following exposure to fluoroquinolone (FQ) or other…
- Conditions
- Retinal Detachment, Achilles Tendon, Aneurysm, Dissecting
- Trial name
- NCT03479736
- Testing
- Oral Fluoroquinolones (FQ), Other Antibiotics, Febrile Illness Not Treated with Antibiotics Will be Analyzed as an Exposure
- Where
- United States
- Volunteers
- 117,911 people
- Sponsor
- Janssen Research & Development, LLC
Ureaplasma Infections
Trial of Intravenous Azithromycin to Eradicate Ureaplasma Respiratory Tract Infection in Preterm Infants
The purpose of this study is to determine whether intravenous azithromycin is effective in eradicating Ureaplasma respiratory tract infection in preterm infants born at 24 to 28 weeks gestation.
- Trial name
- AZIPIII (NCT01778634)
- Testing
- Azithromycin
- Where
- 7 sites in United States
- Volunteers
- 121 people
- Sponsor
- University of Maryland, Baltimore
Toxoplasmosis, Cerebral, HIV Infections
A Study of Azithromycin Plus Pyrimethamine in the Treatment of a Brain Infection in Patients With AIDS
To evaluate the effectiveness and toxicity of oral azithromycin and pyrimethamine as acute therapy for toxoplasmic encephalitis in AIDS patients.
- Trial name
- NCT00000966
- Testing
- Azithromycin, Pyrimethamine, Leucovorin calcium
- Where
- 11 sites in United States
- Volunteers
- 45 people
- Sponsor
- Pfizer
Dysentery, Shigella, Shigellosis
Ciprofloxacin Versus Azithromycin for Children Hospitalised With Dysentery
The purpose of this study is to assess the efficacy of 3 days of azithromycin (AZI) compared to 3 days of ciprofloxacin (CIP) (standard-of-care) for the treatment of children hospitalised with dysentery in Ho Chi Minh City.
- Conditions
- Dysentery, Shigella, Shigellosis, Diarrhea
- Trial name
- CIPAZ (NCT03854929)
- Testing
- Ciprofloxacin, Azithromycin
- Where
- Vietnam
- Volunteers
- 364 people
- Sponsor
- Oxford University Clinical Research Unit, Vietnam
Enteric Fever
Meropenem vs Azithromycin Efficacy in Case XDR Enteric Fever
1. Primary Objective: o To evaluate the efficacy of intravenous azithromycin compared with meropenem in the treatment of extensively drug-resistant (XDR) enteric fever. 2.
- Trial name
- NCT07314281
- Testing
- Azithromycin, Meropenem Injection
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Indus Hospital and Health Network
Respiratory Syncytial Virus, Bronchiolitis
Azithromycin to Prevent Wheezing Following Severe RSV Bronchiolitis-II
The main objective of the APW-RSV II clinical trial is to evaluate if the addition of azithromycin to routine bronchiolitis care, among infants hospitalized with RSV bronchiolitis, reduces the occurrence of recurrent wheeze…
- Trial name
- APW-RSV-II (NCT02911935)
- Testing
- Oral azithromycin
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Washington University School of Medicine
Pneumonia, Community-Acquired
A Trial Of Azithromycin SR For The Treatment Of Mild To Moderate Community Acquired Pneumonia In Japanese Adults
To evaluate the clinical efficacy and safety in patients with mild or moderate community-acquired pneumonia receiving a dose of 2 g of azithromycin in the SR formulation.
- Trial name
- NCT00360295
- Testing
- Azithromycin SR
- Where
- 54 sites in Japan
- Volunteers
- 153 people
- Sponsor
- Pfizer
Mycobacterium Avium-intracellulare Infection, HIV Infections
A Study to Evaluate the Effects of Azithromycin on MAC Disease Prevention in HIV-Positive Patients
This study is designed to find out whether HIV-positive patients whose immune systems have improved after receiving anti-HIV treatment should take azithromycin to prevent Mycobacterium avium complex (MAC) disease.
- Trial name
- NCT00000947
- Testing
- Azithromycin
- Where
- 19 sites in United States
- Volunteers
- 850 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Covid19
Effectiveness of Ivermectin and Doxycycline on COVID-19 Patients
A randomized controlled trial on using Ivermectin and doxycycline to treat mild-moderate outpatients, severe, and critical inpatients of Coronavirus disease 19 (COVID-19) along with standard of care.
- Trial name
- NCT04591600
- Testing
- Ivermectin and Doxycyline, Standard of care
- Where
- Iraq
- Volunteers
- 140 people
- Sponsor
- Alkarkh Health Directorate-Baghdad