Clinical trials: Best Practice
Cystic Fibrosis, Quality of Life
Pragmatic Implementation Trial of a CF Primary Palliative Care Intervention
Five Cystic Fibrosis (CF) centers, key stakeholders, and a palliative care institute have collaborated to create a novel primary palliative care intervention for patients with CF, "Improving Life with CF: A Primary Palliative…
- Trial name
- NCT04923880
- Testing
- Implementation of Primary Palliative Care Intervention in CF Centers
- Where
- 5 sites in United States
- Volunteers
- 643 people
- Sponsor
- Massachusetts General Hospital
Stress Disorders, Traumatic, Psychological Trauma
Effect Study of SMART Treatment for Youth
The goal of this clinical trial is to learn if Sensory motor arousal regulation treatment (SMART) works better than treatment as usual (TAU) to treat youth 7-17 years with complex trauma histories and self-regulation…
- Conditions
- Stress Disorders, Traumatic, Psychological Trauma, Sexual Trauma, Stress Disorders, Post-Traumatic; Mental Disorders
- Trial name
- UTVID (NCT07200713)
- Testing
- Treatment as usual (TAU), Sensory motor arousal regulation treatment (SMART)
- Where
- 4 sites in Norway
- Volunteers
- 120 people
- Sponsor
- Vestre Viken Hospital Trust
Bronchiectasis
Evaluation of Medical and Nursing Management for Bronchiectasis
The purpose of this research is to retrospectively evaluate current clinical care of Bronchiectasis (non-cystic fibrosis [CF]) in adults from a multidisciplinary management perspective.
- Trial name
- NCT03550417
- Volunteers
- 65 people
- Sponsor
- The Queen Elizabeth Hospital
Preterm Birth, Pregnancy
An Electronic Medical Record Alert of Progesterone
Progesterone can be given to women at risk for preterm birth, and is advocated by many guidelines as progesterone has been shown to markedly decrease preterm birth, death in newborns, and disability.
- Trial name
- NCT03219489
- Testing
- Electronic medical record alert
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- McMaster University
Maternal Health, Gender
The Effectiveness of Multi-pronged Interventions to Improve Institutional Delivery in South Ethiopia
This study aims to improve the health and safety of mothers during pregnancy and childbirth by working closely with their husbands.
- Trial name
- NCT07133321
- Testing
- Husband Group Health education., Helping Mothers Survive + RMC
- Where
- Ethiopia
- Volunteers
- 1,680 people
- Sponsor
- Prof Yves Jacquemyn
Chronic Low Back Pain
Virtual Reality Therapy for Chronic Low Back Pain
This study will test the efficacy of an evidence-based virtual reality (VR) therapy program as a non-pharmacological supplement for the management of chronic lower back pain.
- Trial name
- NCT04409353
- Testing
- Distraction-Based VR, Skills-Based VR, Activity Tracker
- Where
- United States
- Volunteers
- 413 people
- Sponsor
- Cedars-Sinai Medical Center
Attention Deficit/Hyperactivity Disorder, Inattention
Pilot Testing PREschooler Care, Community Resources, Advocacy, Referral, Education (PRE-CARE)
The goal of this proposed study is to pilot test a novel treatment model (PRE-CARE) addressing unmet social needs for families of preschool-age children with Attention Deficit/Hyperactivity Disorder (ADHD) symptoms.
- Trial name
- PRE-CARE (NCT04999982)
- Testing
- Screening, Resource Packet, Resource Navigation
- Where
- 2 sites in United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Non-technical Skills
Observation of Non-technical Skills in the Pre-hospital Care in the Czech Republic
The aim of the study is to find out if the Emergency Medical Services (EMS) crews are using the non-technical skills (e.g. communication, decision making, situational awareness etc.) in the real practice and how well they use…
- Trial name
- NTS (NCT04503369)
- Testing
- Non-technical skills
- Where
- 3 sites in Czechia
- Volunteers
- 359 people, healthy volunteers welcome
- Sponsor
- David Peran
ADHD
Classroom Behavior Support (CBS) Project
The goal of the study is to conduct a randomized clinical trial to evaluate the impact of the Classroom Behavior Support Program (CBS; a multi-component, individually-tailored teacher consultation program) on teachers' classroom…
- Trial name
- CBS (NCT05137327)
- Testing
- Classroom Behavior Support (CBS) Condition, Standard Problem Solving Consultation
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Ohio University
Bipolar Disorder
Evaluating the Effectiveness of Family-Focused Psychoeducation in Treating Adolescents With Bipolar Disorder
This study will evaluate the effectiveness of family-focused psychoeducational treatment along with medication in treating adolescents with bipolar I disorder.
- Trial name
- NCT00571402
- Testing
- Family-focused therapy for adolescents, Enhanced care
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- University of California, Los Angeles
Dating Violence, Alcohol Drinking
Evaluation of PRYSHM for LGBTQIA2S+ Youth
The overarching goal of the proposed project is to develop an innovative, online synchronous DV and AU prevention curriculum created specifically for SGMY (ages 15 to 18); conduct a pilot randomized controlled trial to assess its…
- Trial name
- PRYSHM (NCT05521906)
- Testing
- Promoting Resilient Youth with Strong Hearts and Minds (PRYSHM)
- Where
- United States
- Volunteers
- 314 people
- Sponsor
- University of Nebraska Lincoln
Children With Complex Chronic Conditions
Garnering Effective Telehealth 2 Help Optimize Multidisciplinary Team Engagement
The purpose of this study is to determine the effectiveness of the GET2HOME Intervention bundle.
- Trial name
- GET2HOME (NCT05568355)
- Testing
- GET2HOME Intervention
- Where
- United States
- Volunteers
- 638 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Patient Safety
Openness and Learning Joint Commission: Using Patient Experience for Improvement Following a Patient Safety Event
The focus of our work is openness, learning and person-centred involvement following patient safety incidents in health care. We will explore patients, carers and relatives' perspectives on what is important to them, what…
- Trial name
- NCT04897087
- Testing
- patient safety event
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people
- Sponsor
- NHS Education for Scotland
Technology
Effectiveness of a Smart Hearing Aid on Improving Psychosocial Well-being in Elderly
The study has 2 primary research questions, 4 secondary research questions, and 2 auxiliary research questions targeting elderly with hearing impairment. The research questions are: Primary study questions: 1.
- Trial name
- NCT05772949
- Testing
- Experimental group intervention, Wait-list control group intervention
- Where
- 3 sites in Hong Kong
- Volunteers
- 33 people
- Sponsor
- The University of Hong Kong
Labor Stage, First, Prolonged Labor
Maternal Maneuvers During Prolonged Labor
This pilot, randomized control trial will test whether or not a specific circuit of position changes improves maternal outcomes in cases of prolonged labor.
- Trial name
- CIRCUIT (NCT06636149)
- Testing
- Circuit of maternal position changes during labor
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Washington University School of Medicine
Autism Spectrum Disorder
A Trial of Project ImPACT in Early Intervention
Our pilot study will address a number of pressing questions, including: Can community clinicians successfully coach parents of children with ASD in evidence-based practice to achieve positive outcomes for their children and…
- Trial name
- NCT04729127
- Testing
- Project ImPACT
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- University of Pennsylvania
Cerebral Hypoxia, Severe Traumatic Brain Injury
Prioritization of Cerebral Deoxygenation in Severe Traumatic Brain Injury and Mortality Benefit.
Severe traumatic brain injury with a decrease in cerebral oximetry is associated with multiple impaired systemic microcirculations, more morbidities, and a higher mortality rate.
- Trial name
- NCT06306950
- Testing
- Near infrared spectroscopy neuromonitor to prevent cerebral desaturation
- Where
- Thailand
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Phramongkutklao College of Medicine and Hospital
Influenza
The INFLUENTIAL Trial- Evaluation of National Inpatient Influenza Vaccination Program
This study plans to learn more about whether a stakeholder-informed, standardized inpatient vaccination program will increase influenza vaccination rates of hospitalized children across US pediatric health systems.
- Trial name
- Influential (NCT05832307)
- Testing
- Existing Influenza Vaccination Practices, Standardized inpatient influenza vaccination program
- Where
- 2 sites in United States
- Volunteers
- 22,000 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Implicit Bias
Virtual Implicit Bias Reduction and Neutralization Training (VIBRANT)
Healthcare providers' implicit bias has been identified as a contributor to longstanding health inequities via negative impacts on the patient-clinician relationship and biased delivery of high-quality evidence-based practices…
- Trial name
- VIBRANT (NCT05970991)
- Testing
- Brief Online Training (BOLT) for measurement-based care (MBC), Virtual Implicit Bias Reduction and Neutralization Training (VIBRANT), Live Post-Training Consultation
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Washington
Temporomandibular Disorder, Myalgia
Treatment of Temporomandibular Disorders in Children and Adolsecents
Children and adolescents are treated with routine treatment approaches for adults and one of the most commonly used treatments are occlusal appliances.
- Conditions
- Temporomandibular Disorder, Myalgia, Arthralgia of TMJ
- Trial name
- TMD/PED (NCT03849534)
- Testing
- Soft occlusal appliance, Jaw exercises, Counseling
- Where
- Sweden
- Sponsor
- Karolinska Institutet