Clinical trials: Doxycycline
Necrotic Primary Molars
Lesion Sterilization And Tissue Repair Versus Zinc Oxide And Eugenol For Treatment of Necrotic Primary Molars
The aim of this study is to evaluate the clinical and radiographic success of Lesion Sterilization And Tissue Repair [ LSTR] antibiotic paste versus Zinc Oxide and Eugenol pulpectomy in the treatment of non-vital primary molars.
- Trial name
- LSTR (NCT05448937)
- Testing
- Lesion sterilization and tissue repair, zinc oxide and eugenol pulpectomy
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Multiple Erythema Migrans
Antibiotic Treatment of Multiple Erythema Migrans
The purpose of this study is to compare the efficacy and safety of 15-day ceftriaxone versus 15-day doxycycline treatment in patients with multiple erythema migrans.
- Trial name
- NCT01163994
- Testing
- ceftriaxone, doxycycline, erythema migrans patients treated with doxycycline
- Where
- Slovenia
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Sexually Transmitted Infections (Not HIV or Hepatitis), HIV Infections
Sexual Health Access at Retail Pharmacies: Advancing Pharmacy-based Delivery of Primary STI and HIV Prevention for Cisgender Women
This proposed 3-arm randomized study will compare different pharmacy based approaches that include HIV prevention medication (PrEP and PEP), routine STI testing, and preventive antibiotic (doxycycline) for STIs.
- Trial name
- SHARP (NCT07361926)
- Testing
- doxy-PEP, Serial STI testing, HIV PEP/PrEP
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- University of Washington
Acne Vulgaris
Clinical Trial to Compare Oral Isotretinoin to Standard of Care in Moderate Acne Skin of Color Patients
In Dermatology, assessment of people of color remains underrepresented in RCTs (<10%) and guidelines. Acne affects around 9% of the population worldwide and negatively affects quality of life and self-esteem with anxiety…
- Trial name
- ETHNIC (NCT06447480)
- Testing
- ISOtretinoin 5 MG, Topical cream
- Where
- 19 sites in France, French Guiana
- Volunteers
- 420 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Atypical Pneumonia
Treatment and Vaccine Development of Mycoplasma Pneumoniae
A randomized clinical trial comparing treatment effectiveness of azithromycin and doxycycline for pediatric Mycoplasma pneumonia.
- Trial name
- NCT03911440
- Testing
- Doxycycline, Azithromycin
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Leishmaniasis, Cutaneous
Intralesional Voriconazole, or Intralesional Cryotherapy, or Oral Doxycycline in the Treatment of Cutaneous Leishmaniasis
Leishmaniasis is a vector-borne disease caused by obligate, intracellular protozoa of the genus Leishmania and transmitted by phlebotomine sandflies.
- Trial name
- NCT05708625
- Testing
- Intralesional Sodium stibogluconate, Intralesional Cryotherapy, Intralesional Voriconazole
- Where
- Libya
- Volunteers
- 136 people
- Sponsor
- Zagazig University
Chronic Periodontitis
Efficacy of Subgingivally Delivered Doxycycline Plus Ketoprofen Gel as an Adjunct to Non-surgical Periodontal Treatment
Objectives: The aim of the present clinical study was to evaluate the efficacy of doxycyline 3% plus ketoprofen 2.5% as an adjunct to scaling and root planing in the treatment of chronic periodontitis(early-modearte).
- Trial name
- NCT02538224
- Testing
- 2.5%ketoprofen gel + 3 % doxycycline, :2.5%ketoprofen gel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Propionibacterium
Does Preoperative Administration of Oral Doxycycline Decrease the Colonization Rate of Propionibacterium Acnes in the Dermis of the Shoulder?
The purpose of this study is to evaluate the ability of oral doxycycline to decrease the colonization of Propionibacterium acnes in the dermis of the shoulder.
- Trial name
- NCT02688738
- Testing
- Doxycycline
- Sponsor
- Rothman Institute Orthopaedics
Acne Vulgaris
Weekly Isotretinoin vs Tetracycline for Moderate Acne
In the effort to find better treatments for Moderate Acne, which often relies on long-term antibiotic use, researchers are exploring alternative options.
- Trial name
- NCT06225570
- Testing
- Isotretinoin, Tetracycline
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Suspected Early Lyme Neuroborreliosis
Doxycycline and Ceftriaxone in Suspected Early Lyme Neuroborreliosis
The investigators will compare doxycycline and ceftriaxone in treatment of patients with suspected early Lyme neuroborreliosis and normal CSF cell count.
- Trial name
- NCT00942006
- Testing
- doxycycline, ceftriaxone
- Where
- Slovenia
- Volunteers
- 200 people
- Sponsor
- University Medical Centre Ljubljana
Relapsing Fever, Tick-borne, Jarisch Herxheimer Reaction
Post Exposure Treatment With Doxycycline for the Prevention of Relapsing Fever
Abstract Background Tick-Borne Relapsing Fever (TBRF) is an acute febrile illness. In Israel, TBRF is caused by Borrelia persica and is transmitted by Ornithodoros tholozani ticks.
- Trial name
- NCT00237016
- Testing
- doxycycline treatment
- Where
- Israel
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Medical Corps, Israel Defense Force
Posterior Blepharitis
Oral Azithromycin Versus Doxycycline in Posterior Blepharitis
One hundred patients with the diagnosis of posterior blepharitis based on history taking and proper physical examinations by two experienced ophthalmologists will include in the study.
- Trial name
- NCT01783860
- Testing
- Azithromycin, Doxycycline
- Where
- Iran
- Volunteers
- 100 people
- Sponsor
- Tehran University of Medical Sciences
Lactating Women on Select DOI, Breastfed Infants of Mothers on Select DOI
Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants
Over half of women in the US who are breastfeeding their infants take prescription drugs. You are being asked to participate in this study because you are breastfeeding your infant and are currently taking, as part of your…
- Trial name
- NCT03511118
- Testing
- Tranexamic acid (TXA), labetalol, metformin
- Where
- 22 sites in United States, Canada
- Volunteers
- 1,600 people
- Sponsor
- Duke University
Infertility, Female, Pelvic Inflammatory Disease
Effect of Prophylactic Antibiotics for Hysterosalpingography on Post Procedure Morbidity
The study will be a parallel randomised trial. There are two groups. The first group will be given prophylactic antibiotics before a procedure (hysterosalpingography) and the second group will be given a placebo(multivitamin).
- Trial name
- NCT04234945
- Testing
- Doxycycline Capsule, Multivitamins W/Iron Tab
- Where
- Nigeria
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Ahmadu Bello University Teaching Hospital
Seizures
Doxycycline for the Treatment of Nodding Syndrome
Nodding syndrome (NS) is a devastating neurologic disorder affecting thousands of children in Africa. A number of toxic, nutritional, infectious, para-infectious and environmental causes have been studied but the only consistent…
- Trial name
- NCT02850913
- Testing
- Doxycycline
- Where
- Uganda
- Volunteers
- 230 people
- Sponsor
- Makerere University
Acne
Comparative Efficacy and Safety of Benzoyl Peroxide Used in Combination With Clindamycin vs. Benzoyl Peroxide Used in Combination With Clindamycin and Doxycycline in the Treatment of Moderate Acne
To compare the efficacy and safety of Benzoyl peroxide used in combination with clindamycin vs. Benzoyl peroxide used in combination with clindamycin and doxycycline in the treatment of moderate acne
- Trial name
- NCT00837213
- Testing
- Benzoyl peroxide with clindamycin, Benzoyl peroxide with clindamycin and doxycycline
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- Stiefel, a GSK Company
Urethritis
NGU: Doxycycline (Plus or Minus Tinidazole) Versus Azithromycin (Plus or Minus Tinidazole)
This study will look at the safety, effectiveness, and tolerability of combination medications for the initial treatment of non-gonococcal urethritis (NGU). NGU is inflammation of the tube that carries urine from the bladder.
- Trial name
- NCT00322465
- Testing
- Doxycycline, Tinidazole, Azithromycin
- Where
- 4 sites in United States
- Volunteers
- 305 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Acneiform Drug Eruption, Acneiform Eruptions
Isotretinoin vs. Doxycycline for Acneiform Rash in Patients Receiving Drugs That Target the MAPK Pathway
A phase 2 study testing the efficacy of isotretinoin versus doxycycline in treating participants who develop a acneiform rash caused by standard of care, tumor-directed therapies targeting the mitogenactivated protein kinase…
- Trial name
- PNOC039 (NCT07629167)
- Testing
- Isotretinoin, Doxycycline, Blood specimen collection
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Francisco
Acne Vulgaris
Comparing Sarecycline and Doxycycline Effects on the Skin and Gut Bacteria in Acne.
This study is being done to help better understand how the gut and skin bacteria of the body change when people with acne are treated with Sarecycline or Doxycycline.
- Trial name
- NCT07544251
- Testing
- Sarecycline, Doxycycline
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Pneumonia, Mycoplasma
Treatment of Macrolide-resistant Mycoplasma Pneumoniae
A randomized clinical trial comparing treatment effectiveness of azithromycin and doxycycline for pediatric Mycoplasma pneumonia.
- Trial name
- NCT03530319
- Testing
- Doxycycline, Azithromycin
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital