Clinical trials: Escitalopram
Lactating Women on Select DOI, Breastfed Infants of Mothers on Select DOI
Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants
Over half of women in the US who are breastfeeding their infants take prescription drugs. You are being asked to participate in this study because you are breastfeeding your infant and are currently taking, as part of your…
- Trial name
- NCT03511118
- Testing
- Tranexamic acid (TXA), labetalol, metformin
- Where
- 22 sites in United States, Canada
- Volunteers
- 1,600 people
- Sponsor
- Duke University
Depression - Major Depressive Disorder, Depressive Episodes
TDM-Guided Treatment With SSRIs in Hospitalized Adults and Children
Depression in childhood and adolescence is a serious and increasing public-health problem associated with profound short- and long-term consequences, including impaired social and educational functioning, increased risk of…
- Trial name
- NCT07478796
- Testing
- Fluoxetine, Escitalopram, Sertralin
- Where
- Poland
- Volunteers
- 180 people
- Sponsor
- Poznan University of Medical Sciences
Autism Spectrum Disorder
Neuroimaging of Escitalopram in Autism Spectrum Disorder
The goal of this clinical trial is to evaluate the acute effects of escitalopram (Lexapro®) on select brain networks during task-based functional magnetic resonance imaging (fMRI) in adolescent individuals with autism spectrum…
- Trial name
- NCT06826326
- Testing
- Escitalopram 10mg
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Kathryn Unruh
Anxiety, Depressive Symptoms
Acute and Long-Term Antidepressant Treatment Success in Adolescents With Anxiety (AtLAS-A)
Acute, double-blind, adaptively randomized treatment with duloxetine or escitalopram, followed by open-label naturalistic follow-up.
- Trial name
- AtLAS-A (NCT04245436)
- Testing
- Duloxetine, Escitalopram
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Cincinnati
Anxiety
Pharmacogenetically-guided Escitalopram Treatment for Pediatric Anxiety: Aiming to Improve Safety and Efficacy (PrEcISE)
This double-blind, 12-week study will consist include132 anxious youth who are randomized (1:1) to standard or pharmacogenetically-guided escitalopram dosing.
- Trial name
- PrEcISE (NCT04623099)
- Testing
- Escitalopram
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Depressive Disorder, Adolescent
Development and Application of Comprehensive Intervention Techniques for Adolescent Depression
In order to realize the early identification, risk warning and comprehensive intervention of adolescent depression, this project carried out research on the diagnosis platform of adolescent depression, the construction of suicide…
- Trial name
- NCT05945342
- Testing
- Escitalopram, Interpersonal Psychotherapy for Adolescent, Escitalopram combined with psychotherapy
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Adolescent Depression
Efficacy and Safety of Bifidobacterium Combined With High-frequency Transcranial Magnetic Stimulation in the Treatment of Adolescent Depression
A total of 100 patients with adolescent depression who were admitted to our hospital between March 2022 and October 2022 were selected.
- Trial name
- NCT06325605
- Testing
- Bifidobacterium, High-frequency rTMS, Escitalopram Oxalate
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Zhen-Hong Hu
Bipolar Disorder
Longitudinal Comparative Effectiveness of Bipolar Disorder Therapies
The objective of this retrospective observational study is to compare commonly prescribed bipolar disorder medications for their impact on: (1) hospitalization; (2) suicide attempts and self-harm; and (3) risk of drug-induced…
- Trial name
- NCT02893371
- Testing
- Lithium Carbonate, Lamotrigine, Valproic Acid
- Where
- United States
- Volunteers
- 1,037,352 people
- Sponsor
- University of New Mexico
Depression, Anxiety
Mechanism of Antidepressant-Related Dysfunctional Arousal in High-Risk Youth
A 16-week double blind, placebo-controlled investigation of escitalopram in adolescents with depression and/or anxiety with a family history of Bipolar Disorder.
- Conditions
- Depression, Anxiety, Bipolar Disorder
- Trial name
- NCT02553161
- Testing
- Escitalopram, Cognitive behavioral Psychotherapy
- Where
- 2 sites in United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Anxiety Disorders,Generalized Anxiety Disorder
A Study of Escitalopram in the Treatment of Children and Adolescents With Generalized Anxiety Disorder
This is a study in minors (7 to 17 years old) diagnosed with generalized anxiety disorder (GAD) and evaluated using standard questionnaires as having at least moderate severity of GAD.
- Trial name
- NCT03924323
- Testing
- Escitalopram
- Where
- 39 sites in United States
- Volunteers
- 273 people
- Sponsor
- AbbVie
Major Depressive Disorder, Bipolar Disorder, Mixed
Chinese Longitudinal and Systematic Study of Bioplar Disorder
Affective disorders (mainly including major depressive disorder and bipolar disorder) are common, chronic and highly disabling mental disorders, which lack of objective biological markers.
- Conditions
- Major Depressive Disorder, Bipolar Disorder, Mixed, Affective; Disorder, Organic
- Trial name
- CLASS-BD (NCT05480150)
- Testing
- Escitalopram Oxalate Tablets, Quetiapine Fumarate Tablets, Lurasidone
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Anxiety
Neurofunctional Predictors of Escitalopram Treatment Response in Adolescents With Anxiety
Neurofunctional Predictors of Escitalopram Treatment Response in Adolescents with Anxiety. To determine the effects of escitalopram on functional activation patterns during a Continuous Performance Task with Emotional and Neutral…
- Trial name
- FiESTAA (NCT02818751)
- Testing
- Escitalopram
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Depression, Suicide, Attempted
Treatment of Adolescent Suicide Attempters (TASA)
The purpose of this study is to compare the effects of three types of treatments for depressed teenagers who have attempted suicide.
- Trial name
- NCT00080158
- Testing
- fluoxetine, sertraline, citalopram
- Where
- 6 sites in United States
- Volunteers
- 120 people
- Sponsor
- New York State Psychiatric Institute
Addiction
Establishment of Cessation Therapy by Clinical Trials for Subjects With Betel-quid Dependence and Oral Pre-cancer
No medication existed for BQ dependence. No clinical trials existed for the drug therapy. Previous study showed that BQ possessed the antidepressant effect via pathway of monoamine oxidase A (MAO-A).
- Trial name
- NCT03010761
- Testing
- escitalopram, Moclobemide
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Depression, Adolescent
Biomarkers of Antidepressant Response and Suicidal Events in Depressed Youth
The aims of this study are to (1) identify inflammatory/neurotrophic and neurodevelopmental markers that predict antidepressant response and suicidal risk in depressed youth and (2) predict their treatment response and the…
- Trial name
- NCT03547219
- Testing
- Escitalopram
- Where
- South Korea
- Volunteers
- 152 people
- Sponsor
- Seoul National University
Major Depressive Disorder, Anxiety Disorders
Escitalopram in the Treatment of Adolescents With Major Depressive Disorder or Anxiety Disorders
Escitalopram has been approved by FDA in the treatment of adolescents with major depressive disorder since March 2009. To date, there are only 3 clinical trials assessing the effect and validity of escitalopram on major…
- Trial name
- NCT03122158
- Testing
- Escitalopram
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Erzurum Regional Training & Research Hospital
Depression, Acute Kidney Injury
Serotonin-norepinephrine Reuptake Inhibitors and Acute Kidney Injury
The purpose of this study is to determine if there is an excess risk of acute kidney injury (AKI) with Serotonin-norepinephrine reuptake inhibitors (SNRIs) as compared to Selective serotonin reuptake inhibitors (SSRIs), two…
- Trial name
- SNRI-AKI (NCT02320240)
- Testing
- Duloxetine, Venlafaxine, Desvenlafaxine
- Where
- Canada
- Volunteers
- 3,255,526 people
- Sponsor
- Canadian Network for Observational Drug Effect Studies, CNODES
Obsessive-Compulsive Disorder
Treatment of Obsessive Compulsive Disorder in Children
This study will determine whether cognitive behavioral therapy delivered by either psychologists or psychiatrists can improve the effectiveness of serotonin reuptake inhibitor treatment in children with obsessive compulsive…
- Trial name
- NCT00074815
- Testing
- Serotonin reuptake inhibitors management, Cognitive behavioral therapy by a psychologist, Instructional cognitive behavioral therapy by a psychiatrist
- Where
- 3 sites in United States
- Volunteers
- 124 people
- Sponsor
- Duke University
PMS
Escitalopram for Premenstrual Syndrome (PMS) in Teens: A Pilot Study
The purpose of this pilot study is to determine the efficacy and safety of escitalopram administered premenstrually (day 14 through day 2 of the menstrual cycle) for severe PMS in young women ages 15-19 years.
- Trial name
- NCT00523705
- Testing
- escitalopram
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Pennsylvania
Major Depressive Disorder
Safety Study of Escitalopram in Children 7 to 11 Years of Age With Major Depressive Disorder
This study will evaluate the long-term safety and tolerability of escitalopram (Lexapro) in children 7 to 11 years of age with major depressive disorder (MDD).
- Trial name
- NCT01198795
- Testing
- Escitalopram
- Where
- 16 sites in United States
- Volunteers
- 162 people
- Sponsor
- Forest Laboratories