Clinical trials: Maltodextrin
Cerebral Palsy, Chronic Constipation
Synbiotic, Prebiotics and Probiotics in Children With Cerebral Palsy and Constipation
Randomized double blind controlled clinical trial. Participants will be enrolled at the New Civil Hospital of Guadalajara "Dr. Juan I. Menchaca" during the period from May 2017 to July 2018, from six to 59 months of either sex.
- Trial name
- NCT03117322
- Testing
- agave inulin, Lactobacillus reuteri DSM 17938, maltodextrin
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Andrea Garcia Contreras
Constipation
Prebiotic Fructans Effect on 1-3 Years Constipated Children's Bowel Habits
The aim of the study is to confirm the effectiveness of chicory-derived prebiotic inulin-type fructans on bowel function in young children.
- Trial name
- CONSTICHILD (NCT03941925)
- Testing
- Prebiotic fructans, Non-prebiotic maltodextrin
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Drug Resistant Epilepsy
Role of the Gut Microbiota in Pediatric Epilepsy
Nearly a third of children with epilepsy are refractory to pharmacotherapy. The ketogenic diet (KD) is a highly effective alternative therapy reducing seizure frequency by 50% in more than half of treated children.
- Trial name
- EPBiome (NCT04705298)
- Testing
- Prebiotic
- Where
- 2 sites in Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- British Columbia Children's Hospital
Microbial Colonization, Tolerance
SEPSIS: L. Plantarum Trial
Sepsis is a life-threatening clinical syndrome and a leading cause of neonatal deaths worldwide. The burden of neonatal sepsis and severe infection (SI) is particularly high in areas of South Asia and other resource-limited…
- Conditions
- Microbial Colonization, Tolerance, Safety Issues, Infant ALL
- Trial name
- NCT05180201
- Testing
- Synbiotic, Probiotic
- Where
- 2 sites in Bangladesh
- Volunteers
- 519 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Healthy Infants
Study on the Effects of Probiotic on Infant Gut Microbiota and Immune Regulation
This is a probiotic intervention study in healthy infants aged 0 - 6 months. The primary objective is to evaluate the effects of Lacticaseibacillus paracasei LPB27 (also known as Lacticaseibacillus paracasei 207-27)…
- Trial name
- NCT07896083
- Testing
- Probiotic, Maltodextrin
- Where
- China
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- BYHEALTH Co., LTD
Iodine Deficiency Disorders
RCT of Iodine-containing MNPs vs Oral Iodized Oil to Prevent Iodine Deficiency in Weaning Infants
In this study, two intervention strategies to address iodine deficiency and prevent iodine deficiency disorders in breast-fed weaning infants will be evaluated in a mild to moderate iodine-deficient population in Zamboanga del…
- Trial name
- NCT02421653
- Testing
- MNP90, MNP45, IODISED OIL
- Volunteers
- healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Healthy
A Study to Evaluate the Impact of a Nutritional Product on Cognition in Healthy Teenagers
Nutritional products such as spearmint extract, alpha-glyceryl phosphoryl choline and phosphatidylserine may have anti-oxidative and anti-inflammatory effect that may be effective in improving cognition.
- Trial name
- NCT05548595
- Testing
- Investigational
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Hong Kong Prospect Group Co. Limited
Eczema, Allergy
LaCE (Lactobacillus Paracasei LPB27 On Early Childhood Eczema)
The LaCE study is a double-blind, randomised, placebo-controlled trial examining the effectiveness of the probiotic Lactobacillus paracasei LPB27 in treating eczema in young children.
- Trial name
- NCT06584552
- Testing
- Lactobacillus Paracasei LPB27, Maltodextrin
- Where
- Australia
- Volunteers
- 100 people
- Sponsor
- The University of New South Wales
Attention Deficit Hyperactivity Disorder, Anxiety
Effects of a Probiotic Supplement on Symptoms of Attention Deficit Hyperactivity Disorder and Anxiety in Children
The study will examine the effect of a probiotic supplement (Lactobacillus helveticus R0052 and Bifidobacterium Longum R0175) dissolved in a dairy product such as milk or ice-cream on symptoms of ADHD and anxiety in children.
- Trial name
- NCT02545634
- Testing
- L. helveticus R0052 and B. longum R0175
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Acadia University
Obesity, Inflammation
Examining the Relationship Between Acute Meal Intake and Inflammation in Children
Recent evidence has shown that obese and overweight children exhibit states of chronic inflammation. In obese adults, a high carbohydrate meal induces an inflammatory response; however, the effects of a high carbohydrate meal on…
- Trial name
- NCT03597542
- Testing
- Eggs and Carbohydrates
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Anemia, Iron Deficiency
Effect of Timing of Micronutrient Powder Consumption on Iron Absorption in Infants
Infants and young children in sub-Saharan Africa have high rates of iron deficiency anemia (IDA), which adversely affects their growth and cognitive development.
- Trial name
- NCT02989311
- Testing
- Fortified maize porridge (MNP and Iron), Fortified Maize porridge (MNP + Iron + GOS)
- Where
- Kenya
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Supplementation, Sport
Sodium Bicarbonate Supplementation in Combat Sports Athletes
The purpose of this study was to verify the effect of 10-day sodium bicarbonate (NaHCO3) and placebo (PLA) supplementation on physical and specific performance capacity, as well as concentrations of the selected biochemical blood…
- Trial name
- NCT03406065
- Testing
- Sodium bicarbonate supplementation
- Where
- Poland
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Poznan University of Life Sciences
Constipation
Study Comparing PEG 3350 Laxative to Placebo in the Treatment of Occasional Constipation (Study CL2007-12)(P08216)
Randomized, placebo-controlled, double blind study. 203 subjects entered the study to compare the effect on occasional constipation of polyethylene glycol 3350 to placebo. Subjects took one of study treatments up to 7 days.
- Trial name
- NCT00770432
- Testing
- Polyethylene glycol 3350
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Bayer
Atopic Dermatitis, Food Allergies
Probiotic Supplementation in Breastfed Newborn Infants
The purpose of this study is to investigate the dose of a probiotic supplement (Bifidobacterium longum subsp. infantis) required to achieve predominant gut colonization in healthy newborn, breastfed infants.
- Trial name
- NCT02286999
- Testing
- B. infantis
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Emanual Maverakis, MD
Signs and Symptoms, Digestive
Fiber Tolerability in Children Aged 3-7 Year
Determination of the digestive tolerability of the PROMITOR® in children from 3 to 7 years old.
- Trial name
- Fiber - TIC (NCT02677090)
- Testing
- Dose 1 - Promitor®, Dose 2 - Promitor®, Dose 3 - Promitor®
- Where
- France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Gastroenteritis
Emergency Department Probiotic Treatment of Pediatric Gastroenteritis
The objective of this study is to determine for previously healthy children who present to a Canadian Emergency Department (ED) with acute gastroenteritis (infection or irritation of the digestive tract); if compared with…
- Trial name
- NCT01853124
- Testing
- Lacidofil
- Where
- 6 sites in Canada
- Volunteers
- 886 people
- Sponsor
- Dr. Stephen Freedman
Celiac Disease
Prebiotic as a Supplement of Gluten-free Diet in the Management of Celiac Disease in Children
Prebiotics are known as substances affecting beneficially the organism by restoring the intestinal microbiota balance, stabilizing the intestinal barrier and modulating the endocrine and immune functions.
- Trial name
- NCT03064997
- Testing
- Synergy 1
- Where
- 2 sites in Poland
- Volunteers
- 34 people
- Sponsor
- Polish Academy of Sciences
Necrotizing Enterocolitis, Death
Probiotic Supplementation in Extremely Preterm Infants in Scandinavia
The primary aim of this research is to determine whether supplementation with probiotics during the first weeks of life reduces the risk of necrotizing enterocolitis (NEC) and neonatal mortality and is safe to use among extremely…
- Conditions
- Necrotizing Enterocolitis, Death, Sepsis Newborn, Feeding Disorder Neonatal
- Trial name
- PEPS (NCT05604846)
- Testing
- ProPrems
- Where
- Sweden
- Volunteers
- 1,600 people
- Sponsor
- Region Stockholm
Endothelial Dysfunction
Bioefficacy of Phenolic Acids
The objective is to demonstrate the effect of phenolic acids on endothelial function.
- Trial name
- NCT01781559
- Testing
- phenolic acid
- Where
- Australia
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Sickle Cell Anemia, Sickle ß0-Thalassemia
A Phase III Safety and Efficacy Study of L-Glutamine to Treat Sickle Cell Disease or Sickle βo-thalassemia
The purpose of this research is to evaluate the effects of L-glutamine as a therapy for Sickle Cell Anemia or Sickle ß0 Thalassemia as evaluated by the number of occurrences of sickle cell crises.
- Trial name
- NCT01179217
- Testing
- L-glutamine
- Where
- 31 sites in United States
- Volunteers
- 230 people
- Sponsor
- Emmaus Medical, Inc.