Clinical trials: Methylphenidate
Attention Deficit Disorder With Hyperactivity, Attention Deficit Disorder
Adverse Effect of Prolonged Methylphenidate Treatment on Cardiac Functions
The purpose of this study is to find out whether prolonged treatment with methylphenidate has any adverse effect on cardiac functions and measurements.
- Conditions
- Attention Deficit Disorder With Hyperactivity, Attention Deficit Disorder, Attention Deficit Hyperactivity Disorder, Attention Deficit Disorders With Hyperactivity
- Trial name
- NCT00372359
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Ornit Cohen
ADHD
Adherence to Stimulant Treatment in Attention-Deficit Hyperactivity Disorder (ADHD) Patients (ASTA)
This study determined to measure non-adherence assessed by the number of non-adherent days during the clinical trial of 100 days using the Medication Event Monitoring System (MEMS).
- Trial name
- ASTA (NCT00852059)
- Testing
- Immediate release methylphenidate (Medikinet®), Extended release methylphenidate (Medikinet retard®)
- Where
- Germany
- Volunteers
- 32 people
- Sponsor
- Prof. Huss
ADHD, Probiotics
Effect of Probiotics on ADHD
Attention-Deficit/Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder. Gut microbiome dysbiosis may be associated with the pathophysiology of ADHD.
- Conditions
- ADHD, Probiotics, Gut Microbiota, Psychiatry
- Trial name
- NCT04958460
- Testing
- BF688
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Wang Liang-Jen
Acute Lymphoblastic Leukemia, Brain Tumors
Learning Impairments Among Survivors of Childhood Cancer
Children surviving some types of cancer have a higher risk of developing learning problems after cancer treatment than do children who have not had cancer or its treatment.
- Trial name
- NCT00576472
- Testing
- Methylphenidate
- Where
- 3 sites in United States
- Volunteers
- 469 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Attention Deficit Hyperactivity Disorder
Methylphenidate and the Relations Between Emotional Processing and Social Functioning Among Children With ADHD
Children with ADHD are in high risk to develope social difficulties. The present study will examine the emotional processing in those children.
- Trial name
- NCT01278667
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Bnai Zion Medical Center
Attention Deficit Hyperactivity Disorder, ADHD
Efficacy and Safety of Methylphenidate HCl ER Capsules in Children and Adolescents With ADHD
This multi-center parallel study is designed to study the efficacy and safety of fixed doses of methylphenidate extended release (ER) capsules of four dose levels compared with a placebo group in pediatric patients with Attention…
- Trial name
- NCT01239030
- Testing
- Methylphenidate Hydrochloride Extended Release Capsules
- Where
- 16 sites in United States
- Volunteers
- 230 people
- Sponsor
- Rhodes Pharmaceuticals, L.P.
ADHD
Systematic Aerobics and Intelligent Monitoring System in Executive Skill Training for School-aged Children With ADHD
Around 7.2% of children around the world are suffering from Attention Deficit Hyperactivity Disorder (ADHD). Systematic executive skill training for children is currently recognized as one of the main programs for psychosocial…
- Trial name
- NCT05668195
- Testing
- systematic aerobic exercise and intelligent monitoring system in executive skill training, executive skill training
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chen Li
Attention Deficit Hyperactivity Disorder
Large-scale Brain Organization During Cognitive Control in ADHD
The purpose of this study is to test whether children with attention-deficit/hyperactivity disorder (ADHD) are impaired in the ability to flexibly adapt brain network organization in response to shifting cognitive demands during…
- Trial name
- NCT04349917
- Testing
- Methylphenidate
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of North Carolina, Chapel Hill
Attention Deficit Hyperactivity Disorder
The Effect of Methylphenidate Versus Placebo on State Anxiety in Children With Attention Deficit Hyperactivity Disorder.
The purpose of the study is to explore the effect of methylphenidate on state anxiety in children with attention deficit hyperactivity disorder.
- Trial name
- NCT01798459
- Testing
- Methylphenidate
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shalvata Mental Health Center
Attention Deficit Hyperactivity Disorder, ADHD
Imaging Stimulant and Non Stimulant Treatments for ADHD: A Network Based Approach
The growing number of medications used to treat attention-deficit/hyperactivity disorder (ADHD) raises important questions about whether different medications have similar or different therapeutic mechanisms of action.
- Trial name
- NCT01678209
- Testing
- fMRI scans, Atomoxetine arm, Methylphenidate arm
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Emotional Dysregulation, Externalizing Problems
Assessing Real Life Effectiveness of Treatment in Neurodevelopmental Disorders
The goal of this observational study is to learn if and how pharmacological and psychotherapeutic group treatments can treat clinical symptoms of children and adolescent patients with ADHD.
- Conditions
- Emotional Dysregulation, Externalizing Problems, Oppositional Defiant, Conduct Disorder
- Trial name
- ALERT (NCT07273695)
- Testing
- methyphenidate, Group psychological treatment
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- IRCCS Eugenio Medea
Attention Deficit Hyperactivity Disorder Combined
Biomarker Validation in Motor System Physiology in Attention Deficit Hyperactivity Disorder
Attention-Deficit/Hyperactivity Disorder (ADHD) is the most commonly diagnosed neurobehavioral disorder in childhood. Children with ADHD struggle in school due to problems with attention and high levels of impulsivity and…
- Trial name
- AMPAIII (NCT04421248)
- Testing
- Methylphenidate
- Where
- 2 sites in United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Donald Gilbert, MD, MS, FAAN, FAAP
ADHD
EEG Biomarkers for ADHD Stimulant Treatment
Pediatric attention deficit hyperactivity disorder (ADHD) affects up to 10% of children in the U.S. and more than 90% are prescribed stimulant medications according to clinical guidelines.
- Trial name
- NCT07650643
- Testing
- methylphenidate HCl, Mixed amphetamine salts extended release
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Boston Children's Hospital
Attention Deficit Hyperactivity Disorder
Clinical and Pharmacogenetic Study of Attention Deficit With Hyperactivity Disorder (ADHD)
Attention deficit with hyperactivity disorder (ADHD) is a very common behavioral problem during childhood. It is estimated that up to 80% of this disorder could be related to genetic factors.
- Trial name
- NCT00483106
- Testing
- Ritalin
- Where
- Canada
- Volunteers
- 885 people
- Sponsor
- McGill University
Attention Deficit Hyperactivity Disorder, Sleep Onset Insomnia
Comparing Treatment With Melatonin to Treatment With Stimulants (Methylphenidate) in Children With Attention Deficit Hyperactivity Disorder and Sleep Difficulties
The study hypothesis is that some children with Attention-Deficit-Hyperactivity-Disorder (ADHD) who also have sleep onset difficulties will improve with Melatonin treatment to an extent similar to that of stimulants treatment.
- Trial name
- NCT01393574
- Testing
- Melatonin, Methylphenidate
- Where
- Israel
- Volunteers
- 46 people
- Sponsor
- Assaf-Harofeh Medical Center
Autism, Attention Deficit Hyperactivity Disorder
A Pilot Study of Daytrana TM in Children With Autism Co-Morbid for Attention Deficit Hyperactivity Disorder (ADHD) Symptoms
This is an open-label study of the efficacy of Daytrana (methylphenidate transdermal system) for the treatment of attention and behavioral symptoms in children with Autism Spectrum Disorders.
- Trial name
- NCT00541346
- Testing
- Methylphenidate Transdermal System
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Oklahoma
Attention Deficit Hyperactivity Disorder
Community-based Study Comparing Extended-release Methylphenidate and Atomoxetine in Children With Attention-deficit Hyperactivity Disorder
The purpose of this study was to better understand the treatment outcomes of extended-release methylphenidate and atomoxetine in children with attention-deficit hyperactivity disorder (ADHD) as evaluated by physicians and parents…
- Trial name
- NCT00866996
- Testing
- Methylphenidate extended-release; Atomoxetine
- Volunteers
- 1,323 people
- Sponsor
- McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.
Attention Deficit Hyperactivity Disorders
Low-dose vs. Normal-dose Psychostimulants on Executive Functions in Individuals With ADHD
This double-blind crossover study aims to compare cognitive performance (e.g., working memory, selective attention and cognitive flexibility) of children ages 6-18 years diagnosed with ADHD of the combined type (ADHD-C) or…
- Trial name
- NCT02167048
- Testing
- Psychostimulants
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
ADHD
Long-Term Safety of PRC-063 in Adolescents and Adults With ADHD
The purpose of this six month, open-label study is to evaluate the long-term safety and efficacy of PRC-063 in adults and adolescents with ADHD.
- Trial name
- NCT02168127
- Testing
- Drug: PRC-063, PRC-063
- Where
- 35 sites in United States, Canada
- Volunteers
- 360 people
- Sponsor
- Rhodes Pharmaceuticals, L.P.
Attention Deficit Hyperactivity Disorder
Psychometric Validation of the Competitive Attention Test
This project aims at validating a new neuropsychological test to measure voluntary and involuntary attention for clinical use to diagnose attentional deficits.
- Trial name
- CAT (NCT03942835)
- Testing
- experience 1 : Competitive attention test in healthy participants, experience 2 : Competitive attention test in patients with ADHD with no treatment, experience 3 :Competitive attention test in patients with ADHD with psychostimulant treatment
- Where
- France
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon