Clinical trials: Oxycodone
Liquid Oxycodone
The Effect of General Anesthesia on Pharmacokinetics of Oxycodone in Pediatric
Oxycodone is an oral opioid analgesic that is most commonly prescribed for the management of pain in post-operative patients at Boston Children's Hospital.
- Trial name
- NCT03054831
- Testing
- liquid oxycodone
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Boston Children's Hospital
Preeclampsia Severe, Preeclampsia Postpartum
Preeclampsia And Nonsteroidal Drugs for Analgesia: a Randomized Non Inferiority Trial
A randomized non-inferiority trial of women with preeclampsia with severe features to determine if the addition of nonsteroidal anti-inflammatory drugs is inferior or non-inferior to standard analgesic bundles in their impact on…
- Trial name
- PANDA (NCT03978767)
- Testing
- Ibuprofen 600 mg, Ketorolac, Acetaminophen
- Where
- United States
- Volunteers
- 287 people
- Sponsor
- Washington University School of Medicine
Post Tonsillectomy Pain
A Comparative Study With Parenteral Oxycodone, Morphine and Dexamethasone in Postoperative Pain in Paediatric Patients
The aim of this randomized, double-blind study is to compare parenteral pre-emptive oxycodone, morphine and dexamethasone with placebo in the treatment of postoperative pain in paediatric patients 4 to 12 years of age.
- Trial name
- DOM (NCT00733083)
- Testing
- 0,1 mg/kg of oxycodone, Morphine 0,1 mg/kg, Dexamethasone 0,5 mg/kg
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- University of Turku
Pain, Postoperative
Opioids Following ACL
The purpose of this study is to evaluate the effectiveness of a post-operative opioid pain 18 management protocol for anterior cruciate ligament reconstruction (ACLR).
- Trial name
- NCT04278703
- Testing
- Oxycodone
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Rothman Institute Orthopaedics
Periacetabular Osteotomy, Opiates
Open-label Placebo for Pain Management in Adolescents and Young Adults Undergoing Bernese Periacetabular Osteotomy
In this randomized controlled trial, 64 participants undergoing PAO at UCSF will be enrolled and randomized to receive either COLP plus treatment as usual (TAU) or TAU alone.
- Trial name
- COLP PAO (NCT07373210)
- Testing
- Treatment as usual
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of California, San Francisco
Anterior Cruciate Ligament Injuries
Reduce Opiate Exposure With ACL Surgery
This is a randomized control trial to investigate the effectiveness of a multimodal opiate sparing analgesic regimen in controlling post-operative pain and potentially reduce post-operative opioid consumption in patients…
- Trial name
- NCT06561035
- Testing
- Opiate Sparing, Opiate Based
- Where
- 3 sites in United States
- Volunteers
- 56 people
- Sponsor
- Campbell Clinic
Patient-Controlled Analgesia
Nausea and Vomiting in Postoperative Paediatric Patients With Patient-Controlled Analgesia (PCA): Morphine vs Oxycodone
POPCORN trial will compare the side effects and effectiveness of Morphine versus Oxycodone medication when prescribed for use as patient controlled analgesia (PCA) for pain relief for paediatric patients after-surgery.
- Trial name
- POPCORN (NCT06186141)
- Testing
- Morphine, Oxycodone
- Where
- Australia
- Volunteers
- 690 people
- Sponsor
- Murdoch Childrens Research Institute
Opioid Analgesia
Pharmacokinetics and Safety of ORF Tablets in Pediatric Patients
The purpose of this study is to characterize the pharmacokinetics (PK) of single-dose ORF tablets in pediatric patients aged 6 to 16 years, inclusive.
- Trial name
- NCT01160614
- Testing
- Oxycodone hydrochloride controlled-release (ORF) tablets
- Where
- 17 sites in United States, Australia and 2 more
- Volunteers
- 30 people
- Sponsor
- Purdue Pharma LP
Critical Illness
Clinical Trial on Individual Characteristics Affecting Pain Drug Therapy in Neonates
Children differ from adults with respect to growth and development but also immaturity of various pharmacological mechanisms. Dosing schemes in children are usually derived in an empirical manner from clinical trials in adult…
- Trial name
- NeoPopGen (NCT02426463)
- Testing
- propofol, oxycodone
- Where
- Finland
- Volunteers
- 80 people
- Sponsor
- Turku University Hospital
Limb Fracture
Ethnicity and Analgesic Practice in a Pediatric Emergency Department
Early and appropriate pain management in the emergency department (ED) is an important aspect of child care. Studies in the adult population revealed that ethnicity might be associated with disparities in analgesia and opioid…
- Trial name
- NCT02322463
- Testing
- Arab children
- Where
- Israel
- Volunteers
- 5,000 people
- Sponsor
- Rambam Health Care Campus
Tonsillectomy
Celecoxib After Tonsillectomy
Tonsillectomy is one of the most common pediatric surgical procedures in the United States. Postoperative pain is substantial, with typical regimens employing narcotic derivatives and acetaminophen for 1-2 weeks after surgery.
- Trial name
- NCT02934191
- Testing
- Celecoxib, Acetaminophen, Oxycodone
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- Children's Hospital of Philadelphia
Surgery, Pain, Post Operative
Comparing Analgesic Regimen Effectiveness and Safety for Surgery for Kids Trial
This trial is being completed to compare two commonly used options to treat pain after discharge from surgery. Participants that undergo tonsil removal, gallbladder removal, and knee scope will be eligible to enroll.
- Trial name
- CARES for Kids (NCT06671002)
- Testing
- NSAID, Opioid, Acetaminophen
- Where
- 9 sites in United States
- Volunteers
- 900 people
- Sponsor
- University of Michigan
Pain
Fixed-dose Combination of Oxycodone [OXIcodona] + IbuproFEN in Pain Relief After Third Molar Extraction
A clinical, multicenter, randomized, parallel-group, double-blind, double-dummy, comparative study of non-inferiority. ⚠️Study will only be conducted in research centers in Brazil (please do not send e-mail if your center is…
- Trial name
- OXIFEN (NCT05081102)
- Testing
- FDC of oxycodone 5 mg/ibuprofen 400 mg, Tylex
- Where
- Brazil
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Eurofarma Laboratorios S.A.
Baseline Epidemiologic Assessment
Baseline Epidemiologic Assessment of Abuse-Deterrence of MorphaBond Extended Release (BEAD-MB)
The main objectives of this study are to provide surveillance/descriptive data to (a) assess utilization of MorphaBond ER and selected comparators overall and by age group and census regions using nationally-projected quarterly…
- Trial name
- BEAD-MB (NCT04033094)
- Testing
- MorphaBond ER, Comparator Drug
- Where
- United States
- Volunteers
- 17,566 people
- Sponsor
- Daiichi Sankyo
Children, Lacerations
Pain and Anxiety Management With Oral Narcotic for Pediatric Suture Repair
The purpose of this study is: To determine whether oral narcotic medication versus placebo improves the pain and anxiety scores for pediatric patients requiring laceration repair in the pediatric emergency department and…
- Conditions
- Children, Lacerations, Procedures, Child
- Trial name
- NCT01053637
- Testing
- hydrocodone/acetaminophen, Sugar water
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Baylor College of Medicine
Forearm Injuries, Pain, Acute
Pain Control Differences Between Oxycodone and Ibuprofen in Children With Isolated Forearm Injuries
Children presenting to the Emergency Room with the chief complaint of forearm injury and/or pain will be randomized to receive oral Oxycodone or Ibuprofen to control pain.
- Conditions
- Forearm Injuries, Pain, Acute, Pediatric ALL
- Trial name
- NCT04523623
- Testing
- Oxycodone, Ibuprofen
- Sponsor
- Washington University School of Medicine
Opioid Use, Unspecified
Investigating Interventions to Reduce Residual Opioids in the Home Following Legitimate Opioid Prescribing in Children.
The overall objective of this study is to evaluate strategies to reduce unused opioids prescribed for pediatric acute post-surgical pain management.
- Trial name
- NCT04219397
- Testing
- Medication take back, Medication home disposal
- Where
- 2 sites in United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Indiana University
Pain
Evaluate The Pharmacokinetics and Safety Of Oxycodone Oral Solution In Pediatric and Adolescent Subjects
The objective of this study is to characterize the pharmacokinetics and to evaluate the safety of single and multiple doses of Oxycodone Oral Solution in pediatric and adolescent subjects for postoperative pain.
- Trial name
- NCT01959204
- Testing
- Oxycodone
- Where
- 9 sites in United States
- Volunteers
- 97 people
- Sponsor
- VistaPharm, Inc.
Supracondylar Humerus Fracture
Supracondylar Post-Operative Pain Study
The purpose of this study to investigate post-operative pain control in pediatric patients with closed supracondylar humerus fracture who undergo closed reduction and percutaneous pinning.
- Trial name
- NCT03759028
- Testing
- Ibuprofen, Oxycodone, Acetaminophen
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of California, Los Angeles
Opioid Related Disorders, Opiate Addiction
Evaluation of Changes in Prescribing Behavior of ER/LA Opioid Prescribers
A study will be performed to evaluate changes in prescribing behavior of prescribers of ER/LA opioids
- Conditions
- Opioid Related Disorders, Opiate Addiction, Narcotic Abuse, Drug Abuse
- Trial name
- NCT02920762
- Testing
- on-interventional study - retrospective database review
- Volunteers
- 5,575,834 people
- Sponsor
- ER/LA Opioid REMS Program Companies (RPC)