Clinical trials: Physical Therapy
Autism Spectrum Disorder, Childhood
Preliminary Exploration of the Usability of a Structured Plate to Improve Eating Behaviors in Children With Autism Spectrum Disorder and Its Impact on the Family: A Pilot Study
This completed single-arm pilot study examined the usability of a structured plate during routine classroom mid-morning snacks in children with autism spectrum disorder and feeding difficulties.
- Conditions
- Autism Spectrum Disorder, Childhood, Feeding Difficulties
- Trial name
- PlaTEA (NCT07516431)
- Testing
- Structured Plate
- Where
- Spain
- Volunteers
- 6 people
- Sponsor
- Universidad de Zaragoza
Substance Use, Conduct Disorder
Early Family-Centered Prevention of Drug Use Risk (Aka Early Steps)
The investigators are testing the efficacy of a family-based preventive intervention, which began when the children were age 2, with children at risk for developing significant conduct problems.
- Conditions
- Substance Use, Conduct Disorder, Depression, Anxiety
- Trial name
- Early Steps (NCT01098695)
- Testing
- Ecological Family Intervention and Treatment (EcoFIT)
- Where
- 3 sites in United States
- Volunteers
- 731 people
- Sponsor
- University of Oregon
Overweight, Obesity
Two-year Research Study Investigating How Well Semaglutide Works in People Suffering From Overweight or Obesity
This study will look at the change in body weight from the start to the end of the study. Researchers will compare the weight loss in people taking semaglutide (a new medicine) to people taking "dummy" medicine.
- Trial name
- STEP 5 (NCT03693430)
- Testing
- Semaglutide
- Where
- 41 sites in United States, Canada and 3 more
- Volunteers
- 304 people
- Sponsor
- Novo Nordisk A/S
Cardiology, Nefrology
Telerehabilitation in Hemodialysis Patients.
Chronic kidney disease is the third most common cause of death, with a prevalence of 10-12%. Patients undergoing hemodialysis often exhibit low levels of physical activity, leading to various health issues, including poor quality…
- Trial name
- Teledialysis (NCT06891482)
- Testing
- Telerehabilitation
- Where
- Belgium
- Volunteers
- 46 people
- Sponsor
- Hartcentrum Hasselt
Psychopathic Personality Trait
Can Psychopathy be Prevented? Clinical, Neuroimaging and Genetic Data
The goal of this clinical trial was to learn about the effect of maltreatment on psychological and brain characteristics in a group of children.
- Trial name
- NCT06028620
- Testing
- Trauma Focused-Cognitive Behavior Therapy
- Where
- Mexico
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Mexico
Cerebral Palsy
Robotic Exoskeleton Gait Training in Adolescents With Cerebral Palsy
The study design will consist of a cohort of adolescents and young adults with cerebral palsy (CP) that will undergo a gait training protocol.
- Trial name
- NCT05158218
- Testing
- Robotic Exoskeleton Gait Therapy, Physical Therapy
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Father Flanagan's Boys' Home
Chronic Obstructive Pulmonary Disease, Neuromuscular Disease
Telemedicine and Ventilator Titration in Chronic Respiratory Patients Initiating Non-invasive Ventilation
The critical nature of respiratory diseases, the continuously increasing prevalence of these conditions, and the subjective perception of patients vis-à-vis their pulmonary function and health status underscore the importance of…
- Conditions
- Chronic Obstructive Pulmonary Disease, Neuromuscular Disease, Chest Wall Disorders, Obesity Hypoventilation Syndrome
- Trial name
- TeleMotiNIV (NCT01560741)
- Testing
- Telemonitoring tools, Usual Care
- Where
- Portugal
- Volunteers
- 128 people
- Sponsor
- Hospital Sao Joao
Anterior Cruciate Ligament Reconstruction
AlterG ACL Return to Running Case Series
This case series will follow standard ACL protocol, while using biomechanical movement analysis to analyze running mechanics using a body weight supported treadmill.
- Trial name
- NCT02335645
- Testing
- Body Weight Supported Treadmill Use of Patients with ACL Reconstruction
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Nationwide Children's Hospital
Arthrogryposis, Craniofacial Abnormalities
Study of Quality of Life in Freeman-Sheldon Syndrome and Related Conditions
Freeman-Sheldon syndrome (FSS) is a rare human neuromusculoskeletal disorder present before birth, involving primarily limb and craniofacial deformities.
- Conditions
- Arthrogryposis, Craniofacial Abnormalities, Posttraumatic Stress Disorder, Depressive Disorder
- Trial name
- FSS-QLS (NCT01307475)
- Testing
- PTSD Checklist-Specific, Modified Flanagan Quality of Life Scale, Center for Epidemiologic Studies Depression Scale
- Where
- 2 sites in United States, Guatemala
- Volunteers
- 6 people
- Sponsor
- Freeman-Sheldon Research Group, Inc.
Autism Spectrum Disorder, Depression - Major Depressive Disorder
Mental Health, Intellectual and Neurodevelopmental Disorder Detection With Artificial Intelligence Models
This study investigates whether AI-driven analysis of speech can accurately predict clinical diagnoses and assess risk for various mental or behavioral health conditions, including attention-deficit/hyperactivity disorder (ADHD)…
- Conditions
- Autism Spectrum Disorder, Depression - Major Depressive Disorder, Anxiety, Generalized, Bipolar Disorder (BD)
- Trial name
- MINDAIM (NCT06792175)
- Testing
- Solicue Machine Learning Models, Mercuria Machine Learning Models
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- Psyrin Inc.
Sciatica Pain
The Impact of High Frequency Electrical Nerve Stimulation and Chiropractic Care on Sciatic Axonal Lesion Presenting as Painful Leg: Case Report
To present an evidence-based case report on the prognosis of a pediatric patient with right sciatica and painful leg. A 5-year-old girl with limping gait, presented with right-sided buttock and lower extremity pain and numbness.
- Trial name
- NCT05923957
- Testing
- TENS and Exercise
- Where
- Egypt
- Volunteers
- 1 people
- Sponsor
- Prince Sattam Bin Abdulaziz University
Rehabilitation
Integration of Real-Time Motion Tracking and Pediatric Rehabilitation
Emerging technologies that utilize motion capture integrated with engaging software offer new methods for increasing engagement and movement in patients admitted to the hospital.
- Trial name
- Snipperfinger (NCT06924801)
- Testing
- Snipperfingers
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Acute Ischemic Stroke (AIS), Stroke-Associated Pneumonia (SAP)
Oral Care Strategies for Stroke Patients with Dysphagia
This study aims to evaluate whether combining neuromuscular electrical stimulation (NMES) with oral care can improve swallowing function in patients who have experienced an acute stroke and are dealing with dysphagia (difficulty…
- Conditions
- Acute Ischemic Stroke (AIS), Stroke-Associated Pneumonia (SAP), Dysphagia Following Cerebrovascular Accident
- Trial name
- NCT06692101
- Testing
- oral care, Neuromuscular Electrical Stimulation (NMES)
- Where
- Taiwan
- Volunteers
- 35 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Children Who Need Circumcision
Assessment of Hemodynamic Response in Surgery of Circumcision in Children
The surgery stress relives systemic inflammatory response by hormones and adrenergic receptors. When the pro-inflammatory mediator is higher than anti-inflammatory response, the physiologic status is impaired and the patient is…
- Trial name
- NCT00943475
- Testing
- circumcision
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federal University of Juiz de Fora
Unspecified Childhood Solid Tumor, Protocol Specific
Pharmacokinetics of Daunorubicin in Young Patients With Cancer
This laboratory study is looking at the pharmacokinetics of daunorubicin in young patients with cancer. Collecting and storing samples of blood from patients with cancer to study in the laboratory may help doctors learn more…
- Trial name
- NCT00673257
- Testing
- pharmacological study, dual x-ray absorptimetry
- Where
- 60 sites in United States, Australia and 2 more
- Volunteers
- 107 people
- Sponsor
- Children's Oncology Group
Antimicrobial Resistance
Algorithm Using a Rapid Diagnostic Test for the Management of Childhood Febrile Diseases.
In Sub-Saharan Africa (SSA), fever remains a major public health problem in children. The introduction of malaria rapid diagnostic tests (RDTs) in routine healthcare has greatly improved the management of malaria.
- Trial name
- e-MANIC (NCT05285657)
- Testing
- Two-step malaria RDT detecting PfHRP2/pLDH (SD Ag Bioline Malaria Ag P.f/Pan: Standard Diagnostics, Hagal-Dong, Korea)
- Where
- 2 sites in Burkina Faso
- Volunteers
- 1,176 people
- Sponsor
- Institut de Recherche en Sciences de la Sante, Burkina Faso
Bronchiolitis
Chest Physiotherapy in Bronchiolitis
Randomized trial of chest physiotherapy in outpatients with bronchiolitis under two years of age, during two consecutive seasonal outbreaks.
- Trial name
- NCT04260919
- Testing
- Chest physiotherapy
- Volunteers
- 45 people
- Sponsor
- Universidade do Porto
Concussion, Mild
Impact of a Paced Breathing Exercise Intervention on Autonomic Nervous System Function After Pediatric Concussion
The goal of this pilot clinical trial is to assess the feasibility of administering a paced breathing exercise intervention program to children and adolescents in the sub-acute period after concussion, and to document the…
- Trial name
- Breathe (NCT06559865)
- Testing
- Breathing exercises
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Diffuse Midline Glioma (DMG), Glioblastoma
ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors
This phase I trial studies the effects and best dose of ONC206 alone or in combination with radiation therapy in treating patients with diffuse midline gliomas that is newly diagnosed or has come back (recurrent) or other…
- Conditions
- Diffuse Midline Glioma (DMG), Glioblastoma, Recurrent Ependymoma, Recurrent Malignant Central Nervous System Neoplasm
- Trial name
- PNOC023 (NCT04732065)
- Testing
- ONC206, Standard of Care Radiation Therapy, Optional Proton (1H) MR spectroscopy (MRS)
- Where
- 7 sites in United States, Netherlands and 1 more
- Volunteers
- 208 people
- Sponsor
- Sabine Mueller, MD, PhD
Anorexia Nervosa, Dysmorphophobia
Virtual Reality Place in the Management of Body Dysmorphia Disorders in Anorexia Nervosa
Body distortions are responsible for anorexic behavior reinforcing loops. It is necessary to target this behavior and develop appropriate therapies taking into account the perceptual (implicit) and conceptual (explicit)…
- Trial name
- PROSANOR (NCT04804800)
- Testing
- Experimental group 1 : Virtual Reality, Experimental group 2 : Virtual Reality + Multi Sensorial Remediation
- Volunteers
- 150 people
- Sponsor
- Lille Catholic University
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