Clinical trials: Prednisolone
Pain, Postoperative, Post-Craniotomy Headache
Scalp Infiltration With Methylprednisolone Plus Ropivacaine for Post-Craniotomy Pain in Children
At present, pediatric postoperative analgesia has not been fully understood and controlled, particularly craniotomy surgery. On the one hand, professional evaluation of postoperative pain for young children is difficult; on the…
- Trial name
- NCT03636165
- Testing
- Methylprednisolone, Ropivacaine
- Volunteers
- 90 people
- Sponsor
- Beijing Tiantan Hospital
Hepatitis
Severe Hepatitis Intervention With Emapalumab for Liver Disease
The goal of this study is to see whether a medicine called emapalumab, a monoclonal antibody, is safe and works well for patients aged 1 year and older who have indeterminate severe hepatitis with T-cell activation and have not…
- Trial name
- SHIELD (NCT07744919)
- Testing
- Emapalumab
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Children's Healthcare of Atlanta
Haematopoietic Stem Cell Transplantation
Precision Medicine for Stem Cell Transplantation
A study of patients undergoing haematopoietic stem cell transplantation, a procedure in which patients are infused with stem cells from a donor, resulting in a new immune system that eliminates cancer or replaces diseased bone…
- Trial name
- PM-SCT (NCT05567289)
- Testing
- Blood sample collection, Bone marrow aspirate
- Where
- 3 sites in United Kingdom
- Volunteers
- 300 people
- Sponsor
- University of Manchester
Mycoplasma Pneumoniae Pneumonia
Methylprednisolone for Children With Severe Mycoplasma Pneumoniae Pneumonia (MCMP)
The study is designed to investigate difference in percentage of presentation of atelectasis, bronchiectasis, bronchiolitis obliterans, or consolidation in 6 months after discharge in those treated with a low dose regimen of…
- Trial name
- NCT02303587
- Testing
- methylprednisolone
- Where
- China
- Volunteers
- 424 people
- Sponsor
- Beijing Children's Hospital
Myasthenia Gravis
Hematopoietic Stem Cell Therapy for Patients With Refractory Myasthenia Gravis
MG may be neonatal, congenital, or autoimmune. Neonatal MG arises from transplacental transfer of ACh receptor antibodies from a mother with autoimmune MG to the fetus.
- Trial name
- NCT00424489
- Testing
- Hematopoietic Stem Cell Transplantation, Cyclophosphamide, ATG (rabbit)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Northwestern University
Lymphoma
Combination Chemotherapy in Treating Children With Non-Hodgkin's Lymphoma
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells.
- Trial name
- NCT00003650
- Testing
- asparaginase, cyclophosphamide, cytarabine
- Where
- France
- Volunteers
- 179 people
- Sponsor
- UNICANCER
Tonsillectomy
Postoperative Oral Corticosteroids Following Tonsillectomy
Tonsillectomy is one of the most common surgical procedures in the United States, and post-operative pain management is a challenge for otolaryngologists.
- Trial name
- NCT03352115
- Testing
- Prednisolone
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia
Allo HSCT Using RIC for Hematological Diseases
This is a phase II trial using a non-myeloablative cyclophosphamide/ fludarabine/total body irradiation (TBI) preparative regimen followed by a related or unrelated donor stem cell infusion.
- Conditions
- Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia, Chronic Myelogenous Leukemia, Plasma Cell Leukemia
- Trial name
- NCT02661035
- Testing
- Allopurinol, Fludarabine, Cyclophosphamide
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- Masonic Cancer Center, University of Minnesota