Clinical trials: Propranolol
Stress Disorders, Traumatic, Acute
Propranolol for the Treatment of Acute Stress Disorder
This 10-week study will examine whether propranolol, a medication that blocks the activity of the stress hormones adrenaline and noradrenaline, can relieve acute stress disorder (ASD) and symptoms from persisting long-term.
- Trial name
- NCT00069355
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Institute of Mental Health (NIMH)
Anxiety
Efficacy of Clonidine and Propranolol in Dentistry (AAA)
The aim of the study is to determine the efficacy of clonidine and propranolol for transient anxiety management and intra and postoperative pain in patients undergoing ambulatory surgery of third molar.
- Trial name
- NCT01784250
- Testing
- Clonidine, Propranolol
- Where
- Colombia
- Volunteers
- 60 people
- Sponsor
- CES University
Portal Hypertension, Biliary Atresia
Primary Prophylaxis for Variceal Bleed in Biliary Atresia
Biliary atresia is the commonest etiology of neonatal cholestasis and is the most common indication for pediatric liver transplantation world-wide.
- Trial name
- BA-BB (NCT04494763)
- Testing
- Propanolol
- Where
- India
- Volunteers
- 92 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Postoperative Chylothorax, Congenital Heart Disease
Propranolol Treatment for Postoperative Chylothorax
Postoperative chylothorax is a serious complication after open heart surgery for pediatric patients with congenital heart disease (CHD).
- Conditions
- Postoperative Chylothorax, Congenital Heart Disease, Open Heart Surgery, Chylothorax
- Trial name
- NCT06833320
- Testing
- Propranolol Hydrochloride
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- June Wu
Infantile Hemangioma
''Efficacy of Propranolol in the Treatment of Infantile Hemangioma"
''Evaluation of the Efficacy of Propranolol in the Treatment of Infantile Hemangioma"
- Trial name
- NCT04684667
- Testing
- Propranolol Therapy for Infantile Hemangioma
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Recurrent Neuroblastoma
Metronomic Treatment in Children and Adolescents With Recurrent or Progressive High Risk Neuroblastoma
Neuroblastoma is the second most frequent cause for death from cancer in childhood. Already one year after diagnosis of recurrence from high risk neuroblastoma, 75% of the patients experience further progression.
- Trial name
- METRO-NB2012 (NCT02641314)
- Testing
- metronomic therapy
- Where
- 8 sites in Germany
- Volunteers
- 18 people
- Sponsor
- University of Cologne
Duration of Labor
Does Oral Propranolol Accelerate Labor Induction/Augmentation With Oxytocin in Nulliparous Women in Abakaliki?
Labour is usually physiologic, spontaneous and progressive, but occasionally, there may be the need for induction or augmentation of labour especially in nulliparous women, who are at increased risk of dysfunctional labour.
- Trial name
- NCT05251610
- Testing
- 20mg oral propranolol and oxytocin, Oxytocin only
- Where
- Nigeria
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Darlington-Peter Chibuzor Ugoji
Primary Lymphedema
Propranolol Dose Escalation in Lymphedema in Patients
This is a study to investigate the safety and efficacy of propranolol in the treatment of patients with primary lymphedema. The primary goal is to assess patient tolerability of increasing doses of propranolol.
- Trial name
- NCT02595996
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Columbia University
Hemangioma
A Clinical Trial of Pulsed-dye Laser Versus Timolol Topical Solution Versus Observation on the Growth of Hemangioma in Newborn
The purpose of this study is to find out if pulsed dye laser treatment or timolol maleate 0.5% gel can help infants who have a hemangioma.
- Trial name
- NCT01873131
- Testing
- topical timolol maleate, Pulsed dye laser
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Esophageal Varices in Cirrhosis of the Liver, Upper Gastrointestinal Bleeding
Endoscopic Variceal Ligation in Children
This is an ambispective single-center cohort study of pediatric patients with portal hypertension and esophageal varices. The study was designed to evaluate the efficacy and safety of primary prophylaxis with endoscopic variceal…
- Conditions
- Esophageal Varices in Cirrhosis of the Liver, Upper Gastrointestinal Bleeding, Endoscopy, Child
- Trial name
- NCT03943784
- Testing
- Endoscopic Variceal Ligation, Non-Selective Beta-Blocking Agent
- Volunteers
- 60 people
- Sponsor
- Hospital Vall d'Hebron
Migraine Headache
Cupping and Serkangabin Versus Conventional Migraine Treatment
Migraine is the most common recurrent headache. Current therapy of migraine headache consists of multiple drug groups for control of attack and prophylaxis against recurrent attacks.
- Trial name
- NCT01476930
- Testing
- cupping and serkangabin syrup, conventional migraine drug treatment
- Where
- Iran
- Volunteers
- 391 people
- Sponsor
- Birjand University of Medical Sciences
Cirrhosis
Primary Prophylaxis of Gastric Varix Bleed
In patients who have never bled from gastric varix (GOV2 and IGV1), cyanoacrylate injection will be better than both beta-blocker therapy and no treatment in prevention of gastric variceal bleed.
- Trial name
- NCT00905996
- Testing
- Endoscopic cyanoacrylate injection, Beta-blocker (propranolol)
- Where
- India
- Volunteers
- 74 people
- Sponsor
- Govind Ballabh Pant Hospital
Cirrhosis
Beta-blockers for Prevention Of Growth Of Small Esophageal Varices In Cirrhosis: An Randomized Controlled Trial (RCT)
Background and Aims: The efficacy of portal pressure reduction by beta blockers for the management of small (≤5 mm) esophageal varices in patients of cirrhosis is not clear.
- Trial name
- NCT00772057
- Testing
- Propranolol
- Where
- India
- Volunteers
- 164 people
- Sponsor
- Govind Ballabh Pant Hospital
Kaposi Sarcoma
A Study of Propranolol to Treat Kaposi Sarcoma
A clinical study of propranolol for the treatment of Kaposi Sarcoma in children and adults. This study will be an open-label single armed treatment trial that will test the effectiveness and the safety of treating Kaposi Sarcoma…
- Trial name
- NCT05797662
- Testing
- Propranolol
- Where
- 6 sites in Argentina, Brazil and 3 more
- Volunteers
- 25 people
- Sponsor
- AIDS Malignancy Consortium
Critical Illness, Brain Injuries
Neurocognitive Impairment in Pediatric Patients With Meningoencephalitis and Sepsis-associated Encephalopathy
Neurocognitive impairment is frequently observed in pediatric patients with meningoencephalitis (ME) and sepsis-associated encephalopathy (SAE) which represent two relevant central nervous system (CNS) diseases in pediatric…
- Conditions
- Critical Illness, Brain Injuries, Encephalopathy, Delirium
- Trial name
- NCIPED (NCT04467762)
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- University of Rostock
Pediatric Migraine, Headache Disorders
Propranolol for Pediatric Migraine: A Prospective Clinical Study
This prospective, controlled clinical trial was conducted to evaluate the effectiveness of propranolol compared with structured behavioral therapy in pediatric patients diagnosed with primary migraine according to ICHD-3…
- Trial name
- NCT07180043
- Testing
- Structured Behavioral Therapy, Propranolol
- Where
- Turkey (Türkiye)
- Volunteers
- 178 people
- Sponsor
- Kayseri University
Portal Hypertension
Endoscopic Variceal Ligation (EVL)+ Drugs Versus Endoscopic Variceal Ligation (EVL) Alone For Secondary Prophylaxis
Background: Both endoscopic variceal ligation (EVL) and propranolol are valuable methods for secondary prophylaxis of variceal bleeding. Addition of ISMN to propranolol improves the efficacy of drug therapy.
- Trial name
- Secondary (NCT00766805)
- Testing
- EVL + Propranolol + Isosorbide 5 mononitrate, EVL alone
- Where
- India
- Volunteers
- 177 people
- Sponsor
- Govind Ballabh Pant Hospital
Retinopathy of Prematurity
Safety and Efficacy of Propranolol Eye Drops in Treating Retinopathy of Premature
The aim of the present study is to evaluate the safety and efficacy of propranolol eye drops in preterm newborns with a precocious stage of retinopathy of prematurity (ROP).
- Trial name
- DROP-PROP (NCT02014454)
- Testing
- Propranolol eye drops
- Where
- 2 sites in Italy
- Volunteers
- 23 people
- Sponsor
- Meyer Children's Hospital IRCCS
Autism
Combined Effects of Early Behavioral Intervention and Propranolol on ASD
The purpose of this study is to explore the effects of propranolol in combination with early intensive behavioral intervention on social interaction, and secondarily on language, anxiety, adaptive behaviors, and global function…
- Trial name
- NCT02428205
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Missouri-Columbia
Infantile Hemangioma
Study in Infants With Infantile Hemangioma to Compare Propranolol Gel to Placebo
There is an unsatisfied medical need for a first-line treatment of localized uncomplicated proliferating Infantile Hemangioma with a good benefit/risk profile.
- Trial name
- NCT01512173
- Testing
- propranolol gel
- Where
- 17 sites in France, Poland and 1 more
- Volunteers
- 82 people
- Sponsor
- Pierre Fabre Dermatology