Clinical trials: Propranolol
Pediatric Migraine, Migraine Disorders, Brain
Comorbidity-Based Propranolol Use in Pediatric Migraine
This observational retrospective cohort study aims to identify clinical and biochemical predictors of response to propranolol prophylaxis in pediatric migraine.
- Conditions
- Pediatric Migraine, Migraine Disorders, Brain, Vitamin D Deficiency
- Trial name
- NCT07103031
- Testing
- Behavioral therapy, Propranolol
- Where
- Turkey (Türkiye)
- Volunteers
- 488 people
- Sponsor
- Kayseri University
Pediatric Cancer
Use of Propranolol to Reduce FDG Uptake in Brown Adipose Tissue in Pediatric Cancer Patients PET Scans
This is a single-arm, open-label study to assess the safety and effectiveness of a single dose of oral propranolol in reducing18F-fluorodeoxyglucose (FDG) uptake in brown adipose tissue (BAT) in pediatric oncology patients.
- Trial name
- NCT02165683
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Lars Wagner
Migraine
Zonisamide Versus Propranolol in Migraine
Investigators aim to compare the effect of zonisamide versus propranolol in migraine by assessing the absolute reduction in MMD in each group, the percentage of patients who achieved ≥ 50% reduction in the monthly headache days…
- Trial name
- NCT06361446
- Testing
- Zonisamide 50 MG, Propranolol
- Where
- Egypt
- Volunteers
- 600 people
- Sponsor
- Kafrelsheikh University
Retinopathy of Prematurity
a Prospective Cohort Study for Propranolol Treatment in Retinopathy of Prematurity
The purpose of this study is to evaluate the safety and efficacy of oral/local propranolol in preterm newborns who diagnosed as early phase of retinopathy of prematurity (ROP).
- Trial name
- NCT03038295
- Testing
- Propranolol
- Volunteers
- 100 people
- Sponsor
- Guangdong Women and Children Hospital
Extrusion of Tooth
Oral Propranolol for Reducing Pediatric Dental Patients Anxiety
Evaluating anxiety, heart rate and behavior during dental extractions after oral dose of either Propranolol, Midazolam or a combination of both in uncooperative pediatric patients.
- Trial name
- NCT03388957
- Testing
- Propranolol, Midazolam
- Where
- Syria
- Volunteers
- 60 people
- Sponsor
- Damascus University
Hemangioma
Efficacy and Safety of Propranolol Versus Atenolol on the Proliferative Phase of Infantile Hemangioma
The purpose of this study is to compare the efficacy of orally administered propranolol versus atenolol in the treatment of potentially disfiguring or functionally threatening IHs.
- Trial name
- NCT02342275
- Testing
- Propranolol, Atenolol
- Where
- China
- Volunteers
- 377 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Burn
Fenofibrate and Propranolol in Burn Patients
The proposed study will test the hypothesis that Propranolol, fenofibrate and fenofibrate plus propranolol have therapeutic, physiological, and metabolic effects that will improve clinical outcomes, and the long-term recovery…
- Trial name
- NCT02452255
- Testing
- Fenofibrate, Propranolol
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Postpartum Hemorrhage
In Vitro Optimization of Oxytocin-induced Myometrial Contractility by Propranolol
The rates of cesarean deliveries (CD) and postpartum hemorrhage (PPH) are on the rise, with failed induction and augmentation of labor as major contributing factors.
- Trial name
- NCT03434444
- Testing
- Oxytocin, Propranolol
- Where
- Canada
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Propranolol, Labour Induction
Effects of Oral Propranolol on Induction-Delivery Interval During Induction of Labour With Oxytocin
Prolonged pregnancy could lead to perinatal and maternal complications. Oxytocin has been wildly used for induction of labour, but prolonged labour continued to occur with its attendant sequelae.
- Trial name
- NCT06960850
- Testing
- Propranolol
- Where
- Nigeria
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- Federal Teaching Hospital Abakaliki
Cirrhosis
Secondary Prophylaxis Gastric Variceal Bleed
The investigators conducted a randomized, controlled trial (RCT) to study the efficacy of beta blockers versus endoscopic cyanoacrylate injection in the prevention of gastric variceal (GOV2 or IGV1) rebleeding and improvement in…
- Trial name
- NCT00888784
- Testing
- Endoscopic Cyanoacrylate injection, beta-blocker (propranolol)
- Where
- India
- Volunteers
- 64 people
- Sponsor
- Govind Ballabh Pant Hospital
Hemangioma, Propranolol
Role of Propranolol as Compared to Bleomycin in Management of Hemangioma
Infantile hemangiomas are widespread vascular tumours having incidence of 10% and most of them involute spontaneously. However, they are known to be located in proximity of vital organs and can have poor cosmetic and functional…
- Trial name
- NCT05327309
- Testing
- Bleomycin
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
Postural Orthostatic Tachycardia Syndrome
Effect of Medical Treatment and Prognosis of Postural Orthostatic Tachycardia Syndrome (POTS)
The purpose of the study is to investigate effect of medical treatment and prognosis of Postural Orthostatic Tachycardia Syndrome (POTS)
- Trial name
- POTS (NCT02171988)
- Testing
- Propranolol, Bisoprolol, Propranolol+pyridostigmine
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Seoul National University Hospital
Autism
Trial of Propranolol in Adults and Adolescents With ASD and Predictors of Response
The purpose of this study is to explore the effects of propranolol on social interaction, and secondarily on language, anxiety, adaptive behaviors, and global function in high functioning adults and adolescents with autism in a…
- Trial name
- NCT02414451
- Testing
- Propranolol
- Sponsor
- University of Missouri-Columbia
Infantile Hemangioma (IH)
Low-Dose Propranolol and Bleomycin for Infantile Hemangioma (IH)
This is a prospective, randomized controlled trial designed to evaluate the efficacy and safety of low-dose oral propranolol (1 mg/kg/day) combined with monthly intralesional bleomycin injections versus low-dose propranolol…
- Trial name
- NCT07104526
- Testing
- Propranolol + Bleomycin, Propranolol
- Where
- China
- Volunteers
- 260 people
- Sponsor
- Wuhan Integrated Traditional Chinese and Western Medicine Hospital
Diabetes Mellitus, Type 1, Inflammation
The Role of the Adrenergic System in Hypoglycaemia Induced Inflammatory Response in People With Type 1 Diabetes and People Without Type 1 Diabetes-RAID-II
The goal of this trial is to study the effect that adrenaline has on the immune reaction seen during a low blood sugar. People with type 1 diabetes do not produce their own insulin.
- Trial name
- RAID-II (NCT06422494)
- Testing
- hyperinsulinaemic hypoglycaemic clamp, Propranolol Hydrochloride 1 MG/ML, Phentolamine
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Burn
Propranolol in Severely Burned Children
To determine the safety and efficacy of administration of propranolol for reducing heart rate and blood pressure in burn injury.
- Trial name
- NCT01957449
- Testing
- Propranolol
- Where
- 4 sites in United States
- Volunteers
- 63 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Pain Measurement
Evaluation of Propranolol's Effect on Pain and Inflammation.
Previous studies have shown that the beta-adrenergic system plays a role in processing pain and the expression of hyperalgesia. Recent studies have investigated the analgesic effects, and potential anti-hyperalgesic effects…
- Trial name
- NCT01094574
- Testing
- Alfentanil, Propranolol
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Martin Angst
Hemangioendothelioma of Liver
Sirolimus in the Treatment for Infantile Hepatic Hemangioendothelioma(IEEH)
Infantile hepatic hemangioendothelioma (IHHE) is an infantile hemangioma involving the liver.Since 2008, propranolol has been used for the treatment of hemangioma, and some researchers have also started to report the use of…
- Trial name
- PRL-SRL-IHHE (NCT04406870)
- Testing
- Sirolimus Oral Product, propranolol
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Shanghai Children's Medical Center
Infantile Hemangioma
Evaluation of the Efficacy of Captopril Versus Propranolol and Timolol as a Treatment of Infantile Capillary Hemangioma
Is to compare and evaluate the efficacy of oral captopril with oral propranolol, intralesional propranolol injection, and topical Timolol in the treatment of infantile hemangioma and their effect on vascular endothelial growth…
- Trial name
- NCT04288700
- Testing
- oral propranolol, Oral Captopril, intralesional propranolol injection
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Induction of Labor Affected Fetus / Newborn
A Comparison Between the Effect of Oxytocin Only and Oxytocin Plus Propranolol on Induction of Labor in Term Pregnancy
The present study is conducted to compare the effect of Oral Propranolol and Oxytocin, versus Oxytocin only on induction of labor in term pregnancy.
- Trial name
- NCT03533699
- Testing
- Propranolol
- Where
- Egypt
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital