Clinical trials: Sevoflurane
Sedation for Children Undergoing MRI
A Comparison Between Oral Melatonin With Nasal Sevoflurane Versus Oral Chloral Hydrate With Nasal Sevoflurane in Sedation of Children Undergoing Brain MRI
The patients will be randomized into 2 equal groups by a computer-generated random numbers table, named group A, B. Group A: will receive oral Melatonin and nasal Sevoflurane.
- Trial name
- NCT06606899
- Testing
- Melatonin 3 MG, Chloral Hydrate, Sevoflurane
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Airway Complication of Anesthesia
Effects of Propofol on Respiratory Adverse Events During Extubation in Children Undergoing Tonsil Adenoidectomy
The main objective of this study was to investigate whether propofol assisted extubation could reduce the incidence of respiratory adverse events in children with tonsil adenoidectomy.
- Trial name
- NCT05769842
- Testing
- propofol, normal saline
- Where
- China
- Volunteers
- 239 people
- Sponsor
- Children's Hospital of Fudan University
Adenotonsillectomy, Postoperative Pain
Correlation Between Pain and Emergence Delirium After Adenotonsillectomy in Preschool Children
The purpose of this study is to determine the incidence of pain, emergence delirium and the combination of those postoperative negative behaviours during the first 15 minutes after awakening from sevoflurane anesthesia in…
- Conditions
- Adenotonsillectomy, Postoperative Pain, Emergence Delirium
- Trial name
- e-PONB ENT (NCT01096797)
- Testing
- Sevoflurane
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- San Gerardo Hospital
Obstructive Sleep Apnea
Fentanyl Test and A Short OSAS Screening Scale for Severe Obstructive Sleep Apnea
The aim of this study was to estimate and compare the value of the preoperative fentanyl test and the short OSAS screening scale to diagnose severe obstructive sleep apnea；and to observe the required amount of hydromorphone and…
- Trial name
- NCT03705780
- Testing
- the short OSAS scale, fentanyl test
- Where
- China
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Child, Only, Temperature Regulation; Disorder
Effect of Sevoflurane on Sweat Threshold in Children of Different Ages
Hypothermia is a common complication in pediatric anesthesia. Hypothermia will prolong the recovery time of anesthesia, and may also lead to increased oxygen consumption, prolonged blood coagulation time, and affect the…
- Conditions
- Child, Only, Temperature Regulation; Disorder, Low Body Temperatures, Sevoflurane
- Trial name
- NCT07035782
- Testing
- temperature monitoring, Sevoflurane
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Obstructive Sleep Apnea
Dexmedetomidine Versus Propofol Sedation for Drug-Induced Sleep Endoscopy in Pediatric Obstructive Sleep Apnea
This research study is designed to learn, first, whether two anesthetics have different effects on collapse seen within the upper airway during sleep endoscopy.
- Trial name
- NCT05303987
- Testing
- Propofol sedation, Dexmedetomidine sedation
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Erin Kirkham
Pain Measurement, Newborn
Interest of Using the Sevoflurane in the Prevention of Newborns Pain
The objective of this randomized and controlled study is to compare the sedation with sevoflurane inhalation versus non-nutritive sucking and sucrose administration to facilitate peripheral inserted central catheter insertion in…
- Trial name
- NCT00420693
- Testing
- sevoflurane
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Sevoflurane Consumption
Pre-emptive Local Anesthesia and Sevoflurane Consumption in Pediatric Dental Anesthesia
This study will evaluate whether pre-emptive local anesthesia reduces sevoflurane consumption during pediatric day-case dental treatment performed under general anesthesia.
- Trial name
- PEDSEVOLA (NCT07608900)
- Testing
- Pre-emptive Local Anesthesia, Articaine With Epinephrine, Sevoflurane
- Volunteers
- 80 people
- Sponsor
- TC Erciyes University
Neuromuscular Blocking Agents, Residual Neuromuscular Block
Measuring of the Duration of Action of Different Doses of Rocuronium-induced Neuromuscular Block in Infants During Surgical Treatment of Craniosynostosis
The use of intravenous muscle relaxants during anaesthesia can significantly facilitate endotracheal intubation and reduce the chance of possible airway complications during intubation.
- Conditions
- Neuromuscular Blocking Agents, Residual Neuromuscular Block, Neuromuscular Blockade Monitoring
- Trial name
- NCT07080528
- Testing
- Sevofluorane, Propofol
- Where
- Hungary
- Volunteers
- 20 people
- Sponsor
- Tamas Vegh, MD
Anesthesia
Neurodevelopment Outcomes After Pediatric Dental Caries Treatment Under General Anaesthesia
The purpose of this study is to investigate whether early expose to general anaesthesia will influence neurodevelopment.
- Trial name
- NCT03002792
- Testing
- general anesthesia
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Air Force Military Medical University, China
Liver Transplantation, Children
Anaesthetic and Pediatric Living Related Liver Transplantation
To study the effect of different anaesthetic methods on pediatric neurocognitive development and cerebral injury during pediatric living related liver transplantation .
- Trial name
- NCT03024840
- Testing
- Sevoflurane, Propofol
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Tianjin First Central Hospital
Anesthesia, Electroencephalography/ Drug Effect
Detection of Consciousness by EEG and Auditory Evoked Potentials
The objective of the present investigation is to analyze EEG and auditory evoked potentials at the transition from consciousness to unconsciousness and vice versa.
- Trial name
- NCT01720615
- Testing
- Propofol / Remifentanil, Sevoflurane / Remifentanil
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Technical University of Munich
Pain, Postoperative, Agitation States as Acute Reaction to Exceptional Stress
Gabapentin as Preanesthetic Medication to Fast Procedures in Pediatric´s Oncology
This study is a clinical trial, prospective, randomized and double-blinded. Placebo, Gabapentin syrup at 15 mg/kg, and Gabapentin syrup at 30 mg/kg were administered to reduce agitation before and after in children submitted…
- Conditions
- Pain, Postoperative, Agitation States as Acute Reaction to Exceptional Stress, Anesthesia, Vomiting
- Trial name
- NCT03681574
- Testing
- GABA 15mg/kg Group, GABA 30mg/kg Group
- Where
- Brazil
- Volunteers
- 135 people
- Sponsor
- Hospital Infantil Albert Sabin
Chalazion
Effect of Different Concentrations of Sevoflurane for Anesthesia Induction in Pediatric Ophthalmic Surgery
This randomized controlled trial aims to compare the effectiveness and safety of 6% versus 8% sevoflurane inhalation induction in pediatric patients undergoing minor ophthalmic surgery.
- Trial name
- SEVO-PED (NCT07450495)
- Testing
- Sevoflurane
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong
Delirium, Psychomotor Agitation
Acupuncture for the Prevention of Emergence Delirium in Children Undergoing Myringotomy Tube Placement
Myringotomy tube placement is one of the most commonly performed operations in children. Emergence delirium after such procedures is common.
- Trial name
- NCT02383004
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Oregon Health and Science University
Intraocular Pressure
Effect of Sevoflurane Concentration on Intraocular Pressure in Surgical Children With Healthy Eyes
One important goal in anesthetic management during ocular surgery is to provide adequate control of intraocular pressure (IOP). An increase in IOP may be catastrophic in patients with glaucoma or a penetrating open-eye injury.
- Trial name
- NCT01248689
- Testing
- concentration profile 1, concentration profile 2, concentration profile 3
- Where
- Israel
- Volunteers
- 21 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Craniotomy Surgery, Pediatric Patient Safety
The Effect Of Positive End-Expiratory Pressure on Optic Nerve Sheath Diameter In Pediatric Patients Undergoing Craniotomy in Supine Position
This study evaluated the effect of positive end-expiratory pressure (PEEP) on optic nerve sheath diameter (ONSD), an indicator of intracranial pressure, in pediatric patients undergoing craniotomy in the supine position.
- Conditions
- Craniotomy Surgery, Pediatric Patient Safety, Pediatric Patient, Positive End-expiratory Pressure (PEEP)
- Trial name
- NCT07370779
- Testing
- General Anesthesia, Anesthetic Agents, mechanical ventilation (MV)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Heart Defects, Congenital
DEX vs SEVO in Congenital Heart Surgery
Anesthesia-related neurotoxicity in the developing brain is still a concern although evidence in humans is debatable. Moreover, it is unclear whether repeated and/or prolonged exposures are harmless and whether their effects are…
- Trial name
- DEXLOSNeuro (NCT05369949)
- Testing
- DEX group, Control group
- Volunteers
- 150 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Delirium
Different Doses of Sevoflurane During Induction of Anesthesia on Emergence Delirium in Children
The investigators aim to reduce the incidence of emergence delirium in children aged 2-7 years old by using two different doses of sevoflurane during inhalatory induction of anesthesia.
- Trial name
- NCT02707016
- Testing
- Sevoflurane 8%, Sevoflurane 5%
- Where
- Chile
- Volunteers
- 80 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Biliary Atresia
Biliary Atresia, Hepatic Buffer Response and Sevoflurane
To evaluate the effects of sevoflurane on hepatic blood flow (HBF) and hepatic arterial buffer response (HABR) in infants with obstructive jaundice by Doppler ultrasound.Twenty-five infants with biliary atresia (1-3…
- Trial name
- NCT02471209
- Testing
- Sevoflurane
- Volunteers
- 25 people
- Sponsor
- Children's Hospital of Fudan University