Clinical trials: Transcranial Direct Current Stimulation
Neurofibromatosis 1
Non-invasive Stimulation in Neurofibromatosis Type 1
Intellectual impairments are a significant cause of morbidity in children with birth defects along with long term implication on academic and occupational functioning.
- Trial name
- tDCS is NF1 (NCT03310996)
- Testing
- Transcranial direct current stimulation
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- University of Manchester
Childhood Onset Dystonias
Transcranial Direct-Current Stimulation in Childhood Dystonia
The investigators hypothesize that transcranial direct current stimulation over the motor cortex will reduce muscle overflow and improve hand function in children with primary or secondary dystonia.
- Trial name
- NCT01460771
- Testing
- TDCS (Transcranial Direct-current Stimulation)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Southern California
Subthreshold Depression, Young People
TDCS Interventions for Subthreshold Depressive Symptoms in Young Individuals.
The purpose of this study is to assess the mechanisms of the effect of transcranial direct current stimulation (tDCS) in alleviating subthreshold depressive symptoms in young individuals, and individualized outcome prediction is…
- Conditions
- Subthreshold Depression, Young People, Transcranial Direct Current Stimulation
- Trial name
- NCT06294184
- Testing
- tdcs lDLPFC, tdcs rVLPFC
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Guangzhou Psychiatric Hospital
Cerebral Palsy
Integrated Management Enhances Functional Gains in Children With Cerebral Palsy Treated by BoNT-A
Evidence from literature support the use of Botulinum toxin A (BoNT-A) for upper limb spasticity management in children with cerebral palsy (CP).
- Trial name
- NCT03302871
- Testing
- Botulinum toxin type A, transcranial direct current stimulation, hybrid training model of CIMT and BIT
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Kocaeli University
PARKINSON DISEASE (Disorder), Parkinson Disease
Effect of Repetitive Bihemispheric Anodal Transcranial Direct Current Stimulation on Motor Function of Patients With Parkinson's Disease
Dopaminergic medications and Deep Brain Stimulation (DBS) are the current standards interventions for Parkinson's Disease. Pharmacotherapy with dopaminergic drugs leads to partial improvement in motor functions of patients.
- Trial name
- NCT07395531
- Testing
- Transcranial Direct Current Stimulation
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Dr. Ram Manohar Lohia Hospital
Transcranial Direct Current Stimulation, Autistic Disorders Spectrum
Transcranial Direct Current Stimulation in Autism Spectrum Disorder
Background: Transcranial Direct Current Stimulation (tDCS) is a form of non-invasive brain stimulation that has aroused increased interests in the past decade.
- Conditions
- Transcranial Direct Current Stimulation, Autistic Disorders Spectrum, Electroencephalography
- Trial name
- NCT03814083
- Testing
- Active-tDCS, Wait-list
- Where
- Hong Kong
- Volunteers
- 105 people
- Sponsor
- The Hong Kong Polytechnic University
Transcranial Alternating Current Stimulation, Non-suicidal Self-injury
Intervention Effect of High-Definition Transcranial Alternating Current Stimulation (HD-tACS) on Non-suicidal Self-injury (NSSI)
To investigate the intervention effect of high-definition transcranial alternating current stimulation (HD-tACS) on patients with Non-suicidal Self-injury (NSSI) and its underlying neural mechanism by magnetic resonance imaging…
- Trial name
- NCT06127056
- Testing
- High-Definition Transcranial Alternating Current Stimulation (HD-tACS)
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Anhui Medical University
Cerebral Palsy (CP)
Pediatric Teleneuromodulation
This study will explore using remotely monitored 'active' non-invasive brain stimulation in children with cerebral palsy. Participants will receive active non-invasive brain stimulation with synchronous safety monitoring and…
- Trial name
- NCT05071586
- Testing
- Soterix 1x1 tDCS LTE Stimulator Device Model 1401
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Wisconsin, Madison
Anorexia Nervosa
Cerebellar tDCS Stimulation in Children and Adult Women With Anorexia Nervosa Disorder
Hypothesis: Will the use of tDCS brain modulation in the cerebellum assist in restricted behaviors, social cognition and cognitive flexibility in women with anorexia nervosa in addition to other therapies? Primary Outcomes: 1.
- Trial name
- NCT06286930
- Testing
- anodal trans cranial direct current stimulation (tDCS), cathodal trans cranial direct current stimulation (tDCS)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Texas Southwestern Medical Center
Spastic Diplegic Cerebral Palsy
Effects of Transcranial Direct Current Stimulation Combined With Virtual Reality on Balance and Executive Functions in Children With Spastic Diplegic Cerebral Palsy
Children with spastic diplegic cerebral palsy commonly experience difficulties with balance and may also have challenges involving attention, working memory, cognitive flexibility, and inhibitory control.
- Trial name
- NCT07829770
- Testing
- Active Transcranial Direct Current Stimulation, Virtual Reality Rehabilitation, Conventional Physical Therapy
- Where
- 2 sites in Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Parkinsons Disease (PD)
Transcranial Direct Current Stimulation for Motor Function and Fatigue in PD
The investigators hypothesize that multi-session anodal tDCS (atDCS) of the left primary motor cortex (M1) will induce long-lasting effects in improving motor function and reducing motor fatigue and fatigability in PD patients.
- Trial name
- tDCS (NCT06883266)
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Sanford Health
Developmental Coordination Disorder
Does tDCS Improve Motor Learning in Children With DCD?
Transcrainial direct current stimulation (tDCS) has become increasingly popular over the past decade. tDCS is a safe and well-studied form of non-invasive brain stimulation.
- Trial name
- NCT03453983
- Testing
- Transcrainial Direct Current Stimulation (tDCS)
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- University of Calgary
Autism Spectrum Disorder
Targeting Repetitive Behaviors in Autism Spectrum Disorder Via Transcranial Direct Current Stimulation
Repetitive behaviors (RBs) are a prevalent feature of Autism Spectrum Disorder (ASD). There are two groups of RBs: lower-order (e.g. motor stereotypies) and higher-order RBs (e.g.
- Trial name
- NCT06645587
- Testing
- Active HD-tDCS over pre-SMA, Active HD-tDCS over left DLPFC
- Where
- Italy
- Volunteers
- 78 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Healthy Adults
The Effects of Transcranial Direct Current Stimulation Combined With Resistance Training on Motor Learning in Healthy Young Adults
This study aimed to investigate whether six weeks of tDCS combined with lower-limb resistance training could enhance motor learning in healthy young adults and examined the persistence of any observed benefits.
- Trial name
- NCT07092098
- Testing
- tDCS combined with resistance training, Resistance training, tDCS
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
Bone Sarcoma, Childhood Cancer
Culturally Adapted Mobile Treatment of Chronic Pain in Adolescent Survivors of Pediatric Cancer
This is a prospective study that will conduct a series of focus groups with non-Hispanic Black and Hispanic childhood cancer survivors to obtain their input on culturally adapting a mobile CBT program for chronic pain and tDCS…
- Trial name
- NCT05746429
- Testing
- Cognitive Behavior Therapy, Transcranial Direct Current Stimulation, Questionnaire Administration
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Parkinson Disease, Mild Cognitive Impairment
Non-invasive Brain Stimulation for the Treatment of Mild Cognitive Impairment in Parkinson's Disease
This cross-over pilot study aims to study the acceptability of two methods of non-invasive brain stimulation for the treatment of Parkinson's disease mild cognitive impairment (PD-MCI) - repetitive transcranial magnetic…
- Trial name
- NESCIO-PD (NCT06399731)
- Testing
- High-frequency (10Hz) rTMS, Anodal tDCS
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Amsterdam UMC
Epilepsy
Transcranial Direct Current Stimulation (tDCS) As A Tool For Prospective Responder Identification Before Vagus Nerve Stimulation (VNS) Implantation
The aim of the study is to establish tDCS as a prognostic tool to predict VNS therapy outcome among patients with pharmacoresistant epilepsy.
- Trial name
- NCT00625222
- Testing
- transcranial direct current stimulation
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- University of Luebeck
Acute Migraine
Transcranial Direct Current Stimulation for Migraine Attack
This study is conducted to investigate the therapeutic efficacy and safety of transcranial direct current stimulation (tDCS) over the primary motor cortex of patients with acute migraine attack.
- Trial name
- NCT01358279
- Testing
- transcranial direct current stimulation
- Where
- South Korea
- Volunteers
- 32 people
- Sponsor
- Seoul National University Hospital
Cerebral Palsy, Perinatal Stroke
Single-session tDCS in Cerebral Palsy
The goal of this study is to characterize individual responses to a single application of transcranial direct current stimulation (tDCS) in children with unilateral cerebral palsy (UCP), and to test which electrode configuration…
- Conditions
- Cerebral Palsy, Perinatal Stroke, Periventricular Leukomalacia
- Trial name
- NCT03635775
- Testing
- Active tDCS
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Down Syndrome
Non-Invasive Brain Stimulation to Improve Language in Down Syndrome.
Down syndrome (DS) is associated with cognitive deficits, caused by alterations in neuroplasticity and synaptic transmission. Non-invasive brain stimulation techniques, such as transcranial direct current stimulation (tDCS), can…
- Trial name
- NCT07044804
- Testing
- Active Group (Active Anodal tDCS to the left IFG or Cathodal tDCS to the left IFG)
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Floriana Costanzo