Clinical trials: rTMS
Major Depressive Disorder (MDD)
Electroencephalography-based Precise Repetitive Transcranial Magnetic Stimulation Treatment
This study will focus on the hypothesis that repetitive transcranial magnetic stimulation (TMS) based on EEG personalized modulation may be more effective in promoting symptomatic relief of major depressive disorder (MDD), and…
- Trial name
- NCT06385405
- Testing
- Individualized alpha frequency Transcranial Magnetic Stimulation (αTMS) Treatment, 10Hz-frequency TMS treatment over the left dorsolateral prefrontal cortex (DLPFC)
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Shanghai Mental Health Center
Autism Spectrum Disorder, ADHD
Therapeutic Use of rTMS in Pediatric ASD and ADHD Cohorts
In this interventional, pilot clinical trial investigators will stimulate the dorsolateral prefrontal cortex (DLPFC) in patients with Autism and ADHD.
- Conditions
- Autism Spectrum Disorder, ADHD, Neurodevelopmental Disorders
- Trial name
- NCT06069323
- Testing
- repetitive Transcranial Magnetic Stimulation
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ospedali Riuniti di Foggia
Autism Spectrum Disorder
Efficacy and Mechanism of Repetitive Transcranial Magnetic Stimulation in Children With Autism Spectrum Disorders
This study is a prospective, multicenter, randomized, single-blind controlled trial to enroll 200 children with autism spectrum disorders (ASD).
- Trial name
- NCT05927792
- Testing
- repeated transcranial magnetic stimulation (continuous theta-burst stimulation)
- Where
- 3 sites in China
- Volunteers
- 200 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Clinical High-risk Syndrome of Psychosis
RTMS for CHR Based on Personalized Targets Using Magnetoencephalography
This study is an before-after study in the same subject, which enrolled 26 individuals with high-risk psychiatric syndrome (CHR). The target of subjects intervention relies on the results of magnetoencephalography localization.
- Trial name
- NCT06802952
- Testing
- rTMS
- Where
- China
- Volunteers
- 26 people
- Sponsor
- Shanghai Mental Health Center
Major Depressive Disorder
Transcranial Magnetic Stimulation for Adolescent Depression
Major depression (or MDD) in adolescents is a major public health problem. MDD affects approximately 15% of adolescents; it is associated with impairment in social, family, and academic functioning, and it is a major risk factor…
- Trial name
- TMSAD (NCT01731678)
- Testing
- Transcranial Magnetic Stimulation
- Where
- Canada
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Depression, Electroencephalography
Intermittent Theta Burst Stimulation on Anhedonia in Depression
Study comparing the efficacy of two TMS patterns (intermittent theta-burst stimulation, iTBS, and repetitive transcranial magnetic stimulation, rTMS) in treating anhedonia and their associated brain network mechanisms.
- Conditions
- Depression, Electroencephalography, Transcranial Magnetic Stimulation
- Trial name
- NCT06552026
- Testing
- repeated transcranial magnetic stimulation
- Where
- China
- Volunteers
- 33 people
- Sponsor
- Anhui Medical University
Parkinson Disease With Freezing of Gait
Effects of Neuromodulation and Rehabilitation of the Locomotor Network in Freezing of Gait
Freezing of gait (FoG) is a common and debilitating condition in Parkinson's Disease (PD) patients. FoG is described as an episodic inability to walk, which often triggers falls, hospitalization and is an important predictor of…
- Trial name
- TMS/FOG (NCT03273270)
- Testing
- transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
Movement Disorders, Parkinson Disease
Transcranial Magnetic Stimulation for the Treatment of Parkinson's Disease
The problems in motor activity associated with Parkinson's disease are still poorly understood. Patients with Parkinson's disease often suffer from extremely slow movements (bradykinesia) which result in the inability to perform…
- Trial name
- NCT00001665
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Autism
Therapeutic Intervention Effects of rTMS on Children With Autism Spectrum Disorder
Autism spectrum disorder (ASD) is a common and complex neurodevelopmental disorder, which is characterized by impairments of social communication, social reciprocity, as well as restricted and repetitive behaviors (RRB).
- Trial name
- NCT05140356
- Testing
- Applied high amplitude repeated transcranial magnetic stimulation, Applied low amplitude repeated transcranial magnetic stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- University of Electronic Science and Technology of China
Cannabis Use, Cannabis Use Disorder
Transcranial Magnetic Stimulation for Adolescents and Young Adults With Cannabis Use Disorder
This pilot study will investigate the potential of repetitive transcranial magnetic stimulation (rTMS) to strengthen a neural circuit critical for maintaining abstinence in adolescents and youth with cannabis use disorder (CUD).
- Trial name
- NCT07634835
- Testing
- Magstim SuperRapid2
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Minnesota
Schizophrenia
rTMS for Auditory Hallucinations Guided by Magnetoencephalography
rTMS and MEG for auditory hallucinations via self controlled clinical trials. Repetitive transcranial magnetic stimulation (rTMS) can increase or decrease cortical excitability in patients with psychosis (such as schizophrenia).
- Trial name
- NCT05598450
- Testing
- rTMS and MEG for auditory hallucinations via self controlled clinical trials
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Mental Health Center
Schizophrenia
Repetitive Transcranial Magnetic Stimulation for First-episode Schizophrenia Patients
The aim of the study is to evaluate the effects of repetitive transcranial magnetic stimulation(rTMS)in the first-episode Schizophrenic patients: the clinical and MRI findings
- Trial name
- rTMSfMRI (NCT01370291)
- Testing
- active Risperidone and active rTMS
- Where
- 2 sites in China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Depression - Major Depressive Disorder
Feasibility, Safety, and Preliminary Clinical Efficacy of Magnetic Resonance Imaging-guided Repetitive Transcranial Magnetic Stimulation (rTMS) in Adolescents With Depression: A Randomized, Double-Blind, Controlled Pilot Study
This study aims to assess the feasibility, safety, acceptability, and preliminary efficacy trends of a Magnetic Resonance Imaging-guided Repetitive Transcranial Magnetic Stimulation (rTMS) intervention for adolescent depression…
- Trial name
- NCT07185438
- Testing
- Experimental target rTMS treatment, Conventional target rTMS treatment
- Where
- China
- Volunteers
- 45 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Major Depressive Episode
Personalized Repetitive Transcranial Magnetic Stimulation Treatment for Major Depressive Episode
Adolescents and young adults with mood disorders experiencing major depressive episode have poor efficacy of medication treatment.
- Trial name
- PRTMSTMDEAYA (NCT05465928)
- Testing
- Active rTMS
- Where
- China
- Volunteers
- 219 people
- Sponsor
- Jiangsu Province Nanjing Brain Hospital
Autism Spectrum Disorder, Major Depressive Disorder
rTMS for Depression in Young Adults With Autism
The current clinical trial is focused on evaluating the efficacy of rTMS for treatment of depression in youth and young adults (hereafter called transition aged youth, TAY) with autism spectrum disorder (ASD).
- Trial name
- rTMS-MDD (NCT04972136)
- Testing
- Active Bilateral Theta Burst Stimulation
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Centre for Addiction and Mental Health
Treatment Resistant Depression
Linear Asymmetric rTMS in Adolescent Treatment-Resistant Depression: Treatment Durations From Ten Days to One Day
This is a pilot interventional study to investigate the acceptability, tolerability, and side effect profile for varying numbers of treatment sessions/day of a new rTMS treatment in adolescents with treatment-resistant depression…
- Trial name
- NCT03986658
- Testing
- Linear Asymmetric rTMS System
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- NeuroQore Inc.
Major Depressive Disorder (MDD), Depression - Major Depressive Disorder
Efficacy and Safety of a Theta Burst Stimulation Protocol of Repetitive Transcranial Magnetic Stimulation in Treatment-Resistant Depression
This study will evaluate the efficacy and safety of a theta burst stimulation (TBS) protocol of repetitive transcranial magnetic stimulation (rTMS) in adults with treatment-resistant depression.
- Trial name
- NCT07529574
- Testing
- antidepressant therapy, Active rTMS Theta Burst Stimulation
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Jung-Sun Lee
Major Depressive Disorder
rTMS for Depressed Teens: A Sham-Controlled Trial, Part 1
This research proposal aims to better understand the neurobiology of depression in adolescents and how repetitive transcranial magnetic stimulation (rTMS) may therapeutically impact brain function and mood.
- Trial name
- NCT01804270
- Testing
- Repetitive transcranial magnetic stimulation (rTMS)
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Paul E. Croarkin
Alzheimer s Disease, Alzheimer Dementia (AD)
Combined Brain Stimulation and Methylphenidate Treatment for Apathy in Dementia
This study evaluates whether the combined treatment of methylphenidate and non-invasive brain stimulation, called intermittent theta burst stimulation, can effectively treat apathy in individuals with Alzheimer's disease or mixed…
- Conditions
- Alzheimer s Disease, Alzheimer Dementia (AD), Alzheimer Dementia, Alzheimer Disease
- Trial name
- PRIME (NCT07279740)
- Testing
- intermittent theta burst stimulation (iTBS), Methylphenidate (MPH)
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Sunnybrook Health Sciences Centre
Disorder of Consciousness
Transcranial Magnetic Stimulation in Patients With Disorders of Consciousness
Transcranial magnetic stimulation involves the use of alternating magnetic fields to stimulate neurons in the brain.To date, several studies have focused on the use of TMS in patients with impaired consciousness.However,its…
- Trial name
- NCT03385278
- Testing
- rTMS
- Where
- China
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University