Clinical trials: sponsored by Beijing Friendship Hospital
Cataract, Vitreous Hemorrhage
Study on Eye-Brain Cross-Organ Mapping and Systemic Disease Association Based on Multimodal Big Data
This project integrates multimodal eye data (CFP, OCT, OCTA) from 50,000 cases, brain MR data from 150,000 cases, and ICD diagnoses, medical orders, and test results from an eye-brain paired cohort of 8,000 cases to construct an…
- Conditions
- Cataract, Vitreous Hemorrhage, Diabetic Eye Diseases, Cerebral Small Vessel Disease
- Trial name
- NCT07541651
- Testing
- No interventions were involved in this study.
- Volunteers
- 208,000 people, healthy volunteers welcome
- Sponsor
- Beijing Friendship Hospital
Invasive Mold Diseases
Safety and Efficacy of Liposomal Amphotericin B for Patients With Invasive Mold Diseases in Liver Transplant Recipients
Invasive mold diseases (IMD) carry extremely high mortality rates in liver transplant recipients (aspergillosis prevalence ~1.8%, mortality 60%-90%; mucormycosis prevalence ~2%, mortality 38%-95%).
- Trial name
- NCT07725874
- Testing
- AmBisome (Amphotericin B) Liposome
- Volunteers
- 60 people
- Sponsor
- Beijing Friendship Hospital
Drug-induced Liver Injury, Autoimmune Hepatitis
Discrimination of DILI and AIH by Artificial Intelligence
A retrospective, multi-center, non-interventional cohort study has been going to explore whether artificial intelligence can discriminate Drug-induced liver injury and Autoimmune hepatitis.
- Trial name
- NCT05532345
- Where
- China
- Volunteers
- 2,583 people
- Sponsor
- Beijing Friendship Hospital
Chronic Diseases, Sub-optimal Health
Real-World Data Linkage Research Platform
This study aims to address the lack of intelligent governance tools in clinical data management to promote efficient governance and secure sharing of real-world health data.
- Trial name
- NCT07635355
- Testing
- This is an observational study. No intervention will be applied.
- Where
- China
- Volunteers
- 300,000 people, healthy volunteers welcome
- Sponsor
- Beijing Friendship Hospital
Liver Failure, Small-for-Size Syndrome
Safety and Tolerability Study of a Novel Bioartificial Liver in Liver Failure and Small-for-Size Syndrome
The goal of this clinical trial is to evaluate the safety and tolerability of a novel bioartificial liver (CiPS-BAL) in patients with liver failure or small-for-size syndrome.
- Trial name
- NCT07312864
- Testing
- Chemically induced pluripotent stem cells biological Artificial Liver
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Beijing Friendship Hospital
Sub-healthy
Data Mining of Population Health-sub-health-disease Based on Dynamic System Theory
This study aims to explore the dynamic evolution patterns of population health, sub-health, and disease states through dynamic system theory and big data mining methods, providing scientific evidence for personalized prevention…
- Trial name
- NCT07375303
- Testing
- No intervention will be applied.
- Where
- China
- Volunteers
- 380,000 people, healthy volunteers welcome
- Sponsor
- Beijing Friendship Hospital
Lymphohistiocytosis, Hemophagocytic
Prospective Single-Arm Clinical Trial of GO Regimen for HLH.
This study aims to investigate the efficacy and safety of Golidocitinib(GO) monotherapy in the treatment of hemophagocytic lymphohistiocytosis.
- Trial name
- NCT07339345
- Testing
- Golidocitinib
- Where
- China
- Volunteers
- 28 people
- Sponsor
- Beijing Friendship Hospital
Mycoplasma Pneumoniae Pneumonia
Development and Validation of an Early Prediction Model for Severe Mycoplasma Pneumoniae Pneumonia in Children
Pneumonia is a major threat to the health of children. Mycoplasma pneumoniae infection is a core cause of pediatric pneumonia, and the incidence of severe mycoplasma pneumoniae pneumonia (SMPP) has increased in recent years.
- Trial name
- NCT07333833
- Testing
- medical history taking, blood test, pulmonary ultrasound
- Where
- China
- Volunteers
- 964 people
- Sponsor
- Beijing Friendship Hospital
Primary Biliary Cholangitis (PBC), Long-term Outcomes
PBC Long-term Outcomes Study
Primary biliary cholangitis (PBC) is an autoimmune liver disease predominantly affecting middle-aged women. While historically it was deemed rare, advancements in specific auto-antibody tests have led to increased recognition of…
- Conditions
- Primary Biliary Cholangitis (PBC), Long-term Outcomes, Prognosis, Multicenter Prospective Study
- Trial name
- NCT07149675
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Beijing Friendship Hospital
Gastric Cancer
Plasma Metabolic Biomarkers for Gastric Cancer Diagnosis
The aim of this observational study is to comprehensively analyze the metabolites in plasma samples from gastric cancer patients using advanced mass spectrometry detection technology, in conjunction with both broad-spectrum and…
- Trial name
- NCT06109805
- Testing
- Gastric cancer
- Where
- 4 sites in China
- Volunteers
- 1,706 people, healthy volunteers welcome
- Sponsor
- Beijing Friendship Hospital
Bariatric Surgery, Hypertension
Effect of Bariatric Surgery on Cardiac Function in Patients With Hypertension
The purpose of this study is to investigate the effect of bariatric surgery on cardiac function assessed by echocardiography in patients with hypertension.
- Trial name
- NCT05166954
- Testing
- LSG, RYGB
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Beijing Friendship Hospital
Metabolic Dysfunction Associated Steatotic Liver Disease, Metabolic Dysfunction-associated Steatohepatitis (MASH)
Clinical Classification of MAFLD Based Liver Biopsy
Metabolic dysfunction-associated Fatty Liver Disease (MAFLD), also known as Non-Alcoholic Fatty Liver Disease (NAFLD), is the most common chronic progressive liver disease in China.
- Trial name
- NCT06795646
- Where
- 6 sites in China
- Volunteers
- 2,000 people
- Sponsor
- Beijing Friendship Hospital
CAEBV (Chronic Active Epstein-Barr Virus Infection) Syndrome, EBV
A Study on Efficacy and Safety of iNK Cells for CAEBV /EBV-HLH After Allo-HSCT
To evaluate the efficacy and safety of iNK cells infusion in patients with chronic active Epstein-Barr virus infection (CAEBV) and EBV-associated hemophagocytic lymphohistiocytosis (EBV-HLH) after allogeneic hematopoietic stem…
- Conditions
- CAEBV (Chronic Active Epstein-Barr Virus Infection) Syndrome, EBV, Hemophagocytic Lymphohistiocytoses
- Trial name
- NCT06491719
- Testing
- NCR300（Allogenic Ipsc-derived Natural Killer cells ）
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Beijing Friendship Hospital
Bariatric Surgery Candidate, NAFLD
Effectiveness of Bariatric Surgery for NAFLD/NASH
This is a prospective, multicenter cohort study, which subjects were obese patients requiring bariatric surgery. This study aims to explore the the effectiveness of bariatric surgery for NAFLD/NASH with fribrosis, to explore the…
- Conditions
- Bariatric Surgery Candidate, NAFLD, NASH With Fibrosis
- Trial name
- NCT04366999
- Testing
- SG, RYGB, OAGB
- Where
- China
- Volunteers
- 320 people
- Sponsor
- Beijing Friendship Hospital
Metabolic Surgery
Greater China Metabolic and Bariatric Surgery Database
Metabolic surgery, as a recognition treatment option for patients with clinical morbid obesity, is gaining increasing appreciation.
- Trial name
- NCT03800160
- Where
- China
- Volunteers
- 50,000 people
- Sponsor
- Beijing Friendship Hospital
Thyroid Function, Iodine Nutrition Status
Longitudinal Study on the Influence of Iodine Nutrition Status on Thyroid Function of Childbearing Age Women During Pregnancy and 6 Weeks Postpartum
The goal of this observational study is to provide a reference for formulating individual appropriate iodine intake programs for women during pregnancy and postpartum and improving the monitoring and evaluation system of maternal…
- Trial name
- NCT05677581
- Testing
- iodine nutrition status
- Where
- China
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- Beijing Friendship Hospital
Lung Cancer, Breast Cancer
Plasma Metabolic Biomarkers for Multi-Cancer Diagnosis
The aim of this observational study is to comprehensively analyze the metabolites in plasma samples from multi-cancer patients using advanced mass spectrometry detection technology, in conjunction with metabolomics approaches.
- Conditions
- Lung Cancer, Breast Cancer, Colorectal Cancer, Thyroid Cancer
- Trial name
- NCT06363123
- Where
- 4 sites in China
- Volunteers
- 2,700 people, healthy volunteers welcome
- Sponsor
- Beijing Friendship Hospital
HLH
Zanubrutinib for HLH
This study is a prospective single-arm clinical study, focusing on Hemophagocytic lymphohistocytosis，to evaluate the clinical efficacy and safety of zanubrutinib.
- Trial name
- NCT05320575
- Testing
- Zanubrutinib
- Where
- China
- Volunteers
- 16 people
- Sponsor
- Beijing Friendship Hospital
Gastric Cancer, Esophagus Cancer
Exosome-based Liquid Biopsies for Upper Gastrointestinal Cancers Diagnosis
This study constitutes a case-control investigation employing a retrospective approach. Plasma samples from individuals with esophageal cancer, benign esophageal diseases, gastric cancer, benign gastric diseases, and a healthy…
- Trial name
- NCT06278064
- Testing
- Gastric Cancer, Esophagus Cancer
- Where
- 3 sites in China
- Volunteers
- 562 people, healthy volunteers welcome
- Sponsor
- Beijing Friendship Hospital
HLH
Teniposide Incorporating Bu/Cy Conditioning Regimen for HLH With Central Nervous System Involvemen
Hemophagocytic lymphohistiocytosis (HLH) is a highly inflammatory disease involving cytokine storms and is characterised by rapid progression and high mortality.
- Trial name
- NCT06048107
- Testing
- Teniposide
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Beijing Friendship Hospital