Clinical trials: sponsored by Beth Israel Deaconess Medical Center
Artificial Intelligence (AI), Clinical Reasoning
Teaching Doctors in Training to Reason With Artificial Intelligence
The purpose of the TEACH-AI study is to assess whether a brief, structured workshop on artificial intelligence can improve the performance of medicine doctors in training (i.e.
- Conditions
- Artificial Intelligence (AI), Clinical Reasoning, Clinical Decision-making, Medical Education
- Trial name
- TEACH-AI (NCT07813754)
- Testing
- Workshop-First
- Where
- 4 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Parkinson's Disease
Gastrointestinal Dopamine Decarboxylase and Levodopa Pharmacokinetics
The main treatment for Parkinson's disease is a medication called levodopa. Levodopa has to be absorbed from the gut and travel to the brain to work, but a naturally occurring enzyme in the lining of the stomach, called dopamine…
- Trial name
- NCT07793461
- Testing
- Levodopa (L-dopa)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Beth Israel Deaconess Medical Center
Joint Replacement Surgery
Reversal of Spinal Anesthesia Residual Motor Block Via Intrathecal Catheter
The purpose of this study is to determine the feasibility of administering a predetermined amount of normal saline into the intrathecal or subarachnoid space via a small spinal catheter to reduce or eliminate the effects of…
- Trial name
- IT-Cath (NCT07404982)
- Testing
- Normal Saline 10 mL Injection
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Beth Israel Deaconess Medical Center
Meditation, Cognitive Reappraisal
Transforming Adolescent Perception and Mental Health Through Meditation and Cognitive Reappraisal A Mixed Method Study
This study will evaluate how a comprehensive meditation-based program, Inner Engineering, supports teens ages 15-18 in becoming more joyful, focused, resilient, and better equipped to manage stress and thrive.
- Conditions
- Meditation, Cognitive Reappraisal, Emotional Regulation
- Trial name
- THRIVE (NCT07173608)
- Testing
- Inner Engineering Program
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Focal Segmental Glomerulosclerosis, Nephrotic Syndrome
Genetic Causes of FSGS, Nephrotic Syndrome, or Kidney Failure
The investigators are trying to learn more about the cause of kidney diseases such as Focal Segmental Glomerulosclerosis (FSGS) and Nephrotic syndrome by studying genetics.
- Conditions
- Focal Segmental Glomerulosclerosis, Nephrotic Syndrome, End Stage Renal Disease, Kidney Failure
- Trial name
- FSGS (NCT02194582)
- Where
- United States
- Volunteers
- 2,050 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Crohn Disease, Ulcerative Colitis
Proactive Infliximab Optimization Using a Pharmacokinetic Dashboard Versus Standard of Care in Patients With Inflammatory Bowel Disease: The OPTIMIZE Trial
The OPTIMIZE Trial compares whether iDose dashboard-driven infliximab dosing (iDose-driven dosing) is more effective and safer than standard infliximab dosing for inducing and maintaining disease remission in inflammatory bowel…
- Conditions
- Crohn Disease, Ulcerative Colitis, Inflammatory Bowel Diseases
- Trial name
- NCT04835506
- Testing
- Infliximab
- Where
- 25 sites in United States, Canada
- Volunteers
- 124 people
- Sponsor
- Beth Israel Deaconess Medical Center
Clinical High Risk for Psychosis
Individualized Vocational and Educational Support and Training for Clinical High Risk for Psychosis (InVEST)
The purpose of this study is to test the efficacy of InVEST (Individualized Vocational and Educational Support and Training) for CHR-P (clinical high risk for psychosis) to address specific role functioning difficulties…
- Trial name
- InVEST (NCT05114733)
- Testing
- InVEST
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Beth Israel Deaconess Medical Center
Perinatal Depression, Perinatal Anxiety
Testing "Doula Link", a Multi-Component Intervention to Improve Perinatal Mental Health
Doulas are trained individuals who offer informational, emotional, and physical support to their pregnant, birthing, and postpartum clients.
- Trial name
- Doula Link (NCT07217561)
- Testing
- Doula Link
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Stenosis of Trachea
Spray Cryotherapy for the Management of Benign Central Airway Stenosis (Cryo-BAS)
The goal of this clinical trial is to compare spray cryotherapy plus balloon dilatation versus current standard of Care (SoC - steroid injection, radial cuts and balloon dilatation) in patients with benign airway stenosis with…
- Trial name
- Cryo-BAS (NCT06761170)
- Testing
- Spray cryo therapy, Standard of Care (SOC)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Beth Israel Deaconess Medical Center
Psychosis; Schizophrenia-Like, Healthy Controls
Mechanisms of Response to Therapeutic Intervention in Clinical High Risk (CHR) for Psychosis
This study, "Psychobiological Follow-up Study of Transition from Prodrome to Early Psychosis", will be conducted in collaboration with the Shanghai Mental Health Center (SMHC) and several data processing sites in the United…
- Trial name
- NCT06542640
- Testing
- Mb-rt-fMRI-NFB, rTMS
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Aortic Stenosis, Transcatheter Aortic Valve Replacement
Transcatheter Aortic Valve Replacement (TAVR) Effects on Cardiac Conduction System
This is a prospective observational study, the purpose of which is to: 1. Characterize response of the AV conduction system to TAVR with various prostheses by recording continuous His bundle electrograms during valve placement.
- Conditions
- Aortic Stenosis, Transcatheter Aortic Valve Replacement, Heart Block
- Trial name
- TAVR-HBE (NCT04982406)
- Testing
- Transcatheter aortic valve replacement
- Where
- United States
- Volunteers
- 409 people
- Sponsor
- Beth Israel Deaconess Medical Center
Burnout, Adverse Event
The Impact of a Novel Coaching Program on Medical Errors and Well-Being of Physicians
This is a randomized controlled trial with a mixed method design to determine the impact of coaching on self-perceived medical errors, burnout, and resilience.
- Conditions
- Burnout, Adverse Event, Medical Education
- Trial name
- CARE (NCT05557981)
- Testing
- Coaching
- Where
- United States
- Volunteers
- 332 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Small Fiber Neuropathy, Idiopathic Peripheral Neuropathy
IVIg for Small Fiber Neuropathy With Autoantibodies TS-HDS and FGFR3
The objective of this study is to develop a rationale for the selective treatment of small fiber neuropathy with immune globulin (IVIG) in the appropriate patients.
- Trial name
- NCT03401073
- Testing
- Intravenous immunoglobulin, 0.9% Sodium Chloride
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Beth Israel Deaconess Medical Center
Post-operative Recovery for Cesarean Hysterectomy Patients
Enhanced Recovery After Cesarean Hysterectomy
The enhanced recovery after surgery (ERAS) pathway is a well-described evidence-based protocol to optimize patient post-operative recovery. Patients undergoing cesarean hysterectomies are a unique surgical population.
- Trial name
- NCT04205149
- Testing
- ERAS post-operative pathway
- Where
- United States
- Sponsor
- Beth Israel Deaconess Medical Center
Functional Gastrointestinal Disorders
Managing Side Effects in Clinical Practice
This is a quality improvement health services study in the Division of Gastroenterology at Beth Israel Deaconess Medical Center (BIDMC).
- Trial name
- NCT03475550
- Testing
- Standard of Care
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Beth Israel Deaconess Medical Center
Healthy
Identification of L3-L4 Interspace in Parturients
The investigators hypothesize that teaching ultrasound sonoanatomy to identify the L3-L4 interspace will improve resident's long term skill to correctly identify the interspace as compared to palpation alone.
- Trial name
- NCT02697747
- Testing
- Education
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Beth Israel Deaconess Medical Center
Celiac Disease
Serum Markers in Gluten Challenge
1. The purpose of this research study is to evaluate non-invasive markers of celiac disease activity in subjects that are on a gluten-free diet, in remission from celiac disease who undergo gluten challenge. 2.
- Trial name
- NCT00931892
- Testing
- Gluten
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Beth Israel Deaconess Medical Center
Improving Team Work at the Planned Parenthood Affiliates
Stepping Up for Safety: Improving Teamwork at the Planned Parenthood Affiliates Through the TeamSTEPPS Model
TeamSTEPPS (Team Strategies and Tools to Enhance Performance and Patient Safety) is an evidence-based teamwork system designed to improve communication and teamwork skills among health professionals.
- Trial name
- NCT02260245
- Testing
- Team training using the TeamSTEPPS model
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Autism
Testing a Novel Speech Intervention in Minimally Verbal Children With Autism Spectrum Disorder (ASD)
The goal of the Novel Language Intervention for minimally verbal children with Autism Spectrum Disorder (ASD) is to test the efficacy of one experimental treatment (AMMT) compared to baseline assessments and compare the AMMT…
- Trial name
- NCT03015272
- Testing
- Auditory-Motor Mapping Training, Speech-Repetition Therapy
- Where
- 2 sites in United States
- Volunteers
- 14 people
- Sponsor
- Beth Israel Deaconess Medical Center
Acute Respiratory Distress Syndrome
EPVent 2- A Phase II Study of Mechanical Ventilation Directed by Transpulmonary Pressures
This phase II multi-centered, randomized controlled trial of mechanical ventilation directed by esophageal pressure measurement will test the primary hypothesis that using a strategy of maintaining a minimal but positive…
- Trial name
- EPVent2 (NCT01681225)
- Testing
- Esophageal-pressure guided mechanical ventilation, High PEEP mechanical ventilation
- Where
- 14 sites in United States, Canada
- Volunteers
- 202 people
- Sponsor
- Beth Israel Deaconess Medical Center