Clinical trials: sponsored by British Columbia Cancer Agency
B-Cell Leukemia, Non-Hodgkin's Lymphoma
CLIC-2201 for the Treatment of Relapsed/Refractory B Cell Malignancies
This is a phase I dose-finding trial of an autologous CD22 targeting chimeric antigen receptor (CAR)-T cell product, called CLIC-2201, for participants with relapsed/refractory B cell malignancies.
- Conditions
- B-Cell Leukemia, Non-Hodgkin's Lymphoma, B-cell Acute Lymphoblastic Leukemia, Diffuse Large B Cell Lymphoma
- Trial name
- NCT06208735
- Testing
- CLIC-2201
- Where
- 7 sites in Canada
- Volunteers
- 24 people
- Sponsor
- British Columbia Cancer Agency
Thyroid Cancer, Medullary, Carcinoid Tumor
18F-FDOPA PET in Neuroendocrine Tumours
Neuroendocrine tumours (NETs) are a group of neoplasms generally arising from the gastroenteropancreatic tract. They are usually slow growing, have low malignant potential, and often go unnoticed until they become metastatic.
- Conditions
- Thyroid Cancer, Medullary, Carcinoid Tumor, Pheochromocytoma, Paraganglioma
- Trial name
- NCT02431715
- Testing
- [18 F]-6-L-fluorodihydroxyphenylalanine (18F-FDOPA)
- Where
- Canada
- Sponsor
- British Columbia Cancer Agency
Head and Neck Cancer
PATH Trial: Personalized Approaches in the Treatment of Head and Neck Cancer
1. To determine genomic markers of radioresistance by comparing patients with H\&N cancer who develop recurrence within twelve months of curative intent radiation and/or chemoradiotherapy to those without recurrence 2.
- Trial name
- PATH (NCT05373251)
- Testing
- Whole genomic DNA/RNA tumour sequencing
- Volunteers
- 500 people
- Sponsor
- British Columbia Cancer Agency
Prostate Cancer
Living Well on Androgen Deprivation Therapy
Approximately half of men treated for prostate cancer will be offered hormone deprivation therapy during their cancer experience.
- Trial name
- NCT02108613
- Testing
- Exercise Sessions, Nutrition Education, Peer Support Volunteer
- Where
- Canada
- Sponsor
- British Columbia Cancer Agency
Radiotherapy Induced Mucositis, Head and Neck Cancer
A Randomized Placebo-Controlled Trial of Manuka Honey for Oral Mucositis Due to Radiation Therapy for Cancer
The primary hypothesis of this study is that regular topical oral application of Manuka Honey will reduce the severity and duration of oral mucositis in patients who are undergoing mucotoxic radiation therapy for cancer treatment.
- Trial name
- NCT00615420
- Testing
- manuka honey
- Where
- 2 sites in Canada
- Volunteers
- 106 people
- Sponsor
- British Columbia Cancer Agency
Constipation
The Bowel Research Collaborative Data Tracking System Implementation Study
The project's primary purpose is to establish a network of Hospice Palliative Care settings using a common and consistent method of assessing and documenting bowel functioning in order to be able to carry out future collaborative…
- Trial name
- NCT00728975
- Where
- Canada
- Volunteers
- 533 people
- Sponsor
- British Columbia Cancer Agency
Prostate Cancer
Intensity Modulated Versus Interstitial - Radiation Therapy
Purpose: The purpose of this trial is to compare two different treatment options for patients with low risk and low-tier intermediate risk prostate cancer.
- Trial name
- NCT00407875
- Testing
- Intensity Modulated External Beam Radiation Therapy
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- British Columbia Cancer Agency
Prostate Cancer
Intraprostatic MAXimal Simultaneous Boost
This trial uses a type of radiotherapy called intensity modulated radiotherapy (IMRT), which is able to deliver the radiation to the prostate while delivering less dose to the surrounding normal organs compared with standard 3D…
- Trial name
- NCT00798837
- Testing
- Intraprostatic maximal simultaneous boost
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- British Columbia Cancer Agency
Breast Cancer
Do Skin Markings Reflect the Location of the Surgical Cavity During Daily Radiotherapy Treatment?
Markings placed on the skin are an accurate representation of the underlying surgical cavity and are adequate to use for patient setup for accelerated partial breast irradiation.
- Trial name
- NCT00578747
- Where
- 2 sites in Canada
- Volunteers
- 21 people
- Sponsor
- British Columbia Cancer Agency
Gastrointestinal Neoplasms, Urogenital Neoplasms
Acupuncture for the Immune System in Radiation Cancer Patients
Purpose/Goal: To investigate how long course radiation therapy (RT), both with or without chemotherapy, affects the immune system, and to determine if acupuncture can modify these effects in patients undergoing curative radiation…
- Trial name
- NCT01422928
- Testing
- Medical Acupuncture
- Where
- Canada
- Sponsor
- British Columbia Cancer Agency
Head and Neck Carcinoma
Feasibility of VMAT and CBCT for Head and Neck Carcinomas
This will be a prospective longitudinal study describing clinical throughput metrics and patient reported quality of life outcome measures for patients undergoing Volumetric modulated arc therapy (VMAT) with and without Cone-beam…
- Trial name
- NCT01384890
- Testing
- VMAT with CBCT, VMAT with kV-ray
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- British Columbia Cancer Agency
Breast Cancer
Evaluation of the Informational Content of Setup Verification Images for Patients Receiving Breast Radiation Therapy (Anterior EPI)
The purpose of this study is to determine if an alternative imaging protocol done at the time of radiotherapy treatments for patients with breast cancer can improve accuracy in patient set-up.
- Trial name
- Anterior EPI (NCT00800189)
- Testing
- Anterior electronic portal images (EPI)
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- British Columbia Cancer Agency
Breast Cancer
Pilot Study of Partial Breast Irradiation Utilizing Permanent Breast Seed Implant to Treat Breast Cancer
Background: Recent single arm studies have suggested that partial breast irradiation (PBI), delivered in a relatively short overall treatment time of a few days, may be an effective alternative to adjuvant whole breast…
- Trial name
- NCT01191164
- Testing
- Partial Breast Irradiation Utilizing Permanent Breast Seed Implant
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- British Columbia Cancer Agency
Breast Neoplasms
The Use of Silver Leaf Dressing in the Prevention of Radiotherapy Induced Skin Reactions
The hypothesis is that silver leaf nylon dressing reduces the percentage of patients developing brisk erythema and moist desquamation while undergoing whole breast radiotherapy.
- Trial name
- NCT00207324
- Testing
- Silver Leaf Dressing
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- British Columbia Cancer Agency