Clinical trials: sponsored by Columbia University
Infantile Hemangioma
Optical Tomographic Imaging of Infantile Hemangiomas
The investigators hypothesize that there are differences between infantile hemangiomas (IH) during the proliferating and involuting phases and in response to medical treatment that can be detected by optical tomography of these…
- Trial name
- NCT01673971
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Columbia University
Twin Twin Transfusion Syndrome
Renal Artery Dopplers in Twin Twin Transfusion Syndrome
Twin-twin transfusion syndrome (TTTS) is a complication affecting 10-15% of monochorionic, diamniotic (MCDA) twin pregnancies. Unevenly distributed blood flow across a shared placental circulation results in a volume-restricted…
- Trial name
- NCT03449823
- Testing
- Doppler ultrasound of fetal renal artery
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Columbia University
Sinus Bradycardia, Atrioventricular Block
Analysis of Adenosine on Sinus and Atrioventricular Nodal Conduction in the Pediatric Transplanted Heart
Heart transplants save the lives of nearly 500 children in heart failure per year. Columbia is one of the largest pediatric heart transplant centers in the world, averaging 25 transplants per year, and providing ongoing care to…
- Trial name
- NCT02462941
- Testing
- Adenosine, Cardiac catheterization
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Columbia University
Sexual Assault, Interpersonal Relations
Creating Opportunities Through Mentoring, Parental Involvement and Safe Spaces - Ethiopia
The study is a randomized controlled trial of COMPASS, an intervention for adolescent girls in three refugee camps in Ethiopia. The study design will employ a two group wait-list cluster randomized controlled trial where girls…
- Conditions
- Sexual Assault, Interpersonal Relations, Marital Status, Domestic Violence
- Trial name
- COMPASS (NCT02506543)
- Testing
- COMPASS, No intervention
- Where
- 2 sites in United States, Ethiopia
- Volunteers
- 1,014 people
- Sponsor
- Columbia University
Sexual Assault, Interpersonal Relations
Creating Opportunities Through Mentoring, Parenting and Safe Spaces - Democratic Republic of Congo
The study is a randomized controlled trial of COMPASS, an intervention for adolescent girls in Eastern Democratic Republic of Congo.
- Conditions
- Sexual Assault, Interpersonal Relations, Marital Status, Domestic Violence
- Trial name
- COMPASS (NCT02384642)
- Testing
- COMPASS, COMPASS plus parenting
- Where
- United States
- Volunteers
- 1,633 people, healthy volunteers welcome
- Sponsor
- Columbia University
HIV (Human Immunodeficiency Virus)
Safe Generations Plus: Swaziland PMTCT LTF Study
This study is to understand how to improve retention in care and treatment services to HIV positive pregnant women and their babies in Swaziland.
- Trial name
- SG+ (NCT02969161)
- Where
- 10 sites in Eswatini
- Volunteers
- 616 people
- Sponsor
- Columbia University
Atopic Dermatitis
Texting Atopic Dermatitis Patients to Optimize Learning and EASI Scores
The purpose of this study is to determine if sending text messages with treatment reminders and facts regarding atopic dermatitis (AD) to caretakers of children with AD will have a positive effect on the disease severity.
- Trial name
- TADPOLES (NCT02779426)
- Testing
- Text messages
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Columbia University
Vaccination, Influenza
Influenza Vaccine Attitudes, Intent, and Receipt: Pediatric
Influenza vaccine is recommended as routine care for all individuals who are at least 6 months of age and older. Recently, questions about vaccine safety and concerns for side effects have increased, contributing to both…
- Trial name
- NCT02907580
- Testing
- Local educational information, National educational information
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Columbia University
Resting Energy Expenditure
Metabolic Effects of Differential Organ Growth Rates
Young children have a high resting energy expenditure (REE) relative to their body weight and metabolically active compartment, fat-free mass (FFM).
- Trial name
- NCT03219229
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Columbia University
Congenital Heart Disease
Prenatal Effects of Congenital Heart Disease (CHD) on Neurodevelopmental Outcome
The purpose of this study is to investigate the prenatal impact of abnormal cardiac structure on neurodevelopmental outcomes in children with congenital heart disease.
- Trial name
- NCT00713635
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Columbia University
Substance Use
Drug Abuse Prevention Among Girls Through a Mother-Daughter Intervention
The purpose of this study is to determine a computer- and family-based drug abuse prevention program is able to reduce drug use among early adolescent girls.
- Trial name
- NCT01236248
- Testing
- Prevention
- Where
- United States
- Volunteers
- 916 people, healthy volunteers welcome
- Sponsor
- Columbia University
Very Low Birth Weight Baby, Pneumonia
Intervening to Improve Infant Health in Ghana
The purpose of the study is to understand how cooking might affect the health of pregnant women and their babies. The goal of the research is to determine whether, interventions in decreasing exposure to smoke from cook stoves…
- Trial name
- NCT01335490
- Testing
- Cook stoves, either Biolite wood stove, or liquified petroleum gas stove plus fuel
- Where
- 2 sites in United States, Ghana
- Volunteers
- 1,414 people, healthy volunteers welcome
- Sponsor
- Columbia University
Hematopoietic Organs; Disorder
Probiotic Use in Children Undergoing Hematopoietic Stem Cell Transplantation (HSCT)
Primary Objective: 1. To evaluate the safety of orally administered Lactobacillus plantarum strains 299 and 299v, a probiotic, in patients undergoing allogeneic myeloablative HSCT, as measured by incidence of Lactobacillus…
- Trial name
- NCT01010867
- Testing
- Lactobacillus plantarum strains 299 and 299v
- Where
- 3 sites in United States
- Volunteers
- 31 people
- Sponsor
- Columbia University
Viral Hepatitis B, Contraception
Blood-borne Infection Screening in an Afghan Antenatal Population
Baseline information indicates there are measurable levels of hepatitis B SAg and low utilization of postpartum contraception, correct breastfeeding practices, or adherence to infant vaccination schedules in Kabul, Afghanistan.
- Conditions
- Viral Hepatitis B, Contraception, Breast Feeding, Exclusive, Effects of; Lack of Care of Infants
- Trial name
- NCT01199601
- Testing
- Concentrated postpartum counseling
- Where
- Afghanistan
- Volunteers
- 1,291 people, healthy volunteers welcome
- Sponsor
- Columbia University
Cerebral Palsy
Intensive Home-based Bimanual and Lower-limb Training in Young Children With Hemiplegia
A randomized control trial to test the efficacy of a new treatment involving intensive home-based bimanual training (Hand-Arm Bimanual Intensive Therapy (HABIT) and intensive home-based functional lower-limb training in children…
- Trial name
- NCT02299284
- Testing
- Intensive Home-based Bimanual and Lower-limb Training in Young Children With Hemiplegia
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Teachers College, Columbia University
Child Survival
Millennium Villages Project in Sub-Saharan Africa
The Millennium Villages Project involves the coordinated and simultaneous delivery of a package of proven interventions in health, agriculture, infrastructure and education.
- Trial name
- MVP (NCT01125618)
- Testing
- Health and development intervention package, Routine services
- Where
- 11 sites in Ethiopia, Ghana and 8 more
- Volunteers
- 65,000 people, healthy volunteers welcome
- Sponsor
- Columbia University
Infants in Neonatal Intensive Care Units
Improving Antimicrobial Prescribing Practices in the Neonatal ICU
To determine if 3 randomly assigned bundles of stewardship interventions would reduce overall and inappropriate antimicrobial use in the neonatal intensive care unit (NICU), a pre-post study was performed in 4 NICUs.
- Trial name
- iNAP (NCT03079245)
- Testing
- Education Plus (E+), Clinical Decision Support, Prescriber Audit and Feedback
- Where
- 4 sites in United States
- Volunteers
- 6,184 people
- Sponsor
- Columbia University
HIV/AIDS, HIV Infections
Treatment Options for Protease Inhibitor-exposed Children
The investigators hypothesize that switching to a regimen based on efavirenz will be as effective and safe as remaining on a regimen based on Lopinavir/ritonavir for HIV-infected children.
- Trial name
- NEVEREST-III (NCT01146873)
- Testing
- Efavirenz (EFV), Lopinavir/ritonavir (LPV/r), Stavudine (D4T)
- Where
- South Africa
- Volunteers
- 300 people
- Sponsor
- Columbia University
HIV/AIDS
Pediatric Decentralization of ART in South Africa
The decentralization study will describe children taking antiretroviral therapy (ART) at a larger health facility in the Eastern Cape province of South Africa, between the years of 2004-2013.
- Trial name
- NCT03049891
- Testing
- Data abstraction, Tracing questionnaire, Tier.net
- Where
- 15 sites in South Africa
- Volunteers
- 1,583 people
- Sponsor
- Columbia University
Pneumonia, Acute Respiratory Infection
CPAP Survival Study in Ghana
The purpose of this study is to determine if the use of a continuous positive airway pressure (CPAP) machine (a device that blows air into the lungs) decreases the chance of a child dying from difficulty breathing.
- Trial name
- NCT01839474
- Testing
- CPAP
- Where
- 2 sites in Ghana
- Volunteers
- 2,200 people
- Sponsor
- Columbia University