Clinical trials: sponsored by Lund University
Depressive Disorder, Major
Aerobic Versus Leisure Group for Adolescents With Depression
The aim is to evaluate aerobic group exercise versus leisure group activities in adolescents with mild to moderate depression. Primary outcome is Children's Depression Rating Scale - Revised (CDRS-R).
- Trial name
- NCT05076214
- Testing
- Aerobic exercise in group, Leisure activities in group
- Where
- 4 sites in Sweden
- Volunteers
- 125 people
- Sponsor
- Lund University Hospital
HIV-related Stigma, Psychological Wellbeing
Digital Peer-support-based Anti-HIV Stigma Intervention Among Adolescents Living With HIV in Ethiopia
Advances in HIV care and treatment turned a once deadly disease into a chronic condition where people living with HIV, including perinatally HIV acquired children, can now lead a healthy life and live longer with their highly…
- Conditions
- HIV-related Stigma, Psychological Wellbeing, Retention in Care
- Trial name
- NCT07425925
- Testing
- Peer support based digital anti-HIV stigma intervention, A standard in-clinic in-person psychosocial support
- Where
- 5 sites in Ethiopia
- Volunteers
- 239 people
- Sponsor
- Lund University
Absenteeism, School Absenteeism
Early Absenteeism Guide for Lifelong Education
School absenteeism is a problem that can be caused by several different factors, such as difficulties within the family, problems in the school environment, or mental health difficulties.
- Trial name
- EAGLE (NCT07857603)
- Testing
- Intervention , EAGLE, Treatment as usual (TAU)
- Volunteers
- 90 people
- Sponsor
- Lund University
Sport-related Concussion
Effect of Neck Training on Outcomes Related to Sport-Related Concussion
Sport-related concussion (SRC) is a significant concern in soccer. This pilot quasi-experimental trial aims to investigate the efficacy and acceptability of an evidence-based neck resistance exercise program in female soccer…
- Trial name
- NCT06774976
- Testing
- 8-week Evidence-Based Neck Resistance Training Program
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Lund University
Celiac Disease in Children
Prevention of Celiac Disease in Skåne
This study aims to investigate the impact of being on a gluten free diet the first three years of life compared to a daily intake of a probiotic supplementation or placebo on the risk of developing celiac disease autoimmunity or…
- Trial name
- PreCiSe (NCT03562221)
- Testing
- Gluten free diet, Probiotics
- Where
- Sweden
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Lund University
Type 1 Diabetes Mellitus, Stage 2 Type 1 Diabetes
Information, Follow-up and Early Diagnosis of Children at Risk for Type 1 Diabetes
The aim is to investigate whether screening for islet autoantibodies, regular follow-up, and increased knowledge in families about the progression of the disease in children at high genetic risk or with single or multiple islet…
- Conditions
- Type 1 Diabetes Mellitus, Stage 2 Type 1 Diabetes, Stage 1 Type 1 Diabetes, Stage 3 Type 1 Diabetes
- Trial name
- iT1D (NCT06676566)
- Where
- Sweden
- Volunteers
- 600 people
- Sponsor
- Lund University
HIV-1-infection, Antiretroviral Therapy
HIV Transmission in the Era of Scaling up Antiretroviral Therapy in Ethiopia
The goal of this observational study is to understand patterns of HIV transmission in a high-prevalence area in Ethiopia, and to compare viral genetic information in people with HIV who are newly diagnosed and have not been…
- Trial name
- THESA (NCT05652400)
- Testing
- Exposure to antiretroviral therapy
- Where
- Ethiopia
- Volunteers
- 2,200 people
- Sponsor
- Lund University
Heart Rate Determination, Patient Participation
Promoting Children's Participation in Conventional X-ray Examinations
The goal of this explorative observational study is to map the procedure and child centered approach in the examination for children that undergo conventional X-ray examinations.
- Trial name
- NCT06322264
- Testing
- Measurement of variation in heart rate
- Where
- Sweden
- Volunteers
- 220 people
- Sponsor
- Lund University
Anxiety, Depression
Mindfulness as a Method of Improving the Well-being, Quality of Life and Health of Primary School Pupils
This study evaluates the short and long-term effect of 5-10 minutes daily mindfulness and compassion training in school among children aged between 6-16 years old.
- Trial name
- NCT03327714
- Testing
- Mindfulness and compassion
- Where
- Sweden
- Volunteers
- 1,750 people, healthy volunteers welcome
- Sponsor
- Lund University
Breast Neoplasms
Sweden Cancerome Analysis Network - Breast : Genomic Profiling of Breast Cancer
This study evaluates the genomic profiles of breast cancer in a prospective and population-based manner. In the first phase, breast tumors are analyzed by whole transcriptome RNA-sequencing.
- Trial name
- SCAN-B (NCT02306096)
- Where
- 10 sites in Sweden
- Volunteers
- 20,000 people
- Sponsor
- Lund University
Hand Osteoarthritis
Outcomes After First-line Treatment of Hand Osteoarthritis
This study will investigate outcomes of a 3-month first-line treatment program for hand osteoarthritis, using data from the Swedish Osteoarthritis Registry.
- Trial name
- NCT07708454
- Testing
- 3 months of exercise and education
- Volunteers
- 2,000 people
- Sponsor
- Lund University
Heart Disease Congenital, Ventricular Septal Defect
Improving Care for Children With Congenital Heart Disease.
Establish a cardiovascular biomarker profile to help screening for congenital heart disease in infants and children as well as use non-invasive cardiac imaging in combination with such profiling to better predict the need for…
- Conditions
- Heart Disease Congenital, Ventricular Septal Defect, Atrial Septal Defect, Patent Ductus Arteriosus
- Trial name
- NCT04667455
- Testing
- Biomarker analysis at enrolment, Biomarker analyses throughout the study
- Where
- Sweden
- Volunteers
- 313 people, healthy volunteers welcome
- Sponsor
- Lund University Hospital
Athletic Injuries, Health Behavior
Implementing Injury Prevention Training in Youth Handball (I-PROTECT) Using the RE-AIM Evaluation Framework
The aim of this two-armed cluster-randomized controlled trial is to investigate the implementation of the I-PROTECT using the RE-AIM evaluation framework that addresses five dimensions of effectiveness and implementation of…
- Trial name
- I-PROTECT (NCT05696119)
- Testing
- I-PROTECT, Control
- Where
- Sweden
- Volunteers
- 4,225 people, healthy volunteers welcome
- Sponsor
- Lund University
Celiac Disease in Children, Autoimmune Diseases
Gluten Reduction and Risk of Celiac Disease
Celiac disease shares many features of other autoimmune diseases such as type 1 diabetes. Recently, it was published that higher amounts of gluten intake increased the risk for celiac disease.
- Conditions
- Celiac Disease in Children, Autoimmune Diseases, type1diabetes
- Trial name
- GRAIN (NCT04593888)
- Testing
- Gluten reduced diet
- Where
- Sweden
- Volunteers
- 1,141 people
- Sponsor
- Lund University
Type 1 Diabetes, Autoimmune Diabetes
Intensive Dietary and Activity Counselling (IDAC)
The aim of this intervention study is to investigate if a intensive dietary and physical activity counselling during the first two years of life in children with increased (genetically) risk for Type 1 Diabetes (T1D) can promote…
- Trial name
- IDAC (NCT06670625)
- Testing
- IDAC+
- Where
- Sweden
- Volunteers
- 1,244 people
- Sponsor
- Lund University
Celiac Disease in Children, Type 1 Diabetes
Prevention av Autoimmunitet Med Laktobaciller
The incidence of autoimmune diseases (celiac disease, type 1 diabetes, thyroid disease) have increased over the past 30 years. Although most autoimmune diseases have a strong link to different risk genes, the rapid increase is…
- Conditions
- Celiac Disease in Children, Type 1 Diabetes, Thyroid
- Trial name
- PAL (NCT04014660)
- Testing
- Probiotic
- Where
- Sweden
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Lund University
Preterm Birth, Pediatric Cancer
eHealth as an Aid for Facilitating and Supporting Self-management in Families With Long-term Childhood Illness
The overall aim is twofold: 1) to stretch the borderline regarding the present knowledge of clinical and economic cost-effectiveness of eHealth as an aid for facilitating and supporting self-management in families with long-term…
- Conditions
- Preterm Birth, Pediatric Cancer, Hirschsprung Disease, Congenital Malformation
- Trial name
- eChildHealth (NCT04150120)
- Testing
- e-health device with application, Mobile phone text messaging, early detection of cerebral palsy using a mobile phone application
- Where
- 7 sites in Denmark, Ethiopia and 1 more
- Volunteers
- 720 people
- Sponsor
- Lund University
ANXIETY DISORDERS (or Anxiety and Phobic Neuroses), Specific Phobia
Internet-Delivered Cognitive Behavioral Intervention for Youths With Anxiety Disorders
The goal of this study is to develop a new internet-delivered cognitive behavioral therapy (ICBT) intervention for youths with anxiety disorders based on the best current knowledge about effective cognitive behavioral therapy for…
- Conditions
- ANXIETY DISORDERS (or Anxiety and Phobic Neuroses), Specific Phobia, Social Anxiety Disorder, Separation Anxiety Disorder
- Trial name
- NCT06661460
- Testing
- Internet-Delivered Cognitive Behavioral Therapy
- Where
- Sweden
- Volunteers
- 48 people
- Sponsor
- Lund University
Temporomandibular Disorders (TMD), Temporomandibular Joint Ankylosis
Virtual Planning of Total Temporomandibular Joint Replacement
A total TMJ replacement surgery is currently planned based on the X-ray appearance of the facial X-ray. It is now possible to use either an individually designed TMJ prosthesis or a prosthesis with a standard appearance.
- Trial name
- NCT07373184
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Lund University Hospital
Children With Cerebral Palsy Who Are Ambulant, Cerebral Palsy GMFCS-ER I-II
Exercise Training Among Children With Cerebral Palsy to Increase Health and Well-being - A Feasibility Study
The use of eHealth in children with cerebral palsy (CP) holds promise to increase participation in exercise. eHealth, has shown to increase accessibility to appropriate healthcare professionals as well as reduces time- and energy…
- Trial name
- HOME-EX (NCT07025694)
- Testing
- A eHealth application on a computer tablet contected to a secure severer with an interface on a computer to deliver exercise interventions., A eHealth application on a computer tablet contected to a secure severer with an interface on a computer to deliver exercise interventions, Moderate Intensity Continues Training
- Where
- Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lund University