Clinical trials: sponsored by Unity Health Toronto
Critically Ill
Frequency of Screening and SBT Technique Trial
The requirement for invasive mechanical ventilation is a defining feature of critical illness. Liberation or weaning is the process during which the work of breathing is transferred from the ventilator back to the patient.
- Trial name
- FAST (NCT02399267)
- Testing
- Once daily screening, Twice daily screening, PS SBTs
- Where
- 10 sites in United States, Canada
- Volunteers
- 100 people
- Sponsor
- Unity Health Toronto
Hysterectomy for Abnormal Uterine Bleeding
Laparoscopic Gynecology Curriculum for Residents
Gynecologists are currently using laparoscopy to perform many surgeries traditionally approached by laparotomy. The technical skills required for laparoscopic surgery are different than the skills required for laparotomy, causing…
- Trial name
- NCT01916343
- Testing
- Study Laparoscopic Curriculum
- Where
- Canada
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
HIV, AIDS Virus
HIV Testing in Pregnant Women: Evaluating an Opt-Out Testing Strategy
Mother-to-child transmission of HIV is an important but preventable mode of infection. Prevention depends on identifying pregnant women infected with HIV and offering medications during pregnancy which can dramatically decrease…
- Conditions
- HIV, AIDS Virus, Pregnancy
- Trial name
- NCT00393302
- Testing
- HIV screening in pregnancy
- Where
- Canada
- Volunteers
- 1,074 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Human Immunodeficiency Virus, HIV
Fetal HIV Transmission Risk and Duration of Membrane Rupture
In optimally managed HIV+ women with undetectable viral loads, who are on HAART and also receiving intrapartum IV ZDV, the risk of vertical transmission of HIV is independent of the length of time of rupture of membranes.
- Trial name
- NCT01616823
- Where
- Canada
- Volunteers
- 210 people
- Sponsor
- Unity Health Toronto
HPV
Human Papilloma Virus (HPV) Knowledge and Attitudes and the Role of (SES) Socioeconomic Status and Ethnicity
This is a survey study to assess the vaccination knowledge and attitudes of women in an inner city Gynecology clinic. Results of this study will help determine which factors influence vaccination knowledge and attitudes.
- Trial name
- NCT01105000
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Hepatitis C, Pregnancy
Screening for Hepatitis C During Pregnancy at a Toronto Inner City Prenatal Clinic
The first part of this study will investigate the incidence of Hepatitis C in pregnant women attending an inner city health clinic in downtown Toronto.
- Trial name
- NCT00348660
- Where
- Canada
- Volunteers
- 653 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Rubella, Vaccine
Rubella Susceptibility in Multiparous Women
The purpose of this study is to determine the reasons why multiparous women (women who are pregnant and have been pregnant before) might still be susceptible to rubella.
- Trial name
- NCT00401505
- Where
- Canada
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
HIV
HIV Physician's Survey
This is a survey study to assess the variability in the current management of pregnancy, reproductive care and assisted reproductive technologies for HIV-positive individuals in Canada to estimate interest for further projects.
- Trial name
- NCT01104974
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Evaluation of Laparoscopic Hysterectomy Simulator
Evaluation of Laparoscopic Hysterectomy Simulator
This study aims to test the validity of a new educational tool in the form of a computer based video surgical simulator, that may be used to enhance the current teaching method of how to perform a hysterectomy.
- Trial name
- NCT02234856
- Testing
- Laparoscopic Hysterectomy trainer
- Where
- 6 sites in United States, Canada and 1 more
- Volunteers
- 45 people
- Sponsor
- Unity Health Toronto
Influenza, Vaccine
Influenza Vaccine Postpartum Questionnaire
The purpose of this trial is to assess the knowledge and attitudes of post-partum women regarding influenza and the use of the influenza vaccine in pregnancy.
- Conditions
- Influenza, Vaccine, Pregnancy
- Trial name
- NCT00401700
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Influenza, Pregnancy
Influenza Vaccine in Pregnancy Part 2
Pregnant women have limited knowledge regarding influenza, its implications during pregnancy, and recommendations for vaccination during pregnancy.
- Trial name
- NCT00593970
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Postpartum Depression
Postpartum Anemia and Postpartum Depression
Postpartum anemia (PPA) and Postpartum depression (PPD) are common afflictions affecting women after childbirth. Both disorders have a significant impact on women's health and functional status.
- Trial name
- PPADS (NCT00782912)
- Where
- Canada
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Gonococcal Infection, Chlamydia Infections
Screening of Gonococcal and Chlamydial Infections in the Third Trimester
Untreated maternal infection with gonorrhea and/or chlamydia can have serious complications in pregnancy and the neonatal period.
- Trial name
- NCT03073538
- Volunteers
- 1,691 people
- Sponsor
- Unity Health Toronto
Surgical Videos, Pre-operative Training
Effect of Pre-operative Training Using Surgical Videos on Resident Performance of Unilateral Salpigo-oophrectomy
There is a need for the development and validation of new teaching strategies and resources for surgical training that can occur outside of the operating room.
- Trial name
- NCT03230552
- Testing
- Instructional surgical video
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Post-Traumatic Stress Disorder
Lending a Hand to Our Future: PTSD in Refugee Children and Youth
Immigrant and refugee children and youth are the fastest growing segment of Canadian society, but their mental health is too often overlooked even though their high rates of symptoms are increasingly of concern.
- Trial name
- LHOF (NCT02334566)
- Testing
- NET TX
- Volunteers
- 588 people
- Sponsor
- Unity Health Toronto
Mitral Valve Prolapse
The Canadian Mitral Research Alliance (CAMRA) Trial CardioLink-2
Multicentre, double-armed, randomized controlled trial designed to compare mitral valve leaflet resection versus leaflet preservation with regards to the development of functional mitral stenosis following surgical repair of…
- Trial name
- CAMRA (NCT02552771)
- Testing
- Mitral repair with leaflet preservation, Mitral repair with leaflet resection
- Where
- 6 sites in Canada
- Volunteers
- 104 people
- Sponsor
- Unity Health Toronto
Critically Ill
The Frequency of Screening and SBT Technique Trial: The FAST Trial
Background: The sickest patients who are admitted to an intensive care unit (ICU) often require assistance with their breathing.
- Trial name
- NCT02969226
- Testing
- Once daily screening, Twice daily screening, PS SBTs
- Where
- 17 sites in United States, Canada
- Volunteers
- 760 people
- Sponsor
- Unity Health Toronto
Syphilis
Evaluation of Enhanced Syphilis Screening Among HIV-positive Men
This study aims to enhance syphilis testing among HIV-positive men who have sex with men (MSM), so that more men will undergo testing, they will test more often, and more cases will be treated early.
- Trial name
- NCT02019043
- Testing
- Syphilis testing with routine HIV bloodwork
- Where
- 4 sites in Canada
- Volunteers
- 3,895 people
- Sponsor
- Unity Health Toronto
Traumatic Brain Injury With Prolonged Loss of Consciousness
A Trial to Determine the Feasibility and Effectiveness of Early Multisensory Stimulation Intervention in Patients in the Trauma-Neurosurgical Intensive Care Unit (TNICU) Following Severe Acquired Brain Injury
St. Michael's Hospital (SMH) provides service to individuals with some of the most severe brain injuries and intensive care needs in Canada.
- Trial name
- NCT02589223
- Testing
- Multisensory Stimulation, Control
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- Unity Health Toronto
Diabetes
Investigating Ultrasound Debridement in Wound Care
The initial step of wound management, debridement, is thought to be critical in promoting wound healing. Of the numerous debridement modalities, ultrasound seems to hold promising results in accelerate healing in our own clinical…
- Trial name
- NCT03516422
- Testing
- ULTRASOUND DEBRIDEMENT, STANDARD CARE GROUP
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto