Clinical trials: sponsored by University of Chicago
Firearm Injury, Injury Traumatic
Recovery Legal Care Trial
Hospital-Based Violence Intervention Programs (HVIPs) affiliated with U.S. trauma centers often focus on individual behavior modification to reduce re-victimization.
- Conditions
- Firearm Injury, Injury Traumatic, Economic Problems
- Trial name
- HVIP-MLP (NCT07764458)
- Testing
- Recovery Legal Care, HVIP Standard of Care
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Chicago
Firearm Injury, Economic Problems
Recovery Legal Care Pilot
Hospital-Based Violence Intervention Programs (HVIPs) affiliated with trauma centers in the US often focus on individual behavior modification for reduction in re-victimization.
- Conditions
- Firearm Injury, Economic Problems, Injury Traumatic
- Trial name
- HVIP-MLP (NCT06618794)
- Testing
- Recovery Legal Care, HVIP Standard of Care
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- University of Chicago
Sickle Cell Disease, Acute Chest Syndrome
Tocilizumab for Acute Chest Syndrome
The investigators are evaluating the role of a low dose of tocilizumab in treating acute chest syndrome in patients with sickle cell disease.
- Trial name
- NCT05640271
- Testing
- Tocilizumab
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Chicago
Feeding Tube, Children With Medical Complexity
Let's E.A.T.! (Eating With Assistive Technology): An Intervention to Support Children With Feeding Tubes and Tracheostomies
The overall objective of this proposal is to test an interdisciplinary intervention to support the transition to oral feeding for children with feeding tubes and tracheostomies.
- Conditions
- Feeding Tube, Children With Medical Complexity, Tracheostomy, Feeding Disorder, Infancy or Early Childhood
- Trial name
- NCT06525818
- Testing
- Tube weaning therapy intervention, Feeding Group
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Chicago
Health Related Social Needs (HRSN)
CommunityRx-Dementia
Caregivers of home-dwelling people with Alzheimer's Disease and related dementias (ADRD) are one of the most rapidly growing populations in the United States.
- Trial name
- CRx-D (NCT04146545)
- Testing
- Community Rx-Dementia "CRxD" Caregiver Resources
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Lennox Gastaut Syndrome (LGS)
EEG Dynamics in Lennox-Gastaut Syndrome Patients Undergoing Fenfluramine Treatment
This study plans to learn if certain markers found during electroencephalogram (EEG) analysis could predict fenfluramine responsiveness to give clinicians greater insight into the effectiveness of fenfluramine in people with…
- Trial name
- NCT07555171
- Testing
- fenfluramine HCl
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Chicago
Food Insecurity
CommunityRx-Hunger
CommunityRx-Hunger (CRx-H) is a hospital-based intervention that addresses food insecurity and other health-related social needs such as transportation, housing, utilities, and safety.
- Trial name
- CRx-H (NCT04171999)
- Testing
- Community Rx-Hunger (CRx-H)
- Where
- United States
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Acute Lymphoblastic Leukemia, T-cell Lymphoblastic Lymphoma
Using Text Messages to Improve Oral Chemotherapy for Adolescents and Adults With Acute Lymphoblastic Leukemia
This is a single center 2-phase study to assess effects of using text messages on adherence to oral chemotherapy for patients with acute lymphoblastic leukemia (ALL) or T-cell lymphoblastic lymphoma.
- Trial name
- NCT06446661
- Testing
- High Intensity, No Text Messagings, Low Intensity Text Messaging
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Chicago
Anorexia Nervosa
Biasing Food Value Construction
The goal of this clinical trial is to examine whether food value construction can be biased in individuals with anorexia nervosa.
- Trial name
- NCT07692945
- Testing
- Training food attributes
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Brain Injuries, Acute, Brain Trauma
BRIDGE-US: Bridging Readiness in Deployed Neurotrauma Gaps for Excellence
The purpose of this research study is to prospectively collect biospecimens, imaging, and clinical data from patients with penetrating brain injuries across high-volume PBI sites in the US (including UChicago).
- Conditions
- Brain Injuries, Acute, Brain Trauma, Penetrating Head Injury, Traumatic Brain Injury
- Trial name
- BRIDGE-US (NCT07636213)
- Testing
- Blood Sample Collection
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- University of Chicago
HIV
Leveraging Pharmacy Technicians to Advance the Reach of Modern Antiretroviral Therapy (PHARM ART) in Community Clinics
Long-acting injectable HIV medication is an important new innovation in HIV treatment, but complex delivery logistics have resulted in limited access for people with HIV (PWH).
- Trial name
- PHARM ART (NCT07553949)
- Testing
- Pharmacy-technician based model
- Volunteers
- 465 people
- Sponsor
- University of Chicago
Language Environments of Children of Low-socioeconomic Status
Thirty Million Words Home Visiting
The TMW intervention aims to foster parental behaviors that facilitate children's language emergence at a critical developmental stage, and thus will be implemented at 13-16 months of age.
- Trial name
- TMW HV RCT (NCT02216032)
- Testing
- TMW Curriculum, Nutrition Curriculum
- Where
- United States
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Sleep
Effect of Early Parent Education on Children's Sleep
The goal of this clinical trial is to learn if providing sleep information and advice to expecting parents can increase sleep duration and decrease sleep problems in infants.
- Trial name
- WISH (NCT07515534)
- Testing
- Sleep Information and Advice 1, Sleep Information and Advice 2
- Where
- United States
- Volunteers
- 391 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Peanut Allergy
Pinpoint Trial: Prebiotics IN Peanut Oral ImmunoTherapy
The purpose of this research is to gather information on the safety and efficacy of using a prebiotic as an adjunctive therapy to peanut oral immunotherapy.
- Trial name
- NCT05138757
- Testing
- Prebiotic
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Chicago
Meniscal Tear
Comparing Meniscal Repair Biologic Augmentation: Marrow Venting Procedure Versus PRP (MVP Trial)
There are no current or past RCT comparing biologic augments for meniscal repair. There is good data supporting both the use of BMVP of the intercondylar notch and intra-articular PRP injections for augmentation of meniscal…
- Trial name
- NCT04775004
- Testing
- Bone marrow venting procedure (BMVP), Platelet Rich Plasma (PRP)
- Where
- 3 sites in United States
- Volunteers
- 146 people
- Sponsor
- University of Chicago
Hidradenitis Suppurativa
Hidradenitis - an Analysis of Genetic Traits and Linkages in Families
The aim of this study is to find a genetic link or family trait connecting persons with Hidradenitis Suppurativa (HS) to each other. As a result, discover the cause and perhaps treatment for Hidradenitis Suppurativa (HS).
- Trial name
- NCT05710393
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- University of Chicago
Lymphatic Reconstruction
Objective Assessment of Outcomes Following Immediate Lymphatic Reconstruction / LYMPHA
Immediate lymphatic reconstruction (ILR) is a novel surgical approach performed at the time of initial lymph node dissection with the goal of preventing lymphedema.
- Trial name
- NCT06650592
- Testing
- All patients who were candidates for immediate lymphatic reconstruction (ILR)
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Intraoperative Awareness, General Anesthesia
Study to Determine if Patients Exposed to General Anesthesia Significant Numbers of Times Would Increase the Risk for Intraoperative Awareness.
This study will detect whether prior exposure to general anesthesia multiple times is associated with an increased incidence of awareness with explicit recall (AWR).
- Trial name
- EXPLICIT-RCL (NCT05857618)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- University of Chicago
Cardiovascular Diseases
Biobank Cardiac Surgery
Treatment strategies for cardiac surgery patients have been evolving significantly for the last decade. While clinical outcomes have been improving, there are still significant areas unexplored in these patients.
- Trial name
- NCT06747806
- Testing
- Cardiac Surgery and Procedures
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of Chicago
Diabetes Mellitus, Type 1
Using Technology to Address Disparities and Promote Healthcare Equity in Type 1 Diabetes Registry
This study is being done to see if using technology, with the help of a Patient Navigator, can help address disparities, improve outcomes, and promote healthcare equity in type 1 diabetes.
- Trial name
- EquiT1D (NCT06899984)
- Testing
- Patient Navigator
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Chicago