Clinical trials: sponsored by Yale University
Anxiety Disorder of Adolescence
Parent-Based Treatment for Adolescent Anxiety
This study aims to test the efficacy of a parent-only approach to treating anxiety disorders in adolescents: SPACE (Supportive Parenting for Anxious Childhood Emotions).
- Trial name
- NCT07219992
- Testing
- Supportive Parenting for Anxious Childhood Emotions (SPACE), Parent Educational Support (PES)
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Yale University
Anxiety Disorder of Adolescence, Avoidant / Restrictive Food Intake Disorder
Parent-Based Intervention for Childhood Avoidant/Restrictive Food Intake Disorder (ARFID)
This study aims to test the efficacy of a parent-based approach to treating Avoidant/Restrictive Food Intake Disorder (ARFID) in children, SPACE-ARFID (Supportive Parenting for Anxious Childhood Emotions, adapted for ARFID), by…
- Trial name
- NCT07916974
- Testing
- Supportive Parenting for Anxious Childhood Emotions (SPACE), Nutritional Support (NS)
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Yale University
Asthma in Children
Community Health Equity Accelerator (CHEA) Pediatric Asthma Intervention
The purpose of this pilot is to initiate an academic-community partnership and launch a multi-level intervention that includes an asthma exposure pathway (an online decision support and resource) and a health Promotora program…
- Trial name
- NCT06507943
- Testing
- Promotora Home Visit
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Yale University
RSV Infection
Real-World Effectiveness of Perinatal RSV Immunoprophylaxis
The purpose of this study is to continue evaluating how well the RSV vaccines work as they are currently being used in routine clinical practice.
- Trial name
- NCT06172660
- Testing
- Nirsevimab
- Where
- United States
- Volunteers
- 3,750 people
- Sponsor
- Yale University
Diabetes Mellitus, Type 2
Adolescent-mediated Family Diabetes Intervention: American Samoa
The goal of this project is to test the feasibility, acceptability, and preliminary efficacy of an adolescent-mediated intervention designed to improve the glycemic control and self-care practices of a parent/grandparent.
- Trial name
- NCT05356884
- Testing
- Diabetes Intervention, Leadership & Life Skills
- Where
- American Samoa
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Yale University
Mental Health Issue, COVID-19
Evaluating the Community Drum Circle
Mental health vulnerability due to stress is increased America due to disproportionate effects of social factors such as racism, poverty, education, and criminal justice sentencing.
- Trial name
- NCT06513858
- Testing
- Communal Drumming, Communal drumming recordings
- Where
- 2 sites in United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Yale University
Mental Health Issue, COVID-19
Evaluating Social Perception Dynamics
Mental health vulnerability due to stress is increased in People of African Descent (PADs) in America due to disproportionate effects of racism, poverty, education, and criminal justice sentencing.
- Trial name
- NCT06513871
- Testing
- Social perception tasks
- Where
- 2 sites in United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Yale University
Mental Health Issue, COVID-19
Evaluating the Impact of Social Music
Mental health vulnerability due to stress is increased in People of African Descent (PADs) in America due to disproportionate effects of racism, poverty, education, and criminal justice sentencing.
- Trial name
- NCT06513910
- Testing
- Music
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Yale University
Obese Adolescents
Comparison Between Gastric Band, Laparoscopic Sleeve Gastrectomy, Gastric Bypass Surgeries
Determine the short and long term safety and efficacy of the Gastric bypass , laparoscopic sleeve gastrectomy, and Gastric banding (LAGB) on severely obese adolescents.
- Trial name
- NCT02004561
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Yale University
Parent-Child Relations
Supporting Parents in Affirming Their Children's Experiences of Stigma
The purpose of this study is to develop and test two brief online writing interventions to improve parental acceptance of sexual and gender minority youth (SGMY) in the Southeast United States.
- Trial name
- SPACES (NCT05919849)
- Testing
- Brief online writing intervention, Control condition
- Where
- 4 sites in United States, Israel
- Volunteers
- 132 people
- Sponsor
- Yale University
Suicide, Suicide Prevention
Peer Delivered Youth Suicide Prevention in Nepal
South Asia has the highest suicide rate in the world with important risk profile differences from high-income settings. Investigators will conduct formative research to co-design a package of brief interventions and…
- Trial name
- NCT07680179
- Testing
- Enhanced Usual Care (EUC), Youth-focused, Peer-delivered, Family-engaged Suicide Prevention Package (YPF-SuPP)
- Where
- Nepal
- Volunteers
- 160 people
- Sponsor
- Yale University
Opioid Use Disorder, HIV Infections
Buprenorphine Integration Research and Community Health
The goal of this clinical trial is to evaluate an intervention strategy in introducing screen/evaluate/treat (SET) procedures for HIV/ hepatitis C/ and Opioid Use Disorder in Primary Care Clinics in West Virginia.
- Conditions
- Opioid Use Disorder, HIV Infections, Hepatitis C
- Trial name
- BIRCH (NCT05668780)
- Testing
- NIATx Coaching
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Yale University
Major Depression Disorder
The OBSERVE Protocol
This observational protocol is intended to provide long-term follow-up data on patients initiating or continuing treatment with either Spravato® or IV ketamine.
- Trial name
- NCT06725277
- Testing
- Spravato, IV Ketamine
- Where
- 8 sites in United States
- Volunteers
- 450 people
- Sponsor
- Yale University
PTEN Hamartoma Tumor Syndrome, Macrocephaly Autism Syndrome
PTEN Hamartoma Tumor Syndrome Pediatric Patient Registry
PtenTurkiye.org' is a national ( Turkish), web-based registry for PTEN Hamartoma Tumour ( PHTS) syndrome established in 2022. It is designed to increase awareness, gather scientific knowledge by collaboration and increase data…
- Trial name
- NCT06462430
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Yale University
Opioid Use Disorder
EMS-Initiated Buprenorphine
This is a multisite EMS study that will first conduct a sequence of pragmatic, prehospital field studies to provide preliminary feasibility, acceptability, and safety data for refinement and enhancement of a subsequent single-arm…
- Trial name
- EMS BUP (NCT07475728)
- Where
- 3 sites in United States
- Volunteers
- 495 people
- Sponsor
- Yale University
Polycystic Ovarian Syndrome in Adolescent Females, Vitamin D Deficiency
Evaluation of the Clinical and Psychological Impact of Vitamin D Replacement in Adolescent Females at Risk for Polycystic Ovarian Syndrome (PCOS)
This study is a double blind, placebo controlled, randomized trial of study subjects with PCOS and low vitamin D to 2 groups- placebo and vitamin D replacement.
- Trial name
- NCT04355572
- Testing
- Vitamin D 4000IU daily
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Yale University
New Onset Refractory Status Epilepticus, New-Onset Refractory Status Epilepticus
COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE"
The goal of this clinical trial is to find out whether two existing medications-anakinra and tocilizumab-can effectively treat a rare and life-threatening brain condition called NORSE (New-Onset Refractory Status Epilepticus).
- Conditions
- New Onset Refractory Status Epilepticus, New-Onset Refractory Status Epilepticus, Febrile Infection-Related Epilepsy Syndrome (FIRES)
- Trial name
- COMBAT-NORSE (NCT07281027)
- Testing
- Anakinra, Tocilizumab, Standard medical treatment
- Where
- 33 sites in United States, Canada and 5 more
- Volunteers
- 438 people
- Sponsor
- Yale University
Nicotine Labeling for E-cigarettes
Survey to Test the Nicotine Concentration and Nicotine Flux Labels for E-cigarettes
Current labels for the nicotine in e-cigarette/vaping products do not sufficiently convey information to the public. The aims of this study include developing and validating two new types of labels for the nicotine in vaping…
- Trial name
- NCT07553585
- Testing
- Updated Labeling
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Yale University
Inappropriate Prescribing
A Trial to Reduce Inappropriate Prescribing to Older Adults Visiting the Emergency Department
Cluster-randomized trial assessing the impact of interventions on guideline-concordant prescribing in Emergency Departments (ED).
- Trial name
- NCT07146763
- Testing
- Prescribing Feedback
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Yale University
Gaucher Disease
Advancing Integrated Therapies for Gaucher Disease
The purpose of this study is to better understand the natural history, clinical outcomes, and biological features of Gaucher disease in patients receiving standard medical care
- Trial name
- NCT07758816
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Yale University