Find a clinical trial
Neonate, Circumcision
Dilemma of Neonatal Circumcision in Egypt
The study aims to compare wound healing, wound healing complications, cosmetic outcome, and level of parental satisfaction amongst four techniques of neonatal circumcision.
- Trial name
- NCT07076992
- Testing
- Circumcision by Plastibell, Circumcision by Gomco, bone cutter circumcision with suture hemostasis (BCS),
- Where
- Egypt
- Volunteers
- 85 people
- Sponsor
- Tanta University
Coronary Artery Disease, Chest Syndrome
CT Stress Myocardial Perfusion, Fractional Flow Reserve and Angiography in Patients With Stable Chest Pain Syndromes
The purpose of the DYNAMITE trial (Dynamic CT stress myocardial perfusion, CT fractional flow reserve (FFR-CT) and coronary CT angiography for optimized treatment strategy in patients with chest pain syndromes) is to determine…
- Conditions
- Coronary Artery Disease, Chest Syndrome, Acute Myocardial Infarction, Heart Failure
- Trial name
- DYNAMITE (NCT04709900)
- Testing
- CT angiography, FFR-CT and stress CT myocardial perfusion
- Where
- Denmark
- Volunteers
- 2,000 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Eye Diseases, Healthy Volunteers
Adaptive Optics Retinal Imaging
Background: By the time diseases of the retina are detected, serious damage has often already been done. Researchers want to find better ways of viewing the retina. One way called adaptive optics may help detect problems earlier.
- Trial name
- NCT02317328
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Hematopoietic Stem Cell Transplant
Prevalence and Development of Liver Dysfunction in Hematopoietic Stem Cell Transplant
Background: Hematopoietic stem cell transplant (HSCT) is a common treatment for many cancers and other illnesses. But many people who have HSCT go on to develop liver dysfunction.
- Trial name
- NCT05722210
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Neurosurgical Patients
COMparative Performance of General Purpose Models
To compare the performance of the Eleveld models for propofol and remifentanil on neurosurgery patients admitted to intensive care with their intraoperative performance.
- Trial name
- NCT06584097
- Where
- 2 sites in Italy
- Volunteers
- 42 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Atopic Dermatitis
A Long-term Study of the Medicine Called Abrocitinib in Children Aged 2 Years and Older With Moderate to Severe Eczema
This 24-month study will assess the long-term safety and efficacy of liquid abrocitinib oral suspension with or without topical medications in children 2 years of age or older with moderate-to-severe atopic dermatitis.
- Trial name
- NCT06807281
- Testing
- Abrocitinib
- Where
- 40 sites in United States, China and 5 more
- Volunteers
- 450 people
- Sponsor
- Pfizer
Lung Disease, Pneumothorax
Study of the Disease Process of Lymphangioleiomyomatosis
Pulmonary lymphangioleiomyomatosis (LAM) is a destructive lung disease typically affecting women of childbearing age. Currently, there is no effective therapy for the disease and the prognosis is poor.
- Conditions
- Lung Disease, Pneumothorax, Tuberous Sclerosis, Lymphangioleiomyomatosis
- Trial name
- NCT00001465
- Testing
- Toshibia Aquilion One CT
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
EBV, HSV
The Natural History of Severe Viral Infections and Characterization of Immune Defects in Patients Without Known Immunocompromise
Background: Infections caused by viruses are common causes of illnesses: the common cold, many ear infections, sore throats, chicken pox, and the flu are caused by different viruses.
- Conditions
- EBV, HSV, VZV, HPV
- Trial name
- NCT01011712
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Depression Disorder, Post Traumatic Stress Disorder PTSD
The Effects of Extreme Prematurity on Parenting
In France, perinatal mental health has become a major public health issue. Maternal mental health conditions can have serious consequences, including death by suicide.
- Trial name
- PREMA-PSY (NCT07918365)
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Core Binding Factor Alpha Subunits, Hematologic Neoplasms
Stem Cell Transplantation for Participants With Germline RUNX1 Associated Blood Cancers
Background: Some blood cancers can be caused by germline variants (changes) in a person s RUNX1 gene. Germline variants are genetic inherited changes a person is born with.
- Conditions
- Core Binding Factor Alpha Subunits, Hematologic Neoplasms, Leukemia, Lymphoma
- Trial name
- NCT07524530
- Testing
- Cyclophosphamide, Busulfan, Fludarabine
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- National Cancer Institute (NCI)
Autism Spectrum Disorder, Autism
Transcranial Magnetic Stimulation for Restricted and Repetitive Behavior in ASD
Investigating the efficacy of a form of TMS called theta-burst stimulation for restricted and repetitive behavior in ASD.
- Conditions
- Autism Spectrum Disorder, Autism, Asperger Syndrome
- Trial name
- TMS for ASD (NCT04532424)
- Testing
- Transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Stanford University
Analysis of Retrospectively Collected MRI Referral Data
Automated Vetting and Protocolling of MRI Examinations
Background Vetting and assigning of protocols to MRI scan requests are usually carried out by radiologists and radiographers. This way is both time-consuming and prone to error.
- Trial name
- AutoProMpt (NCT07918313)
- Testing
- No Intervention: Observational Cohort
- Volunteers
- 900,000 people
- Sponsor
- Edozie Iweka
Epilepsy, Cancer
Tumor Related Epilepsy
Background: Some people with brain tumors have seizures related to the tumor. This is called tumor-related epilepsy. Usually brain tumors are treated by removing as much of the brain tumor as possible without causing problems.
- Conditions
- Epilepsy, Cancer, Brain Neoplasm
- Trial name
- NCT02639325
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Severe Preeclampsia
Furosemide vs Placebo in Severe Preeclampsia Postpartum
This randomized, double-blind, placebo-controlled trial evaluates whether oral furosemide 40 mg, initiated 12 hours postpartum, reduces hospital length of stay compared to placebo (folic acid 5 mg) in postpartum women with severe…
- Trial name
- FUROPE (NCT07648251)
- Testing
- Furosemide, Folic Acid 5 MG
- Where
- Honduras
- Volunteers
- 186 people
- Sponsor
- Universidad Nacional Autonoma de Honduras
Development Coordination Disorder, Motor Disabilities
Evaluation of Catching Skills in Preschoolers With Motor Difficulties
This research project investigates the development of predictive and online motor control in preschool-aged boys with typical development and those with motor difficulties, specifically children at risk for Developmental…
- Trial name
- NCT07028762
- Where
- Czechia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Masaryk University
Healthy Volunteers
Collection and Analysis of Blood, Bone Marrow, and Buccal Mucosa Samples From Healthy Volunteers
The Hematology Branch of the National Heart, Lung, and Blood Institute is doing a variety of laboratory research experiments that require blood and tissue samples from healthy volunteers.
- Trial name
- NCT00442195
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Neoplasms, Physical Therapy Modalities
Impact of Physical Therapy Intervention on Foot and Ankle Function
This research study will investigate the effect of physical therapy intervention on the function of the foot and ankle in children and adolescents with cancer not involving the brain or spinal cord.
- Conditions
- Neoplasms, Physical Therapy Modalities, Survivorship
- Trial name
- NCT04930406
- Testing
- Physical therapy
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Cardiac Abnormalities, Nutrient Intake
Early Nutrition and Heart Structure and Function in Preterm Infants During the First Year of Life
Preterm infants are babies born before 37 completed weeks of pregnancy. Early nutrition is important for their growth and development, and it may also be associated with how their heart develops and functions during infancy.
- Trial name
- NCT07892209
- Testing
- echocardiography
- Volunteers
- 80 people
- Sponsor
- Assiut University
Development Disorder, Child, Developmental Disability
A Center Based Early Intervention Program For Preschoolers With Developmental Disorders
The purpose of this study is to examine the effectiveness of a 12-week early intervention program that will include 12 weekly hours in an intensive center-based preschool environment or in the home to treat social communication…
- Conditions
- Development Disorder, Child, Developmental Disability, Development Delay, Autism Spectrum Disorder
- Trial name
- NCT04026386
- Testing
- Center Based or In Home Early Intervention Program
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Stanford University
CLIFAHDD, Congenital Contractures of the Limbs and Face, Hypotonia, and Developmental Delay
Aprepitant for the Treatment of CLIFAHDD
There are no drug treatments for individuals with Congenital Contractures of the Limb and Face, Hypotonia, and Developmental Delay (CLIFAHDD), an ultra-rare and severe neurodevelopmental disease.
- Conditions
- CLIFAHDD, Congenital Contractures of the Limbs and Face, Hypotonia, and Developmental Delay, NALCN Channelopathy, Ataxia - Other
- Trial name
- NCT07845825
- Testing
- Aprepitant Powder for Oral Suspension
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
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