Find a clinical trial
Dental Crowding
Accuracy and Time Efficiency of AI Versus Manual Segmentation in Adult Crowding Using Aligner Software
The purpose of this study is to evaluate how accurately and quickly artificial intelligence (AI) can separate individual teeth from digital dental scans of adults with dental crowding.
- Trial name
- AI-MAS (NCT07919652)
- Testing
- Automated tooth segmentation and manual segmentation
- Where
- Egypt
- Volunteers
- 155 people
- Sponsor
- Dina ahmed
Diabetes (Insulin-requiring, Type 1 or Type 2), Pediatric Diabetes
A Novel Miniature Equine-Assisted Diabetes Education Program for Youth: Evaluating the Diabetes Equine Empowerment Program (DEEP).
The Diabetes \& Equine Empowerment Program (DEEP) is a research study evaluating a novel diabetes education program that combines hands-on interactions with miniature horses and evidence-based diabetes self-management education…
- Conditions
- Diabetes (Insulin-requiring, Type 1 or Type 2), Pediatric Diabetes, Diabetes (DM)
- Trial name
- DEEP (NCT07822555)
- Testing
- Diabetes & Equine Empowerment Program (DEEP)
- Volunteers
- 50 people
- Sponsor
- Nemours Children's Clinic
First Episode Psychosis
Disengagement in CSC: Identifying Those at Risk and Addressing Their Needs
Maintaining treatment engagement is critical for first episode psychosis patients to experience gains possible with coordinated specialty care (CSC).
- Trial name
- NCT04005378
- Testing
- CSC Step-down intervention, Usual Care
- Where
- 3 sites in United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Autism Spectrum Disorder (ASD), Autism
Trial of Center-Based Early Start Denver Model vs. Pivotal Response Treatment in Children With Autism
The goal of this study is to compare two well-established early autism interventions, Early Start Denver Model (ESDM) and Pivotal Response Treatment (PRT), to better understand which approach is most effective for improving…
- Trial name
- NCT07522190
- Testing
- Early Start Denver Model (ESDM), Pivotal Response Treatment (PRT), Developmental Reciprocity Treatment (DRT)
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Stanford University
Infection, Inflammation
Diagnosis and Management of Inflammatory and Infectious Diseases
This protocol is being established to cover the evaluation of patients with inflammatory and/or infectious diseases which are not covered under previously existing protocols.
- Trial name
- NCT00557726
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
NSCLC
Stereotactic Body Radiotherapy for the Treatment of OPD
HALT is a phase II, randomised multi-centre study with integrated seamless continuation to phase III trial following acceptable safety and feasibility assessment.
- Trial name
- HALT (NCT03256981)
- Testing
- SBRT, TKI
- Where
- 29 sites in France, Italy and 3 more
- Volunteers
- 113 people
- Sponsor
- Institute of Cancer Research, United Kingdom
IPEX
CD4^LVFOXP3 in Participants With IPEX
This first-in-human, Phase 1 clinical trial will test the feasibility of the manufacturing and the safety of the administration of CD4^LVFOXP3 in up to 30 evaluable human participants with IPEX and evaluate the impact of the…
- Trial name
- NCT05241444
- Testing
- CD4^LVFOXP3
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Bacchetta, Rosa, MD
Bimaxillary Protrusion, Class II Div 1 Malocclusion
Discision as Acceleration Method in Canine Retraction in Orthodontics With Aligner and Fixed Appliances in Young Adults a Split Mouth Study
The effectiveness of discision in accelerating orthodontic canine retraction will be evaluated during clear aligner therapy and during conventional fixed orthodontic appliances.
- Trial name
- NCT07920276
- Testing
- Discision
- Where
- 2 sites in Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Immune Defects
Detection and Characterization of Host Defense Defects
This protocol is designed to evaluate selected patients with documented recurrent or unusual infections and their family members for clinical and laboratory correlates of immune abnormalities.
- Trial name
- NCT00001355
- Where
- United States
- Volunteers
- 3,600 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Critical Illness
Renal Replacement Anticoagulant Management
Observational comparative effectiveness study of individual patient data using interrupted time series analysis techniques of linked data sources to establish clinical and health economic effects of moving from systemic heparin…
- Trial name
- RRAM (NCT03545750)
- Where
- United Kingdom
- Volunteers
- 85,000 people
- Sponsor
- Intensive Care National Audit & Research Centre
Yellow Fever Immunization
A Phase III Control Study of the Safety and Immunogenicity of vYF in Pediatric Population
The purpose of this study is to determine whether vYF (investigational vaccine) is safe and can help the body to develop antibodies (immunogenicity) compared with Stamaril vaccine and YF-VAX vaccine (both licensed vaccines) and…
- Trial name
- NCT07103148
- Testing
- Yellow fever vaccine (live), Measles, combinations with mumps and rubella, live attenuated
- Where
- 15 sites in Honduras, Mexico and 1 more
- Volunteers
- 2,440 people, healthy volunteers welcome
- Sponsor
- Sanofi
Epidermolysis Bullosa Simplex
Filsuvez in Moderate-to-Severe Epidermolysis Bullosa Simplex
This pilot study will look at whether the topical Birch Triterpenes (Filsuvez) gel is safe and helpful for adults and children 6 months of age and older who have moderate to severe epidermolysis bullosa simplex (EBS).
- Trial name
- FILS-EBS (NCT07756138)
- Testing
- Filsuvez
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Stanford University
Atopic Dermatitis, Psoriasis
Cosmetic Efficacy Evaluation of Hydraporin AI Cream in Individuals With Atopic Dermatitis and Psoriasis
The goal of this clinical trial is to evaluate the cosmetic efficacy and safety of an investigational cream in participants with atopic dermatitis or psoriasis.
- Trial name
- NCT07918560
- Testing
- Investigational cream
- Where
- Brazil
- Volunteers
- 42 people
- Sponsor
- Brainfarma Industria Química e Farmacêutica S/A
type1diabetes
Diabetes in African Youth
This RCT aims to improve T1D care in East African children and young adults by testing the hypothesis that enabling patients to continuously monitor glucose levels with flash CGM technology will improve glucose time-in-range…
- Trial name
- NCT05454176
- Testing
- Libre 2, Device for SMBG and Libre Pro
- Where
- United States
- Volunteers
- 188 people
- Sponsor
- University of Minnesota
Obesity, Diabetes
Evaluation of the Clinical Spectrum of Diabetes and Obesity in Youth and Adults
Background: Diabetes and obesity are chronic diseases. They can affect blood flow and how the body processes nutrients, and complications over time can lead to early death.
- Conditions
- Obesity, Diabetes, Metabolic Disorders
- Trial name
- NCT07388537
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Visual Dependence, Postural Control
Effects of Virtual Reality-Based Optokinetic Stimulation Added to Neuromuscular Training in Basketball Players
This study will investigate whether adding virtual reality-based optokinetic stimulation to neuromuscular training improves jump-landing movements, balance, and performance during a visually cued movement task in basketball…
- Conditions
- Visual Dependence, Postural Control, Jump-Landing Biomechanics
- Trial name
- NCT07918599
- Testing
- Neuromuscular Training, Virtual Reality-Based Optokinetic Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Cochlear Hearing Loss
Retrospective Analysis of Speech Performance Using the HiRes Ultra and HiRes Ultra 3D Cochlear Implant
This is a retrospective study designed to collect speech perception results for HiRes Ultra CI and HiRes Ultra 3D CI users as measured in the clinical routine and to confirm the performance of these devices.
- Trial name
- NCT06301581
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Advanced Bionics AG
Fever
Fever Observational Study
To inform the feasibility of conducting a study to test different temperature thresholds at which clinicians deliver interventions to reduce fever (i.e.
- Trial name
- NCT03028818
- Where
- United Kingdom
- Volunteers
- 3,960 people
- Sponsor
- Intensive Care National Audit & Research Centre
Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8
A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab
This phase III trial compares the effect of adding immunotherapy (brentuximab vedotin and nivolumab) to standard treatment (chemotherapy with or without radiation) to the standard treatment alone in improving survival in patients…
- Trial name
- NCT05675410
- Testing
- Biospecimen Collection, Bleomycin Sulfate, Brentuximab Vedotin
- Where
- 419 sites in United States, Canada and 1 more
- Volunteers
- 1,875 people
- Sponsor
- National Cancer Institute (NCI)
Parent Child Relationship, Parenting Intervention
The New Beginnings Podcast: Brief Audio Intervention for Parents From Divorced and Separated Families
The goal of this study is to learn if the New Beginnings Podcast can help children whose parents are going through a divorce or separation.
- Conditions
- Parent Child Relationship, Parenting Intervention, Parenting Behaviour, Interparental Conflict
- Trial name
- NBP-P (NCT07529548)
- Testing
- New Beginnings Podcast Program, No Interventions
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Charla Aubrey Rhodes
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