Clinical trials: Phase not applicable, open to volunteers
Physical Activity, Body Image
THE EFFECTS OF GAME-BASED EXERCISE PROGRAMS
Studies comparing aerobic exercise with virtual reality or video game technologies to traditional games and classical exercise have been conducted in healthy adolescents, but no studies comparing virtual reality and video game…
- Conditions
- Physical Activity, Body Image, Exercise Perception, Balance
- Trial name
- NCT07660822
- Testing
- Conventional Physical Exercise Program, Xbox Console-Based Exercise Program, Virtual Reality-Based Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Gaziantep Islam Science and Technology University
Cerebral Palsy
Feasibility of a Robot-Guided Active Play Intervention for Children With Cerebral Palsy
Cerebral palsy can make it difficult for children and adolescents to participate consistently in enjoyable physical activity. This study will examine whether a small humanoid robot called NAO can deliver a short, story-based…
- Trial name
- REACT (NCT07842328)
- Testing
- Humanoid Robot-Guided Active Play Intervention
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
Adverse Childhood Experience, Depression / Major Depressive Disorder
Preventive and Personalized Digital Emotion Regulation Skills Intervention to Reduce Depression and Anxiety in Youths With Adverse Childhood Experiences
The present study aims to determine whether a personalized digital psychoeducation intervention (active intervention group) is more effective than self-monitoring of one's mood (control group) in reducing emotion regulation…
- Conditions
- Adverse Childhood Experience, Depression / Major Depressive Disorder, Anxiety Depression, Anxiety
- Trial name
- PREVENT-DERS (NCT07921446)
- Testing
- Lifestyle psychoeducation intervention, Personalized digital psychoeducation intervention on emotion regulation
- Volunteers
- 140 people
- Sponsor
- Institute of Mental Health, Singapore
Suicidal Ideas, Suicidal Ideation
A Pre-post Study of a Lethal Means Safety Planning Intervention for Youth at Elevated Suicide Risk in the Emergency Department
The purpose of this study is to test whether a lethal means safety planning intervention, TEEN LENS ED, is acceptable to teens at elevated suicide risk and their caregivers in the Emergency Department.
- Conditions
- Suicidal Ideas, Suicidal Ideation, Suicidal Thoughts, Firearm Safety
- Trial name
- TEEN LENS ED (NCT07916792)
- Testing
- TEEN LENS, Usual Care
- Volunteers
- 200 people
- Sponsor
- University of Colorado, Denver
Diplegic Cerebral Palsy
Additional Effects on tDCS With AOT on Lower Limb Functions on Children With Diplegic CP
The goal of this clinical trial is to evaluate the therapeutic effects of combining active transcranial direct current stimulation (tDCS) with Action Observation Therapy (AOT) in pediatric patients diagnosed with spastic Cerebral…
- Trial name
- tDCS (NCT07921095)
- Testing
- Action Observation Therapy, Transcranial Direct Current Stimulation
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Drug-Resistant Epilepsy
Clinical Trial of SEEG for Drug-resistant Epilepsy
This trial evaluates the safety and efficacy of SEEG recording and functional mapping for patients with drug-resistant epilepsy.
- Trial name
- SEEG-DRE (NCT07923058)
- Testing
- SEEG RF-TC
- Where
- 17 sites in China
- Volunteers
- 99 people
- Sponsor
- Beijing Pins Medical Co., Ltd
Brain Death, Respiration, Artificial
Miniature In-line Respirator
This first-in-human pilot study will test an investigational miniature breathing device called the Hope inVent. The device is a small, single-use, in-line respirator that connects to a breathing tube and uses compressed oxygen to…
- Trial name
- NCT07768215
- Testing
- Hope inVent
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Apnea of Prematurity
nCPAP-NAVA-Backup Versus Standard nCPAP for Severe Apnea in Preterm Infants ≤28 Weeks
The goal of this clinical trial is to determine whether nasal continuous positive airway pressure (nCPAP) with neurally adjusted ventilatory assist (NAVA) backup ventilation (nCPAP-NAVA-backup mode) reduces the rate of severe…
- Trial name
- NAVAPNEA (NCT07923604)
- Testing
- nCPAP-NAVA-backup mode, nCPAP mode
- Where
- Switzerland
- Volunteers
- 25 people
- Sponsor
- University Hospital, Geneva
Congenital Heart Disease (CHD)
Autologous Thymus Transplant in Children With Congenital Heart Disease: A Pilot Study
This pilot study will look at whether putting back a child's own thymus tissue during heart surgery is safe and may help support the immune system in children with congenital heart disease (CHD).
- Trial name
- ATTT (NCT07799259)
- Testing
- Autologous Thymus Transplant
- Volunteers
- 10 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Cerebral Palsy
Sensory Integration Therapy vs Conventional Physical Therapy in Children With Mixed Cerebral Palsy
The study aims to compare Sensory Integration Therapy (SIT) with Conventional Physical Therapy (CPT) for improving gross motor function in children aged 4-10 years with mixed cerebral palsy.
- Trial name
- NCT07921069
- Testing
- Sensory Integration Therapy, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
Pediatric Acute Respiratory Failure
Regional Lung Ventilation During Prone Position in in Intubated Children
Mechanical ventilation can lead to pulmonary, diaphragmatic, and hemodynamic complications due to an increase in global and regional transpulmonary pressure.
- Trial name
- ChildProne-EIT (NCT07921745)
- Testing
- Thoracic electric impedance tomography to assed regional ventilation, Positive end-expiratory pressure (PEEP) trial titration, Collection of clinical Data
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Reading Difficulties, Behavioral Problems
Study of Psychoeducation and Reading for Kids (SPARK)
The Study of Psychoeducation and Reading for Kids (SPARK) is a trial of a broad-spectrum psychoeducational tutoring intervention.
- Conditions
- Reading Difficulties, Behavioral Problems, Emotional Problems
- Trial name
- SPARK (NCT07922876)
- Testing
- Psychoeducational tutoring
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- State University of New York - Upstate Medical University
Attention Deficit Hyperactivity Disorder (ADHD)
Micronutrient Supplementation and Chronotherapy in Children With ADHD
Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental condition in children that can affect attention, behavior, learning, and daily functioning.
- Trial name
- SMART-ADHD (NCT07922252)
- Testing
- Broad-spectrum multivitamin and mineral supplementation, Chronotherapy-Based Lifestyle Guidance
- Where
- Malaysia
- Volunteers
- 120 people
- Sponsor
- UCSI University
Autism Spectrum Disorder
Sensory-integration Therapy Verses Augumented Reality-based Training in ASD
To determine and contrast the effects of Sensory Integration Therapy (SIT) and Augmented Reality-Based Training (AR) on gross motor skills, assessed using the Test of Gross Motor Development-Third Edition (TGMD-3), in children…
- Trial name
- NCT07921199
- Testing
- Augumented Reality-Based Training, Sensory-Integration Therapy
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Pre-myopia, Myopia
Managing Premyopia in Chinese Children Using Artificial Intelligence Assisted Defocus Incorporated Multiple Segments Based Spectacle Lens: a Randomized Controlled Clinical Trial
Pre-myopia refers to a condition in which children have not yet developed myopia but exhibit insufficient hyperopic reserve (≤ +0.75 D).
- Trial name
- NCT07765550
- Testing
- Artificial Intelligence Assisted DIMS based Spectacle Lens, Smartwatches
- Where
- China
- Volunteers
- 128 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Risk of Depression and Anxiety
Cultural Adaptation of an Online Parenting Intervention to Reduce the Risk of Depression and Anxiety in Adolescents
Depression and anxiety are common mental health problems among adolescents and can affect their relationships, education, physical health and everyday lives.
- Trial name
- PiP_ Pakistan (NCT07790835)
- Testing
- Partners in Parenting
- Where
- Pakistan
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Living and Learning
First Aid, Health Education in Schoolchildren
Mobile Game-Based Versus Classic First Aid Education in Adolescents: Randomized Controlled Trial
The goal of this three-arm, stratified randomized controlled trial is to learn whether a mobile serious game improves first aid knowledge in high school students aged 14 to 17 years compared with classic first aid education and…
- Conditions
- First Aid, Health Education in Schoolchildren, Adolescent Health
- Trial name
- CanKurtaranRCT (NCT07922057)
- Testing
- Mobile serious game-based first aid education, Classic first aid education, Nutrition education on food label reading (attention control)
- Where
- Turkey (Türkiye)
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Pregnancy Related, Hypertension
Testing Implementation Strategies to Support Clinic Fidelity to an Outpatient Hypertension Bundle
The goal of this clinical trial is to test an approach to improve care for pregnant and post-partum patients with high blood pressure.
- Trial name
- ACHIEVE (NCT06002165)
- Testing
- Usual Care, ACHIEVE Multi-component Implementation Strategy
- Where
- 8 sites in United States
- Volunteers
- 5,677 people
- Sponsor
- University of North Carolina, Chapel Hill
Spastic Cerebral Palsy
Telerehabilitation Compared With Clinic-Based Physiotherapy in Children With Spastic Cerebral Palsy
This randomized controlled trial will compare structured telerehabilitation with clinic-based physiotherapy in children aged 4-12 years with spastic cerebral palsy.
- Trial name
- NCT07921147
- Testing
- Structured Telerehabilitation Program, Clinic-Based Physiotherapy Program
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Preterm Birth, Enterocolitis, Necrotizing
Study of the Influence of Intraperitoneal Insufflation of CO2 by Laparoscopy on the Short-term Evolution of Premature Infants With Ulcerative Necrotizing Enterocolitis
Ulcerative-necrotizing enterocolitis (ECUN) is an infectious and inflammatory disease of the digestive tract, which can lead to intestinal necrosis or perforation.
- Trial name
- NECO2 (NCT05882448)
- Testing
- laparotomy, Laparoscopy
- Where
- 2 sites in France
- Volunteers
- 54 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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