Clinical trials: sponsored by Aesculap AG
Hyperkyphosis, Hyperlordosis
Post-Market Clinical Follow-Up Study on the Safety and Performance of Ennovate® Complex
Multicenter, multinational Post-Market Clinical Follow-Up (PMCF) study on the safety and performance of Ennovate® Complex - A prospective, pure data collection of all Ennovate® scoliosis patients in selected centers (not…
- Conditions
- Hyperkyphosis, Hyperlordosis, Congenital Scoliosis, Neuromuscular Scoliosis
- Trial name
- COSINE (NCT05281757)
- Testing
- posterior stabilization for the cervical spine
- Where
- 2 sites in Czechia, Malaysia
- Volunteers
- 200 people
- Sponsor
- Aesculap AG
Contusions, Incision
Dermal Wound Closure Using Silkam®
Assessment of performance of Silkam® suture material for skin closure. A prospective, single center, single arm, observational study in daily practice.
- Conditions
- Contusions, Incision, Laceration
- Trial name
- DERMASILK (NCT05225714)
- Where
- Spain
- Volunteers
- 161 people
- Sponsor
- Aesculap AG
Cartilage Disease
Non-interventional Study With NOVOCART® 3D for the Treatment of Cartilage Defects of the Knee in Pediatric Patients
Prospective, multicenter, single-arm non-interventional study to evaluate the efficacy, safety and health economics of NOVOCART 3D in the Treatment fo cartilage defects of the knee in pediatric patients wieh closed epiphyseal…
- Trial name
- JUNOVO (NCT04186208)
- Testing
- NOVOCART 3D
- Where
- 6 sites in Germany
- Volunteers
- 42 people
- Sponsor
- Tetec AG
Degenerative Disc Disease, Spondylolisthesis
Quintex® Follow-up After One Year Minimum
Prospective study, not randomised, non-interventional, monocentric, investigating an intended patient cohort of 60 patients already operated on the cervical spine due to degenerative disc disease of the cervical spine down to the…
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Trauma, Spinal Stenosis
- Trial name
- Quintex (NCT04489394)
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Aesculap AG
Eye Diseases
Dafilon® Suture Material in Patients Undergoing Ophthalmic Surgery
This is an observational, retrospective postmarket clinical follow-up study and includes all patients who underwent any ophthalmic surgery using Dafilon® suture in the selected centres between 2018 and 2020, therefore no sample…
- Trial name
- OPHTHADA (NCT05968443)
- Testing
- ophthalmic surgery
- Where
- Malaysia
- Volunteers
- 200 people
- Sponsor
- Aesculap AG
Laceration of Skin, Injury Skin
Assessment of DAFILON® Suture Material for Skin Closure
In this non-interventional study (NIS) a polyamide non-absorbable suture (Dafilon®) will be evaluated for skin closure in adult and pediatric patients.
- Trial name
- SKINDA (NCT04617041)
- Where
- 2 sites in Germany, Spain
- Volunteers
- 115 people
- Sponsor
- Aesculap AG
Abdominal Wall Defect, Ventral Hernia
Clinical Study on the Safety of SAFIL® MESH
Observational, Retrospective, Multi-center Clinical Study on the Safety of SAFIL® MESH in Patients Undergoing Reinforcement of Soft Tissues After Abdominal Wall Surgery or Other Fascial Defects
- Conditions
- Abdominal Wall Defect, Ventral Hernia, Abdominal Hernia, Fascial Hernia
- Trial name
- SAFIL_MESH (NCT04947202)
- Testing
- Hernioplasty
- Where
- 2 sites in Spain
- Volunteers
- 152 people
- Sponsor
- Aesculap AG
Pediatric and Adult: Mucosal Closure in Facial and Oral Surgery, Pediatric and Adult: Skin Closure (Dermal Sutures)
Prospective, International Monosyn® Quick - Non Interventional Study
The Monosyn® Quick non-interventional study (NIS) has been designed to implement an action within the framework of a proactive post-market surveillance system.
- Conditions
- Pediatric and Adult: Mucosal Closure in Facial and Oral Surgery, Pediatric and Adult: Skin Closure (Dermal Sutures), Women: Episiotomy, Pediatric: Urological Interventions (Circumcision, Phimosis Etc.)
- Trial name
- PRIMOQ (NCT03355001)
- Testing
- Monosyn® Quick
- Where
- 3 sites in Germany
- Volunteers
- 153 people
- Sponsor
- Aesculap AG
Cartilage Disease
Non-interventional Study With NOVOCART® Inject in the Reconstruction of the Knee Cartilage Defects
Retrospective non-interventional study to evaluate safety and efficacy of NOVOCART® Inject in patients with full-thickness cartilage defects in the knee joint.
- Trial name
- RENOVO (NCT02941120)
- Where
- 7 sites in Germany
- Volunteers
- 245 people
- Sponsor
- Tetec AG
Cartilage Diseases
Non-Interventional Study to Evaluate Safety and Efficacy of NOVOCART 3D in Patients With Cartilage Defects
Non-interventional study to evaluate safety and efficacy of NOVOCART 3D in adult and adolescent patients with full thickness cartilage defects after the treatment with NOVOCART 3D.
- Trial name
- NISANIK (NCT02348697)
- Testing
- NOVOCART 3D
- Where
- 9 sites in Germany
- Volunteers
- 81 people
- Sponsor
- Tetec AG
Hydrocephalus
Guided Application of Ventricular Catheters
Failure of ventricular catheters remains a significant problem in patients with hydrocephalus. The purpose of this study is to determine whether the use of a simple instrument assisted by a smart phone application software can…
- Trial name
- GAVCA (NCT01811589)
- Testing
- Thomale-Guide, Free-hand
- Where
- 9 sites in Germany
- Volunteers
- 144 people
- Sponsor
- Aesculap AG
Skin Closure
PMCF-study Using Novosyn® Quick Suture Material for Skin Closure
The aim of this study is to show that the performance of Novosyn® Quick suture material is comparable with other suture material used for skin closure.
- Trial name
- SKINNOQ (NCT02680886)
- Testing
- Novosyn® Quick
- Where
- 2 sites in France, Germany
- Volunteers
- 100 people
- Sponsor
- Aesculap AG
Survival, Prosthesis
Prevision® PMCF Study
Monocentric, non-interventional Post-Market Clinical Follow-Up (PMCF) Study on past implantations of the Prevision® prosthesis; the survival rate of the Prevision® prosthesis shall be evaluated and compared to literature results…
- Trial name
- NCT03510065
- Testing
- Prevision®
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Aesculap AG
Osteoarthritis, Metal Ion Levels
Serum Metal Ion Concentration After Total Knee Arthroplasty (TKA)
All metal implants release metal ions because of corrosion. Total knee arthroplasty implants have large metal surface areas and therefore substantial potential for corrosion.
- Trial name
- NCT00862511
- Testing
- Coated Total Knee Arthroplasty, Standard Total Knee Arthroplasty
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Technische Universität Dresden
Osteoarthritis, Rheumatoid Arthritis
Minimally Invasive Versus Conventional Approaches in Navigated Total Knee Arthroplasty (TKA)
50 patients are randomized to two groups who receive a navigated knee prosthesis. Aim of the study is a comparison between a minimally invasive and a conventional approach.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Arthritis
- Trial name
- NCT00839020
- Testing
- Navigated TKA with a minimally invasive approach, Navigated TKA with a conventional approach
- Where
- Germany
- Volunteers
- 26 people
- Sponsor
- Aesculap AG
Appendicitis
TICAP - Titanium Clips for Appendiceal Stump Closure
Laparoscopic appendectomy is progressively accepted as the treatment of choice for acute appendicitis. Although the surgical technique of laparoscopic appendectomy has been well established, some controversy exists regarding the…
- Trial name
- TICAP (NCT01734837)
- Testing
- DS-Ligature Clip
- Where
- 9 sites in United States, Germany
- Volunteers
- 390 people
- Sponsor
- Aesculap AG
Total Hip Arthroplasty
TRJ Post Market Clinical Follow Up
Clinical and radiological 2 years results of TRJ® Hip Stem.
- Trial name
- NCT02019862
- Testing
- TRJ® Total Hip Arthroplasty
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Aesculap AG
Sternum Wound Infection, Nonunion of Fracture of Sternum
Sternal Closure With STERNUMFIX in Patients With High Risk
The primary objective is to establish if the SternumFix System improves sternal closure. The study should test the hypothesis that in a high risk patient population with increased risk for the development of sternal wound…
- Trial name
- STEPHIX (NCT01408745)
- Testing
- Sternumfix, steel wire
- Where
- 4 sites in Germany, Switzerland
- Volunteers
- 166 people
- Sponsor
- Aesculap AG