Clinical trials: sponsored by Beijing Tongren Hospital
Pre-myopia
The Efficacy of a Polarized Folded Optical Path-based Reading-writing Desk for Myopia Prevention and Control in Pre-myopic Children
The goal of this clinical trial is to evaluate the efficacy and safety of the polarized folded optical path reading and writing device in myopia prevention onset in 5-10 year old children with pre myopia.
- Trial name
- NCT07914114
- Testing
- Polarized folded optical path reading and writing device, Eye-care desk lamp and desk posture corrector
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Soft Tissue Sarcoma
Preliminary Clinical Study of Entinostat in Children With Malignant Soft Tissue Sarcoma Harboring PAX-family Gene Abnormalities
Pediatric soft tissue sarcomas (STS) are a group of malignant tumors originating from primitive mesenchymal tissues and account for approximately 7% of childhood cancers.
- Trial name
- NCT07888114
- Testing
- Entinostat, VAC/VTC chemotherapy
- Where
- China
- Volunteers
- 16 people
- Sponsor
- Beijing Tongren Hospital
High Myopia
SmoothCore Orthokeratology Plus M.O.V.E. Lenses vs. M.O.V.E. Lenses Alone for Myopia Control in Children With High Myopia
This clinical trial aims to determine whether a combination of overnight orthokeratology lenses and daytime myopia-control spectacles is more effective than myopia-control spectacles alone in slowing myopia progression and…
- Trial name
- NCT07854366
- Testing
- SmoothCore Technology Orthokeratology Combined with M.O.V.E. Lenses, M.O.V.E. Lenses Alone
- Volunteers
- 100 people
- Sponsor
- Beijing Tongren Hospital
Myopia
Screening for Hyperopic Reserve in Kindergarten
Screening for hyperopic reserve among senior kindergarten children is an important population-based eye health measure. Hyperopic reserve refers to physiological hyperopia in young children, which acts as a natural buffer against…
- Trial name
- NCT07851532
- Where
- China
- Volunteers
- 134,000 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Large B-Cell Lymphoma (LBCL)
CD19/ CD22 Bispecific CAR-T Cell Therapy for Relapsed/ Refractory Large B-cell Lymphoma
CAR-T cell therapy targeting CD19 has been shown to be effective in heavily-pretreated B-cell ALL or NHL, but relapses post-CAR-T are common, and CD19 antigen loss is one of the reasons.
- Trial name
- NCT07461831
- Testing
- CD19/CD22 bispecific CAR-T cells
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Beijing Tongren Hospital
Congenital Microtia
Case Management for Microtia
The aim of this study is to develop an intelligent, full-course case management model for patients with microtia, enabling them to receive continuous, individualized nursing and health management services across the stages from…
- Trial name
- NCT07846345
- Testing
- Microtia case-management platform
- Where
- China
- Volunteers
- 188 people
- Sponsor
- Jing Xu
Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
China CRSwNP Registry Study
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a long-lasting inflammatory disease of the nose and sinuses that can cause nasal blockage, loss of smell, nasal discharge, facial discomfort, sleep problems, and reduced…
- Trial name
- POLARIS (NCT07795658)
- Testing
- Routine Clinical Care for CRSwNP
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Beijing Tongren Hospital
Myopia, Prevention and Control
Effectiveness of Digital Defocus Vision Training With Low-Concentration Atropine on the Prevention and Control of Myopia in Children: A Clinical Study
Based on existing theories of myopia development and progression, our preliminary work has leveraged the features of virtual reality (VR) technology to digitally simulate myopic defocus signals through image-based emulation.
- Trial name
- NCT07724210
- Testing
- For the experimental group,Virtual reality-based digital defocus training combined with 0.02% atropine eye drops, For the control group, one drop of 0.02% atropine eye drops was instilled into each eye at bedtime daily, combined with full-time wear of fully corrected multi-zone positive optical defocus (DIMS) spe
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Amblyopia, Visual Training
A Randomized Controlled Trial of Autostereoscopic 3D Vision Therapy for Amblyopia
The goal of this clinical trial is to learn if an autostereoscopic 3D amblyopia training system works to improve vision in children and adolescents with amblyopia.
- Conditions
- Amblyopia, Visual Training, Visual Functions, Visual Health
- Trial name
- NCT07709832
- Testing
- Autostereoscopic 3D Training, Conventional Patching
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Beijing Tongren Hospital
Low Vision in Children
Research and Development of Reading Visual Aids for Low-Vision Individuals Based on Virtual Reality Technology
Low vision substantially impairs reading ability and educational participation in adolescents. Existing assistive technologies, including optical magnifiers and electronic visual aids, are often limited by fragmented system…
- Trial name
- NCT07703449
- Testing
- VR-Based Intelligent Reading Aid, Natural Vision Reading (No Assistive Device)
- Where
- China
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
no Obvious Abnormalities, Diabetic Retinopathy (DR)
Retinal Clinical Assessment With AI-derived Quantitative Information
This randomized controlled trial evaluates whether providing clinicians with AI-derived quantitative retinal information improves the quality and efficiency of retinal clinical assessment.
- Conditions
- no Obvious Abnormalities, Diabetic Retinopathy (DR), AMD, Cup-to-disc Ratio Bigger Than 0.5
- Trial name
- NCT07291960
- Testing
- AI-derived retinal quantitative information-assisted reporting
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Emergence Agitation
Auricular Acupressure for Reducing Postoperative Emergence Agitation in Preschool Children
This study investigates whether auricular acupressure can reduce postoperative emergence agitation among preschool children following adenoidectomy.
- Trial name
- NCT07472764
- Testing
- Auricular acupressure
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Beijing Tongren Hospital
High Myopia, Low Concentration Atropine
Low Concentration Atropine Combined With Soft Contact Lens in Controlling Myopia Progression in Children With High Myopia
Peripheral contact lens in controlling myopia progression in high myopia children（PAM）is a prospective, single-center, randomized controlled trial with three parallel arms conducted at Beijing Tongren Hospital.
- Conditions
- High Myopia, Low Concentration Atropine, Soft Contact Lens, Children
- Trial name
- NCT07406399
- Testing
- soft peripheral defocus contact lenses, Atropine 0.04%, Atropine (0.01%)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Beijing Tongren Hospital
Myopia
Development of Bioluminescent Myopia Prevention and Control Instrument and Evaluation of Its Effect on Myopia
Based on the Tongren Myopia and Amblyopia Therapeutic Apparatus (a 650nm low-level red-light device) developed by the research team in the previous phase, the device was modified by replacing the light source with LED light.
- Trial name
- NCT07208617
- Testing
- RED-light device using LED light source, Control
- Where
- China
- Volunteers
- 206 people
- Sponsor
- Beijing Tongren Hospital
Children With Myopia, Treatment
Clinical Study on the Effectiveness of Diverse Segments Defocus Optimization in Spectacle Lenses for Slowing Myopia Progression
Clinical Trial The goal of this clinical trial is to evaluate the effectiveness of two types of Diverse Segments Defocus Optimization (D.S.D.O.) spectacle lenses in slowing myopia progression in children.
- Conditions
- Children With Myopia, Treatment, Multizone Lens Design for Myopic Defocus, Visual Quality
- Trial name
- NCT07323251
- Testing
- Diverse Segments Defocus Optimization (D.S.D.O.) spectacle lenses
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Myopia
Atropine (0.02%, 0.04%) Combined With Defocus DIMS for Moderate and High Myopia Control
To evaluate the effectiveness and safety of DIMS, low concentration atropine eye drops,and atropine combined with DIMS in controlling axial length and refraction in children with moderate to high myopia.
- Trial name
- atropine (NCT06523504)
- Testing
- DIMS, The 0.02% ATP Group, The 0.04% ATP Group
- Where
- China
- Volunteers
- 410 people
- Sponsor
- Ruihua Wei
Myopia
The Beijing Childhood Eye Study
Axial myopia has emerged as the leading cause of irreversible vision loss in East Asia, driven by its progression to sight-threatening complications including myopic macular degeneration, retinal detachment, open-angle glaucoma…
- Trial name
- BCES (NCT06931444)
- Where
- China
- Volunteers
- 3,760 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Myopia
Effect of Low-level Red-light on Ultra-high Myopia
100 eyes of ultra-high myopia were treated with daily low-level red-light. The age of children ranged from 3 to 16.3 years. The follow-up duration was one year.
- Trial name
- NCT06738095
- Testing
- daily low-level red-light
- Where
- China
- Volunteers
- 57 people
- Sponsor
- Beijing Tongren Hospital
Myopia
Daily Low-level Red Light and 0.01% Low-dose Atropine for Myopia Prevention
To compare the preventive effects of daily low-level red-light and 0.01% low-dose atropine eye drops on myopia.
- Trial name
- NCT06727019
- Testing
- low-level red-light, Atropine (0.01%)
- Where
- China
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Anti-N-Methyl-D-Aspartate Receptor Encephalitis
Efficacy and Safety of Taitacept in Treatment of Refractory or Recurrent Anti-NMDAR/anti-LGI1 Encephalitis
The main objective is to explore the efficacy and safety of Telitacicept in the treatment of refractory/recurrent anti-NMDAR and anti-LGI1 encephalitis.
- Trial name
- NCT06510283
- Testing
- Taitacept
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Beijing Tongren Hospital