Clinical trials: sponsored by Region Stockholm
Depressive Disorder, Major
Aerobic Versus Leisure Group for Adolescents With Depression
The aim is to evaluate aerobic group exercise versus leisure group activities in adolescents with mild to moderate depression. Primary outcome is Children's Depression Rating Scale - Revised (CDRS-R).
- Trial name
- NCT05076214
- Testing
- Aerobic exercise in group, Leisure activities in group
- Where
- 4 sites in Sweden
- Volunteers
- 125 people
- Sponsor
- Lund University Hospital
Asphyxia Neonatorum, Fetal Hypoxia
Sustained Cord Circulation at Emergency Cesarean Section
The goal of this clinical trial is to evaluate if sustained cord circulation during resuscitation improves outcomes for term neonates born by emergency Cesarean section.
- Trial name
- SUCCECS (NCT06540222)
- Testing
- Sustained cord (≥ 180 seconds) resuscitation, Routine (< 60 seconds) cord clamping
- Where
- 12 sites in Sweden
- Volunteers
- 2,200 people
- Sponsor
- Region Skane
Anxiety Mild to Moderate, Inhibition (Psychology)
Tiny Heroes Compared to Treatment as Usual to Decrease and Prevent Anxiety Problems in Young Children - a Randomized Controlled Study
The aim of this randomized controlled trial is to evaluate the effectiveness and cost-effectiveness of Tiny Heroes, a parent-directed internet-delivered cognitive behavioral therapy (iCBT) program for anxiety problems in children…
- Trial name
- NCT07870213
- Testing
- Parent-directed online cognitive behavioral therapy, Treatment as Usual (TAU)
- Volunteers
- 350 people
- Sponsor
- Karolinska Institutet
Bone and Soft Tissue Tumors
Molecular and Clinical Studies of Bone and Soft Tissue Tumors
The goal of this observational study is to learn whether tumors of bone and soft tissue can be sorted into groups by their genes. Today these tumors are named mainly by how they look under a microscope.
- Trial name
- NCT07822204
- Where
- Sweden
- Volunteers
- 50,000 people
- Sponsor
- Karolinska Institutet
Nonsuicidal Self Injury, Nonsuicidal Self-Injury
Psychological Treatment for Adolescents With Self-injury Within Intensive Mental Health Outpatient Services: Randomized Controlled Pilot Trial
The overarching aim of this study is to develop and evaluate a new blended treatment format, which combines face-to-face and digital treatment components, for Emotion Regulation Individual Therapy for Adolescents (ERITA).
- Conditions
- Nonsuicidal Self Injury, Nonsuicidal Self-Injury, Self-Harm
- Trial name
- NCT07755774
- Testing
- Blended ERITA, Treatment as Usual (TAU), Concomitant care
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Obsessive-Compulsive Disorder, Autism Spectrum Disorder
ICBT for OCD in Children With Autism
The purpose of this trial is to evaluate the clinical efficacy, the cost-effectiveness and the effect durability of a therapist-guided, internet-delivered cognitive-behavior therapy intervention for obsessive-compulsive disorder…
- Trial name
- NCT06582225
- Testing
- Internet-delivered exposure and response prevention (I-ERP), Internet-delivered stress management (I-SM)
- Where
- 3 sites in Sweden
- Volunteers
- 220 people
- Sponsor
- Karolinska Institutet
Idiopathic Scoliosis
Trial on Three Treatments for Scoliosis
Idiopathic scoliosis is a three-dimensional structural deformity of the spine that occurs in children. Recent reviews on bracing and exercise treatment have provided some evidence for effect of these interventions.
- Trial name
- CONTRAIS (NCT01761305)
- Testing
- Hypercorrective night-time brace, Scoliosis specific exercises., Self-mediated physical activity.
- Where
- 7 sites in Sweden
- Volunteers
- 135 people
- Sponsor
- Karolinska Institutet
Parental Support, Emotion Regulation
Little ACF (Lilla ABC): Evaluation of a Parental Support Program for Parents of Children Aged 1-2 Years
Society can promote children's mental health at an early stage by creating good conditions with, for example, general parental support programs that are offered to all parents.
- Conditions
- Parental Support, Emotion Regulation, Coping Behavior, Stress, Emotional
- Trial name
- NCT05445141
- Testing
- Little ACF [in Swedish: Lilla ABC], Lectures
- Where
- Sweden
- Volunteers
- 732 people
- Sponsor
- Karolinska Institutet
Self-Harm, Self-Harm, Deliberate
Group Treatment for Self-harming Adolescents and Their Parents: a Randomized Controlled Trial
Adolescent non-suicidal self-injury (NSSI) is common, strongly associated with psychiatric comorbidity and an increased risk of future suicide attempt.
- Conditions
- Self-Harm, Self-Harm, Deliberate, Self-harm Behavior, Non-Suicidal Self Injury
- Trial name
- ERA (NCT07720063)
- Testing
- Emotion Regulation Group Therapy for Self-harming Adolescents, ERA, Functional habits for mental health, FUNK
- Volunteers
- 180 people
- Sponsor
- Karolinska Institutet
Student Education
Systematic Evaluation of Psychotherapy Training: Supervision, Student Learning, and Patient Outcomes
The project is a longitudinal observation study that aims to systematically evaluate selected parts of the material collected within the framework of the psychotherapy training conducted at the Center of Psychotherapy Education…
- Trial name
- NCT06105502
- Testing
- Psychotherapy education
- Where
- Sweden
- Volunteers
- 417 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
Life Style, Health-Related Behavior
A Group Intervention for Promoting Health-related Habits (LEV-G)
Health-related habits influences mental and physical health. Still, treatment of health-related habits, which can help to remedy health problems, is often not done at all or very superficially.
- Conditions
- Life Style, Health-Related Behavior, Disabilities Mental, Disability Physical
- Trial name
- NCT06404632
- Testing
- Lev-g
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Region Stockholm
Juvenile Idiopahtic Arthritis
Improving Outcomes for Juvenile Idiopathic Arthritis
Children and parents often experience uncertainty and stress when juvenile idiopathic arthritis (JIA) is first diagnosed, which creates a need for structured support.
- Trial name
- NCT07659223
- Testing
- The intervention was a one year support program JASP-1
- Where
- Sweden
- Volunteers
- 116 people
- Sponsor
- Region Stockholm
ADHD - Attention Deficit Disorder With Hyperactivity
Evaluation of the Relationship Between Medication, Eye Movements, and Autonomic Nervous System (ANS) Functions in Children and Adolescents With ADHD
An increasing number of children are being diagnosed with ADHD, and the demand for ADHD medication has been rising. Although ADHD medication is often effective, this is unfortunately not the case for all children and adolescents…
- Trial name
- POP-Eye/ANSA (NCT07634809)
- Testing
- metylphenidate
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Umeå University
Cancer
Evaluation of a Psychosocial Support Model for Adolescents and Young Adults Newly Diagnosed With Cancer
Rational: Adolescents and young adults (AYAs) newly diagnosed with cancer is a small but vulnerable group with many psychosocial needs persisting for a long time.
- Trial name
- NCT06979843
- Testing
- A psychosocial model
- Where
- 2 sites in Sweden
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Nonsuicidal Self-Injury, Self-Harm
Internet-delivered Emotion Regulation Individual Therapy or Adolescents (IERITA) With Self-injury Within Child and Adolescent Mental Health Services
The overall purpose of the study is to implement and evaluate IERITA (Internet-delivered Emotion Regulation Individual Therapy for Adolescents) within child and adolescent mental health services for adolescents engaging in…
- Trial name
- NCT07573085
- Testing
- Adaptable IERITA, Standard IERITA, Treatment as usual
- Where
- Sweden
- Volunteers
- 341 people
- Sponsor
- Karolinska Institutet
Cancer, Cancer in Pregnancy
ProspectiveFemaleAYA - Late Effects of Cancer Therapies on Gonadal Function, Fertility, Efficiency of Fertility Preservation Procedures and Pregnancy Outcomes
In the past two decades, the evidence-based knowledge on the prevalence and risk factors for gonads impairment, including infertility, following cancer and numerous cancer treatment regimen has significantly increased.
- Conditions
- Cancer, Cancer in Pregnancy, Infertility, In Vitro Fertilisation (IVF) Treatment
- Trial name
- FemFertilAYA (NCT07622420)
- Volunteers
- 3,000 people
- Sponsor
- Karolinska Institutet
Depression, Anxiety Disorders, Psychiatric Inpatients
Cognitive Behavior Therapy in Psychiatric Inpatient Care
The current project aims to evaluate the extent to which psychological interventions based on Cognitive Behavioral Therapy (CBT), provided within the framework of care, may be helpful for patients in psychiatric inpatient care.
- Trial name
- NCT07503951
- Testing
- Cognitive Behavioral Therapy, treatment as usual (TAU) (Control Group)
- Where
- Sweden
- Volunteers
- 204 people
- Sponsor
- Region Stockholm
Flexor Tendon Injury, Rehabilitation Program
Registry-randomized Comparison of Rehabilitation Regimens After Flexor Tendon Injury in the Thumb
Flexor tendon injuries in the thumb occur across all ages and genders. Each year, approximately 400 patients undergo surgery for a flexor tendon injury in Sweden.
- Conditions
- Flexor Tendon Injury, Rehabilitation Program, Flexor Tendon Rupture, Thumb Injury
- Trial name
- NCT06836349
- Testing
- Early active motion training after operated FPL injury, Immobilisation in plaster cast 4 weeks after operated FPL injury
- Where
- 5 sites in Sweden
- Volunteers
- 380 people
- Sponsor
- Karolinska Institutet
Cancer, Infertility
Late Effects of Cancer Therapies on Gonadal Function, Fertility, Efficiency of Fertility Preservation Procedures and Pregnancy Outcomes
In the past two decades, evidence-based knowledge on the prevalence and risk factors for fertility impairment, including infertility, following cancer and numerous cancer treatment regimens has significantly increased.
- Conditions
- Cancer, Infertility, Late Effects, Female Fertility
- Trial name
- Follow-AYA (NCT07622537)
- Volunteers
- 4,000 people
- Sponsor
- Karolinska Institutet
Major Depressive Disorder
Efficacy and Cost-effectiveness of Internet-delivered CBT for Adolescents With Depression
Adolescent depression is a prevalent and impairing condition that can be effectively treated with Cognitive Behavior Therapy (CBT). However, a majority of adolescents do not have access to CBT.
- Trial name
- IDA (NCT04977856)
- Testing
- Behavioral activation (BA), Regular care within primary or secondary mental health care for children
- Where
- Sweden
- Volunteers
- 219 people
- Sponsor
- Region Stockholm