Clinical trials: sponsored by RenJi Hospital
Multiple Myeloma
Long-term Follow-up Study in Subjects With Multiple Myeloma Previously Treated With GC012F Injection
This is an open-label, multicenter, observational study (non-interventional study) to evaluate the long-term safety, efficacy, and in vivo pharmacokinetic persistence of CAR-T cells in subjects treated with GC012F Injection
- Trial name
- NCT07833046
- Testing
- No Intervention: Observational Cohort
- Where
- China
- Volunteers
- 40 people
- Sponsor
- RenJi Hospital
Primary Hyperoxaluria Type 1, PH1
Phase I Exploratory Study of YOLT-203 in Patients With Primary Hyperoxaluria Type 1 (PH1)
This is a single-arm, open-label, single-dose dose-escalation study. It aims to evaluate the safety and tolerability of YOLT-203 in Chinese patients with Primary Hyperoxaluria Type 1 (PH1), and to preliminarily assess the effect…
- Trial name
- NCT07776626
- Testing
- YOLT-203
- Where
- China
- Volunteers
- 9 people
- Sponsor
- YolTech Therapeutics Co., Ltd
IgA Nephropathy
The Chinese Registry of Prognostic Study of IgA Nephropathy (CRPIGA)
1. Establish an IgAN cohort collaboration group and expert committee to carry out registration research. 2. Construct IgAN structured data set standards, formulate structured data collection templates of diagnosis and treatment …
- Trial name
- NCT04858724
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Ruijin Hospital
Pregnancy Complication, Aortic Dissection
PregnAncy-Related Aortic DISsEction in China
A multicenter observational study on pregnancy-related aortic dissection
- Conditions
- Pregnancy Complication, Aortic Dissection, Marfan Syndrome, Loeys-Dietz Syndrome
- Trial name
- PARADISE (NCT07672210)
- Testing
- Intervention strategies including medication or surgery
- Where
- 4 sites in China
- Volunteers
- 500 people
- Sponsor
- DeltaHealth Hospital · Shanghai
Non-valvular Atrial Fibrillation (NVAF), Venous Thromboembolism (VTE)
Precision Antithrombotic Therapy
The goal of this observational study is to systematically analyze the relationship between trough/peak concentrations of novel oral anticoagulants (NOACs) and antiplatelet drugs with clinical events, aiming to provide high-level…
- Conditions
- Non-valvular Atrial Fibrillation (NVAF), Venous Thromboembolism (VTE), MI(Myocardial Infarction), Ischemic Stroke
- Trial name
- NCT07654634
- Testing
- Not applicable- observational study
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Hepatic Artery Thrombosis, Hepatic Artery Stenosis
Hepatic Artery Stenosis and Thrombosis After Liver Transplantation in Children
The goal of this observational study is to investigate the incidence, current management practices, and outcomes in pediatric patients with HAC after liver transplantation.
- Conditions
- Hepatic Artery Thrombosis, Hepatic Artery Stenosis, Pediatric ALL, Liver Transplant; Complications
- Trial name
- HEPATIC (NCT05818644)
- Where
- Netherlands
- Volunteers
- 583 people
- Sponsor
- University Medical Center Groningen
Intracranial Aneurysm
Real-World Study of Woven EndoBridge for Intracranial Aneurysm Treatment
We designed the Real-World Study of Woven EndoBridge for Intracranial Aneurysm Treatment (WEB-RWS), an ambidirectional, multicenter, post-market real-world study with a prospective active surveillance component.
- Trial name
- WEB-RWS (NCT07620626)
- Testing
- Intrasaccular Flow Disruption Device
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Xuanwu Hospital, Beijing
Growth, Development in Pediatric Liver Transplant Recipients
A Survey on Growth Development in Children After Liver Transplantation
A single-center, large-sample, long-term longitudinal study was conducted to explore the trends and characteristics of changes in growth, development in pediatric liver transplant recipients, with the aim of guiding the…
- Trial name
- NCT07574398
- Where
- China
- Volunteers
- 275 people
- Sponsor
- RenJi Hospital
Acute Myocardial Infarction
Acute Myocardial Infarction Clinical Cohort
This prospective, multicenter, observational cohort study aims to establish a comprehensive clinical database and high-quality biobank for patients with Acute Myocardial Infarction (AMI) in China.
- Trial name
- NCT07522164
- Testing
- Deep multi-omics analysis, Advanced AI-Driven Cardiovascular Imaging
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Shanghai Zhongshan Hospital
Breast Cancer
Disitamab Vedotin (RC48-ADC) in Breast Cancer
To evaluate the efficacy and safety of Disitamab vedotin (RC48-ADC) in patients with breast cancer.
- Trial name
- NCT05851677
- Testing
- Disitamab vedotin
- Where
- China
- Volunteers
- 45 people
- Sponsor
- RenJi Hospital
Hip Dysplasia, Developmental
Diagnostic Efficacy Study of AI System in Screening Infants With Developmental Dysplasia of the Hip
To ascertain the efficacy of the DeepDDH system, a deep learning framework, in enhancing diagnostic accuracy and curtailing follow-up intervals for infants undergoing screening for developmental dysplasia of the hip (DDH), the…
- Trial name
- ASIDDH (NCT06803004)
- Testing
- Junior sonographer measurement of DDH, Senior sonographer measurement of DDH, Automated annotation of the DDH measurement through deep learning
- Where
- China
- Volunteers
- 1,789 people
- Sponsor
- RenJi Hospital
Hemangioma, Cavernous, Central Nervous System
Study on Treatment Decision-Making and Prognostic Follow-Up for Untreated Cerebral Cavernous Malformations
The goal of this observational study is to evaluate and predict the risk associated with cerebral cavernous malformations (CCMs) using advanced artificial intelligence and radiomics analysis technology.
- Trial name
- NCT06214767
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Beijing Tiantan Hospital
Uremia, End Stage Renal Disease on Dialysis
Independent Effects of Visceral Adipose Volume and Density on Patient Survival in Peritoneal Dialysis
It was VAT volume predict patient outcome, while VAT density predicted baseline membrane function in PD patients and reflected peritoneal vascular density and local inflammation status.
- Trial name
- NCT07086430
- Volunteers
- 358 people
- Sponsor
- RenJi Hospital
Pulmonary Hypertension
Construction of Clinical Diagnostic Model for Pulmonary Hypertension
Primary objective: To establish a non-invasive diagnostic model for pulmonary hypertension based on laboratory indicators and echocardiographic parameters.
- Trial name
- NCT06979011
- Where
- China
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Type 1 Primary Hyperoxaluria
Clinical Exploration Study of YOLT-203 in the Treatment of Type 1 Primary Hyperoxaluria (PH1)
This study is a single-arm, open-label, single-dose, dose-escalation, and dose-expansion trial, aiming to assess the safety and tolerability of YOLT-203 in Chinese patients with Primary Hyperoxaluria Type 1 (PH1), and to…
- Trial name
- NCT06511349
- Testing
- YOLT-203
- Where
- China
- Volunteers
- 21 people
- Sponsor
- RenJi Hospital
Pre-Eclampsia
Hydroxychloroquine May be Beneficial for Preeclampsia
The purpose of this research is to investigate the impact of hydroxychloroquine on the incidence of hypertensive pregnancy disorders in women with a history of recurrent spontaneous abortion (RSA).
- Trial name
- NCT06020378
- Testing
- Hydroxychloroquine
- Where
- China
- Volunteers
- 462 people
- Sponsor
- RenJi Hospital
Public Health, Public Health System Research
Early ECG Prediction of Multi-system Disease Cohort Establishment and Follow Up
This registered multicenter study aims to investigate the diagnostic efficacy of artificial intelligence-enhanced electrocardiography (AI-ECG) in detecting multi-system diseases.
- Conditions
- Public Health, Public Health System Research, Multi-system Disease Diagnosis
- Trial name
- EARLY-ECG-PRED (NCT06924580)
- Testing
- ECG screening
- Where
- China
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Quality of Life (QOL), Patient-Reported Outcome Measures (PROMs)
Validation of the EQ-5D-Y-3L and EQ-5D-Y-5L for Paediatric Patients in China
The goal of this observational study is to validate the EQ-5D-Y-3L and EQ-5D-Y-5L in measuring health-related quality of life (HRQoL) for paediatric patients with different health conditions in China.
- Conditions
- Quality of Life (QOL), Patient-Reported Outcome Measures (PROMs), Pneumonia Childhood, Neuroblastoma (NB)
- Trial name
- NCT06873672
- Where
- China
- Volunteers
- 360 people
- Sponsor
- RenJi Hospital
Hip Dysplasia, Developmental
Efficacy Study of DeepDDH System in Screening Infants with Developmental Dysplasia of the Hip (DDH)
To ascertain the efficacy of the DeepDDH system, a deep learning framework, in enhancing diagnostic accuracy and curtailing follow-up intervals for infants undergoing screening for developmental dysplasia of the hip (DDH), the…
- Trial name
- NCT06765525
- Testing
- Junior sonographer measurement of DDH, Senior sonographer measurement of DDH, Automated annotation of the DDH measurement through deep learning
- Where
- China
- Volunteers
- 1,976 people
- Sponsor
- RenJi Hospital
Renal Tumors
Development of AI Model for Renal Tumor Diagnosis Using CT and Lab Tests
This multi-center retrospective study aims to develop a multimodal artificial intelligence diagnostic model using preoperative contrast-enhanced CT images and routine laboratory parameters from patients with renal tumors.
- Trial name
- NCT06761742
- Where
- China
- Volunteers
- 1,922 people
- Sponsor
- RenJi Hospital