Clinical trials: sponsored by St. Olavs Hospital
Self Harm, Borderline Personality Disorder
Predictors of Clinical Course and Treatment Response in DBT Programmes
The project is a collaboration between The National Centre for Suicide Research and Prevention (NSSF) and clinical units with Dialectical Behaviour Therapy (DBT) programmes.
- Trial name
- NCT04318899
- Testing
- Dialectical Behaviour Therapy adapted for adolescents (DBT-A), Dialectical Behaviour Therapy - Standard version (DBT)
- Where
- 5 sites in Norway
- Volunteers
- 250 people
- Sponsor
- Oslo University Hospital
Anorexia Nervosa
Treatment of Anorexia Nervosa in Children and Adolescents: An Integrated Family Based and Metacognitive Approach
The goal of this study is to evaluate the treatment effects of an integrated treatment called Family-based and Metacognitive therapy for patients with Anorexia Nervosa.
- Trial name
- FBT-MCT (NCT06139770)
- Testing
- Family based Metacognitive Therapy.
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- Norwegian University of Science and Technology
Adolescent Idiopathic Scoliosis (AIS)
Hypnosis for Pain and Nausea Reduction in Scoliosis Surgery: An Interventional Study
This study evaluates whether preoperative hypnosis can reduce postoperative pain, nausea, and opioid use in adolescents undergoing scoliosis surgery. Participants aged 12-18 years will receive hypnosis training before surgery.
- Trial name
- HYP-SCOL (NCT07854951)
- Testing
- Hypnosis
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- St. Olavs Hospital
Amyotrophic Lateral Sclerosis, Motor Neuron Disease
Effects of Long Term Ventilation Support on the Quality of Life of ALS Patients and Their Families
Amyotrophic lateral sclerosis (ALS) is a serious rapidly progressive disease of the nervous system. The average survival from the time of diagnosis is two to three years.
- Conditions
- Amyotrophic Lateral Sclerosis, Motor Neuron Disease, Nervous System Diseases, Spinal Cord Diseases
- Trial name
- ALS-LTMV (NCT05744310)
- Testing
- Long term mechanical ventilation support, No long term mechanical ventilation support
- Where
- 9 sites in Norway
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Heart Failure, Left-sided
Cardio-vascular Energy Transfer and Ventriculo-arterial Coupling in Heart Failure
The goal of this pilot study is to investigate energy transfer fram the ventricle to the arteries in patients with heart failure, primary by investigating the total power.
- Trial name
- NCT06200246
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- St. Olavs Hospital
Child Development, Gastrocnemius Equinus
Gastrocnemius Tightness and Foot Pain in Children
Foot and leg pain among otherwise healthy children is a common reason for referral to our pediatric orthopaedics outpatient clinic.
- Trial name
- NCT05862246
- Testing
- Clinical examination
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- St. Olavs Hospital
Cerebral Palsy
Early Remote At-risk Diagnosis for Cerebral Palsy in Follow-up Clinics for High-risk Infants
Cerebral Palsy (CP) is the most common motor dysfunction in childhood. Traditionally, diagnosis is set between 12 and 24 months of age.
- Trial name
- In-Motion (NCT04287166)
- Where
- 3 sites in Norway
- Volunteers
- 100 people
- Sponsor
- St. Olavs Hospital
Asthma, Inflammation
Innovative Steroid Treatment to Reduce Asthma Development in Children After First-time Rhinovirus Induced Wheezing
The overall objective of the study is to determine the efficacy of corticosteroids in preventing recurrent wheezing and asthma in high-risk, first-time severe wheezing children with rhinovirus infection, stratified by rhinovirus…
- Trial name
- INSTAR (NCT03889743)
- Testing
- Dexamethasone treatment during 3 days
- Where
- 8 sites in Finland, Norway and 1 more
- Volunteers
- 280 people
- Sponsor
- St. Olavs Hospital
Post Traumatic Stress Disorder, Rape Sexual Assault
Early Psychological Intervention After Rape
Rape is a common cause of post-traumatic stress disorder (PTSD) among women, as around 30-50% will develop PTSD in the aftermath of rape.
- Conditions
- Post Traumatic Stress Disorder, Rape Sexual Assault, Sexual Dysfunctions, Psychological, Pelvic Floor Myalgia
- Trial name
- EIR (NCT05489133)
- Testing
- Modified prolonged exposure
- Where
- 4 sites in Norway
- Volunteers
- 166 people
- Sponsor
- St. Olavs Hospital
Brain Injuries, Cerebral Palsy
Program Intensive Habilitation (PIH) for Young Children With Early Brain Damage
By longitudinal, prospective research in children with neurodisabilities including severe motor impairments and their parents to explore the beneficial effects of participating in an intensive habilitation program on the child's…
- Conditions
- Brain Injuries, Cerebral Palsy, Motor Skills Disorders, Empowerment
- Trial name
- PIHMulti (NCT05093777)
- Testing
- Program Intensified Habilitation, Habilitation as usual
- Where
- Norway
- Volunteers
- 93 people
- Sponsor
- Sorlandet Hospital HF
Psychiatric Diagnosis, Schizophrenia Disorders
The Key to Integrated Trauma Treatment in Psychosis Trial
Schizophrenia spectrum disorders (SSDs) have a significant trauma etiology: trauma has been reported in 65 - 80% in this patient group and have a negative impact on prognosis.
- Conditions
- Psychiatric Diagnosis, Schizophrenia Disorders, Psychological Trauma, Historical
- Trial name
- KIT (NCT06608706)
- Testing
- Eye Movement Desensitization and Reprocessing (EMDR) for psychosis
- Where
- 11 sites in Norway
- Volunteers
- 187 people
- Sponsor
- Haukeland University Hospital
Preterm, Patent Ductus Arteriosus
NeoDoppler: New Ultrasound Technology for Continuous Monitoring of Cerebral Circulation Pilot
Non-invasive tools for monitoring of course of disease are important and necessary in the treatment of pre-term/premature infants and sick neonates.
- Conditions
- Preterm, Patent Ductus Arteriosus, Sepsis, Asphyxia
- Trial name
- CE-NeoDoppler (NCT06646250)
- Testing
- NeoDoppler - CE certified
- Where
- Norway
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- St. Olavs Hospital
Pneumothorax Iatrogenic Postprocedural, Air Embolism as A Complication of Medical Care
Complications After CT-guided Lung Biopsies at St. Olavs Hospital
At St. Olavs Hospital, a prospective collection of data on complications related to CT-guided lung biopsies has been conducted over several years as part of quality control study.
- Conditions
- Pneumothorax Iatrogenic Postprocedural, Air Embolism as A Complication of Medical Care, Hemoptysis
- Trial name
- KELSO (NCT07528170)
- Testing
- CT-guided needle biopsy of lung nodule
- Volunteers
- 1,200 people
- Sponsor
- St. Olavs Hospital
Autism Spectrum Disorder
Enabling Parents of Children With Autism Spectrum Disorders - a Randomized Controlled Trial of Parenting Programs
Autism spectrum disorders (ASD) are disabling and impairing conditions affecting 1% of children in Norway. ASD is hallmarked by severe social deficit and lack of independence causing reliance on supportive systems throughout…
- Trial name
- ENACT (NCT05750095)
- Testing
- Incredible Years Autism Spectrum and Language Delay Programme, First Aid for Parents
- Where
- 3 sites in Norway
- Volunteers
- 240 people
- Sponsor
- Haukeland University Hospital
Bronchiolitis Acute, Lower Respiratory Tract and Lung Infections
Modern Technologies in Lower Respiratory Tract Infections in Children
Lower respiratory tract infections (LRTIs) are a significant cause of childhood morbidity and mortality globally, particularly in low-income countries.
- Conditions
- Bronchiolitis Acute, Lower Respiratory Tract and Lung Infections, Pediatric Lung Ultrasound, Tidal Volume
- Trial name
- MoT-LRTI (NCT07381790)
- Testing
- lung ultrasound, Tidal-flow volume loops
- Where
- 2 sites in Norway
- Volunteers
- 200 people
- Sponsor
- Helse Møre og Romsdal HF
Feeding and Eating Disorders
Comparing Enhanced Cognitive-behavior Therapy and Family-based Treatment for Adolescents With an Eating Disorder
The goal of this randomized controlled clinical trial is to compare the efficacy of outpatient family-based treatment versus enhanced cognitive behavior therapy for children and adolescents with eating disorders.
- Trial name
- CogFam (NCT06256380)
- Testing
- Enhanced Cognitive-behavior therapy for adolescents with an eating disorder, Family-based therapy for adolescents with an eating disorder
- Where
- 5 sites in Norway
- Volunteers
- 200 people
- Sponsor
- Oslo University Hospital
Feeding and Eating Disorders, Anorexia Nervosa
Cognitive Training for Patients With Eating Disorders
Eating disorders are severe mental illnesses, mainly affecting adolescent- and young adult women. The prognoses for eating disorders are relatively poor, and a large part of patients with these illnesses do not benefit from…
- Conditions
- Feeding and Eating Disorders, Anorexia Nervosa, Bulimia Nervosa, Binge-Eating Disorder
- Trial name
- TCRTRCT (NCT03808467)
- Testing
- Cognitive Remediation Therapy, Treatment as usual
- Where
- 3 sites in Norway
- Volunteers
- 100 people
- Sponsor
- Norwegian University of Science and Technology
Colon Cancer
Endoscopic Therapy Or Surgery for Early Colon Cancer
The trial is a randomized head-to-head comparison of the benefits, harms and burdens of endoscopic full-thickness resection (eFTR), a novel, minimally invasive endoscopic treatment modality, for early colon cancer as compared to…
- Trial name
- ETHOS (NCT06940947)
- Testing
- eFTR, Surgery
- Where
- Poland
- Volunteers
- 434 people
- Sponsor
- Norwegian Department of Health and Social Affairs
Premature Birth
Skin-to-skin After Delivery in Preterm Infants Born at 28-32 Weeks of Gestation
The aim of the study is to investigate physiological response, social/emotional response and general movements in preterm infants when they are given skin-to-skin contact with the mother (intervention) or standard care…
- Trial name
- NCT02024854
- Testing
- skin-to-skin, standard care
- Where
- 4 sites in Canada, Norway
- Volunteers
- 108 people
- Sponsor
- Norwegian University of Science and Technology
Post-partum Hemorrhage
REBOA in Life-threatening Postpartum Hemorrhage (PPH) in Uganda
Background Maternal mortality rates in many low-income countries (LMICs) remain high. The most prominent cause is bleeding after birth, called postpartum haemorrhage (PPH).
- Trial name
- REBOA-PPH (NCT05598502)
- Testing
- REBOA, Resuscitative Endovascular Occlusion of the Aorta, National guidelines
- Where
- Uganda
- Volunteers
- 95 people
- Sponsor
- Centre For International Health